-
1
-
-
33745531237
-
Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac iron and the prevention of heart disease in thalassemia. The protocol of the International Committee on Oral Chelators
-
DOI 10.1080/03630260600642567, PII T532567X03X767
-
Kolnagou A, Kontoghiorghes GJ. Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac iron and the prevention of heart disease in thalassemia. The protocol of the International Committee on Oral Chelators. Hemoglobin. 2006;30(2): 239-249 (Pubitemid 43977326)
-
(2006)
Hemoglobin
, vol.30
, Issue.2
, pp. 239-249
-
-
Kolnagou, A.1
Kontoghiorghes, G.2
-
2
-
-
39349096186
-
Long term comparative studies in thalassemia patients treated with deferoxamine or a deferoxamine/deferiprone combination. Identification of effective chelation therapy protocols
-
DOI 10.1080/03630260701727085, PII 790612325
-
Kolnagou A, Economides Ch, Eracleous E, Kontoghiorghes GJ. Long term comparative studies in thalassemia patients treated with deferoxamine or deferoxamine/deferiprone combination. Identification of effective chelation therapy protocols. Hemoglobin. 2008;32(1-2): 41-47 (Pubitemid 351264511)
-
(2008)
Hemoglobin
, vol.32
, Issue.1-2
, pp. 41-47
-
-
Kolnagou, A.1
Economides, C.2
Eracleous, E.3
Kontoghiorghes, G.J.4
-
3
-
-
78049273304
-
Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy
-
Kolnagou A, Kleanthous M, Kontoghiorghes GJ. Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/ deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. Eur J Haematol. 2010;85(5): 430-438
-
(2010)
Eur. J. Haematol.
, vol.85
, Issue.5
, pp. 430-438
-
-
Kolnagou, A.1
Kleanthous, M.2
Kontoghiorghes, G.J.3
-
4
-
-
74049116227
-
Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major
-
Farmaki K, Tzoumari I, Pappa C, Chouliaras G, Berdoukas V. Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major. Br J Haematol. 2010;148(3): 466-475
-
(2010)
Br. J. Haematol.
, vol.148
, Issue.3
, pp. 466-475
-
-
Farmaki, K.1
Tzoumari, I.2
Pappa, C.3
Chouliaras, G.4
Berdoukas, V.5
-
5
-
-
77953759472
-
New golden era of chelation therapy in thalassaemia: The achievement and maintenance of normal range body iron stores
-
Kolnagou A, Kontoghiorghes GJ. New golden era of chelation therapy in thalassaemia: the achievement and maintenance of normal range body iron stores. Br J Haematol. 2010;150(4): 489-490
-
(2010)
Br. J. Haematol.
, vol.150
, Issue.4
, pp. 489-490
-
-
Kolnagou, A.1
Kontoghiorghes, G.J.2
-
6
-
-
39349091615
-
Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalassemia. Complete reversal of the cardiomyopathy and normalization of iron load by deferiprone
-
DOI 10.1080/03630260701726491, PII 790613078
-
Kolnagou A, Michaelides Y, Kontos C, Kyriacou K, Kontoghiorghes GJ. Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalassemia. Complete reversal of the cardiomyopathy and normalization of iron load by deferiprone. Hemoglobin. 2008;32(1-2): 17-28 (Pubitemid 351264514)
-
(2008)
Hemoglobin
, vol.32
, Issue.1-2
, pp. 17-28
-
-
Kolnagou, A.1
Michaelides, Y.2
Kontos, C.3
Kyriacou, K.4
Kontoghiorghes, G.J.5
-
7
-
-
77953249366
-
Maintenance of normal range body iron store levels for up to 45 years in thalassemia major patients using deferiprone monotherapy
-
Kolnagou A, Kontoghiorghes GJ. Maintenance of normal range body iron store levels for up to 45 years in thalassemia major patients using deferiprone monotherapy. Hemoglobin. 2010;34(3): 204-209
-
(2010)
Hemoglobin.
