Targeted zwitterionic near-infrared fluorophores for improved optical imaging

Nature Biotechnology

Volumn 31, Issue 2, 2013, Pages 148-153

  Choi, Hak Soo ^a   Gibbs, Summer L ^a   Lee, Jeong Heon ^a   Kim, Soon Hee ^a,b   Ashitate, Yoshitomo ^a   Liu, Fangbing ^a   Hyun, Hoon ^a   Park, Gwang Li ^a   Xie, Yang ^a   Bae, Soochan ^a   Henary, Maged ^c   Frangioni, John V ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Chonbuk National University   (South Korea)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; DETECTABILITY; IMAGE GUIDED SURGERY; IMMUNOBLOTTING; IN-VITRO; IN-VIVO; KEY DETERMINANTS; LOW BACKGROUND; NEAR INFRA RED; NEAR-INFRARED FLUOROPHORES; OPTICAL IMAGING; RGD PEPTIDE; SIGNAL STRENGTHS; SIGNAL-TO-BACKGROUND RATIO; THERAPEUTIC APPLICATION; TUMOR MODELS;

ANTIBODIES; INFRARED DEVICES; OPTICAL IMAGE STORAGE; TUMORS;

FLUOROPHORES;

CONTRAST MEDIUM; FIBRINOGEN; UNCLASSIFIED DRUG; ZW 800 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER DIAGNOSIS; CONJUGATION; CONTROLLED STUDY; DRUG SYNTHESIS; FLUORESCENCE IMAGING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURFACE CHARGE; ZWITTERIONIC NEAR INFRARED FLUORESCENCE;

ANIMALS; ANTIBODIES; CELL LINE, TUMOR; FIBRINOGEN; FLUORESCENT DYES; HUMANS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NEOPLASMS; OPTICAL IMAGING; PEPTIDES, CYCLIC; QUATERNARY AMMONIUM COMPOUNDS; SIGNAL-TO-NOISE RATIO; SULFONIC ACIDS; SURGERY, COMPUTER-ASSISTED;

EID: 84873588948     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2468     Document Type: Article

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