메뉴 건너뛰기




Volumn 58, Issue 4, 2012, Pages 365-375

Pharmacological therapy for acute pancreatitis: Where are we now? Where are we going?

Author keywords

Drug therapy; Octreotide; Pancreatitis; Protease inhibitors

Indexed keywords

ACETYLCYSTEINE; ACTIVATED PROTEIN C; ALANYLGLUTAMINE; ANTIBIOTIC AGENT; ANTIOXIDANT; APROTININ; ASCORBIC ACID; DROTRECOGIN; GABEXATE MESILATE; GLUTAMINE; IMIPENEM; IMMUNOMODULATING AGENT; INDOMETACIN; LEXIPAFANT; NAFAMSTAT; NONSTEROID ANTIINFLAMMATORY AGENT; OCTREOTIDE; PLACEBO; PROBIOTIC AGENT; PROTEINASE INHIBITOR; S ADENOSYLMETHIONINE; SELENIUM; SOMATOSTATIN; STOMACH SECRETION INHIBITOR;

EID: 84873508189     PISSN: 1121421X     EISSN: 18271642     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (11)

References (76)
  • 2
    • 34547929954 scopus 로고    scopus 로고
    • Action of antiproteases on the inflammatory response in acute pancreatitis
    • Chen CC, Wang SS, Lee FY. Action of antiproteases on the inflammatory response in acute pancreatitis. JOP 2007;8(4 Suppl):488-94.
    • (2007) JOP , vol.8 , Issue.4 SUPPL. , pp. 488-494
    • Chen, C.C.1    Wang, S.S.2    Lee, F.Y.3
  • 4
    • 33947318807 scopus 로고    scopus 로고
    • Acute Pancreatitis: Bench to the Bedside
    • DOI 10.1053/j.gastro.2007.01.055, PII S0016508507003095
    • Pandol SJ, Saluja AK, Imrie CW, Banks PA. Acute pancreatitis: bench to the bedside. Gastroenterology 2007;132:1127-51. (Pubitemid 46440879)
    • (2007) Gastroenterology , vol.132 , Issue.3 , pp. 1127-1151
    • Pandol, S.J.1    Saluja, A.K.2    Imrie, C.W.3    Banks, P.A.4
  • 5
    • 33646676272 scopus 로고    scopus 로고
    • Clinical practice. Acute pancreatitis
    • Whitcomb DC. Clinical practice. Acute pancreatitis. N Engl J Med 2006;354:2142-50.
    • (2006) N Engl J Med , vol.354 , pp. 2142-2150
    • Whitcomb, D.C.1
  • 7
    • 77954260431 scopus 로고    scopus 로고
    • Inflammation and immunosuppression in severe acute pancreatitis
    • Kylanpaa ML, Repo H, Puolakkainen PA. Inflammation and immunosuppression in severe acute pancreatitis. World J Gastroenterol 2010;16:2867-72.
    • (2010) World J Gastroenterol , vol.16 , pp. 2867-2872
    • Kylanpaa, M.L.1    Repo, H.2    Puolakkainen, P.A.3
  • 8
    • 0033804768 scopus 로고    scopus 로고
    • Inflammatory mediators in human acute pancreatitis: Clinical and pathophysiological implications
    • Mayer J, Rau B, Gansauge F, Beger HG. Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications. Gut 2000;47:546-52.
