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Volumn 381, Issue 9865, 2013, Pages 484-495

Acute myeloid leukaemia in adults

Author keywords

[No Author keywords available]

Indexed keywords

ANTIEMETIC AGENT; ARSENIC TRIOXIDE; AZACITIDINE; BREAKPOINT CLUSTER REGION PROTEIN; CD135 ANTIGEN; CLADRIBINE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; FLUDARABINE PHOSPHATE; GEMTUZUMAB OZOGAMICIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IDARUBICIN; MITOXANTRONE; PROTEIN KAT6A; PROTEIN P53; PROTEIN RBM15; RAS PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

EID: 84873580363     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(12)61727-9     Document Type: Conference Paper
Times cited : (450)

References (140)
  • 1
    • 0026079804 scopus 로고
    • Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia
    • CH Pui, RC Ribeiro, ML Hancock et al. Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia N Engl J Med 325 1991 1682 1687
    • (1991) N Engl J Med , vol.325 , pp. 1682-1687
    • Pui, C.H.1    Ribeiro, R.C.2    Hancock, M.L.3
  • 2
    • 84864021804 scopus 로고    scopus 로고
    • Cytogenetics, not just previous therapy, determines the course of therapy-related myeloid neoplasms
    • RA Larson Cytogenetics, not just previous therapy, determines the course of therapy-related myeloid neoplasms J Clin Oncol 30 2012 2300 2302
    • (2012) J Clin Oncol , vol.30 , pp. 2300-2302
    • Larson, R.A.1
  • 3
    • 78649964060 scopus 로고    scopus 로고
    • Targeting DNA repair pathways in AML
    • AD D'Andrea Targeting DNA repair pathways in AML Best Pract Res Clin Haematol 23 2010 469 473
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 469-473
    • D'Andrea, A.D.1
  • 5
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
    • G Marcucci, T Haferlach, H Döhner Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications J Clin Oncol 29 2011 475 486
    • (2011) J Clin Oncol , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Döhner, H.3
  • 7
    • 84873587159 scopus 로고    scopus 로고
    • Acute myeloid leukaemia in adults: Mast cell leukaemia and other mast cell neoplasms
    • W.K. Hong R.C. Bast W.N. Hait 8th edn. PMPH USA Shelton
    • C Schiffer, RM Stone Acute myeloid leukaemia in adults: mast cell leukaemia and other mast cell neoplasms WK Hong RC Bast WN Hait Holland-Frei Cancer Medicine 8th edn. 2010 PMPH USA Shelton
    • (2010) Holland-Frei Cancer Medicine
    • Schiffer, C.1    Stone, R.M.2
  • 8
    • 81555228423 scopus 로고    scopus 로고
    • Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
    • Y Shen, YM Zhu, X Fan et al. Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia Blood 118 2011 5593 5603
    • (2011) Blood , vol.118 , pp. 5593-5603
    • Shen, Y.1    Zhu, Y.M.2    Fan, X.3
  • 9
    • 80052468964 scopus 로고    scopus 로고
    • Stem cell gene expression programs influence clinical outcome in human leukemia
    • K Eppert, K Takenaka, ER Lechman et al. Stem cell gene expression programs influence clinical outcome in human leukemia Nat Med 17 2011 1086 1093
    • (2011) Nat Med , vol.17 , pp. 1086-1093
    • Eppert, K.1    Takenaka, K.2    Lechman, E.R.3
  • 10
    • 84863337617 scopus 로고    scopus 로고
    • Clonal architecture of secondary acute myeloid leukemia
    • MJ Walter, D Shen, L Ding et al. Clonal architecture of secondary acute myeloid leukemia N Engl J Med 366 2012 1090 1098
    • (2012) N Engl J Med , vol.366 , pp. 1090-1098
    • Walter, M.J.1    Shen, D.2    Ding, L.3
  • 11
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • L Ding, TJ Ley, DE Larson et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing Nature 481 2012 506 510
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3
  • 12
    • 1842614240 scopus 로고    scopus 로고
    • Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): Results from CALGB 8461
    • JC Byrd, AS Ruppert, K Mrozek et al. Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461 J Clin Oncol 22 2004 1087 1094
    • (2004) J Clin Oncol , vol.22 , pp. 1087-1094
    • Byrd, J.C.1    Ruppert, A.S.2    Mrozek, K.3
  • 13
    • 3042586012 scopus 로고    scopus 로고
    • Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461
    • CD Bloomfield, AS Ruppert, K Mrozek et al. Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461 Ann Hematol 83 suppl 2004 S84 S85
    • (2004) Ann Hematol , vol.83 , Issue.SUPPL.
    • Bloomfield, C.D.1    Ruppert, A.S.2    Mrozek, K.3
  • 14
    • 33745184051 scopus 로고    scopus 로고
    • A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies
    • ML Slovak, H Gundacker, CD Bloomfield et al. A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies Leukemia 20 2006 1295 1297
    • (2006) Leukemia , vol.20 , pp. 1295-1297
    • Slovak, M.L.1    Gundacker, H.2    Bloomfield, C.D.3
  • 15
    • 42949122111 scopus 로고    scopus 로고
    • High EVI1 levels predict adverse outcome in acute myeloid leukemia: Prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated
    • S Lugthart, E van Drunen, Y van Norden et al. High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated Blood 111 2008 4329 4337
    • (2008) Blood , vol.111 , pp. 4329-4337
    • Lugthart, S.1    Van Drunen, E.2    Van Norden, Y.3
  • 16
    • 80051609304 scopus 로고    scopus 로고
    • Outcome of patients with acute myeloid leukemia with monosomal karyotype who undergo hematopoietic cell transplantation
    • M Fang, B Storer, E Estey et al. Outcome of patients with acute myeloid leukemia with monosomal karyotype who undergo hematopoietic cell transplantation Blood 118 2011 1404 1490
    • (2011) Blood , vol.118 , pp. 1404-1490
    • Fang, M.1    Storer, B.2    Estey, E.3
  • 17
    • 0037114753 scopus 로고    scopus 로고
    • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
    • JC Byrd, K Mrozek, RK Dodge et al. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461) Blood 100 2002 4325 4336
    • (2002) Blood , vol.100 , pp. 4325-4336
    • Byrd, J.C.1    Mrozek, K.2    Dodge, R.K.3
  • 18
    • 77955914238 scopus 로고    scopus 로고
    • Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
    • D Grimwade, RK Hills, AV Moorman et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials Blood 116 2010 354 365
    • (2010) Blood , vol.116 , pp. 354-365
    • Grimwade, D.1    Hills, R.K.2    Moorman, A.V.3
  • 19
    • 0034672269 scopus 로고    scopus 로고
    • Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study
    • ML Slovak, KJ Kopecky, PA Cassileth et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study Blood 96 2000 4075 4083
    • (2000) Blood , vol.96 , pp. 4075-4083
    • Slovak, M.L.1    Kopecky, K.J.2    Cassileth, P.A.3
  • 20
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • JW Vardiman, J Thiele, DA Arber et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes Blood 114 2009 937 951
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 21
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • H Dohner, EH Estey, S Amadori et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet Blood 115 2010 453 474
    • (2010) Blood , vol.115 , pp. 453-474
    • Dohner, H.1    Estey, E.H.2    Amadori, S.3
  • 22
    • 79251585937 scopus 로고    scopus 로고
    • The prognostic and functional role of microRNAs in acute myeloid leukemia
    • G Marcucci, K Mrozek, MD Radmacher, R Garzon, CD Bloomfield The prognostic and functional role of microRNAs in acute myeloid leukemia Blood 117 2011 1121 1129
    • (2011) Blood , vol.117 , pp. 1121-1129
    • Marcucci, G.1    Mrozek, K.2    Radmacher, M.D.3    Garzon, R.4    Bloomfield, C.D.5
  • 23
    • 77449140390 scopus 로고    scopus 로고
    • Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: A Cancer and Leukemia Group B study
    • H Becker, G Marcucci, K Maharry et al. Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study J Clin Oncol 28 2010 596 604
    • (2010) J Clin Oncol , vol.28 , pp. 596-604
    • Becker, H.1    Marcucci, G.2    Maharry, K.3
  • 24
    • 79251556241 scopus 로고    scopus 로고
    • Acute myeloid leukemia with mutated nucleophosmin (NPM1): Is it a distinct entity?
