Low-molecular-weight adiponectin is more closely associated with episodes of asthma than high-molecularweight adiponectin

Endocrine Journal

Volumn 60, Issue 1, 2013, Pages 119-125

  Matsumoto, Yuuki ^a   Toyomasu, Kouji ^b   Uchimura, Naohisa ^a   Ishitake, Tatsuya ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KURUME UNIVERSITY   (Japan)

Author keywords

Asthma; Ghrelin; LMW adiponectin; Male; MMW adiponectin

Indexed keywords

ADIPONECTIN; GHRELIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HIGH MOLECULAR WEIGHT ADIPONECTIN; INSULIN; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW MOLECULAR WEIGHT ADIPONECTIN; MIDDLE MOLECULAR WEIGHT ADIPONECTIN; UNCLASSIFIED DRUG;

ADULT; AGE; ASTHMA; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HISTORY; HORMONE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; MALE; NOTE; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; UNIVERSITY STUDENT; WAIST CIRCUMFERENCE;

ADIPONECTIN; ADOLESCENT; ADULT; ASTHMA; FEMALE; GHRELIN; HUMANS; INFLAMMATION; LEPTIN; MALE;

EID: 84873487548     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ12-0277     Document Type: Note

References (31)

1. Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, et al. (2003) Globular adiponectin protected ob/ob mice from diabetes and apoE-deficient mice from atherosclerosis. J Biol Chem 278: 2461-2468.
2. Zoccali C, Mallamaci F, Triperi G, Benedetto FA, Cutrupi S, et al. (2002) Adiponectin, Metabolic risk factors, and cardiovascular events among patients with endstage renal disease. J Am Soc Nephrol 13: 134-141.
3. Verges B, Petit JM, Duvillard L, Dautin G, Florentn E, et al. (2006) Adiponectin is an important determinant of apoA-I catabolism. Arterioscler Thromb Vasc Biol 26: 1364-1369.
4. Neumeier M, Sigruener A, Eggenhofer E, Weigert J, Weiss TS, et al. (2007) High molecular weight adiponectin reduces apolipoprotein B and E release in human hepatocytes. Biochem Biophys Res Commun 352: 543-548.
5. Minokoshi Y, Alquier T, Furukawa N, Kim Y, Lee A, et al. (2004) AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428: 569-574.
6. Saijo S, Nagata K, Nakano Y, Tobe T, Kobayashi Y. (2005) Inhibition by adiponectin of IL-8 production by human macrophages upon coculturing with late apoptotic cells. Biochem Biophys Res Commun 334: 1180-1183.
7. Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kiber MT, et al. (2007) Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J Clin Invent 117: 375-386.
8. Devaraj S, Torok N, Dasu MR, Samols D, Jialal I (2008) Adiponectin decreases C-reactive protein synthesis from endothelial cells: evidence for an adipose tissue-vascular loop. Arterioscler Thromb Vasc Biol 28: 1368-1374.
9. Schaffler A, Ehling A, Neumann E, Herfarth H, Tarner I, et al. (2003) Adipocytokines in synovial fluid. JAMA 290: 1709-1710.
10. Haugen F, Drevon CA (2007) Activation of nuclear factor-κb by high molecular weight and globular adiponectin. Endocinol 148: 5478-5486.
11. Sada KE, Yamasaki Y, Maruyama M, Sugiyama H, Yamamura M, et al. (2006) Altered levels of adipocytokines in association with insulin resistance in patients with systemic lupus erythematosus. J Rheumatol 33: 1545-1552.
12. Otero M, Lago R, Gomez R, Lago F, Dieguez C, et al. (2006) Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis. Ann Rheum Dis 65: 1198-1201.
13. Senolt L, Pavelka K, Housa D, Huluzik M (2006) Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis. Cytokine 35: 247-252.
14. Tomoda K, Yosikawa M, Itoh T, Tamaki S, Fukuoka A, et al. (2007) Elevated circulating plasma adiponectin in underweight patients with COPD. Chest 132: 135-140.
15. Yuksel H, Sogut A, Yilmaz O, Onur E, Dinc G (2012) Role of adipokines and hormones of obesity in childhood asthma. Allergy Asthma Immunol Res 4: 98-103.
16. Sood A, Cui X, Qualls C, Beckett WS, Gross MD, et al. (2008) Association between asthma and serum adiponectin concentration in women. Thorax 63: 877-882.
17. Sood A, Dominic E, Qualls C, Steffes MW, Thyagarajan B, et al. (2011) Serum adiponectin is associated with adverse outcomes of asthma in men but not in women. Front Pharmacol 2: 1-11.
18. Aso Y, Yamamoto R, Wakabayashi S, Uchida T, Takayanagi K, et al. (2006) Comparison of serum highmolecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin. Diabetes 55: 1954-1960.
19. Sood A, Qualls C, Schuyler M, Thyagarajan B, Steffes MW, et al. (2012) Low serum adiponectin predicts future risk for asthma in women. Am J Respir Crit Care Med 186: 41-47.
20. Matarese G, Moschos S, Mantzoros CS (2005) Leptin in immunology. J Immunol 174: 3137-3142.
21. Waseem T, Duxbury M, Ito H, Ashley SW, Robinson MK (2008) Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery 143: 334-342.
22. Bottner A, Kratzsch J, Muller G, Kapellen TM, Bluher S, et al. (2004) Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels. J Clin Endocrinol 89: 4053-4061.
23. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, et al. (1999) Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83.
24. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
25. Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, et al. (2000) Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20: 1595-1599.
26. Ryo M, Nakamura T, Kihara S, Kumada M, Shibazaki S, et al. (2004) Adiponectin as a biomarker of the metabolic syndrome. Circ J 68: 975-981.
27. Makino S (1984) Diagnostic criteria. Gendaiiryo 16: 749-752 (In Japanese).
28. Sood A, Camargo CA (2006) Association between leptin and asthma in adults. Thorax 61: 300-305.
29. Radon K, Schulze A, Schierl R, Dietrich-Gumperlein G, Nowak D (2008) Serum leptin and adiponectin levels and their association with allergic sensitization. Allergy 63: 1448-1454.
30. Ebinuma H, Miyazaki O, Yago H, Hara K, Yamauchi T, et al. (2006) A novel ELISA system for selective measurement of human adiponectinmultimers by using proteases. Clin Chim Acta 372: 47-53.
31. Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, et al. (2007) Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab 6: 55-68.