    • (2000) Gut , vol.47 , pp. 546-552
    • Mayer, J.1    Rau, B.2    Gansauge, F.3    Beger, H.G.4
  • 10
    • 38549084597 scopus 로고    scopus 로고
    • Early endoscopic retrograde cholangiopancreatography versus conservative management in acute biliary pancreatitis without cholangitis: A meta-analysis of randomized trials
    • DOI 10.1097/SLA.0b013e31815edddd, PII 0000065820080200000007
    • Petrov MS, van Santvoort HC, Besselink MG, van der Heijden GJ, van Erpecum KJ, Gooszen HG. Early endoscopic retrograde cholangiopancreatography versus conservative management in acute biliary pancreatitis without cholangitis: a meta-analysis of randomized trials. Ann Surg 2008;247:250-7. (Pubitemid 351156766)
    • (2008) Annals of Surgery , vol.247 , Issue.2 , pp. 250-257
    • Petrov, M.S.1    Van Santvoort, H.C.2    Besselink, M.G.H.3    Van Der, H.G.J.M.G.4    Van Erpecum, K.J.5    Gooszen, H.G.6
  • 11
    • 84855186468 scopus 로고    scopus 로고
    • Early cholecystectomy and ERCP are associated with reduced readmissions for acute biliary pancreatitis: A nationwide, population-based study
    • Nguyen GC, Rosenberg M, Chong RY, Chong CA. Early cholecystectomy and ERCP are associated with reduced readmissions for acute biliary pancreatitis: a nationwide, population-based study. Gastrointest Endosc 2012;75:47-55.
    • (2012) Gastrointest Endosc , vol.75 , pp. 47-55
    • Nguyen, G.C.1    Rosenberg, M.2    Chong, R.Y.3    Chong, C.A.4
  • 13
    • 0018185567 scopus 로고
    • Glucagon therapy in acute pancreatitis. Report of a double-blind trial
    • Durr HK, Maroske D, Zelder O, Bode JC. Glucagon therapy in acute pancreatitis. Report of a double-blind trial. Gut. 1978;19:175-9. (Pubitemid 8318427)
    • (1978) Gut , vol.19 , Issue.3 , pp. 175-179
    • Duerr, H.K.1    Maroske, D.2    Zelder, O.3    Bode C.., J.4
  • 15
    • 0018573599 scopus 로고
    • A double-blind trial of synthetic salmon calcitonin in the treatment of acute pancreatitis
    • Goebell H, Ammann R, Herfarth C, Horn J, Hotz J, Knoblauch M et al. A double-blind trial of synthetic salmon calcitonin in the treatment of acute pancreatitis. Scand J Gastroenterol. 1979;14:881-9. (Pubitemid 10161403)
    • (1979) Scandinavian Journal of Gastroenterology , vol.14 , Issue.7 , pp. 881-889
    • Goebell, H.1    Ammann, R.2    Herfarth, C..3
  • 16
  • 18
    • 0024583591 scopus 로고
    • Somatostatin in the treatment of acute pancreatitis: A prospective randomised controlled trial
    • Choi TK, Mok F, Zhan WH, Fan ST, Lai EC, Wong J. Somatostatin in the treatment of acute pancreatitis: a prospective randomised controlled trial. Gut. 1989;30:223-7. (Pubitemid 19058876)
    • (1989) Gut , vol.30 , Issue.2 , pp. 223-227
    • Choi, T.K.1    Mok, F.2    Zhan, W.H.3    Fan, S.T.4    Lai, E.C.S.5    Wong, J.6
  • 21
    • 0027471573 scopus 로고
    • Controlled trial of high-dose octreotide in treatment of acute pancreatitis. Evidence of improvement in disease severity
    • Beechey-Newman N. Controlled trial of high-dose octreotide in treatment of acute pancreatitis. Evidence of improvement in disease severity. Dig Dis Sci. 1993;38:644-7. (Pubitemid 23121270)
    • (1993) Digestive Diseases and Sciences , vol.38 , Issue.4 , pp. 644-647
    • Beechey-Newman, N.1
  • 23
    • 0030897882 scopus 로고    scopus 로고
    • A randomized, controlled trial of octreotide in the management of patients with acute pancreatitis
    • McKay C, Baxter J, Imrie C. A randomized, controlled trial of octreotide in the management of patients with acute pancreatitis. Int J Pancreatol. 1997;21:13-9. (Pubitemid 27184639)