    • B Falini, MP Martelli, N Bolli et al. Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity? Blood 117 2011 1109 1120
    • (2011) Blood , vol.117 , pp. 1109-1120
    • Falini, B.1    Martelli, M.P.2    Bolli, N.3
  • 25
    • 77449146413 scopus 로고    scopus 로고
    • Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome
    • A Dufour, F Schneider, KH Metzeler et al. Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome J Clin Oncol 28 2010 570 577
    • (2010) J Clin Oncol , vol.28 , pp. 570-577
    • Dufour, A.1    Schneider, F.2    Metzeler, K.H.3
  • 26
    • 63849241865 scopus 로고    scopus 로고
    • Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome
    • BJ Wouters, B Lowenberg, CAWL Erpelinck-Verschueren, PJ Valk, R Delwel Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome Blood 113 2009 3088 3091
    • (2009) Blood , vol.113 , pp. 3088-3091
    • Wouters, B.J.1    Lowenberg, B.2    Erpelinck-Verschueren, C.3    Valk, P.J.4    Delwel, R.5
  • 27
    • 77649211990 scopus 로고    scopus 로고
    • The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: Overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA
    • AK Burnett, RK Hills, C Green et al. The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA Blood 115 2010 948 956
    • (2010) Blood , vol.115 , pp. 948-956
    • Burnett, A.K.1    Hills, R.K.2    Green, C.3
  • 28
    • 41949087055 scopus 로고    scopus 로고
    • Prognostic relevance of FLT3-TKD mutations in AML: The combination matters - An analysis of 3082 patients
    • U Bacher, C Haferlach, W Kern, T Haferlach, S Schnittger Prognostic relevance of FLT3-TKD mutations in AML: the combination matters - an analysis of 3082 patients Blood 111 2008 2527 2537
    • (2008) Blood , vol.111 , pp. 2527-2537
    • Bacher, U.1    Haferlach, C.2    Kern, W.3    Haferlach, T.4    Schnittger, S.5
  • 29
    • 84855190284 scopus 로고    scopus 로고
    • Meta-analysis for the potential application of FLT3-TKD mutations as prognostic indicator in non-promyelocytic AML
    • W Li, L Zhang, L Huang, Y Mi, J Wang Meta-analysis for the potential application of FLT3-TKD mutations as prognostic indicator in non-promyelocytic AML Leuk Res 36 2012 186 189
    • (2012) Leuk Res , vol.36 , pp. 186-189
    • Li, W.1    Zhang, L.2    Huang, L.3    Mi, Y.4    Wang, J.5
  • 30
    • 33748467435 scopus 로고    scopus 로고
    • Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): A Cancer and Leukemia Group B Study
    • P Paschka, G Marcucci, AS Ruppert et al. Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study J Clin Oncol 24 2006 3904 3911
    • (2006) J Clin Oncol , vol.24 , pp. 3904-3911
    • Paschka, P.1    Marcucci, G.2    Ruppert, A.S.3
  • 31
    • 77950612017 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML
    • JA Pollard, TA Alonzo, RB Gerbing et al. Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML Blood 115 2010 2309 2372
    • (2010) Blood , vol.115 , pp. 2309-2372
    • Pollard, J.A.1    Alonzo, T.A.2    Gerbing, R.B.3
  • 32
    • 67651065502 scopus 로고    scopus 로고
    • Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
    • O Abdel-Wahab, A Mullally, C Hedvat et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies Blood 114 2009 144 147
    • (2009) Blood , vol.114 , pp. 144-147
    • Abdel-Wahab, O.1    Mullally, A.2    Hedvat, C.3
  • 33
    • 80053620171 scopus 로고    scopus 로고
    • TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics
    • WC Chou, SC Chou, CY Liu et al. TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics Blood 118 2011 3803 3810
    • (2011) Blood , vol.118 , pp. 3803-3810
    • Chou, W.C.1    Chou, S.C.2    Liu, C.Y.3
  • 34
    • 84856477048 scopus 로고    scopus 로고
    • Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia
    • I Fried, C Bodner, MM Pichler et al. Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia Haematologica 97 2012 246 250
    • (2012) Haematologica , vol.97 , pp. 246-250
    • Fried, I.1    Bodner, C.2    Pichler, M.M.3
  • 35
    • 84862909358 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia-stability during disease evolution and the clinical implication
    • HA Hou, YY Kuo, CY Liu et al. DNMT3A mutations in acute myeloid leukemia-stability during disease evolution and the clinical implication Blood 119 2012 559 568
    • (2012) Blood , vol.119 , pp. 559-568
    • Hou, H.A.1    Kuo, Y.Y.2    Liu, C.Y.3
  • 36
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • TJ Ley, L Ding, MJ Walter et al. DNMT3A mutations in acute myeloid leukemia N Engl J Med 363 2010 2424 2433
    • (2010) N Engl J Med , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 37
    • 77957759961 scopus 로고    scopus 로고
    • The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status
    • CL Green, CM Evans, RK Hills, AK Burnett, DC Linch, RE Gale The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status Blood 116 2010 2779 2782
    • (2010) Blood , vol.116 , pp. 2779-2782
    • Green, C.L.1    Evans, C.M.2    Hills, R.K.3    Burnett, A.K.4    Linch, D.C.5    Gale, R.E.6
  • 38
    • 77952536841 scopus 로고    scopus 로고
    • IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
    • Wu YZ et al
    • G Marcucci, K Maharry Wu YZ et al IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study J Clin Oncol 28 2010 2348 2355
    • (2010) J Clin Oncol , vol.28 , pp. 2348-2355
    • Marcucci, G.1    Maharry, K.2
  • 39
    • 84255176496 scopus 로고    scopus 로고
    • ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category
    • KH Metzeler, H Becker, K Maharry et al. ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category Blood 118 2011 6920 6929
    • (2011) Blood , vol.118 , pp. 6920-6929
    • Metzeler, K.H.1    Becker, H.2    Maharry, K.3
  • 40
    • 79953124734 scopus 로고    scopus 로고
    • Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
    • M Levis, F Ravandi, ES Wang et al. Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse Blood 117 2011 3294 3301
    • (2011) Blood , vol.117 , pp. 3294-3301
    • Levis, M.1    Ravandi, F.2    Wang, E.S.3
  • 41
    • 46749108531 scopus 로고    scopus 로고
    • MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
    • M Jongen-Lavrencic, SM Sun, MK Dijkstra, PJ Valk, B Lowenberg MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia Blood 111 2008 5078 5085
    • (2008) Blood , vol.111 , pp. 5078-5085
    • Jongen-Lavrencic, M.1    Sun, S.M.2    Dijkstra, M.K.3    Valk, P.J.4    Lowenberg, B.5
  • 42
