Neonatal lipopolysaccharide exposure induces long-lasting learning impairment, less anxiety-like response and hippocampal injury in adult rats

Neuroscience

Volumn 234, Issue , 2013, Pages 146-157

  Wang, K C ^a,b   Fan, L W ^c   Kaizaki, A ^d   Pang, Y ^c   Cai, Z ^c   Tien, L T ^b  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^d SHOWA UNIVERSITY   (Japan)

Author keywords

Anxiolytic behavior; Chronic inflammation; Hippocampus; Learning dysfunction; Lipopolysaccharide

Indexed keywords

INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NEURON SPECIFIC NUCLEAR PROTEIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; AXONAL INJURY; BRAIN INJURY; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; HIPPOCAMPAL CA1 REGION; LEARNING DISORDER; LONG TERM EXPOSURE; MAZE TEST; MENTAL TASK; MICROGLIA; NEWBORN PERIOD; NONHUMAN; OPEN FIELD BEHAVIOR; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTI-ANXIETY AGENTS; ANXIETY; ATROPHY; FEMALE; HIPPOCAMPUS; HYPERTROPHY; INTERLEUKIN-1BETA; LATERAL VENTRICLES; LEARNING; LIPOPOLYSACCHARIDES; MICROGLIA; MICROINJECTIONS; MOTOR ACTIVITY; NERVE DEGENERATION; RATS;

EID: 84873494993     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.12.049     Document Type: Article

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