, vol.34
, Issue.3
, pp. 204-209
-
-
Kolnagou, A.1
Kontoghiorghes, G.J.2
-
8
-
-
18044399191
-
Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
-
DOI 10.1053/euhj.2001.2822
-
Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001;22(23): 2171-2179 (Pubitemid 33139463)
-
(2001)
European Heart Journal
, vol.22
, Issue.23
, pp. 2171-2179
-
-
Anderson, L.J.1
Holden, S.2
Davis, B.3
Prescott, E.4
Charrier, C.C.5
Bunce, N.H.6
Firmin, D.N.7
Wonke, B.8
Porter, J.9
Walker, J.M.10
Pennell, D.J.11
-
9
-
-
1442307460
-
Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease
-
DOI 10.1182/blood-2003-06-1919
-
Wood JC, Tyszka JM, Carson S, Nelson MD, Coates TD. Myocardial iron loading in transfusion dependent thalassemia and sickle cell disease. Blood. 2004;103(5): 1934-1936 (Pubitemid 38268994)
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1934-1936
-
-
Wood, J.C.1
Tyszka, J.M.2
Carson, S.3
Nelson, M.D.4
Coates, T.D.5
-
10
-
-
34247103036
-
A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance
-
DOI 10.1161/CIRCULATIONAHA.106.648790
-
Tanner MA, Galanello R, Dessi C et al. A randomised, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassaemia major using cardiovascular magnetic resonance. Circulation. 2007;115(14): 1876-1884 (Pubitemid 46598901)
-
(2007)
Circulation
, vol.115
, Issue.14
, pp. 1876-1884
-
-
Tanner, M.A.1
Galanello, R.2
Dessi, C.3
Smith, G.C.4
Westwood, M.A.5
Agus, A.6
Roughton, M.7
Assomull, R.8
Nair, S.V.9
Walker, J.M.10
Pennell, D.J.11
-
11
-
-
27744544284
-
Advances in iron overload therapies. Prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NAll and their combinations
-
DOI 10.2174/092986705774463003
-
Kontoghiorghes GJ, Eracleous E, Economides Ch, Kolnagou A. Advances in iron overload therapies. Prospects of effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NAll, and their combinations. Curr Med Chem. 2005;12(23): 2663-2681 (Pubitemid 41601566)
-
(2005)
Current Medicinal Chemistry
, vol.12
, Issue.23
, pp. 2663-2681
-
-
Kontoghiorghes, G.J.1
Eracleous, E.2
Economides, C.3
Kolnagou, A.4
-
12
-
-
0027195024
-
Competition between L1 desferrioxamine and other chelators for iron and the effect of other metal ions on iron binding
-
Sheppard L, Kontoghiorghes GJ. Competition between L1, desferrioxamine and other chelators for iron and the effect of other metal ions on iron binding. Arzn Forsch/Drug Res. 1993;43(6): 659-663
-
(1993)
Arzn. Forsch./Drug. Res.
, vol.43
, Issue.6
, pp. 659-663
-
-
Sheppard, L.1
Kontoghiorghes, G.J.2
-
13
-
-
27744485989
-
Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease. The role of natural and synthetic chelators
-
DOI 10.2174/092986705774463030
-
Kontoghiorghes GJ, Kolnagou A. Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease. The role of natural and synthetic chelators. Curr Med Chem. 2005;12(23): 2695-2709 (Pubitemid 41601568)
-
(2005)
Current Medicinal Chemistry
, vol.12
, Issue.23
, pp. 2695-2709
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
-
14
-
-
34347370842
-
Selective iron chelation in Friedreich ataxia: Biologic and clinical implications
-
DOI 10.1182/blood-2006-12-065433
-
Boddaert N, Le Quan Sang KH, Rotig A, et al. Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood. 2007;110(1): 401-408 (Pubitemid 47026862)
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 401-408
-
-
Boddaert, N.1
Sang, K.H.L.Q.2
Rotig, A.3
Leroy-Willig, A.4
Gallet, S.5
Brunelle, F.6
Sidi, D.7
Thalabard, J.-C.8
Munnich, A.9
Cabantchik, Z.I.10
-
16
-
-
39149101255
-
Treatment of patients with glomerulonephritis with an oral iron chelator
-
Rajapurkar MM, Beliga R, Shah S. Treatment of patients with glomerulonephritis with an oral iron chelator. J Am Soc Nephrol. 2007;18: 57-58A.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
-
-
Rajapurkar, M.M.1
Beliga, R.2
Shah, S.3
-
17
-
-
52449091285
-
Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation
-
Forni GL, Balocco M, Cremonesi L, et al. Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation. Mov Disord. 2008;23(6): 904-907
-
(2008)
Mov. Disord.
