New insights into aldosterone-producing adenomas and hereditary aldosteronism: Mutations in the K+ channel KCNJ5

Current Opinion in Nephrology and Hypertension

Volumn 22, Issue 2, 2013, Pages 141-147

  Scholl, Ute I ^a   Lifton, Richard P ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endocrine tumor; exome sequencing; hypertension; Kir3.4; somatic mutation

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL KCNJ5; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ADRENAL HYPERPLASIA; ALDOSTERONE RELEASE; AUTOSOMAL DOMINANT INHERITANCE; CALCIUM TRANSPORT; CELL PROLIFERATION; DISEASE CLASSIFICATION; GAIN OF FUNCTION MUTATION; GENE; GENETIC DISORDER; GERM LINE; HETEROZYGOSITY; HUMAN; HYPERALDOSTERONISM; KCNJ5 GENE; LETHALITY; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; NONHUMAN; PATHOGENESIS; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; REVIEW; SODIUM CONDUCTANCE; SOMATIC MUTATION;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ANIMALS; CALCIUM; CALCIUM CHANNELS; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; HYPERALDOSTERONISM; ION CHANNEL GATING; MALE; MUTATION; PHENOTYPE; POTASSIUM; SODIUM;

EID: 84873567626     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32835cecf8     Document Type: Review

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