Increased cold and heat pain thresholds influence the thermal grill illusion in schizophrenia

European Journal of Pain (United Kingdom)

Volumn 17, Issue 2, 2013, Pages 200-209

  Boettger, M K ^a,b   Grossmann, D ^a   Bar K J ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COLD; CONTROLLED STUDY; FEMALE; HEAT; HUMAN; ILLUSION; MALE; MENTAL PATIENT; NOCICEPTION; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PARANOID SCHIZOPHRENIA; PRIORITY JOURNAL; STIMULUS; TEMPERATURE; THERMAL GRILL ILLUSION;

ADULT; AGED; COLD TEMPERATURE; FEMALE; FUNCTIONAL LATERALITY; HOT TEMPERATURE; HUMANS; ILLUSIONS; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN PERCEPTION; PAIN THRESHOLD; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA, PARANOID; SCHIZOPHRENIC PSYCHOLOGY; SEX CHARACTERISTICS; YOUNG ADULT;

EID: 84873666210     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1002/j.1532-2149.2012.00188.x     Document Type: Article

References (41)

1. Andreasen, N.C., Arndt, S., Miller, D., Flaum, M., Nopoulos, P. (1995). Correlational studies of the Scale for the Assessment of Negative Symptoms and the Scale for the Assessment of Positive Symptoms: An overview and update. Psychopathology 28, 7-17.
2. Balu, D.T., Coyle, J.T. (2011). Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neurosci Biobehav Rev 35, 848-870.
3. Bär, K.J., Brehm, S., Boettger, M.K., Boettger, S., Wagner, G., Sauer, H. (2005). Pain perception in major depression depends on pain modality. Pain 117, 97-103.
4. Bär, K.J., Terhaar, J., Boettger, M.K., Boettger, S., Berger, S., Weiss, T. (2011). Pseudohypoalgesia on the skin: A novel view on the paradox of pain perception in depression. J Clin Psychopharmacol 31, 103-107.
5. Becker, A., Grecksch, G., Zernig, G., Ladstaetter, E., Hiemke, C., Schmitt, U. (2009). Haloperidol and risperidone have specific effects on altered pain sensitivity in the ketamine model of schizophrenia. Psychopharmacology (Berl) 202, 579-587.
6. Blumensohn, R., Ringler, D., Eli, I. (2002). Pain perception in patients with schizophrenia. J Nerv Ment Dis 190, 481-483.
7. Boettger, M.K., Greiner, W., Rachow, T., Bruhl, C., Bär, K.J. (2010). Sympathetic skin response following painful electrical stimulation is increased in major depression. Pain 149, 130-134.
8. Boettger, M.K., Schwier, C., Bär, K.J. (2011). Sad mood increases pain sensitivity upon thermal grill illusion stimulation: Implications for central pain processing. Pain 152, 123-130.
9. Borgwardt, S.J., Picchioni, M.M., Ettinger, U., Toulopoulou, T., Murray, R., McGuire, P.K. (2010). Regional gray matter volume in monozygotic twins concordant and discordant for schizophrenia. Biol Psychiatry 67, 956-964.
10. Bouhassira, D., Kern, D., Rouaud, J., Pelle-Lancien, E., Morain, F. (2005). Investigation of the paradoxical painful sensation ('illusion of pain') produced by a thermal grill. Pain 114, 160-167.
11. Chen, Y., McBain, R., Norton, D., Ongur, D. (2011). Schizophrenia patients show augmented spatial frame illusion for visual and visuomotor tasks. Neuroscience 172, 419-426.
12. Craig, A.D. (2008). Can the basis for central neuropathic pain be identified by using a thermal grill? Pain 135, 215-216.
13. Craig, A.D., Bushnell, M.C. (1994). The thermal grill illusion: Unmasking the burn of cold pain. Science 265, 252-255.
14. Craig, A.D., Reiman, E.M., Evans, A., Bushnell, M.C. (1996). Functional imaging of an illusion of pain. Nature 384, 258-260.
15. Defrin, R., Benstein-Sheraizin, A., Bezalel, A., Mantzur, O., Arendt-Nielsen, L. (2008). The spatial characteristics of the painful thermal grill illusion. Pain 138, 577-586.
16. Dworkin, R.H. (1994). Pain insensitivity in schizophrenia: A neglected phenomenon and some implications. Schizophr Bull 20, 235-248.
17. Eagleman, D.M. (2001). Visual illusions and neurobiology. Nat Rev Neurosci 2, 920-926.
18. Fillingim, R.B., Maixner, W., Kincaid, S., Silva, S. (1998). Sex differences in temporal summation but not sensory-discriminative processing of thermal pain. Pain 75, 121-127.
19. First, M.B. (2005). Clinical utility: A prerequisite for the adoption of a dimensional approach in DSM. J Abnorm Psychol 114, 560-564.
