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Volumn 18, Issue 1, 2013, Pages 50-55

Iron-chelation therapy with oral chelators in patients with thalassemia major

Author keywords

Oral chelator; Side effects; Splenectomy; Thalassaemia major

Indexed keywords

CHELATING AGENT; DEFERASIROX; DEFERIPRONE; FERRITIN;

EID: 84873519235     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/1607845412Y.0000000046     Document Type: Article
Times cited : (12)

References (27)
  • 1
    • 33645525914 scopus 로고    scopus 로고
    • Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins
    • Wintrobe MM, Greer JP. Wintrobe's clinical hematology. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2009. pp. 1099-100.
    • (2009) Wintrobe's Clinical Hematology , pp. 1099-1100
    • Wintrobe, M.M.1    Greer, J.P.2
  • 2
    • 77955915545 scopus 로고    scopus 로고
    • Pathogenesis and management of iron toxicity in thalassemia
    • Hershko C. Pathogenesis and management of iron toxicity in thalassemia. Ann N Y Acad Sci. 2010;1202:1-9.
    • (2010) Ann N Y Acad Sci , vol.1202 , pp. 1-9
    • Hershko, C.1
  • 5
    • 84859163314 scopus 로고    scopus 로고
    • Iron chelation therapy in thalassemia syndromes
    • Cianciulli P. Iron chelation therapy in thalassemia syndromes. Mediterr J Hematol Infect Dis. 2009;1:e2009034.
    • (2009) Mediterr J Hematol Infect Dis , vol.1
    • Cianciulli, P.1
  • 7
    • 0032954376 scopus 로고    scopus 로고
    • Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry
    • Fischer R, Tiemann CD, Engelhardt R, Nielsen P, Durken M, Gabbe EE, et al. Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry. Am J Hematol. 1999;60:289-99.
    • (1999) Am J Hematol , vol.60 , pp. 289-299
    • Fischer, R.1    Tiemann, C.D.2    Engelhardt, R.3    Nielsen, P.4    Durken, M.5    Gabbe, E.E.6
  • 9
    • 36448937511 scopus 로고    scopus 로고
    • Deferiprone in the treatment of transfusion-dependent thalassemia: A review and perspective
    • Galanello R. Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective. Ther Clin Risk Manag. 2007;3:795-805.
    • (2007) Ther Clin Risk Manag , vol.3 , pp. 795-805
    • Galanello, R.1
  • 10
    • 39349086377 scopus 로고    scopus 로고
    • Ethical issues and risk/benefit assessment of iron chelation therapy: Advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox
    • Kontoghiorghes GJ. Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox. Hemoglobin 2008;32:1-15.
    • (2008) Hemoglobin , vol.32 , pp. 1-15
    • Kontoghiorghes, G.J.1
  • 11
    • 33745774771 scopus 로고    scopus 로고
    • Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload
    • Piga A, Galanello R, Forni GL, Cappellini MD, Origa R, Zappu A, et al. Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload. Haematologica 2006;91: 873-80.
    • (2006) Haematologica , vol.91 , pp. 873-880
    • Piga, A.1    Galanello, R.2    Forni, G.L.3    Cappellini, M.D.4    Origa, R.5    Zappu, A.6
  • 12
    • 18444390877 scopus 로고    scopus 로고
    • Deferiprone versus deferoxamine in patients with thalassemia major: A randomized clinical trial
    • Maggio A, D'Amico G, Morabito A, Capra M, Ciaccio C, Cianciulli P, et al. Deferiprone versus deferoxamine in patients with thalassemia major: a randomized clinical trial. Blood Cells Mol Dis. 2002;28:196-208.
    • (2002) Blood Cells Mol Dis , vol.28 , pp. 196-208
    • Maggio, A.1    D'amico, G.2    Morabito, A.3    Capra, M.4    Ciaccio, C.5    Cianciulli, P.6
  • 14
    • 77950682176 scopus 로고    scopus 로고
    • Tailoring iron chelation by iron intake and serum ferritin: The prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias
    • Cappellini MD, Porter J, El-Beshlawy A, Li CK, Seymour JF, Elalfy M, et al. Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias. Haematologica 2010;95:557-66.
    • (2010) Haematologica , vol.95 , pp. 557-566
    • Cappellini, M.D.1    Porter, J.2    El-Beshlawy, A.3    Li, C.K.4    Seymour, J.F.5    Elalfy, M.6
  • 15
    • 79961008228 scopus 로고    scopus 로고
    • Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: Efficacy and safety during 5 years' follow-up
    • Cappellini MD, Bejaoui M, Agaoglu L, Canatan D, Capra M, Cohen A, et al. Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up. Blood 2011;118:884-93.
    • (2011) Blood , vol.118 , pp. 884-893
    • Cappellini, M.D.1    Bejaoui, M.2    Agaoglu, L.3    Canatan, D.4    Capra, M.5    Cohen, A.6
  • 16
    • 0024310392 scopus 로고
