MiR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1

International Journal of Oncology

Volumn 42, Issue 2, 2013, Pages 757-766

  Xu, Weiyi ^a   Liu, Mingfa ^a   Peng, Xueling ^a   Zhou, Peng ^a   Zhou, Jianwen ^a   Xu, Ke ^a   Xu, Haixiong ^a   Jiang, Songshan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cell proliferation; MiR 24 3p; MiR 27a 3p; MXI1

Indexed keywords

MICRORNA; MICRORNA 24; MICRORNA 24 3P; MICRORNA 27A 3P; MXI1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL PROLIFERATION; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MICRORNAS; TUMOR SUPPRESSOR PROTEINS;

EID: 84873684110     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1742     Document Type: Article

References (47)

1. Surawicz TS, Davis F, Freels S, Laws ER Jr and Menck HR: Brain tumor survival: results from the National Cancer Data Base. J Neurooncol 40: 151-160, 1998.
2. Furnari FB, Fenton T, Bachoo RM, et al: Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21: 2683-2710, 2007.
3. Xu X, Xi L, Zeng J and Yao Q: A functional +61G?A polymorphism in epidermal growth factor is associated with glioma risk among Asians. PLoS One 7: e41470, 2012.
4. Lu J, Getz G, Miska EA, et al: MicroRNA expression profiles classify human cancers. Nature 435: 834-838, 2005.
5. Dong H, Siu H, Luo L, Fang X, Jin L and Xiong M: Investigation gene and microRNA expression in glioblastoma. BMC Genomics 11 (Suppl 3): S16, 2010.
6. Chen CZ: MicroRNAs as oncogenes and tumor suppressors. N Engl J Med 353: 1768-1771, 2005.
7. Calin GA and Croce CM: MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866, 2006.
8. Bushati N and Cohen SM: microRNA functions. Annu Rev Cell Dev Biol 23: 175-205, 2007.
9. Bartel DP: MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233, 2009.
10. Wang D, Qiu C, Zhang H, Wang J, Cui Q and Yin Y: Human microRNA oncogenes and tumor suppressors show significantly different biological patterns: from functions to targets. PLoS One 5: e13067, 2010.
11. Chhabra R, Dubey R and Saini N: Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases. Mol Cancer 9: 232, 2010.
12. Lal A, Navarro F, Maher CA, et al: miR-24 inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to 'seedless' 3'UTR microRNA recognition elements. Mol Cell 35: 610-625, 2009.
13. Lal LS, Miller LA, Arbuckle R, et al: Disparities in outpatient antidepressant prescribing patterns and determinants of resource utilization at a tertiary care cancer center. J Support Oncol 7: 237-244, 2009.
14. Jones KJ, Skinner A, Xu L, Sun J and Mueller K: The AHRQ Hospital Survey on Patient Safety Culture: A Tool to Plan and Evaluate Patient Safety Programs. In: Advances in Patient Safety: New Directions and Alternative Approaches. Henriksen K, Battles JB, Keyes MA, Grady ML (eds). Vol 2. Culture and Redesign. Agency for Healthcare Research and Quality, Rockville, MD, 2008.
15. Fukuda Y, Kawasaki H and Taira K: Exploration of human miRNA target genes in neuronal differentiation. Nucleic Acids Symp Ser (Oxf): 341-342, 2005.
16. Qin W, Shi Y, Zhao B, et al: miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells. PLoS One 5: e9429, 2010.
17. Cheng AM, Byrom MW, Shelton J and Ford LP: Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 33: 1290-1297, 2005.
18. Feng J, Iwama A, Satake M and Kohu K: MicroRNA-27 enhances differentiation of myeloblasts into granulocytes by post-transcriptionally downregulating Runx1. Br J Haematol 145: 412-423, 2009.
19. McDaneld TG, Smith TP, Doumit ME, et al: MicroRNA transcriptome profiles during swine skeletal muscle development. BMC Genomics 10: 77, 2009.
20. Wang T and Xu Z: miR-27 promotes osteoblast differentiation by modulating Wnt signaling. Biochem Biophys Res Commun 402: 186-189, 2010.
