-
1
-
-
0028925756
-
Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR): The structural and functional conservation in human, bovine, and murine EPCR
-
Fukudome K, Esmon CT, (1995) Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR): The structural and functional conservation in human, bovine, and murine EPCR. J Biol Chem 270: 5571-5577.
-
(1995)
J Biol Chem
, vol.270
, pp. 5571-5577
-
-
Fukudome, K.1
Esmon, C.T.2
-
2
-
-
0030776168
-
Human protein C receptor is present primarily on endothelium of large blood vessels: Implications for the control of the protein C pathway
-
Laszik Z, Mitro A, Taylor FB Jr, Ferrell G, Esmon CT, (1997) Human protein C receptor is present primarily on endothelium of large blood vessels: Implications for the control of the protein C pathway. Circulation 96: 3633-3640.
-
(1997)
Circulation
, vol.96
, pp. 3633-3640
-
-
Laszik, Z.1
Mitro, A.2
Taylor Jr., F.B.3
Ferrell, G.4
Esmon, C.T.5
-
3
-
-
0141819138
-
The Protein C Pathway
-
Esmon CT, (2003) The Protein C Pathway. Chest 124: 26S-32S.
-
(2003)
Chest
, vol.124
-
-
Esmon, C.T.1
-
4
-
-
0036124011
-
Factor V and thrombotic disease: description of a janus-faced protein
-
Nicolaes GA, Dahlbäck B, (2002) Factor V and thrombotic disease: description of a janus-faced protein. Arterioscler Thromb Vasc Biol 22: 530-538.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 530-538
-
-
Nicolaes, G.A.1
Dahlbäck, B.2
-
5
-
-
0033820789
-
Phylogenetic and functional relationships between coagulation and the innate immune response
-
Opal SM, (2000) Phylogenetic and functional relationships between coagulation and the innate immune response. Crit Care Med 28: S77-S80.
-
(2000)
Crit Care Med
, vol.28
-
-
Opal, S.M.1
-
6
-
-
0030742589
-
Identification of functional endothelial protein C receptor in human plasma
-
Kurosawa S, Stearns-Kurosawa DJ, Hidari N, Esmon CT, (1997) Identification of functional endothelial protein C receptor in human plasma. J Clin. Invest 100: 411.
-
(1997)
J Clin Invest
, vol.100
, pp. 411
-
-
Kurosawa, S.1
Stearns-Kurosawa, D.J.2
Hidari, N.3
Esmon, C.T.4
-
7
-
-
0034668005
-
The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18
-
Kurosawa S, Esmon CT, Stearns-Kurosawa DJ, (2000) The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18. J Immunol 165: 4697-4703.
-
(2000)
J Immunol
, vol.165
, pp. 4697-4703
-
-
Kurosawa, S.1
Esmon, C.T.2
Stearns-Kurosawa, D.J.3
-
8
-
-
0031973176
-
Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: lack of correlation with thrombomodulin suggests involvement of different pathological processes
-
Kurosawa S, Stearns-Kurosawa DJ, Carson CW, D'Angelo A, Della Valle P, et al. (1998) Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: lack of correlation with thrombomodulin suggests involvement of different pathological processes. Blood 91: 725.
-
(1998)
Blood
, vol.91
, pp. 725
-
-
Kurosawa, S.1
Stearns-Kurosawa, D.J.2
Carson, C.W.3
D'Angelo, A.4
Della Valle, P.5
-
9
-
-
0029790055
-
The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
-
Stearns-Kurosawa DJ, Kurosawa S, Mollica JS, Ferrell GL, Esmon CT, (1996) The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci 93: 10212.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 10212
-
-
Stearns-Kurosawa, D.J.1
Kurosawa, S.2
Mollica, J.S.3
Ferrell, G.L.4
Esmon, C.T.5
-
10
-
-
0035815747
-
Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis
-
Joyce DE, Gelbert L, Ciaccia A, DeHoff B, Grinnell BW, (2001) Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis. J Biol Chem 276: 11199-11203.
