Increase of protein yield in high five cells in a single-use perfusion bioreactor by medium replacement

Chemie-Ingenieur-Technik

Volumn 85, Issue 1-2, 2013, Pages 111-117

  Rausch, Mareike ^a   Pörtner, Ralf ^b   Knäblein, Jörg ^a  

^a BAYER PHARMA AG   (Germany)

^b HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

High Five cells; Insect cells; Medium replacement; Perfusion; Single use bioreactor; Wave bioreactor

Indexed keywords

HIGH FIVE CELLS; INSECT CELLS; MEDIUM REPLACEMENT; PERFUSION; SINGLE USE; WAVE BIOREACTORS;

BIOREACTORS; CELLS; PROTEINS;

CYTOLOGY;

EID: 84873686070     PISSN: 0009286X     EISSN: 15222640     Source Type: Journal    
DOI: 10.1002/cite.201200121     Document Type: Article

References (26)

1. C. B. Elias et al., Methods Mol. Biol. 2007, 388, 225-246.
2. N. Carinhas et al., Appl. Microbiol. Biotechnol. 2009, 81 (6), 1041-1049.
3. M. S. Donaldson, M. L. Shuler, Biotechnol. Prog. 1998, 14, 573-579.
4. C. F. Shen et al., Cytotechnology 2007, 54 (1), 25-34.
5. L. C. Chan et al., J. Virol. Methods 2002, 105 (1), 87-98.
6. L. Ikonomou et al., In Vitro Cell Dev. Biol.: Anim. 2001, 37, 549-559.
7. F. Krammer et al., Mol. Biotechnol. 2010, 45 (3), 226-234.
8. M. Rhiel et al., Biotechnol. Bioeng. 1997, 55, 909-920.
9. C. Bédard et al., Cytotechnology 1994, 15, 129-138.
10. L. C. L. Chan et al., Biotechnol. Bioeng. 1998, 59, 178-188.
11. V. M. Gorenflo et al., Cytotechnology 2004, 44 (3), 93-102.
12. B. A. Jardin et al., Biotechnol. Bioeng. 2007, 97 (2), 332-345.
13. C. B. Elias et al., Biotechnol. Bioeng. 2000, 68 (4), 381-388.
14. J. C. Drugmand, Dissertation, Université catholique de Louvain, Louvain-la-Neuve 2007.
15. L. Ikonomou et al., Cytotechnology 2004, 44, 67-76.
16. D. A. Lindsay, M. J. Betenbaugh, Biotechnol. Bioeng. 1992, 39, 614-618.
17. S. Reuveny et al., Biotechnol. Bioeng. 1993, 42, 235-239.
18. R. L. Tom et al., Appl. Microbiol. Biotechnol. 1995, 44, 53-58.
19. A. W. Caron et al., Biotechnol. Bioeng. 1994, 43, 881-891.
20. E. Chico, V. Jäger, Biotechnol. Bioeng. 2000, 7, 574-586.
21. R. Eibl, D. Eibl, Adv. Biochem. Eng. Biotechnol. 2009, 112, 183-207.
22. R. Eibl et al., Appl. Microbiol. Biotechnol. 2010, 86 (1), 41-49.
23. V. Singh, Cytotechnology 1999, 30, 149-158.
24. W. Weber et al., Cytotechnology 2002, 38, 77-85.
25. R. Ohashi et al., in Animal Cell Technology: From Target to Market (Eds: E. Lindner-Olsson et al.), Kluwer Academic Publishers, Dordrecht 2001.
26. Y. J. Tang, Biotechnol. Prog. 2007, 23, 255-264.