The histamine H3-receptor inverse agonist Pitolisant improves fear memory in mice

Behavioural Brain Research

Volumn 243, Issue 1, 2013, Pages 199-204

  Brabant, Christian ^a   Charlier, Yana ^a   Tirelli, Ezio ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Consolidation; Fear conditioning; Histamine; Memory; Mice; Pitolisant; Reconsolidation

Indexed keywords

BF 2649; DIZOCILPINE; HISTAMINE H3 RECEPTOR AGONIST; PITOLISANT; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL TEST; FEAR; FEAR CONDITIONING TASK; FEMALE; MEMORY; MEMORY CONSOLIDATION; MEMORY RECONSOLIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; PSYCHOPHARMACOTHERAPY; TASK PERFORMANCE; TREATMENT OUTCOME;

ANIMALS; BEHAVIOR, ANIMAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FEAR; FEMALE; HISTAMINE AGONISTS; MEMORY; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; PIPERIDINES;

EID: 84873519490     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.12.063     Document Type: Article

References (43)

1. 3 receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients. Neurobiology of Disease 2008, 30:74-83.
2. 3 receptor: an alternative stimulant for narcolepsy cataplexy in teenagers with refractory sleepiness. Clinical Pharmacology 2012, 35:55-60.
3. 3 receptor: preclinical pharmacology. Journal of Pharmacology and Experimental Therapeutics 2007, 320:365-375.
4. Tiligada E., Kyriakidis K., Chazot P.L., Passani M.B. Histamine pharmacology and new CNS drug targets. CNS Neuroscience and Therapeutics 2011, 17:620-628.
5. Sacchetti B., Ambrogi-Lorenzini C., Baldi E., Tassoni G., Bucherelli C. Auditory thalamus, dorsal hippocampus, basolateral amygdala, and perirhinal cortex role in the consolidation of conditioned freezing to context and to acoustic conditioned stimulus in the rat. Journal of Neuroscience 1999, 19:9570-9578.
6. Baldi E., Mariottini C., Bucherelli C. The role of the nucleus basalis magnocellularis in fear conditioning consolidation in the rat. Learning and Memory 2007, 14:855-860.
7. Haas H.L., Sergeeva O.A., Selbach O. Histamine in the nervous system. Physiological Reviews 2008, 88:1183-1241.
8. 4 receptor is functionally expressed on neurons in the mammalian CNS. British Journal of Pharmacology 2009, 157:55-63.
9. 3) of histamine receptor. Nature 1983, 302:832-837.
10. Benarroch E.E. Histamine in the CNS: multiple functions and potential neurologic implications. Neurology 2010, 75:1472-1479.
11. Köhler C.A., da Silva W.C., Benetti F., Bonini J.S. Histaminergic mechanisms for modulation of memory systems. Neural Plasticity 2011, 328602.
12. McGaugh J.L., Roozendaal B. Drug enhancement of memory consolidation: historical perspective and neurobiological implications. Psychopharmacology 2009, 202:3-14.
13. Bohbot V., Otáhal P., Liu Z., Nadel L., Bures J. Electroconvulsive shock and lidocaine reveal rapid consolidation of spatial working memory in the water maze. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:4016-4019.
14. 3 receptor inverse agonist thioperamide, given alone or in combination with the N-methyl-d-aspartate receptor antagonist dizocilpine, on reconsolidation and consolidation of a contextual fear memory in mice. Neuroscience 2011, 193:132-142.
15. Camera K., Mello C.F., Ceretta A.P., Rubin M.A. Systemic administration of polyaminergic agents modulate fear conditioning in rats. Psychopharmacology 2007, 192:457-464.
16. de Almeida M.A., Izquierdo I. Memory facilitation by histamine. Archives Internationales de Pharmacodynamie et de Therapie 1986, 283:193-198.
17. 3 antagonist thioperamide dose-dependently enhances memory consolidation and reverses amnesia induced by dizocilpine or scopolamine in a one-trial inhibitory avoidance task in mice. Behavioural Brain Research 2004, 154:211-219.
18. 3 receptor antagonists A-304120 and A-317920. II. In vivo behavioural and neurophysiological characterization. Journal of Pharmacology and Experimental Therapeutics 2003, 305:897-908.
19. 3 receptor antagonist. Journal of Pharmacology and Experimental Therapeutics 2005, 313:176-190.
20. 3-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task. Behavioural Brain Research 2001, 124:235-242.