-
(2001)
J Biol Chem
, vol.276
, pp. 11199-11203
-
-
Joyce, D.E.1
Gelbert, L.2
Ciaccia, A.3
DeHoff, B.4
Grinnell, B.W.5
-
11
-
-
0037352279
-
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
-
Cheng T, Liu D, Griffin JH, Fernández JA, Castellino F, et al. (2003) Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. Nat Med 9: 338-42.
-
(2003)
Nat Med
, vol.9
, pp. 338-342
-
-
Cheng, T.1
Liu, D.2
Griffin, J.H.3
Fernández, J.A.4
Castellino, F.5
-
12
-
-
0034660464
-
Activated protein C reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation
-
Mizutani A, Okajima K, Uchiba M, Noguchi T, (2000) Activated protein C reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation. Blood 95: 3781-3787.
-
(2000)
Blood
, vol.95
, pp. 3781-3787
-
-
Mizutani, A.1
Okajima, K.2
Uchiba, M.3
Noguchi, T.4
-
13
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, et al. (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344: 699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.F.5
-
14
-
-
0027982876
-
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
-
Springer TA, (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314.
-
(1994)
Cell
, vol.76
, pp. 301-314
-
-
Springer, T.A.1
-
15
-
-
0345552244
-
The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells
-
Xia Y, Vetvicka V, Yan J, Hanikyrova M, Mayadas T, et al. (1999) The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J Immunol 162: 2281-90.
-
(1999)
J Immunol
, vol.162
, pp. 2281-2290
-
-
Xia, Y.1
Vetvicka, V.2
Yan, J.3
Hanikyrova, M.4
Mayadas, T.5
-
16
-
-
0025283473
-
A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/Cd18)
-
Altieri DC, Agbanyo FR, Plescia J, Ginsberg MH, Edgington TS, et al. (1990) A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/Cd18). J Biol Chem 265: 12119-12122.
-
(1990)
J Biol Chem
, vol.265
, pp. 12119-12122
-
-
Altieri, D.C.1
Agbanyo, F.R.2
Plescia, J.3
Ginsberg, M.H.4
Edgington, T.S.5
-
17
-
-
0037104688
-
The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, aMß2)
-
Schwarz M, Nordt T, Bode C, Peter K, (2002) The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, aMß2). Thromb Res 107: 121-128.
-
(2002)
Thromb Res
, vol.107
, pp. 121-128
-
-
Schwarz, M.1
Nordt, T.2
Bode, C.3
Peter, K.4
-
18
-
-
0029166397
-
Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1)
-
Diamond MS, Alon R, Parkos CA, Quinn MT, Springer TA, (1995) Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1). J Cell Biol 130: 1473-1482.
-
(1995)
J Cell Biol
, vol.130
, pp. 1473-1482
-
-
Diamond, M.S.1
Alon, R.2
Parkos, C.A.3
Quinn, M.T.4
Springer, T.A.5
-
19
-
-
0033527375
-
Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18)
-
Peter K, Schwarz M, Conradt C, Nordt T, Moser M, et al. (1999) Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18). Circulation 100: 1533-1539.
-
(1999)
Circulation
, vol.100
, pp. 1533-1539
-
-
Peter, K.1
Schwarz, M.2
Conradt, C.3
Nordt, T.4
Moser, M.5
-
20
-
-
0025759969
-
Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation
-
Diamond MS, Staunton DE, Marlin SD, Springer TA, (1991) Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell 65: 961-971.
-
(1991)
Cell
, vol.65
, pp. 961-971
-
-
Diamond, M.S.1
Staunton, D.E.2
Marlin, S.D.3
Springer, T.A.4
-
21
-
-
0041528155
-
Adhesion of monocytes to medical steel as used for vascular stents is mediated by the integrin receptor Mac-1 (CD11b/CD18; alphaM beta2) and can be inhibited by semiconductor coating
-
Schuler P, Assefa D, Ylänne J, Basler N, Olschewski M, et al. (2003) Adhesion of monocytes to medical steel as used for vascular stents is mediated by the integrin receptor Mac-1 (CD11b/CD18; alphaM beta2) and can be inhibited by semiconductor coating. Cell Commun Adhes 10: 17-26.