    • (1997) International Journal of Pancreatology , vol.21 , Issue.1 , pp. 13-19
    • McKay, C.1    Baxter, J.2    Imrie, C.3
  • 24
    • 0028008478 scopus 로고
    • Octreotide in the treatment of acute pancreatitis: Results of a unicenter prospective trial with three different octreotide dosages
    • Binder M, Uhl W, Friess H, Malfertheiner P, Buchler MW. Octreotide in the treatment of acute pancreatitis: results of a unicenter prospective trial with three different octreotide dosages. Digestion. 1994;55 Suppl 1:20-3. (Pubitemid 24020274)
    • (1994) Digestion , vol.55 , Issue.SUPPL. 1 , pp. 20-23
    • Binder, M.1    Uhl, W.2    Friess, H.3    Malfertheiner, P.4    Buchler, M.W.5
  • 25
    • 0032966293 scopus 로고    scopus 로고
    • A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis
    • Uhl W, Buchler MW, Malfertheiner P, Beger HG, Adler G, Gaus W. A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis. Gut. 1999;45:97-104. (Pubitemid 29301852)
    • (1999) Gut , vol.45 , Issue.1 , pp. 97-104
    • Uhl, W.1    Buchler, M.W.2    Malfertheiner, P.3    Beger, H.G.4    Adler, G.5    Gaus, W.6
  • 26
    • 31844442651 scopus 로고    scopus 로고
    • Evidence-based treatment of acute pancreatitis: A look at established paradigms
    • DOI 10.1097/01.sla.0000197334.58374.70
    • Heinrich S, Schafer M, Rousson V, Clavien PA. Evidence-based treatment of acute pancreatitis: a look at established paradigms. Ann Surg 2006;243:154-68. (Pubitemid 43185433)
    • (2006) Annals of Surgery , vol.243 , Issue.2 , pp. 154-168
    • Heinrich, S.1    Schafer, M.2    Rousson, V.3    Clavien, P.-A.4
  • 27
    • 0016044115 scopus 로고
    • A controlled trial of Trasylol in the treatment of acute pancreatitis
    • Trapnell JE, Rigby CC, Talbot CH, Duncan EH. A controlled trial of Trasylol in the treatment of acute pancreatitis. Br J Surg. 1974;61:177-82.
    • (1974) Br J Surg , vol.61 , pp. 177-182
    • Trapnell, J.E.1    Rigby, C.C.2    Talbot, C.H.3    Duncan, E.H.4
  • 28
    • 0027930828 scopus 로고
    • High-dose intraperitoneal aprotinin treatment of acute severe pancreatitis: A double-blind randomized multi-center trial
    • DOI 10.1007/BF02361247
    • Berling R, Genell S, Ohlsson K. High-dose intraperitoneal aprotinin treatment of acute severe pancreatitis: a double-blind randomized multi-center trial. J Gastroenterol. 1994;29:479-85. (Pubitemid 24262718)
    • (1994) Journal of Gastroenterology , vol.29 , Issue.4 , pp. 479-485
    • Berling, R.1    Genell, I.S.2    Ohlsson, K.3
  • 29
    • 0027367644 scopus 로고
    • Gabexate mesilate vs aprotinin in human acute pancreatitis (GA.ME.P.A.): A prospective, randomized, double-blind multicenter study
    • Pederzoli P, Cavallini G, Falconi M, Bassi C. Gabexate mesilate vs aprotinin in human acute pancreatitis (GA.ME.P.A.). A prospective, randomized, double-blind multicenter study. Int J Pancreatol. 1993;14:117-24. (Pubitemid 23326230)
    • (1993) International Journal of Pancreatology , vol.14 , Issue.2 , pp. 117-124
    • Pederzoli, P.1    Cavallini, G.2    Falconi, M.3    Bassi, C.4
  • 31
    • 0030968627 scopus 로고    scopus 로고
    • Gabexate mesilate improves pancreatic microcirculation and reduces lung edema in a rat model of acute pancreatitis
    • Chen HM, Shyr MH, Chen MF. Gabexate mesilate improves pancreatic microcirculation and reduces lung edema in a rat model of acute pancreatitis. J Formos Med Assoc. 1997;96:704-9.