, vol.23
, Issue.6
, pp. 904-907
-
-
Forni, G.L.1
Balocco, M.2
Cremonesi, L.3
-
18
-
-
70350685257
-
Prospects for introducing deferiprone as potent pharmaceutical antioxidant
-
Elite Ed
-
Kontoghiorghes GJ. Prospects for introducing deferiprone as potent pharmaceutical antioxidant. Front Biosci. (Elite Ed) 2009;1: 161-178
-
(2009)
Front Biosci.
, vol.1
, pp. 161-178
-
-
Kontoghiorghes, G.J.1
-
19
-
-
77649159219
-
Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia neurodegenerative renal and infectious diseases
-
Kontoghiorghes GJ, Kolnagou A, Peng CT, Shah SV, Aessopos A. Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases. Expert Opin Drug Saf. 2010;9(2): 20 1-206
-
(2010)
Expert. Opin. Drug. Saf.
, vol.9
, Issue.2-20
, pp. 1-206
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
Peng, C.T.3
Shah, S.V.4
Aessopos, A.5
-
20
-
-
36048939819
-
Intensive chelation therapy in β-thalassemia and possible adverse cardiac effects of desferrioxamine
-
DOI 10.1532/IJH97.E0637
-
Aessopos A, Kati M, Farmaki D, et al. Intensive chelation therapy in β-thalassemia and possible adverse cardiac effects of desferrioxamine. Int J Haematol. 2007;86(3): 212-215 (Pubitemid 350085808)
-
(2007)
International Journal of Hematology
, vol.86
, Issue.3
, pp. 212-215
-
-
Aessopos, A.1
Kati, M.2
Farmakis, D.3
Polonifi, E.4
Deftereos, S.5
Tsironi, M.6
-
21
-
-
70350664643
-
Uses and limitationsof serum ferritin magnetic resonance imaging T2 and T2* in the diagnosis of iron overload and in the ferrikinetics of normalization of the iron stores in thalassemia using the international committee on chelation deferiprone/deferoxamine combination protocol
-
Kolnagou A, Yazman D, Economides Ch, Eracleous E, Kontoghiorghes GJ. Uses and limitationsof serum ferritin, magnetic resonance imaging T2 and T2* in the diagnosis of iron overload and in the ferrikinetics of normalization of the iron stores in thalassemia using the International Committee on Chelation deferiprone/deferoxamine combination protocol. Hemoglobin. 2009;33(5): 312-322
-
(2009)
Hemoglobin.
