Mast cells act as phagocytes against the periodontopathogen aggregatibacter actinomycetemcomitans

Journal of Periodontology

Volumn 84, Issue 2, 2013, Pages 265-272

  Lima, Heliton G ^a   Pinke, Karen H ^a   Gardizani, Taiane P ^a   Devandir A Souza Junior ^a   Carlos, Daniela ^a   Mario J Avila Campos, ^a   Lara, Vanessa S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Gram negative bacteria; Macrophages; Mast cells; Periodontal disease; Phagocytosis

Indexed keywords

ACRIDINE ORANGE; DIAGNOSTIC AGENT; FLUORESCENT DYE;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ANIMAL; ARTICLE; BACTERIAL LOAD; BIOFILM; BONE MARROW CELL; C57BL MOUSE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CULTURE TECHNIQUE; ESCHERICHIA COLI; HUMAN; IMMUNOLOGY; MACROPHAGE; MALE; MAST CELL; MICROBIOLOGY; MOUSE; PERIODONTAL DISEASE; PHAGOCYTE; PHAGOCYTOSIS; TIME;

ACRIDINE ORANGE; ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ANIMALS; BACTERIAL LOAD; BIOFILMS; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; ESCHERICHIA COLI; FLUORESCENT DYES; HUMANS; MACROPHAGES; MALE; MAST CELLS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; PERIODONTAL DISEASES; PHAGOCYTES; PHAGOCYTOSIS; TIME FACTORS;

EID: 84873543949     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2012.120087     Document Type: Article

References (50)