-
(2003)
Cell Commun Adhes
, vol.10
, pp. 17-26
-
-
Schuler, P.1
Assefa, D.2
Ylänne, J.3
Basler, N.4
Olschewski, M.5
-
22
-
-
34147152321
-
Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents
-
Eisenhardt SU, Schwarz M, Schallner N, Soosairajah J, Bassler N, et al. (2007) Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents. Blood 109: 3521-3528.
-
(2007)
Blood
, vol.109
, pp. 3521-3528
-
-
Eisenhardt, S.U.1
Schwarz, M.2
Schallner, N.3
Soosairajah, J.4
Bassler, N.5
-
23
-
-
10644294901
-
Promotion of leukocyte adhesion by a novel interaction between vitronectin and the beta2 integrin Mac-1 (alphaM beta2, CD11b/CD18)
-
Kanse SM, Matz RL, Preissner KT, Peter K, (2004) Promotion of leukocyte adhesion by a novel interaction between vitronectin and the beta2 integrin Mac-1 (alphaM beta2, CD11b/CD18). Arterioscler Thromb Vasc Biol 24: 2251-2256.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 2251-2256
-
-
Kanse, S.M.1
Matz, R.L.2
Preissner, K.T.3
Peter, K.4
-
24
-
-
0034009976
-
Metalloproteolytic release of endothelial cell protein C receptor
-
Xu J, Qu D, Esmon NL, Esmon CT, (1999) Metalloproteolytic release of endothelial cell protein C receptor. J Biol Chem 275: 6038-6044.
-
(1999)
J Biol Chem
, vol.275
, pp. 6038-6044
-
-
Xu, J.1
Qu, D.2
Esmon, N.L.3
Esmon, C.T.4
-
25
-
-
0030034186
-
Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
-
Murakami K, Okajima K, Uchiba M, Johno M, Nakagaki T, et al. (1996) Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats. Blood 87: 642-647.
-
(1996)
Blood
, vol.87
, pp. 642-647
-
-
Murakami, K.1
Okajima, K.2
Uchiba, M.3
Johno, M.4
Nakagaki, T.5
-
26
-
-
0023122016
-
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon
-
Taylor FB Jr, Chang A, Esmon CT, D'Angelo A, Vigano-D'Angelo S, et al. (1987) Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest 79: 918-925.
-
(1987)
J Clin Invest
, vol.79
, pp. 918-925
-
-
Taylor Jr., F.B.1
Chang, A.2
Esmon, C.T.3
D'Angelo, A.4
Vigano-D'Angelo, S.5
-
27
-
-
8144228302
-
Gene expression profiling of inflamed human endothelial cells and influence of activated protein C
-
Franscini N, Bachli EB, Blau N, Leikauf MS, Schaffner A, et al. (2004) Gene expression profiling of inflamed human endothelial cells and influence of activated protein C. Circulation. 110: 2903-2909.
-
(2004)
Circulation
, vol.110
, pp. 2903-2909
-
-
Franscini, N.1
Bachli, E.B.2
Blau, N.3
Leikauf, M.S.4
Schaffner, A.5
-
28
-
-
0034917319
-
Recombinant human activated protein C: a system modulator of vascular function for treatment of severe sepsis
-
Grinnell BW, Joyce D, (2001) Recombinant human activated protein C: a system modulator of vascular function for treatment of severe sepsis. Crit Care Med Suppl (53-0):: 60-61.
-
(2001)
Crit Care Med
, Issue.53 SUPPL.
, pp. 60-61
-
-
Grinnell, B.W.1
Joyce, D.2
-
29
-
-
34447119424
-
Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease
-
Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, et al. (2007) Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J Clin Invest 117: 1951-1960.
-
(2007)
J Clin Invest
, vol.117
, pp. 1951-1960
-
-
Scaldaferri, F.1
Sans, M.2
Vetrano, S.3
Graziani, C.4
De Cristofaro, R.5
|