20. Fishbain, D.A., Cutler, R.B., Lewis, J., Cole, B., Rosomoff, R.S., Rosomoff, H.L. (2004). Do the second-generation 'atypical neuroleptics' have analgesic properties? A structured evidence-based review. Pain Med 5, 359-365.
21. Fundytus, M.E. (2001). Glutamate receptors and nociception: Implications for the drug treatment of pain. CNS Drugs 15, 29-58.
22. Green, B.G. (2002). Synthetic heat at mild temperatures. Somatosens Mot Res 19, 130-138.
23. Green, B.G., Pope, J.V. (2003). Innocuous cooling can produce nociceptive sensations that are inhibited during dynamic mechanical contact. Exp Brain Res 148, 290-299.
24. Jochum, T., Letzsch, A., Greiner, W., Wagner, G., Sauer, H., Bär, K.J. (2006). Influence of antipsychotic medication on pain perception in schizophrenia. Psychiatry Res 142, 151-156.
25. Kantrowitz, J.T., Butler, P.D., Schecter, I., Silipo, G., Javitt, D.C. (2009). Seeing the world dimly: The impact of early visual deficits on visual experience in schizophrenia. Schizophr Bull 35, 1085-1094.
26. Kay, S.R., Fiszbein, A., Opler, L.A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13, 261-276.
27. Kraepelin, E. (1919). Dementia Praecox and Paraphrenia (Edinburgh: Livingston).
28. Leitman, D.I., Sehatpour, P., Higgins, B.A., Foxe, J.J., Silipo, G., Javitt, D.C. (2010). Sensory deficits and distributed hierarchical dysfunction in schizophrenia. Am J Psychiatry 167, 818-827.
29. Li, X., Petrini, L., Wang, L., Defrin, R., Arendt-Nielsen, L. (2009). The importance of stimulus parameters for the experience of the thermal grill illusion. Neurophysiol Clin 39, 275-282.
30. Moberg, P.J., Agrin, R., Gur, R.E., Gur, R.C., Turetsky, B.I., Doty, R.L. (1999). Olfactory dysfunction in schizophrenia: A qualitative and quantitative review. Neuropsychopharmacology 21, 325-340.
31. Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia 9, 97-113.
32. Pessoa, V.F., Monge-Fuentes, V., Simon, C.Y., Suganuma, E., Tavares, M.C. (2008). The Muller-Lyer illusion as a tool for schizophrenia screening. Rev Neurosci 19, 91-100.
33. Potvin, S., Marchand, S. (2008). Hypoalgesia in schizophrenia is independent of antipsychotic drugs: A systematic quantitative review of experimental studies. Pain 138, 70-78.
34. Potvin, S., Stip, E., Tempier, A., Pampoulova, T., Bentaleb, L.A., Lalonde, P., Lipp, O., Goffaux, P., Marchand, S. (2008). Pain perception in schizophrenia: No changes in diffuse noxious inhibitory controls (DNIC) but a lack of pain sensitization. J Psychiatr Res 42, 1010-1016.
35. Price, D.D., McHaffie, J.G., Larson, M.A. (1989). Spatial summation of heat-induced pain: Influence of stimulation area and spatial separation on perceived pain sensation intensity and unpleasantness. J Neurophysiol 62, 1270-1279.
36. Rolke, R., Baron, R., Maier, C., Tolle, T.R., Treede, R.D., Beyer, A., Binder, A., Birbaumer, N., Birklein, F., Botefur, I.C., Braune, S., Flor, H., Huge, V., Klug, R., Landwehrmeyer, G.B., Magerl, W., Maihöfner, C., Rolko, C., Schaub, C., Scherens, A., Sprenger, T., Valet, M., Wasserka, B. (2006). Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference values. Pain 123, 231-243.
37. Salter, M.W., Pitcher, G.M. (2012). Dysregulated Src upregulation of NMDA receptor activity: A common link in chronic pain and schizophrenia. FEBS J 279, 2-11.
38. Schwier, C., Kliem, A., Boettger, M.K., Bär, K.J. (2010). Increased cold-pain thresholds in major depression. J Pain 11, 287-290.
39. Surguladze, S.A., Chkonia, E.D., Kezeli, A.R., Roinishvili, M.O., Stahl, D., David, A.S. (2012). The McCollough effect and facial emotion discrimination in patients with schizophrenia and their unaffected relatives. Schizophr Bull 38(3), 599-607.
40. Terhaar, J., Boettger, M.K., Schwier, C., Wagner, G., Israel, A.K., Bär, K.J. (2010). Increased sensitivity to heat pain after sad mood induction in female patients with major depression. Eur J Pain 14, 559-563.
41. Thunberg, T. (1896). Förnimmelserna vid till samma ställe lokasirerad, samtidigtb pagaende köld och värmeretning. Uppsala Läkkfören Föhr, 489-495.