    • (1997) J Formos Med Assoc , vol.96 , pp. 704-709
    • Chen, H.M.1    Shyr, M.H.2    Chen, M.F.3
  • 32
    • 0020561930 scopus 로고
    • Therapy of acute pancreatitis with a synthetic protease and phospholipase A2 inhibitor gabexate mesilate
    • Freise J. [Therapy of acute pancreatitis with a synthetic protease and phospholipase A2 inhibitor gabexate mesilate]. Fortschr Med. 1983;101(31-32):1432-6.
    • (1983) Fortschr Med , vol.101 , Issue.31-32 , pp. 1432-1436
    • Freise, J.1
  • 33
    • 0022614976 scopus 로고
    • Gabexate mesilate in the treatment of acute pancreatitis. Results of a Hannover multicenter double-blind study with 50 patients
    • Freise J, Melzer P, Schmidt FW, Horbach L. [Gabexate mesilate in the treatment of acute pancreatitis. Results of a Hannover multicenter double-blind study with 50 patients]. Z Gastroenterol. 1986;24:200-11.
    • (1986) Z Gastroenterol , vol.24 , pp. 200-211
    • Freise, J.1    Melzer, P.2    Schmidt, F.W.3    Horbach, L.4
  • 34
    • 34547930924 scopus 로고    scopus 로고
    • Antiproteases in the treatment of acute pancreatitis
    • Kitagawa M, Hayakawa T. Antiproteases in the treatment of acute pancreatitis. JOP 2007;8(4 Suppl):518-25. (Pubitemid 47263694)
    • (2007) Journal of the Pancreas , vol.8 , Issue.4 , pp. 518-525
    • Kitagawa, M.1    Hayakawa, T.2
  • 35
    • 77955220276 scopus 로고    scopus 로고
    • The results of severe acute pancreatitis treatment with continuous regional arterial infusion of protease inhibitor and antibiotic: A randomized controlled study
    • Piascik M, Rydzewska G, Milewski J, Olszewski S, Furmanek M, Walecki J et al. The results of severe acute pancreatitis treatment with continuous regional arterial infusion of protease inhibitor and antibiotic: a randomized controlled study. Pancreas 2010;39:863-7.
    • (2010) Pancreas , vol.39 , pp. 863-867
    • Piascik, M.1    Rydzewska, G.2    Milewski, J.3    Olszewski, S.4    Furmanek, M.5    Walecki, J.6
  • 36
    • 0029915798 scopus 로고    scopus 로고
    • Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis
    • DOI 10.1016/S0002-9610(97)89617-1
    • Takeda K, Matsuno S, Sunamura M, Kakugawa Y. Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis. Am J Surg. 1996;171:394-8. (Pubitemid 26105206)
    • (1996) American Journal of Surgery , vol.171 , Issue.4 , pp. 394-398
    • Takeda, K.1    Matsuno, S.2    Sunamura, M.3    Kakugawa, Y.4
  • 37
    • 1942539924 scopus 로고    scopus 로고
    • Efficacy of Continuous Regional Arterial Infusion of a Protease Inhibitor and Antibiotic for Severe Acute Pancreatitis in Patients Admitted to an Intensive Care Unit
    • DOI 10.1097/00006676-200405000-00003
    • Imaizumi H, Kida M, Nishimaki H, Okuno J, Kataoka Y, Kida Y et al. Efficacy of continuous regional arterial infusion of a protease inhibitor and antibiotic for severe acute pancreatitis in patients admitted to an intensive care unit. Pancreas 2004;28:369-73. (Pubitemid 38509739)
    • (2004) Pancreas , vol.28 , Issue.4 , pp. 369-373