, vol.33
, Issue.5
, pp. 312-322
-
-
Kolnagou, A.1
Yazman, D.2
Economides, C.H.3
Eracleous, E.4
Kontoghiorghes, G.J.5
-
22
-
-
33745551087
-
Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*
-
DOI 10.1080/03630260600642542, PII U17734049487347
-
Kolnagou A, Eracleous E, Economides Ch, Kontoghiorghes GJ. Low serum ferritin levels are misleading for detecting excess cardiac iron loading and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2*. Hemoglobin. 2006;30(2): 219-227 (Pubitemid 43977324)
-
(2006)
Hemoglobin
, vol.30
, Issue.2
, pp. 219-227
-
-
Kolnagou, A.1
Economides, C.2
Eracleous, E.3
Kontoghiorghes, G.4
-
23
-
-
0024337363
-
Survival and causes of death in thalassaemia major
-
Zurlo MG, De Stefano P, Borgna-Pignatti C, et al. Survival and causes of death in thalassaemia major. Lancet. 1989;2(8653): 27-30 (Pubitemid 19158169)
-
(1989)
Lancet
, vol.2
, Issue.8653
, pp. 27-30
-
-
Zurlo, M.G.1
De Stefano, P.2
Borgna-Pignatti, C.3
Di Palma, A.4
Piga, A.5
Melevendi, C.6
Di Gregorio, F.7
Burattini, M.G.8
Terzoli, S.9
-
24
-
-
0031876331
-
Survival and disease complications in thalassemia major
-
DOI 10.1111/j.1749-6632.1998.tb10479.x
-
Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and disease complications in thalassemia major. Ann NY Acad Sci. 1998;850: 227-231 (Pubitemid 28369763)
-
(1998)
Annals of the New York Academy of Sciences
, vol.850
, pp. 227-231
-
-
Borgna-Pignatti, C.1
Rugolotto, S.2
De Stefano, P.3
Piga, A.4
Di Gregorio, F.5
Gamberini, M.R.6
Sabato, V.7
Melevendi, C.8
Cappellini, M.D.9
Verlato, G.10
-
25
-
-
0347363715
-
Combined therapy with desferrioxamine and deferiprone in thalassemic patients: Effect on urinary iron excretion
-
Kattamis A, Kassou C, Berdousi H, Ladis V, Papassotiriou I, Kattamis C. Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion. Haematologica. 2003;88(12): 1423-25 (Pubitemid 38029728)
-
(2003)
Haematologica
, vol.88
, Issue.12
, pp. 1423-1425
-
-
Kattamis, A.1
Kassou, C.2
Berdousi, H.3
Ladis, V.4
Papassotiriou, I.5
Kattamis, C.6
-
26
-
-
77953768780
-
Introduction of higher doses of deferasirox: Better efficacy but not effective iron removal from the heart and increased risks of serious toxicities
-
Kontoghiorghes GJ. Introduction of higher doses of deferasirox: Better efficacy but not effective iron removal from the heart and increased risks of serious toxicities. Expert Opin Drug Saf. 2010;9(4): 633-641
-
(2010)
Expert. Opin. Drug. Saf.
, vol.9
, Issue.4
, pp. 633-641
-
-
Kontoghiorghes, G.J.1
-
27
-
-
70350643863
-
A new era in iron chelation therapy: The design of optimal individually adjusted iron chelation therapies for the complete removal of iron overload in thalassemia and other chronically transfused patients
-
Kontoghiorghes GJ.A new era in iron chelation therapy: the design of optimal, individually adjusted iron chelation therapies for the complete removal of iron overload in thalassemia and other chronically transfused patients. Hemoglobin. 2009;33(5): 332-338
-
(2009)
Hemoglobin.
, vol.33
, Issue.5
, pp. 332-338
-
-
Kontoghiorghes, G.J.1
-
28
-
-
33745564177
-
Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone implications in the treatment of thalassemia anemia of chronic disease cancer and other conditions
-
Kontoghiorghes GJ. Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions. Hemoglobin. 2006;30(2): 183-200
-
(2006)
Hemoglobin.
, vol.30
, Issue.2
, pp. 183-200
-
-
Kontoghiorghes, G.J.1
-
29
-
-
77953779950
-
The effect of deferasirox on cardiac iron in thalassemia major: Impact of total body iron stores
-
Wood JC, Kang BP, Thompson A, et al. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010;116(4): 537-543
-
(2010)
Blood
, vol.116
, Issue.4
, pp. 537-543
-
-
Wood, J.C.1
Kang, B.P.2
Thompson, A.3
-
30
-
-
78650982192
-
Deferasirox deferiprone and desferrioxamine treatment in thalassemia major patients: Cardiac iron and function comparison determined by quantitative magnetic resonance imaging
-
Pepe A, Meloni A, Capra M, et al. Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: cardiac iron and function comparison determined by quantitative magnetic resonance imaging. Haematologica. 2010;96(1): 41-47
-
(2010)
Haematologica.
, vol.96
, Issue.1
, pp. 41-47
-
-
Pepe, A.1
Meloni, A.2
Capra, M.3
|