    • 55549103713 scopus 로고    scopus 로고
    • Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: A Cancer and Leukemia Group B Study
    • G Marcucci, K Maharry, MD Radmacher et al. Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study J Clin Oncol 26 2008 5078 5087
    • (2008) J Clin Oncol , vol.26 , pp. 5078-5087
    • Marcucci, G.1    Maharry, K.2    Radmacher, M.D.3
  • 43
    • 33644866304 scopus 로고    scopus 로고
    • BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: Prognostic implications
    • CD Baldus, C Thiede, S Soucek, CD Bloomfield, E Thiel, G Ehninger BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: prognostic implications J Clin Oncol 24 2006 790 797
    • (2006) J Clin Oncol , vol.24 , pp. 790-797
    • Baldus, C.D.1    Thiede, C.2    Soucek, S.3    Bloomfield, C.D.4    Thiel, E.5    Ehninger, G.6
  • 44
    • 33845263501 scopus 로고    scopus 로고
    • High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
    • M Heuser, G Beutel, J Krauter et al. High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics Blood 108 2006 3898 3905
    • (2006) Blood , vol.108 , pp. 3898-3905
    • Heuser, M.1    Beutel, G.2    Krauter, J.3
  • 45
    • 33644830601 scopus 로고    scopus 로고
    • Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: A Cancer and Leukemia Group B study
    • G Marcucci, CD Baldus, AS Ruppert et al. Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study J Clin Oncol 23 2005 9234 9242
    • (2005) J Clin Oncol , vol.23 , pp. 9234-9242
    • Marcucci, G.1    Baldus, C.D.2    Ruppert, A.S.3
  • 46
    • 19944427850 scopus 로고    scopus 로고
    • Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
    • B Falini, C Mecucci, E Tiacci et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype N Engl J Med 352 2005 254 266
    • (2005) N Engl J Med , vol.352 , pp. 254-266
    • Falini, B.1    Mecucci, C.2    Tiacci, E.3
  • 47
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • RE Gale, C Green, C Allen et al. The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia Blood 111 2008 2776 2784
    • (2008) Blood , vol.111 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, C.3
  • 48
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • S Schnittger, C Schoch, M Dugas et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease Blood 100 2002 59 66
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3
  • 49
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • C Thiede, C Steudel, B Mohr et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis Blood 99 2002 4326 4335
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 50
    • 0035476264 scopus 로고    scopus 로고
    • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
    • SP Whitman, KJ Archer, L Feng et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study Cancer Res 61 2001 7233 7239
    • (2001) Cancer Res , vol.61 , pp. 7233-7239
    • Whitman, S.P.1    Archer, K.J.2    Feng, L.3
  • 51
    • 28444473100 scopus 로고    scopus 로고
    • Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations
    • K Dohner, RF Schlenk, M Habdank et al. Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations Blood 106 2005 3740 3746
    • (2005) Blood , vol.106 , pp. 3740-3746
    • Dohner, K.1    Schlenk, R.F.2    Habdank, M.3
  • 52
    • 42949142189 scopus 로고    scopus 로고
    • Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
    • RF Schlenk, K Dohner, J Krauter et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia N Engl J Med 358 2008 1909 1918
    • (2008) N Engl J Med , vol.358 , pp. 1909-1918
    • Schlenk, R.F.1    Dohner, K.2    Krauter, J.3
  • 53
    • 84863393263 scopus 로고    scopus 로고
    • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
    • JP Patel, M Gonen, ME Figueroa et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia N Engl J Med 366 2012 1079 1089
    • (2012) N Engl J Med , vol.366 , pp. 1079-1089
    • Patel, J.P.1    Gonen, M.2    Figueroa, M.E.3
  • 54
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • TJ Ley, ER Mardis, L Ding et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome Nature 456 2008 66 72
    • (2008) Nature , vol.456 , pp. 66-72
    • Ley, T.J.1    Mardis, E.R.2    Ding, L.3
  • 55
    • 77953460959 scopus 로고    scopus 로고
    • Acute myeloid leukemia stem cells: Seek and destroy
    • GJ Roboz, M Guzman Acute myeloid leukemia stem cells: seek and destroy Expert Rev Hematol 2 2009 663 672
    • (2009) Expert Rev Hematol , vol.2 , pp. 663-672
    • Roboz, G.J.1    Guzman, M.2
  • 56
    • 77956163003 scopus 로고    scopus 로고
    • Epigenetic mechanisms in AML - A target for therapy
    • Y Oki, JP Issa Epigenetic mechanisms in AML - a target for therapy Cancer Treat Res 145 2010 19 40
    • (2010) Cancer Treat Res , vol.145 , pp. 19-40
    • Oki, Y.1    Issa, J.P.2
  • 58
    • 44849121373 scopus 로고    scopus 로고
    • Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia
    • B Hackanson, KL Bennett, RM Brena et al. Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia Cancer Res 68 2008 3142 3151
    • (2008) Cancer Res , vol.68 , pp. 3142-3151
    • Hackanson, B.1    Bennett, K.L.2    Brena, R.M.3
  • 59
    • 42949137382 scopus 로고    scopus 로고
    • Clinically useful prognostic factors in acute myeloid leukemia
    • F Ferrara, S Palmieri, F Leoni Clinically useful prognostic factors in acute myeloid leukemia Crit Rev Oncol Hematol 66 2008 181 193
    • (2008) Crit Rev Oncol Hematol , vol.66 , pp. 181-193
    • Ferrara, F.1    Palmieri, S.2    Leoni, F.3
  • 60
    • 81255175041 scopus 로고    scopus 로고
    • Prediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: A novel paradigm for treatment assignment
    • RB Walter, M Othus, G Borthakur et al. Prediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment J Clin Oncol 29 2011 4417 4423
    • (2011) J Clin Oncol , vol.29 , pp. 4417-4423
    • Walter, R.B.1    Othus, M.2    Borthakur, G.3
  • 61
    • 78650171819 scopus 로고    scopus 로고
    • Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: A web-based application for prediction of outcomes
    • U Krug, C Röllig, A Koschmieder et al. Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes Lancet 376 2010 2000 2008
    • (2010) Lancet , vol.376 , pp. 2000-2008
    • Krug, U.1    Röllig, C.2    Koschmieder, A.3
  • 62
    • 0035282068 scopus 로고    scopus 로고
    • Platelet transfusion for patients with cancer: Clinical practice guidelines of the American Society of Clinical Oncology