    • Imaizumi, H.1    Kida, M.2    Nishimaki, H.3    Okuno, J.4    Kataoka, Y.5    Kida, Y.6    Soma, K.7    Saigenji, K.8
  • 38
    • 0035552241 scopus 로고    scopus 로고
    • Benefit of Continuous Regional Arterial Infusion of Protease Inhibitor and Antibiotic in the Management of Acute Necrotizing Pancreatitis
    • DOI 10.1159/000055879
    • Takeda K, Yamauchi J, Shibuya K, Sunamura M, Mikami Y, Matsuno S. Benefit of continuous regional arterial infusion of protease inhibitor and antibiotic in the management of acute necrotizing pancreatitis. Pancreatology 2001;1:668-73. (Pubitemid 33674965)
    • (2001) Pancreatology , vol.1 , Issue.6 , pp. 668-673
    • Takeda, K.1    Yamauchi, J.2    Shibuya, K.3    Sunamura, M.4    Mikami, Y.5    Matsuno, S.6
  • 41
    • 23744480795 scopus 로고    scopus 로고
    • Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis
    • DOI 10.1186/cc3777
    • Jamdar S, Siriwardena AK. Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis. Crit Care 2005;9:321-2. (Pubitemid 41136264)
    • (2005) Critical Care , vol.9 , Issue.4 , pp. 321-322
    • Jamdar, S.1    Siriwardena, A.K.2
  • 43
    • 20444370043 scopus 로고    scopus 로고
    • The effect of activated protein C on experimental acute necrotizing pancreatitis
    • Yamanel L, Mas MR, Comert B, Isik AT, Aydin S, Mas N et al. The effect of activated protein C on experimental acute necrotizing pancreatitis. Crit Care 2005;9:R184-90.
    • (2005) Crit Care , vol.9
    • Yamanel, L.1    Mas, M.R.2    Comert, B.3    Isik, A.T.4    Aydin, S.5    Mas, N.6
  • 44
    • 36348969579 scopus 로고    scopus 로고
    • Activated protein C, an anticoagulant polypeptide, ameliorates severe acute pancreatitis via regulation of mitogen-activated protein kinases
    • DOI 10.1007/s00535-007-2104-2
    • Chen P, Zhang Y, Qiao M, Yuan Y. Activated protein C, an anticoagulant polypeptide, ameliorates severe acute pancreatitis via regulation of mitogen-activated protein kinases. J Gastroenterol 2007;42:887-96. (Pubitemid 350142769)
    • (2007) Journal of Gastroenterology , vol.42 , Issue.11 , pp. 887-896
    • Chen, P.1    Zhang, Y.2    Qiao, M.3    Yuan, Y.4
  • 45
    • 13444303827 scopus 로고    scopus 로고
    • Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model
    • DOI 10.1097/01.CCM.0000153415.04995.88
    • Iba T, Kidokoro A, Fukunaga M, Nagakari K, Shirahama A, Ida Y. Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model. Crit Care Med 2005;33:368-72. (Pubitemid 40216551)
    • (2005) Critical Care Medicine , vol.33 , Issue.2 , pp. 368-372
    • Iba, T.1    Kidokoro, A.2    Fukunaga, M.3    Nagakari, K.4    Shirahama, A.5    Ida, Y.6
  • 46
    • 3342931341 scopus 로고    scopus 로고
    • The use of drotrecogin alfa (activated) in severe sepsis during acute pancreatitis - Two case studies
    • Machala W, Wachowicz N, Komorowska A, Gaszynski W. The use of drotrecogin alfa (activated) in severe sepsis during acute pancreatitis-two case studies. Med Sci Monit 2004;10:CS31-6. (Pubitemid 38988181)
    • (2004) Medical Science Monitor , vol.10 , Issue.7
    • Machala, W.1    Wachowicz, N.2    Komorowska, A.3    Gaszynski, W.4