21. Nadel L., Hupbach A., Gomez R., Newman-Smith K. Memory formation, consolidation and transformation. Neuroscience and Biobehavioral Reviews 2012, 36:1640-1645.
22. Przybyslawski J., Sara S.J. Reconsolidation of memory after its reactivation. Behavioural Brain Research 1997, 84:241-246.
23. Suzuki A., Josselyn S.A., Frankland P.W., Masushige S., Silva A.J., Kida S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. Journal of Neuroscience 2004, 24:4787-4795.
24. Nader K., Schafe G.E., Le Doux J.E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 2000, 406:722-726.
25. Milton A.L., Lee J.L., Butler V.J., Gardner R., Everitt B.J. Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors. Journal of Neuroscience 2008, 28:8230-8237.
26. Lee J.L., Milton A.L., Everitt B.J. Reconsolidation and extinction of conditioned fear: inhibition and potentiation. Journal of Neuroscience 2006, 26:10051-10056.
27. Milton A.L., Lee J.L., Everitt B.J. Reconsolidation of appetitive memories for both natural and drug reinforcement is dependent on {beta}-adrenergic receptors. Learning and Memory 2008, 15:88-92.
28. De{ogonek}biec J., Bush D.E., LeDoux J.E. Noradrenergic enhancement of reconsolidation in the amygdala impairs extinction of conditioned fear in rats - a possible mechanism for the persistence of traumatic memories in PTSD. Depression and Anxiety 2011, 28:186-193.
29. Bustos S.G., Maldonado H., Molina V.A. Midazolam disrupts fear memory reconsolidation. Neuroscience 2006, 139:831-842.
30. LeDoux J.E. Emotion circuits in the brain. Annual Review of Neuroscience 2000, 23:155-184.
31. Lee J.L., Everitt B.J., Thomas K.L. Independent cellular processes for hippocampal memory consolidation and reconsolidation. Science 2004, 304:839-843.
32. 3 receptor-mediated impairment of contextual fear conditioning and in vivo inhibition of cholinergic transmission in the rat basolateral amygdala. European Journal of Neuroscience 2001, 14:1522-1532.
33. 3 receptors in the rat basolateral amygdala improves expression of fear memory and enhances acetylcholine release. European Journal of Neuroscience 2002, 16:521-528.
34. Giovannini M.G., Efoudebe M., Passani M.B., Baldi E., Bucherelli C., Giachi F., et al. Improvement in fear memory by histamine-elicited ERK2 activation in hippocampal CA3 cells. Journal of Neuroscience 2003, 23:9016-9023.
35. Knox D., Berntson G.G. Effect of nucleus basalis magnocellularis cholinergic lesions on fear-like and anxiety-like behavior. Behavioral Neuroscience 2006, 120:307-312.
36. Benetti F., Baldi E., Bucherelli C., Blandina P., Passani M.B. Histaminergic ligands injected into the nucleus basalis magnocellularis differentially affect fear conditioning consolidation. International Journal of Neuropsychopharmacology 2012, 15:1-8.
37. Giannoni P., Passani M.B., Nosi D., Chazot P., Shenton F., Mehurst A., et al. Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat. European Journal of Neuroscience 2009, 29:2363-2374.
38. Barnes P., Kirtley A., Thomas K.L. Quantitatively and qualitatively different cellular processes are engaged in CA1 during the consolidation and reconsolidation of contextual fear memory. Hippocampus 2012, 22:149-171.
39. Bucherelli C., Baldi E., Mariottini C., Passani M.B., Blandina P. Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation. Learning and Memory 2006, 13:426-430.
40. Burban A., Faucard R., Armand V., Bayard C., Vorobjev V., Arrang J.M. Histamine potentiates N-methyl-d-aspartate receptors by interacting with an allosteric site distinct from the polyamine binding site. Journal of Pharmacology and Experimental Therapeutics 2010, 332:912-921.
41. Vorobjev V.S., Sharonova I.N., Walsh I.B., Haas H.L. Histamine potentiates N-methyl-d-aspartate responses in acutely isolated hippocampal neurons. Neuron 1993, 11:837-844.
42. Xu L.S., Yang L.X., Hu W.W., Yu X., Ma L., Liu L.Y., et al. Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats. Acta Pharmacologica Sinica 2005, 26:1448-1453.
43. 3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives. British Journal of Pharmacology 2012, 167:1398-1414.