    • CA Schiffer, KC Anderson, CL Bennett et al. Platelet transfusion for patients with cancer: clinical practice guidelines of the American Society of Clinical Oncology J Clin Oncol 19 2001 1519 1538
    • (2001) J Clin Oncol , vol.19 , pp. 1519-1538
    • Schiffer, C.A.1    Anderson, K.C.2    Bennett, C.L.3
  • 63
    • 33846462456 scopus 로고    scopus 로고
    • Posaconazole vs fluconazole or itraconazole prophylaxis in patients with neutropenia
    • OA Cornely, J Maertens, DJ Winston et al. Posaconazole vs fluconazole or itraconazole prophylaxis in patients with neutropenia N Engl J Med 356 2007 348 359
    • (2007) N Engl J Med , vol.356 , pp. 348-359
    • Cornely, O.A.1    Maertens, J.2    Winston, D.J.3
  • 64
    • 70349451999 scopus 로고    scopus 로고
    • High-dose daunorubicin in older patients with acute myeloid leukemia
    • B Lowenberg, GJ Ossenkoppele, W van Putten et al. High-dose daunorubicin in older patients with acute myeloid leukemia N Engl J Med 361 2009 1235 1248
    • (2009) N Engl J Med , vol.361 , pp. 1235-1248
    • Lowenberg, B.1    Ossenkoppele, G.J.2    Van Putten, W.3
  • 65
    • 0037158110 scopus 로고    scopus 로고
    • The outcomes and costs of acute myeloid leukemia among the elderly
    • J Menzin, K Lang, CC Earle, D Kerney, R Mallick The outcomes and costs of acute myeloid leukemia among the elderly Arch Intern Med 162 2002 1597 1603
    • (2002) Arch Intern Med , vol.162 , pp. 1597-1603
    • Menzin, J.1    Lang, K.2    Earle, C.C.3    Kerney, D.4    Mallick, R.5
  • 66
    • 84860317991 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the real world: Why population-based registries are needed
    • G Juliusson, V Lazarevic, AS Horstedt, O Hagberg, M Hoglund Acute myeloid leukemia in the real world: why population-based registries are needed Blood 119 2012 3890 3899
    • (2012) Blood , vol.119 , pp. 3890-3899
    • Juliusson, G.1    Lazarevic, V.2    Horstedt, A.S.3    Hagberg, O.4    Hoglund, M.5
  • 67
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
    • BD Cheson, JM Bennett, KJ Kopecky et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia J Clin Oncol 21 2003 4642 4649
    • (2003) J Clin Oncol , vol.21 , pp. 4642-4649
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3
  • 68
    • 84855838173 scopus 로고    scopus 로고
    • Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia
    • F Buccisano, L Maurillo, MI Del Principe et al. Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia Blood 119 2012 332 341
    • (2012) Blood , vol.119 , pp. 332-341
    • Buccisano, F.1    Maurillo, L.2    Del Principe, M.I.3
  • 69
    • 77953483479 scopus 로고    scopus 로고
    • Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: Results of the AML02 multicentre trial
    • JE Rubnitz, H Inaba, G Dahl et al. Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial Lancet Oncol 11 2010 543 552
    • (2010) Lancet Oncol , vol.11 , pp. 543-552
    • Rubnitz, J.E.1    Inaba, H.2    Dahl, G.3
  • 70
    • 77950480200 scopus 로고    scopus 로고
    • Effect of complete remission and responses less than complete remission on survival in acute myeloid leukemia: A combined Eastern Cooperative Oncology Group, Southwest Oncology Group, and M. D. Anderson Cancer Center Study
    • RB Walter, HM Kantarjian, X Huang et al. Effect of complete remission and responses less than complete remission on survival in acute myeloid leukemia: a combined Eastern Cooperative Oncology Group, Southwest Oncology Group, and M. D. Anderson Cancer Center Study J Clin Oncol 28 2010 1766 1771
    • (2010) J Clin Oncol , vol.28 , pp. 1766-1771
    • Walter, R.B.1    Kantarjian, H.M.2    Huang, X.3
  • 71
    • 0015721940 scopus 로고
    • Cytosine arabinoside (NSC-63878) and daunorubicin (NSC-83142) therapy in acute nonlymphocytic leukemia
    • JW Yates, HJ Wallace Jr, RR Ellison, JF Holland Cytosine arabinoside (NSC-63878) and daunorubicin (NSC-83142) therapy in acute nonlymphocytic leukemia Cancer Chemother Rep 57 1973 485 488
    • (1973) Cancer Chemother Rep , vol.57 , pp. 485-488
    • Yates, J.W.1    Wallace, Jr.H.J.2    Ellison, R.R.3    Holland, J.F.4
  • 72
    • 0025275742 scopus 로고
    • Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group
    • Z Arlin, DC Case Jr, J Moore et al. Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group Leukemia 4 1990 177 183
    • (1990) Leukemia , vol.4 , pp. 177-183
    • Arlin, Z.1    Case, Jr.D.C.2    Moore, J.3
  • 73
    • 0025907179 scopus 로고
    • Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia
    • E Berman, G Heller, J Santorsa et al. Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia Blood 77 1991 1666 1674
    • (1991) Blood , vol.77 , pp. 1666-1674
    • Berman, E.1    Heller, G.2    Santorsa, J.3
  • 74
    • 0026586008 scopus 로고
    • Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia
    • PH Wiernik, PL Banks, DC Case et al. Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia Blood 79 1992 313 319
    • (1992) Blood , vol.79 , pp. 313-319
    • Wiernik, P.H.1    Banks, P.L.2    Case, D.C.3
  • 75
    • 9044228414 scopus 로고    scopus 로고
    • A randomized study of high-dose cytarabine in induction in acute myeloid leukemia
    • JF Bishop, JP Matthews, GA Young et al. A randomized study of high-dose cytarabine in induction in acute myeloid leukemia Blood 87 1996 1710 1717
    • (1996) Blood , vol.87 , pp. 1710-1717
    • Bishop, J.F.1    Matthews, J.P.2    Young, G.A.3
  • 76
    • 77956400375 scopus 로고    scopus 로고
    • Acute myeloid leukemia or myelodysplastic syndrome in randomized controlled clinical trials of cancer chemotherapy with granulocyte colony-stimulating factor: A systematic review
    • GH Lyman, DC Dale, DA Wolff et al. Acute myeloid leukemia or myelodysplastic syndrome in randomized controlled clinical trials of cancer chemotherapy with granulocyte colony-stimulating factor: a systematic review J Clin Oncol 28 2010 2914 2924
    • (2010) J Clin Oncol , vol.28 , pp. 2914-2924
    • Lyman, G.H.1    Dale, D.C.2    Wolff, D.A.3
  • 77
    • 0035895052 scopus 로고    scopus 로고
    • Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts
    • 15
    • EH Estey, PF Thall, JE Cortes et al. Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts Blood 98 2001 3575 3583 15
    • (2001) Blood , vol.98 , pp. 3575-3583
    • Estey, E.H.1    Thall, P.F.2    Cortes, J.E.3
  • 78
    • 84863435652 scopus 로고    scopus 로고
    • Haematological cancer: The rule of three in AML induction-is cladribine the answer?