    • Desferrioxamine ototoxicity: Evaluation of risk factors in thalassaemic patients and guidelines for safe dosage
    • Porter JB, Jaswon MS, Huehns ER, East CA, Hazell JW. Desferrioxamine ototoxicity: evaluation of risk factors in thalassaemic patients and guidelines for safe dosage. Br J Haematol. 1989;73:403-9.
    • (1989) Br J Haematol , vol.73 , pp. 403-409
    • Porter, J.B.1    Jaswon, M.S.2    Huehns, E.R.3    East, C.A.4    Hazell, J.W.5
  • 17
    • 70449403619 scopus 로고    scopus 로고
    • Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusiondependent anaemia and iron overload
    • Taher A, Cappellini MD, Vichinsky E, Galanello R, Piga A, Lawniczek T, et al. Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusiondependent anaemia and iron overload. Br J Haematol. 2009; 147:752-9.
    • (2009) Br J Haematol , vol.147 , pp. 752-759
    • Taher, A.1    Cappellini, M.D.2    Vichinsky, E.3    Galanello, R.4    Piga, A.5    Lawniczek, T.6
  • 18
    • 84864932660 scopus 로고    scopus 로고
    • Cardiac iron removal and functional cardiac improvement by different iron chelation regimens in thalassemia major patients
    • Cassinerio E, Roghi A, Pedrotti P, Brevi F, Zanaboni L, Graziadei G, et al. Cardiac iron removal and functional cardiac improvement by different iron chelation regimens in thalassemia major patients. AnnHematol.2012;91(9):1443-9.
    • (2012) AnnHematol , vol.91 , Issue.9 , pp. 1443-1449
    • Cassinerio, E.1    Roghi, A.2    Pedrotti, P.3    Brevi, F.4    Zanaboni, L.5    Graziadei, G.6
  • 19
    • 79957497558 scopus 로고    scopus 로고
    • Efficacy, compliance and toxicity factors are affecting the rate of normalization of body iron stores in thalassemia patients using the deferiprone and deferoxamine combination therapy
    • Kolnagou A, Kleanthous M, Kontoghiorghes GJ. Efficacy, compliance and toxicity factors are affecting the rate of normalization of body iron stores in thalassemia patients using the deferiprone and deferoxamine combination therapy. Hemoglobin 2011;35:186-98.
    • (2011) Hemoglobin , vol.35 , pp. 186-198
    • Kolnagou, A.1    Kleanthous, M.2    Kontoghiorghes, G.J.3
  • 20
    • 84863376394 scopus 로고    scopus 로고
    • Chelation use and iron burden in North American and British thalassemia patients: A report from the Thalassemia Longitudinal Cohort
    • Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, et al. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood 2012;119: 2746-53.
    • (2012) Blood , vol.119 , pp. 2746-2753
    • Kwiatkowski, J.L.1    Kim, H.Y.2    Thompson, A.A.3    Quinn, C.T.4    Mueller, B.U.5    Odame, I.6
  • 22
    • 38349157810 scopus 로고    scopus 로고
    • Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major
    • Cohen AR, Glimm E, Porter JB. Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major. Blood 2008;111:583-7.
    • (2008) Blood , vol.111 , pp. 583-587
    • Cohen, A.R.1    Glimm, E.2    Porter, J.B.3
  • 23
    • 57349185625 scopus 로고    scopus 로고
    • Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats
    • Bruin GJ, Faller T, Wiegand H, Schweitzer A, Nick H, Schneider J, et al. Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug Metab Dispos. 2008;36:2523-38.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2523-2538
    • Bruin, G.J.1    Faller, T.2    Wiegand, H.3    Schweitzer, A.4    Nick, H.5    Schneider, J.6
  • 24
    • 34248567047 scopus 로고    scopus 로고
    • Deferasirox: Uncertain future following renal failure fatalities, agranulocytosis and other toxicities
    • Kontoghiorghes GJ. Deferasirox: uncertain future following renal failure fatalities, agranulocytosis and other toxicities. Expert Opin Drug Saf. 2007;6:235-9.
    • (2007) Expert Opin Drug Saf , vol.6 , pp. 235-239
    • Kontoghiorghes, G.J.1
  • 25
    • 0026519768 scopus 로고
    • Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones
    • Singh S, Epemolu RO, Dobbin PS, Tilbrook GS, Ellis BL, Damani LA, et al. Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones. Drug Metab Dispos. 1992;20:256-61.
    • (1992) Drug Metab Dispos , vol.20 , pp. 256-261
    • Singh, S.1    Epemolu, R.O.2    Dobbin, P.S.3    Tilbrook, G.S.4    Ellis, B.L.5    Damani, L.A.6
  • 27
    • 0031836302 scopus 로고    scopus 로고
    • Classification and diagnosis of iron overload
    • Piperno A. Classification and diagnosis of iron overload. Haematologica 1998;83:447-55.
    • (1998) Haematologica , vol.83 , pp. 447-455
    • Piperno, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.