Distinctive age-related temporal cortical thinning in asymptomatic granulin gene mutation carriers

Neurobiology of Aging

Volumn 34, Issue 5, 2013, Pages 1462-1468

  Moreno, Fermín ^a,b,c   Sala Llonch, Roser ^d,e   Barandiaran, Myriam ^a,b,c   Sánchez Valle, Raquel ^e,f   Estanga, Ainara ^b,c   Bartrés Faz, David ^d,e   Sistiaga, Andone ^b,c,g   Alzualde, Ainhoa ^b,c   Fernández, Esther ^h   Martí Massó, José Félix ^a,b,c   López de Munain, Adolfo ^a,b,c   Indakoetxea, Begoña ^a,b,c  

^a HOSPITAL DONOSTIA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

^e INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^f HOSPITAL CLÍNIC   (Spain)

^g UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^h OSATEK Unidad de Donostia   (Spain)

Author keywords

Cortical thickness; Frontotemporal dementia; Frontotemporal lobar degeneration; Granulin; MRI; Preclinical; Progranulin

Indexed keywords

ALANINE; BRAIN PROTEIN; GLYCINE;

ADULT; AGE; ARTICLE; ASYMPTOMATIC DISEASE; BRAIN MAPPING; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); DISEASE ASSOCIATION; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; GRANULIN GENE; HETEROZYGOTE; HUMAN; LEFT HEMISPHERE; MALE; MENTAL PERFORMANCE; MIDDLE TEMPORAL GYRUS; NEUROPSYCHOLOGICAL TEST; ONSET AGE; PRIORITY JOURNAL; RIGHT HEMISPHERE; SUPERIOR TEMPORAL GYRUS; SUPERIOR TEMPORAL SULCUS; TEMPORAL CORTEX;

ADULT; AGED; AGING; CEREBRAL CORTEX; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HETEROZYGOTE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MUTATION;

EID: 84873461577     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.11.005     Document Type: Article

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