    • FR Appelbaum Haematological cancer: The rule of three in AML induction-is cladribine the answer? Nat Rev Clin Oncol 9 2012 376 377
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 376-377
    • Appelbaum, F.R.1
  • 79
    • 84864039689 scopus 로고    scopus 로고
    • Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: A multicenter, randomized phase III study
    • J Holowiecki, S Grosicki, S Giebel et al. Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: a multicenter, randomized phase III study J Clin Oncol 30 2012 2441 2448
    • (2012) J Clin Oncol , vol.30 , pp. 2441-2448
    • Holowiecki, J.1    Grosicki, S.2    Giebel, S.3
  • 80
    • 79952099282 scopus 로고    scopus 로고
    • Identification of patients with acute myeloblastic leukemia who benefit from the addition of gemtuzumab ozogamicin: Results of the MRC AML15 trial
    • AK Burnett, RK Hills, D Milligan et al. Identification of patients with acute myeloblastic leukemia who benefit from the addition of gemtuzumab ozogamicin: results of the MRC AML15 trial J Clin Oncol 29 2011 369 377
    • (2011) J Clin Oncol , vol.29 , pp. 369-377
    • Burnett, A.K.1    Hills, R.K.2    Milligan, D.3
  • 81
    • 84859911350 scopus 로고    scopus 로고
    • Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): A randomised, open-label, phase 3 study
    • S Castaigne, C Pautas, C Terre et al. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study Lancet 379 2012 1508 1516
    • (2012) Lancet , vol.379 , pp. 1508-1516
    • Castaigne, S.1    Pautas, C.2    Terre, C.3
  • 82
    • 84863522871 scopus 로고    scopus 로고
    • Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia
    • AK Burnett, NH Russell, RK Hills et al. Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia J Clin Oncol 30 2012 3924 3943
    • (2012) J Clin Oncol , vol.30 , pp. 3924-3943
    • Burnett, A.K.1    Russell, N.H.2    Hills, R.K.3
  • 83
    • 80052713073 scopus 로고    scopus 로고
    • The clinical development of FLT3 inhibitors in acute myeloid leukemia
    • S Knapper The clinical development of FLT3 inhibitors in acute myeloid leukemia Expert Opin Investig Drugs 20 2011 1377 1395
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 1377-1395
    • Knapper, S.1
  • 84
    • 78650073854 scopus 로고    scopus 로고
    • FLT3 as a therapeutic target in AML: Still challenging after all these years
    • T Kindler, DB Lipka, T Fischer FLT3 as a therapeutic target in AML: still challenging after all these years Blood 116 2010 5089 5102
    • (2010) Blood , vol.116 , pp. 5089-5102
    • Kindler, T.1    Lipka, D.B.2    Fischer, T.3
  • 85
    • 70349467775 scopus 로고    scopus 로고
    • Anthracycline dose intensification in acute myeloid leukemia
    • HF Fernandez, Z Sun, X Yao et al. Anthracycline dose intensification in acute myeloid leukemia N Engl J Med 361 2009 1249 1259
    • (2009) N Engl J Med , vol.361 , pp. 1249-1259
    • Fernandez, H.F.1    Sun, Z.2    Yao, X.3
  • 86
    • 33745003472 scopus 로고    scopus 로고
    • Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia
    • T Buchner, WE Berdel, C Schoch et al. Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia J Clin Oncol 24 2006 2480 2489
    • (2006) J Clin Oncol , vol.24 , pp. 2480-2489
    • Buchner, T.1    Berdel, W.E.2    Schoch, C.3
  • 87
    • 77956455650 scopus 로고    scopus 로고
    • Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: Feasibility, toxicity, and therapeutic results
    • F Ferrara, T Izzo, C Criscuolo, C Riccardi, M Celentano, G Mele Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: feasibility, toxicity, and therapeutic results Am J Hematol 85 2010 687 690
    • (2010) Am J Hematol , vol.85 , pp. 687-690
    • Ferrara, F.1    Izzo, T.2    Criscuolo, C.3    Riccardi, C.4    Celentano, M.5    Mele, G.6
  • 88
    • 40849098011 scopus 로고    scopus 로고
    • Consolidation therapy: What should be the standard of care?
    • JM Rowe Consolidation therapy: what should be the standard of care? Best Pract Res Clin Haematol 21 2008 53 60
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 53-60
    • Rowe, J.M.1
  • 89
    • 0027941369 scopus 로고
    • Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B
    • RJ Mayer, RB Davis, CA Schiffer et al. Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B N Engl J Med 331 1994 896 903
    • (1994) N Engl J Med , vol.331 , pp. 896-903
    • Mayer, R.J.1    Davis, R.B.2    Schiffer, C.A.3
  • 90
    • 17544388046 scopus 로고    scopus 로고
    • Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype
    • CD Bloomfield, D Lawrence, JC Byrd et al. Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype Cancer Res 58 1998 4173 4179
    • (1998) Cancer Res , vol.58 , pp. 4173-4179
    • Bloomfield, C.D.1    Lawrence, D.2    Byrd, J.C.3
  • 91
    • 20944450660 scopus 로고    scopus 로고
    • Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222
    • JO Moore, SL George, RK Dodge et al. Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222 Blood 105 2005 3420 3427
    • (2005) Blood , vol.105 , pp. 3420-3427
    • Moore, J.O.1    George, S.L.2    Dodge, R.K.3
  • 92
    • 84855764294 scopus 로고    scopus 로고
    • New agents for acute myeloid leukemia: Is it time for targeted therapies?
