Interaction of polyhexamethylene biguanide hydrochloride (PHMB) with phosphatidylcholine containing o/w emulsion and consequences for microbicidal efficacy and cytotoxicity

Chemico-Biological Interactions

Volumn 201, Issue 1-3, 2013, Pages 58-64

  Müller, Gerald ^a   Koburger, Torsten ^b   Kramer, Axel ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b HYGIENE NORD GMBH   (Germany)

Author keywords

Antimicrobial efficacy; Cytotoxicity; Egg phosphatidylcholine; O w emulsion; PHMB; Polyhexamethylene biguanide

Indexed keywords

COSMOCIL; PHOSPHATIDYLCHOLINE; POLY(HEXAMETHYLENEBIGUANIDE); UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL STRAIN L 929; CENTRIFUGATION; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; EMULSION; FILTRATION; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BIGUANIDES; CELL LINE; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; EMULSIONS; FIBROBLASTS; MICE; MICROBIAL SENSITIVITY TESTS; PHOSPHATIDYLCHOLINES; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 84873645764     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.01.001     Document Type: Article

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