  • 47
  • 48
    • 0021056701 scopus 로고
    • The release of platelet-activating factor from human endothelial cells in culture
    • Camussi G, Aglietta M, Malavasi F, Tetta C, Piacibello W, Sanavio F et al. The release of platelet-activating factor from human endothelial cells in culture. J Immunol. 1983;131:2397-403. (Pubitemid 14227442)
    • (1983) Journal of Immunology , vol.131 , Issue.5 , pp. 2397-2403
    • Camussi, G.1    Aglietta, M.2    Malavasi, F.3
  • 49
    • 0019504531 scopus 로고
    • Release of platelet-activating factor in human pathology. I. Evidence for the occurrence of basophil degranulation and release of platelet-activating factor in systemic lupus erythematosus
    • Camussi G, Tetta C, Coda R, Benveniste J. Release of platelet-activating factor in human pathology. I. Evidence for the occurrence of basophil degranulation and release of platelet-activating factor in systemic lupus erythematosus. Lab Invest 1981;44:241-51. (Pubitemid 11143379)
    • (1981) Laboratory Investigation , vol.44 , Issue.3 , pp. 241-251
    • Camussi, G.1    Tetta, C.2    Coda, R.3    Benveniste, J.4
  • 51
    • 0022555858 scopus 로고
    • Platelet activating factor: A biologically active phosphoglyceride
    • Hanahan DJ. Platelet activating factor: a biologically active phosphoglyceride. Annu Rev Biochem 1986;55:483-509. (Pubitemid 16070778)
    • (1986) Annual Review of Biochemistry , vol.VOL. 55 , pp. 483-509
    • Hanahan, D.J.1
  • 53
    • 0027284672 scopus 로고
    • Release of platelet-activating factor in acute experimental pancreatitis
    • Kald B, Kald A, Ihse I, Tagesson C. Release of platelet-activating factor in acute experimental pancreatitis. Pancreas 1993;8:440-2. (Pubitemid 23183286)
    • (1993) Pancreas , vol.8 , Issue.4 , pp. 440-442
    • Kald, B.1    Kald, A.2    Ihse, I.3    Tagesson, C.4
  • 54
    • 0026786596 scopus 로고
    • Role of platelet activating factor in pathogenesis of acute pancreatitis in rats
    • Konturek SJ, Dembinski A, Konturek PJ, Warzecha Z, Jaworek J, Gustaw P et al. Role of platelet activating factor in pathogenesis of acute pancreatitis in rats. Gut 1992;33:1268-74.
    • (1992) Gut , vol.33 , pp. 1268-1274
    • Konturek, S.J.1    Dembinski, A.2    Konturek, P.J.3    Warzecha, Z.4    Jaworek, J.5    Gustaw, P.6
  • 55
    • 0028029519 scopus 로고
    • Amelioration of experimental acute pancreatitis with a potent platelet-activating factor antagonist
    • DOI 10.1002/bjs.1800811224
    • Formela LJ, Wood LM, Whittaker M, Kingsnorth AN. Amelioration of experimental acute pancreatitis with a potent platelet-activating factor antagonist. Br J Surg 1994;81:1783-5. (Pubitemid 24372370)
    • (1994) British Journal of Surgery , vol.81 , Issue.12 , pp. 1783-1785
    • Formela, L.J.1    Wood, L.M.2    Whittaker, M.3    Kingsnorth, A.N.4
  • 56
    • 0028876181 scopus 로고
    • Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis
    • Kingsnorth AN, Galloway SW, Formela LJ. Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Br J Surg 1995;82:1414-20.