    • F Ferrara New agents for acute myeloid leukemia: is it time for targeted therapies? Expert Opin Investig Drugs 21 2012 179 189
    • (2012) Expert Opin Investig Drugs , vol.21 , pp. 179-189
    • Ferrara, F.1
  • 93
    • 77449155696 scopus 로고    scopus 로고
    • Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: Results of the MRC AML12 trial
    • AK Burnett, RK Hills, DW Milligan et al. Attempts to Optimize Induction and Consolidation Treatment in Acute Myeloid Leukemia: Results of the MRC AML12 Trial J Clin Oncol 28 2010 586 595
    • (2010) J Clin Oncol , vol.28 , pp. 586-595
    • Burnett, A.K.1    Hills, R.K.2    Milligan, D.W.3
  • 94
    • 79960118884 scopus 로고    scopus 로고
    • 2 within first consolidation in acute myeloid leukemia: Results of patients enrolled onto the prospective randomized AML96 study
    • 2 within first consolidation in acute myeloid leukemia: results of patients enrolled onto the prospective randomized AML96 study J Clin Oncol 29 2011 2696 2702
    • (2011) J Clin Oncol , vol.29 , pp. 2696-2702
    • Schaich, M.1    Röllig, C.2    Soucek, S.3
  • 95
    • 0032480930 scopus 로고    scopus 로고
    • Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission
    • PA Cassileth, DP Harrington, FR Appelbaum et al. Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission N Engl J Med 339 1998 1649 1656
    • (1998) N Engl J Med , vol.339 , pp. 1649-1656
    • Cassileth, P.A.1    Harrington, D.P.2    Appelbaum, F.R.3
  • 96
    • 0028889993 scopus 로고
    • Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups
    • RA Zittoun, F Mandelli, R Willemze et al. Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups N Engl J Med 332 1995 217 223
    • (1995) N Engl J Med , vol.332 , pp. 217-223
    • Zittoun, R.A.1    Mandelli, F.2    Willemze, R.3
  • 97
    • 0036036741 scopus 로고    scopus 로고
    • The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: Results of the UK MRC AML 10 trial
    • AK Burnett, K Wheatley, AH Goldstone et al. The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial Br J Haematol 118 2002 385 400
    • (2002) Br J Haematol , vol.118 , pp. 385-400
    • Burnett, A.K.1    Wheatley, K.2    Goldstone, A.H.3
  • 98
    • 78649429727 scopus 로고    scopus 로고
    • Reduced mortality after allogeneic hematopoietic-cell transplantation
    • TA Gooley, JW Chien, SA Pergam et al. Reduced mortality after allogeneic hematopoietic-cell transplantation N Engl J Med 363 2010 2091 2101
    • (2010) N Engl J Med , vol.363 , pp. 2091-2101
    • Gooley, T.A.1    Chien, J.W.2    Pergam, S.A.3
  • 99
    • 84855906869 scopus 로고    scopus 로고
    • Who should be transplanted in first remission of acute myeloid leukaemia?
    • AK Burnett, RK Hills Who should be transplanted in first remission of acute myeloid leukaemia? Curr Treat Options Oncol 12 2011 329 340
    • (2011) Curr Treat Options Oncol , vol.12 , pp. 329-340
    • Burnett, A.K.1    Hills, R.K.2
  • 100
    • 84857622836 scopus 로고    scopus 로고
    • Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: A retrospective analysis
    • S Brunet, M Labopin, J Esteve et al. Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: a retrospective analysis J Clin Oncol 30 2012 735 741
    • (2012) J Clin Oncol , vol.30 , pp. 735-741
    • Brunet, S.1    Labopin, M.2    Esteve, J.3
  • 101
    • 79952757082 scopus 로고    scopus 로고
    • Impact of pretransplantation minimal residual disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation for acute myeloid leukemia
    • RB Walter, TA Gooley, BL Wood et al. Impact of pretransplantation minimal residual disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation for acute myeloid leukemia J Clin Oncol 29 2011 1107 1190
    • (2011) J Clin Oncol , vol.29 , pp. 1107-1190
    • Walter, R.B.1    Gooley, T.A.2    Wood, B.L.3
  • 102
    • 54449098523 scopus 로고    scopus 로고
    • Toward optimization of postremission therapy for residual disease-positive patients with acute myeloid leukemia
    • L Maurillo, F Buccisano, MI Del Principe et al. Toward optimization of postremission therapy for residual disease-positive patients with acute myeloid leukemia J Clin Oncol 26 2008 4944 4951
    • (2008) J Clin Oncol , vol.26 , pp. 4944-4951
    • Maurillo, L.1    Buccisano, F.2    Del Principe, M.I.3
  • 103
    • 80053008957 scopus 로고    scopus 로고
    • Optimizing the conditioning regimen for allogeneic stem-cell transplantation in acute myeloid leukemia; Dose intensity is still in need
    • A Shimoni, A Nagler Optimizing the conditioning regimen for allogeneic stem-cell transplantation in acute myeloid leukemia; dose intensity is still in need Best Pract Res Clin Haematol 24 2011 369 379
    • (2011) Best Pract Res Clin Haematol , vol.24 , pp. 369-379
    • Shimoni, A.1    Nagler, A.2
  • 104
    • 80052973754 scopus 로고    scopus 로고
    • Reduced-intensity conditioning allogeneic hematopoietic cell transplantation in adults with acute myeloid leukemia
    • M Hamadani, M Mohty, MA Kharfan-Dabaja Reduced-intensity conditioning allogeneic hematopoietic cell transplantation in adults with acute myeloid leukemia Cancer Control 18 2011 237 245
    • (2011) Cancer Control , vol.18 , pp. 237-245
    • Hamadani, M.1    Mohty, M.2    Kharfan-Dabaja, M.A.3
  • 105
    • 82955217795 scopus 로고    scopus 로고
    • Autologous peripheral blood stem cell transplantation for acute myeloid leukemia
    • E Vellenga, W van Putten, GJ Ossenkoppele et al. Autologous peripheral blood stem cell transplantation for acute myeloid leukemia Blood 118 2011 6037 6042
    • (2011) Blood , vol.118 , pp. 6037-6042
    • Vellenga, E.1    Van Putten, W.2    Ossenkoppele, G.J.3
  • 106
    • 84856431030 scopus 로고    scopus 로고
    • Prediction of post-remission survival in acute myeloid leukaemia: A post-hoc analysis of the AML96 trial
    • M Pfirrmann, G Ehninger, C Thiede et al. Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trial Lancet Oncol 13 2012 207 214
    • (2012) Lancet Oncol , vol.13 , pp. 207-214
    • Pfirrmann, M.1    Ehninger, G.2    Thiede, C.3
  • 107
    • 79952079063 scopus 로고    scopus 로고
    • Modern approaches to treating acute promyelocytic leukemia
    • MA Sanz, F Lo-Coco Modern approaches to treating acute promyelocytic leukemia J Clin Oncol 29 2011 495 503
    • (2011) J Clin Oncol , vol.29 , pp. 495-503
    • Sanz, M.A.1    Lo-Coco, F.2
  • 108
    • 62549083523 scopus 로고    scopus 로고
    • Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia
    • J Hu, YF Liu, CF Wu et al. Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia Proc Natl Acad Sci USA 106 2009 3307 3342
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 3307-3342
    • Hu, J.1    Liu, Y.F.2    Wu, C.F.3
  • 109
    • 85117738171 scopus 로고    scopus 로고
    • Potential curability of newly diagnosed acute promyelocytic leukemia without use of chemotherapy: The example of liposomal all-trans retinoic acid
    • E Estey, C Koller, AM Tsimberidou et al. Potential curability of newly diagnosed acute promyelocytic leukemia without use of chemotherapy: the example of liposomal all-trans retinoic acid Blood 105 2005 1307 1366
    • (2005) Blood , vol.105 , pp. 1307-1366
    • Estey, E.1    Koller, C.2    Tsimberidou, A.M.3
  • 110
    • 77956251955 scopus 로고    scopus 로고
    • Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Long-term follow-up data
    • V Mathews, B George, E Chendamarai et al. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: long-term follow-up data J Clin Oncol 28 2010 3866 3871
    • (2010) J Clin Oncol , vol.28 , pp. 3866-3871
    • Mathews, V.1    George, B.2    Chendamarai, E.3
  • 111
    • 78649962923 scopus 로고    scopus 로고
    • Has there been progress in the treatment of older patients with acute myeloid leukemia?