1. Aberg CH, Sjödin B, Lakio L, Pussinen PJ, Johansson A, Claesson R. Presence of Aggregatibacter actinomycetemcomitans in young individuals: A 16-year clinical and microbiological follow-up study. J Clin Periodontol 2009;36:815-822.
2. Faveri M, Figueiredo LC, Duarte PM, Mestnik MJ, Mayer MP, Feres M. Microbiological profile of untreated subjects with localized aggressive periodontitis. J Clin Periodontol 2009;36:739-749.
3. Berezow AB, Darveau RP. Microbial shift and periodontitis. Periodontol 2000 2011;55:36-47.
4. van Winkelhoff AJ, Slots J. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in nonoral infections. Periodontol 2000 1999;20:122-135.
5. Henderson B, Nair SP, Ward JM, Wilson M. Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. Annu Rev Microbiol 2003;57:29-55.
6. Henderson B, Ward JM, Ready D. Aggregatibacter (Actinobacillus) actinomycetemcomitans: A triple A periodontopathogen? Periodontol 2000 2010;54:78-105.
7. Kinane DF, Attström R; European Workshop in Periodontology group B. Advances in the pathogenesis of periodontitis. Group B consensus report of the fifth European Workshop in Periodontology. J Clin Periodontol 2005;32(Suppl. 6):130-131.
8. Graves D. Cytokines that promote periodontal tissue destruction. J Periodontol 2008;79(Suppl. 8):1585-1591.
9. Liu YC, Lerner UH, Teng YT. Cytokine responses against periodontal infection: protective and destructive roles. Periodontol 2000 2010;52:163-206.
10. Garlet GP, Cardoso CR, Campanelli AP, et al. The dual role of p55 tumour necrosis factor-alpha receptor in Actinobacillus actinomycetemcomitans-induced experimental periodontitis: Host protection and tissue destruction. Clin Exp Immunol 2007;147:128-138.
11. Trombone AP, Ferreira SB Jr, Raimundo FM, et al. Experimental periodontitis in mice selected for maximal or minimal inflammatory reactions: Increased inflammatory immune responsiveness drives increased alveolar bone loss without enhancing the control of periodontal infection. J Periodontal Res 2009;44:443-451.
12. Steinsvoll S, Helgeland K, Schenck K. Mast cells - A role in periodontal diseases? J Clin Periodontol 2004; 31:413-419.
13. Batista AC, Rodini CO, Lara VS. Quantification of mast cells in different stages of human periodontal disease. Oral Dis 2005;11:249-254.
14. Taylor ML, Metcalfe DD. Mast cells in allergy and host defense. Allergy Asthma Proc 2001;22:115-119.
15. Arzi B, Murphy B, Cox DP, Vapniarsky N, Kass PH, Verstraete FJ. Presence and quantification of mast cells in the gingiva of cats with tooth resorption, periodontitis and chronic stomatitis. Arch Oral Biol 2010;55:148-154.
16. Mekori YA, Metcalfe DD. Mast cells in innate immunity. Immunol Rev 2000;173:131-140.
17. von Köckritz-Blickwede M, Goldmann O, Thulin P, et al. Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation. Blood 2008;111:3070-3080.
18. Malaviya R, Ross EA, MacGregor JI, et al. Mast cell phagocytosis of FimH-expressing enterobacteria. J Immunol 1994;152:1907-1914.
19. Malaviya R, Twesten NJ, Ross EA, Abraham SN, Pfeifer JD. Mast cells process bacterial Ags through a phagocytic route for class I MHC presentation to T cells. J Immunol 1996;156:1490-1496.
20. Shin JS, Gao Z, Abraham SN. Involvement of cellular caveolae in bacterial entry into mast cells. Science 2000;289:785-788.
21. Malaviya R, Abraham SN. Mast cell modulation of immune responses to bacteria. Immunol Rev 2001; 179:16-24.
22. Rönnberg E, Guss B, Pejler G. Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response. Infect Immun 2010;78:854-864.
23. Abel J, Goldmann O, Ziegler C, et al. Staphylococcus aureus evades the extracellular antimicrobial activity of mast cells by promoting its own uptake. J Innate Immun 2011;3:495-507.
24. Jamur MC, Grodzki AC, Berenstein EH, Hamawy MM, Siraganian RP, Oliver C. Identification and characterization of undifferentiated mast cells in mouse bone marrow. Blood 2005;105:4282-4289.
25. Basciano LK, Berenstein EH, Kmak L, Siraganian RP. Monoclonal antibodies that inhibit IgE binding. J Biol Chem 1986;261:11823-11831.
26. Guo NH, Her GR, Reinhold VN, Brennan MJ, Siraganian RP, Ginsburg V. Monoclonal antibody AA4, which inhibits binding of IgE to high affinity receptors on rat basophilic leukemia cells, binds to novel alpha-galactosyl derivatives of ganglioside GD1b. J Biol Chem 1989;264:13267-13272.
27. Gasparoto TH, Vieira NA, Porto VC, Campanelli AP, Lara VS. Ageing exacerbates damage of systemic and salivary neutrophils from patients presenting Candidarelated denture stomatitis. Immun Ageing 2009;6:3.
28. Murciano C, Yáñez A, O'Connor JE, Gozalbo D, Gil ML. Influence of aging on murine neutrophil and macrophage function against Candida albicans. FEMS Immunol Med Microbiol 2008;53:214-221.
29. Marshall JS. Mast-cell responses to pathogens. Nat Rev Immunol 2004;4:787-799.
30. Dawicki W, Marshall JS. New and emerging roles for mast cells in host defence. Curr Opin Immunol 2007; 19:31-38.
31. Chen K, Xiang Y, Yao X, et al. The active contribution of Toll-like receptors to allergic airway inflammation. Int Immunopharmacol 2011;11:1391-1398.
32. Abbas AK, Lichtman AH, Pillai S. Antibodies and antigens. In: Cellular and Molecular Immunology. Philadelphia: Saunders/Elsevier; 2010:75-96.
33. Sher A, McIntyre SL. Receptors for C3 on rat peritoneal mast cells. J Immunol 1977;119:722-725.
34. Abraham SN, Malaviya R. Mast cells in infection and immunity. Infect Immun 1997;65:3501-3508.
35. Malaviya R, Gao Z, Thankavel K, van der Merwe PA, Abraham SN. The mast cell tumor necrosis factor alpha response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48. Proc Natl Acad Sci USA 1999;96:8110-8115.
36. Marshall JS, Jawdat DM. Mast cells in innate immunity. J Allergy Clin Immunol 2004;114:21-27.
37. Stassen M, Müller C, Arnold M, et al. IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF kappa B is decisively involved in the expression of IL-9. J Immunol 2001;166:4391-4398.
38. Supajatura V, Ushio H, Nakao A, Okumura K, Ra C, Ogawa H. Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4. J Immunol 2001;167:2250-2256.
39. Gelani V, Fernandes AP, Gasparoto TH, et al. The role of toll-like receptor 2 in the recognition of Aggregatibacter actinomycetemcomitans. J Periodontol 2009; 80:2010-2019.
40. Applequist SE, Wallin RP, Ljunggren HG. Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines. Int Immunol 2002;14: 1065-1074.
41. Carlos D, Frantz FG, Souza-Júnior DA, et al. TLR2- dependent mast cell activation contributes to the control of mycobacterium tuberculosis infection. Microbes Infect 2009;11:770-778.
42. Drevets DA, Leenen PJ, Campbell PA. Complement receptor type 3 (CD11b/CD18) involvement is essential for killing of Listeria monocytogenes by mouse macrophages. J Immunol 1993;151:5431-5439.
43. Warren J, Mastroeni P, Dougan G, et al. Increased susceptibility of C1q-deficient mice to Salmonella enterica serovar Typhimurium infection. Infect Immun 2002;70:551-557.
44. Geier H, Celli J. Phagocytic receptors dictate phagosomal escape and intracellular proliferation of Francisella tularensis. Infect Immun 2011;79:2204-2214.
45. Féger F, Varadaradjalou S, Gao Z, Abraham SN, Arock M. The role of mast cells in host defense and their subversion by bacterial pathogens. Trends Immunol 2002;23:151-158.
46. Shin JS, Abraham SN. Co-option of endocytic functions of cellular caveolae by pathogens. Immunology 2001;102:2-7.
47. Prodeus AP, Zhou X, Maurer M, Galli SJ, Carroll MC. Impaired mast cell-dependent natural immunity in complement C3-deficient mice. Nature 1997;390: 172-175.
48. Malaviya R, Ikeda T, Ross E, Abraham SN. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha. Nature 1996; 381:77-80.
49. Arock M, Ross E, Lai-Kuen R, Averlant G, Gao Z, Abraham SN. Phagocytic and tumor necrosis factor alpha response of human mast cells following exposure to gram-negative and gram-positive bacteria. Infect Immun 1998;66:6030-6034.
50. Malaviya R, Abraham SN. Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis. J Leukoc Biol 2000;67: 841-846.