    • (1995) Br J Surg , vol.82 , pp. 1414-1420
    • Kingsnorth, A.N.1    Galloway, S.W.2    Formela, L.J.3
  • 57
    • 0035159658 scopus 로고    scopus 로고
    • Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
    • DOI 10.1136/gut.48.1.62
    • Johnson CD, Kingsnorth AN, Imrie CW, McMahon MJ, Neoptolemos JP, McKay C et al. Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. Gut 2001;48:62-9. (Pubitemid 32042643)
    • (2001) Gut , vol.48 , Issue.1 , pp. 62-69
    • Johnson, C.D.1    Kingsnorth, A.N.2    Imrie, C.W.3    McMahon, M.J.4    Neoptolemos, J.P.5    McKay, C.6    Toh, S.K.C.7    Skaife, P.8    Leeder, P.C.9    Wilson, P.10    Larvin, M.11    Curtis, L.D.12
  • 59
    • 0027717934 scopus 로고
    • Inflammatory mediators and cytokines - New aspects of the pathophysiology and assessment of severity of acute pancreatitis?
    • Gross V, Leser HG, Heinisch A, Scholmerich J. Inflammatory mediators and cytokines - new aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology 1993;40:522-30. (Pubitemid 24006279)
    • (1993) Hepato-Gastroenterology , vol.40 , Issue.6 , pp. 522-530
    • Gross, V.1    Leser, H.-G.2    Heinisch, A.3    Scholmerich, J.4
  • 60
    • 84873513762 scopus 로고    scopus 로고
    • Clinical pancreatology I: Pancreatic medical history
    • Andren-Sandberg A. Clinical pancreatology I: Pancreatic medical history. N Am J Med Sci 2010;2:502-9.
    • (2010) N Am J Med Sci , vol.2 , pp. 502-509
    • Andren-Sandberg, A.1
  • 61
    • 0018072140 scopus 로고
    • Indomethacin treatment of acute experimental pancreatitis in the rat
    • Lankisch PG, Koop H, Winckler K, Kunze H, Vogt W. Indomethacin treatment of acute experimental pancreatitis in the rat. Scand J Gastroenterol 1978;13:629-33. (Pubitemid 9003867)
    • (1978) Scandinavian Journal of Gastroenterology , vol.13 , Issue.5 , pp. 629-633
    • Lankisch, P.G.1    Koop, H.2    Winckler, K.3
  • 63
    • 0021886350 scopus 로고
    • Indomethacin treatment of acute pancreatitis. A controlled double-blind trial
    • Ebbehoj N, Friis J, Svendsen LB, Bulow S, Madsen P. Indomethacin treatment of acute pancreatitis. A controlled double-blind trial. Scand J Gastroenterol 1985;20:798-800. (Pubitemid 15015111)
    • (1985) Scandinavian Journal of Gastroenterology , vol.20 , Issue.7 , pp. 798-800
    • Ebbehoj, N.1    Friis, J.2    Svendsen, B.3
  • 64
    • 0034052439 scopus 로고    scopus 로고
    • Pathophysiologic role of oxygen free radicals in acute pancreatitis: Initiating event or mediator of tissue damage?
    • DOI 10.1097/00000658-200003000-00008
    • Rau B, Poch B, Gansauge F, Bauer A, Nussler AK, Nevalainen T et al. Pathophysiologic role of oxygen free radicals in acute pancreatitis: initiating event or mediator of tissue damage? Ann Surg 2000;231:352-60. (Pubitemid 30137123)
    • (2000) Annals of Surgery , vol.231 , Issue.3 , pp. 352-360
    • Rau, B.1    Poch, B.2    Gansauge, F.3    Bauer, A.4    Nussler, A.K.5    Nevalainen, T.6    Schoenberg, M.H.7    Beger, H.G.8
  • 65
    • 80054031724 scopus 로고    scopus 로고
    • Antioxidant therapy in acute pancreatitis: Experimental and clinical evidence
    • Hackert T, Werner J. Antioxidant therapy in acute pancreatitis: experimental and clinical evidence. Antioxid Redox Signal 2011;15:2767-77.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 2767-2777
    • Hackert, T.1    Werner, J.2
  • 66
    • 0029118060 scopus 로고
    • Clinical trial of 24 hours treatment with glutathione precursors in acute panreatitis
    • Scharer N SP, Deardon D, Lee S, Taylor P, and Braganza JM. Clinical trial of 24 hours treatment with glutathione precursors in acute panreatitis. Clin Drug Investig 1995;10:147-57.