    • HP Erba Has there been progress in the treatment of older patients with acute myeloid leukemia? Best Pract Res Clin Haematol 23 2010 495 501
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 495-501
    • Erba, H.P.1
  • 112
    • 78650178860 scopus 로고    scopus 로고
    • Treatment of older patients with acute myeloid leukaemia
    • F Ferrara Treatment of older patients with acute myeloid leukaemia Lancet 376 2010 1967 1968
    • (2010) Lancet , vol.376 , pp. 1967-1968
    • Ferrara, F.1
  • 113
    • 77449121200 scopus 로고    scopus 로고
    • "I am older, not elderly," said the patient with acute myeloid leukemia
    • CA Schiffer "I am older, not elderly," said the patient with acute myeloid leukemia J Clin Oncol 28 2010 521 523
    • (2010) J Clin Oncol , vol.28 , pp. 521-523
    • Schiffer, C.A.1
  • 114
    • 33947205565 scopus 로고    scopus 로고
    • A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment
    • AK Burnett, D Milligan, AG Prentice et al. A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment Cancer 109 2007 1114 1124
    • (2007) Cancer , vol.109 , pp. 1114-1124
    • Burnett, A.K.1    Milligan, D.2    Prentice, A.G.3
  • 115
    • 79953702269 scopus 로고    scopus 로고
    • Treatment of unfit patients with acute myeloid leukemia: A still open clinical challenge
    • F Ferrara Treatment of unfit patients with acute myeloid leukemia: a still open clinical challenge Clin Lymphoma Myeloma Leuk 11 2011 10 16
    • (2011) Clin Lymphoma Myeloma Leuk , vol.11 , pp. 10-16
    • Ferrara, F.1
  • 116
    • 84857747740 scopus 로고    scopus 로고
    • A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy
    • M Lubbert, BH Ruter, R Claus et al. A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy Haematologica 97 2012 393 401
    • (2012) Haematologica , vol.97 , pp. 393-401
    • Lubbert, M.1    Ruter, B.H.2    Claus, R.3
  • 117
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: A randomised, open-label, phase III study
    • P Fenaux, GJ Mufti, E Hellstrom-Lindberg et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study Lancet Oncol 10 2009 223 232
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3
  • 118
    • 84864063679 scopus 로고    scopus 로고
    • Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia
    • HM Kantarjian, XG Thomas, A Dmoszynska et al. Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia J Clin Oncol 30 2012 2670 2676
    • (2012) J Clin Oncol , vol.30 , pp. 2670-2676
    • Kantarjian, H.M.1    Thomas, X.G.2    Dmoszynska, A.3
  • 119
    • 77449149373 scopus 로고    scopus 로고
    • Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
    • P Fenaux, GJ Mufti, E Hellstrom-Lindberg et al. Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia J Clin Oncol 28 2010 562 569
    • (2010) J Clin Oncol , vol.28 , pp. 562-569
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3
  • 120
    • 33846924515 scopus 로고    scopus 로고
    • Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS)
    • E Estey, M de Lima, R Tibes et al. Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) Blood 109 2007 1395 1400
    • (2007) Blood , vol.109 , pp. 1395-1400
    • Estey, E.1    De Lima, M.2    Tibes, R.3
  • 121
    • 3943062139 scopus 로고    scopus 로고
    • Prognostic factors and therapeutic options for relapsed or refractory acute myeloid leukemia
    • F Ferrara, S Palmieri, G Mele Prognostic factors and therapeutic options for relapsed or refractory acute myeloid leukemia Haematologica 89 2004 998 1008
    • (2004) Haematologica , vol.89 , pp. 998-1008
    • Ferrara, F.1    Palmieri, S.2    Mele, G.3
  • 122
    • 0035437132 scopus 로고    scopus 로고
    • Postremission therapy in older patients with de novo acute myeloid leukemia: A randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine
    • RM Stone, DT Berg, SL George et al. Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine Blood 98 2001 548 553
    • (2001) Blood , vol.98 , pp. 548-553
    • Stone, R.M.1    Berg, D.T.2    George, S.L.3
  • 123
    • 34250157761 scopus 로고    scopus 로고
    • Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: Results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial
    • C Gardin, P Turlure, T Fagot et al. Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial Blood 109 2007 5129 5135
    • (2007) Blood , vol.109 , pp. 5129-5135
    • Gardin, C.1    Turlure, P.2    Fagot, T.3
  • 124
    • 56549084042 scopus 로고    scopus 로고
    • What is the impact of hematopoietic cell transplantation (HCT) for older adults with acute myeloid leukemia (AML)?
