Upregulation of β3-adrenergic receptor expression in the atrium of rats with chronic heart failure

Journal of Cardiovascular Pharmacology and Therapeutics

Volumn 18, Issue 2, 2013, Pages 133-137

  Zhao, Qiang ^a   Zeng, Fang ^a   Liu, Jiang Bo ^a   He, Yun ^a   Li, Biao ^a   Jiang, Zuo Feng ^a   Wu, Tong Guo ^a   Wang, Le Xin ^b  

^a GUANGZHOU RED CROSS HOSPITAL   (China)

^b CHARLES STURT UNIVERSITY   (Australia)

Author keywords

3 adrenergic receptor; atrium; heart failure; hemodynamics; remodeling

Indexed keywords

4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; BETA 3 ADRENERGIC RECEPTOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; HEART ATRIUM; HEART FAILURE; HEART INDEX; HEART LEFT ATRIUM; HEART LEFT VENTRICLE PRESSURE; HEART RIGHT ATRIUM; HEART WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SYSTOLIC BLOOD PRESSURE;

ANIMALS; CHRONIC DISEASE; HEART ATRIA; HEART FAILURE; MALE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-3; RNA, MESSENGER; UP-REGULATION;

EID: 84873696643     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248412460123     Document Type: Article

References (15)

1. Ursino MG, Vasina V, Raschi E, Crema F, De Ponti F. The β3-adrenoceptor as a therapeutic target: current perspectives. Pharmacol Res. 2009 ; 59 (4). 221-234
2. Zhao Q, Wu TG, Jiang ZF, Chen GW, Lin Y, Wang LX. Effect of β-blockers on β3-adrenoceptor expression in chronic heart failure. Cardiovasc Drugs Ther. 2007 ; 21 (2). 85-90
3. Amour J, Loyer X, Le Guen M, et al. Altered contractile response due to increased β3-adrenoceptor stimulation in diabetic cardiomyopathy: the role of nitric oxide synthase 1-derived nitric oxide. Anesthesiology. 2007 ; 107 (3). 452-460
4. Chen Z, Miao G, Liu M, et al. Age-related up-regulation of β3-adrenergic receptor in heart-failure rats. J Recept Signal Transduct Res. 2010 ; 30 (4). 227-233
5. Dessy C. Balligand JL. β3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives. Adv Pharmacol. 2010 ; 59: 135-163
6. Mercadier JJ, Lompre M, Wisneusky C, et al. Myosin isoenzyme changes in several models of rat cardiac hypertrophy. Circ Res. 1981 ; 49: 525-532
7. Kong YH, Li WM, Tian Y. Effect of β3-adrenoreceptors agonist on β3-adrenoreceptors expression and myocyte apoptosis in a rat model of heart failure. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 ; 16 (3). 142-147
8. Dinçer UD, Bidasee KR, Güner S, Tay A, Ozçelikay AT, Altan VM. The effect of diabetes on expression of β1-, β2- and β3-adrenoceptors in rat hearts. Diabetes. 2001 ; 50 (2). 455-461
9. Sharma D, Li G, Xu G, Liu Y, Xu Y. Atrial remodeling in atrial fibrillation and some related microRNAs. Cardiology. 2011 ; 120 (2). 111-121
10. Barbier J, Rannou-Bekono F, Marchais J, Carre TF. Alterations of β3-adrenoceptors expression and their myocardial functional effects in physiological model of chronic exercise-induced cardiac hypertrophy. Mol Cell Biochem. 2007 ; 300 (1-2). 69-75
11. Cheng HJ, Zhang ZS, Onishi K, Tanguy S, Carré F. Upregulation of functional β3-adrenergic receptor in the failing canine myocardium. Circ Res. 2001 ; 89 (7). 599-606
12. Skeberdis VA, Gendviliene V, Zablockaite D, et al. β3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current. J Clin Invest. 2008 ; 118: 3219-3227
13. Christ T, Molenaar P, Klenowski PM, Ravens U, Kaumann AJ. Human atrial β1L-adrenoceptor but not β3-adrenoceptor activation increases force and Ca2+ current at physiological temperature. Br J Pharmacol. 2011 ; 162 (4). 823-839
14. Kaumann AJ, Molenaar P. The low-affinity site of the β1-adrenoceptor and its relevance to cardiovascular pharmacology. Pharmacol Ther. 2008 ; 118 (3). 303-336
15. Yu J, Li W, Li Y, et al. Activation of β3-adrenoceptor promotes rapid pacing-induced atrial electrical remodeling in rabbits. Cell Physiol Biochem. 2011 ; 28 (1). 87-96