    • (1995) Clin Drug Investig , vol.10 , pp. 147-157
    • Scharer, N.S.P.1    Deardon, D.2    Lee, S.3    Taylor, P.4    Braganza, J.M.5
  • 67
    • 34948868191 scopus 로고    scopus 로고
    • Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis
    • DOI 10.1136/gut.2006.115873
    • Siriwardena AK, Mason JM, Balachandra S, Bagul A, Galloway S, Formela L et al. Randomised, double blind, placebo controlled trial of intravenous antioxidant (n-acetylcysteine, selenium, vitamin C) therapy in severe acute pancreatitis. Gut 2007;56:1439-44. (Pubitemid 47517841)
    • (2007) Gut , vol.56 , Issue.10 , pp. 1439-1444
    • Siriwardena, A.K.1    Mason, J.M.2    Balachandra, S.3    Bagul, A.4    Galloway, S.5    Formela, L.6    Hardman, J.G.7    Jamdar, S.8
  • 68
    • 77953242556 scopus 로고    scopus 로고
    • Effect of antioxidant therapy on hospital stay and complications in patients with early acute pancreatitis: A randomised controlled trial
    • Sateesh J, Bhardwaj P, Singh N, Saraya A. Effect of antioxidant therapy on hospital stay and complications in patients with early acute pancreatitis: a randomised controlled trial. Trop Gastroenterol 2009;30:201-6.
    • (2009) Trop Gastroenterol , vol.30 , pp. 201-206
    • Sateesh, J.1    Bhardwaj, P.2    Singh, N.3    Saraya, A.4
  • 71
    • 0027196395 scopus 로고
    • A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem
    • Pederzoli P, Bassi C, Vesentini S, Campedelli A. A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstet 1993;176:480-3. (Pubitemid 23138141)
    • (1993) Surgery Gynecology and Obstetrics , vol.176 , Issue.5 , pp. 480-483
    • Pederzoli, P.1    Bassi, C.2    Vesentini, S.3    Campedelli, A.4
  • 73
    • 0031216254 scopus 로고    scopus 로고
    • Management of otitis media: The case for more judicious and targeted antibiotic use
    • Schwartz B, Dowell S. Management of otitis media: the case for more judicious and targeted antibiotic use. HMO Pract 1997;11:139-40.
    • (1997) HMO Pract , vol.11 , pp. 139-140
    • Schwartz, B.1    Dowell, S.2
  • 74
    • 0035158312 scopus 로고    scopus 로고
    • Prophylactic antibiotic administration reduces sepsis and mortality in acute necrotizing pancreatitis: A meta-analysis
    • DOI 10.1097/00006676-200101000-00005
    • Sharma VK, Howden CW. Prophylactic antibiotic administration reduces sepsis and mortality in acute necrotizing pancreatitis: a meta-analysis. Pancreas 2001;22:28-31. (Pubitemid 32046211)
    • (2001) Pancreas , vol.22 , Issue.1 , pp. 28-31
    • Sharma, V.K.1    Howden, C.W.2
  • 75
    • 39049195917 scopus 로고    scopus 로고
    • Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis
    • Villatoro E, Mulla M, Larvin M. Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis. Cochrane Database Syst Rev 2010:CD002941.
    • (2010) Cochrane Database Syst Rev
    • Villatoro, E.1    Mulla, M.2    Larvin, M.3
  • 76
    • 84861308442 scopus 로고    scopus 로고
    • Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis
    • quiz e15-6
    • Mounzer R, Langmead CJ, Wu BU, Evans AC, Bishehsari F, Muddana V et al. Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis. Gastroenterology 2012;142:1476-82; quiz e15-6.
    • (2012) Gastroenterology , vol.142 , pp. 1476-1482
    • Mounzer, R.1    Langmead, C.J.2    Wu, B.U.3    Evans, A.C.4    Bishehsari, F.5    Muddana, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.