    • FR Appelbaum What is the impact of hematopoietic cell transplantation (HCT) for older adults with acute myeloid leukemia (AML)? Best Pract Res Clin Haematol 21 2008 667 675
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 667-675
    • Appelbaum, F.R.1
  • 125
    • 33748542276 scopus 로고    scopus 로고
    • Feasibility of autologous peripheral blood stem cell transplantation in elderly patients with acute myeloid leukemia
    • F Ferrara, S Palmieri, M Celentano et al. Feasibility of autologous peripheral blood stem cell transplantation in elderly patients with acute myeloid leukemia Leuk Lymphoma 47 2006 1593 8127
    • (2006) Leuk Lymphoma , vol.47 , pp. 1593-8127
    • Ferrara, F.1    Palmieri, S.2    Celentano, M.3
  • 126
    • 80051941829 scopus 로고    scopus 로고
    • Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: For all, none, or which patients?
    • F Ferrara, P Musto Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: for all, none, or which patients? Cancer 117 2011 3879 3881
    • (2011) Cancer , vol.117 , pp. 3879-3881
    • Ferrara, F.1    Musto, P.2
  • 127
    • 20244361887 scopus 로고    scopus 로고
    • Prognostic index for adult patients with acute myeloid leukemia in first relapse
    • DA Breems, WL Van Putten, PC Huijgens et al. Prognostic index for adult patients with acute myeloid leukemia in first relapse J Clin Oncol 23 2005 1969 1978
    • (2005) J Clin Oncol , vol.23 , pp. 1969-1978
    • Breems, D.A.1    Van Putten, W.L.2    Huijgens, P.C.3
  • 128
    • 84859259613 scopus 로고    scopus 로고
    • Management of refractory acute myeloid leukemia: Re-induction therapy or straight to transplantation?
    • EJ Feldman, U Gergis Management of refractory acute myeloid leukemia: re-induction therapy or straight to transplantation? Curr Hematol Malig Rep 7 2012 74 77
    • (2012) Curr Hematol Malig Rep , vol.7 , pp. 74-77
    • Feldman, E.J.1    Gergis, U.2
  • 129
    • 0023273525 scopus 로고
    • Saturation of 1-beta-D-arabinofuranosylcytosine 5′-triphosphate accumulation in leukemia cells during high-dose 1-beta-D- arabinofuranosylcytosine therapy
    • W Plunkett, JO Liliemark, TM Adams et al. Saturation of 1-beta-D-arabinofuranosylcytosine 5′-triphosphate accumulation in leukemia cells during high-dose 1-beta-D-arabinofuranosylcytosine therapy Cancer Res 47 1987 3005 3011
    • (1987) Cancer Res , vol.47 , pp. 3005-3011
    • Plunkett, W.1    Liliemark, J.O.2    Adams, T.M.3
  • 130
    • 0031005627 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study
    • CP Leith, KJ Kopecky, J Godwin et al. Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study Blood 89 1997 3323 3329
    • (1997) Blood , vol.89 , pp. 3323-3329
    • Leith, C.P.1    Kopecky, K.J.2    Godwin, J.3
  • 131
    • 27144508406 scopus 로고    scopus 로고
    • The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis
    • B van der Holt, B Lowenberg, AK Burnett et al. The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis Blood 106 2005 2646 2654
    • (2005) Blood , vol.106 , pp. 2646-2654
    • Van Der Holt, B.1    Lowenberg, B.2    Burnett, A.K.3
  • 132
    • 0037103189 scopus 로고    scopus 로고
    • Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720
    • MR Baer, SL George, RK Dodge et al. Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720 Blood 100 2002 1224 1232
    • (2002) Blood , vol.100 , pp. 1224-1232
    • Baer, M.R.1    George, S.L.2    Dodge, R.K.3
  • 133
    • 78549238612 scopus 로고    scopus 로고
    • Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: A randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999
    • LD Cripe, H Uno, EM Paietta et al. Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999 Blood 116 2010 4077 4085
    • (2010) Blood , vol.116 , pp. 4077-4085
    • Cripe, L.D.1    Uno, H.2    Paietta, E.M.3
  • 134
    • 77956578835 scopus 로고    scopus 로고
    • P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808
    • Cancer And Leukemia Group B.
    • JE Kolitz, SL George, G Marcucci B Cancer and Leukemia Group P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808 Blood 116 2010 1413 1421
    • (2010) Blood , vol.116 , pp. 1413-1421
    • Kolitz, J.E.1    George, S.L.2    Marcucci, G.3
  • 135
    • 1842457644 scopus 로고    scopus 로고
    • Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: A phase III trial (E2995)
    • PL Greenberg, SJ Lee, R Advani et al. Mitoxantrone, etoposide, and cytarabine with or without valspodar in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome: a phase III trial (E2995) J Clin Oncol 22 2004 1078 1086
    • (2004) J Clin Oncol , vol.22 , pp. 1078-1086
    • Greenberg, P.L.1    Lee, S.J.2    Advani, R.3
  • 136
    • 0027067753 scopus 로고
    • Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase i trial to modulate multidrug resistance
    • BL Lum, S Kaubisch, AM Yahanda et al. Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance J Clin Oncol 10 1992 1635 1642
    • (1992) J Clin Oncol , vol.10 , pp. 1635-1642
    • Lum, B.L.1    Kaubisch, S.2    Yahanda, A.M.3
  • 137
    • 78751703163 scopus 로고    scopus 로고
    • Very late recurrences of leukemia: Why does leukemia awake after many years of dormancy?
    • M Norkin, JP Uberti, CA Schiffer Very late recurrences of leukemia: why does leukemia awake after many years of dormancy? Leuk Res 35 2011 139 144
    • (2011) Leuk Res , vol.35 , pp. 139-144
    • Norkin, M.1    Uberti, J.P.2    Schiffer, C.A.3
  • 138
    • 81055148087 scopus 로고    scopus 로고
    • Regulatory T cells in acute myelogenous leukemia: Is it time for immunomodulation?
    • C Ustun, JS Miller, DH Munn, DJ Weisdorf, BR Blazar Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation? Blood 118 2011 5084 5095
    • (2011) Blood , vol.118 , pp. 5084-5095
    • Ustun, C.1    Miller, J.S.2    Munn, D.H.3    Weisdorf, D.J.4    Blazar, B.R.5
  • 139
    • 33745714215 scopus 로고    scopus 로고
    • Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: Results of a randomized phase 3 trial
    • M Brune, S Castaigne, J Catalano et al. Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial Blood 108 2006 88 96
    • (2006) Blood , vol.108 , pp. 88-96
    • Brune, M.1    Castaigne, S.2    Catalano, J.3
  • 140
    • 54449095992 scopus 로고    scopus 로고
    • Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and leukemia group B study 9720
    • MR Baer, SL George, MA Caligiuri et al. Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: cancer and leukemia group B study 9720 J Clin Oncol 26 2008 4934 4939
    • (2008) J Clin Oncol , vol.26 , pp. 4934-4939
    • Baer, M.R.1    George, S.L.2    Caligiuri, M.A.3


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