21. Mertens-Talcott SU, Chintharlapalli S, Li X and Safe S: The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res 67: 11001-11011, 2007.
22. Ji J, Zhang J, Huang G, Qian J, Wang X and Mei S: Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett 583: 759-766, 2009.
23. Lee Y, Kim M, Han J, et al: MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23: 4051-4060, 2004.
24. Sun F, Wang J, Pan Q, et al: Characterization of function and regulation of miR-24-1 and miR-31. Biochem Biophys Res Commun 380: 660-665, 2009.
25. Ciafrè SA, Galardi S, Mangiola A, et al: Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 334: 1351-1358, 2005.
26. Landgraf P, Rusu M, Sheridan R, et al: A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414, 2007.
27. Henriksson M and Lüscher B: Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res 68: 109-182, 1996.
28. Schreiber-Agus N and DePinho RA: Repression by the Mad(Mxi1)-Sin3 complex. Bioessays 20: 808-818, 1998.
29. Fujimoto M, Fults DW, Thomas GA, et al: Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme. Genomics 4: 210-214, 1989.
30. Rasheed BK, Fuller GN, Friedman AH, Bigner DD and Bigner SH: Loss of heterozygosity for 10q loci in human gliomas. Genes Chromosomes Cancer 5: 75-82, 1992.
31. Ransom DT, Ritland SR, Moertel CA, et al: Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas. Genes Chromosomes Cancer 5: 357-374, 1992.
32. Carter BS, Ewing CM, Ward WS, et al: Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proc Natl Acad Sci USA 87: 8751-8755, 1990.
33. Lundgren R, Mandahl N, Heim S, Limon J, Henrikson H and Mitelman F: Cytogenetic analysis of 57 primary prostatic adenocarcinomas. Genes Chromosomes Cancer 4: 16-24, 1992.
34. Ko JY, Yoo KH, Lee HW and Park JH: Mxi1 regulates cell proliferation through insulin-like growth factor binding protein 3. Biochem Biophys Res Commun 415: 36-41, 2011.
35. Tsao CC, Teh BT, Jonasch E, et al: Inhibition of Mxi1 suppresses HIF-2alpha-dependent renal cancer tumorigenesis. Cancer Biol Ther 7: 1619-1627, 2008.
36. Ebert MS, Neilson JR and Sharp PA: MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4: 721-726, 2007.
37. Catuogno S, Esposito CL, Quintavalle C, Condorelli G, de Franciscis V and Cerchia L: Nucleic acids in human glioma treatment: innovative approaches and recent results. J Signal Transduct 2012: 735135, 2012.
38. Esquela-Kerscher A and Slack FJ: Oncomirs -microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269, 2006.
39. Feng SY, Dong CG, Wu WK, Wang XJ, Qiao J and Shao JF: Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells. Mol Med Rep 6: 275-281, 2012.
40. Guttilla IK and White BA: Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells. J Biol Chem 284: 23204-23216, 2009.
41. Zhu H, Wu H, Liu X, et al: Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 76: 582-588, 2008.
42. Wechsler DS, Shelly CA, Petroff CA and Dang CV: MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells. Cancer Res 57: 4905-4912, 1997.
43. Schreiber-Agus N, Meng Y, Hoang T, et al: Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth. Nature 393: 483-487, 1998.
44. Kuczyk MA, Serth J, Bokemeyer C, et al: The MXI1 tumor suppressor gene is not mutated in primary prostate cancer. Oncol Rep 5: 213-216, 1998.
45. Mauleon I, Lombard MN, Muñoz-Alonso MJ, Cañelles M and Leon J: Kinetics of myc-max-mad gene expression during hepatocyte proliferation in vivo: Differential regulation of mad family and stress-mediated induction of c-myc. Mol Carcinog 39: 85-90, 2004.
46. Swartling FJ: Myc proteins in brain tumor development and maintenance. Ups J Med Sci 117: 122-131, 2012.
47. Gustafson WC and Weiss WA: Myc proteins as therapeutic targets. Oncogene 29: 1249-1259, 2010.