Higher susceptibility to experimental autoimmune encephalomyelitis in Muc1-deficient mice is associated with increased Th1/Th17 responses

Brain, Behavior, and Immunity

Volumn 29, Issue , 2013, Pages 70-81

  Yen, Jui Hung ^a   Xu, Shuyun ^a,b   Park, Yong Sung ^a   Ganea, Doina ^a   Kim, Kwang Chul ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Anti inflammatory; Dendritic cells; Experimental autoimmune encephalomyelitis (EAE); Muc1 mucin; Multiple sclerosis; Th1 Th17 cells

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MUCIN 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE SEVERITY; EX VIVO STUDY; INCIDENCE; INFLAMMATION; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL; TH17 CELL;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; INTERLEUKINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUCIN-1; MULTIPLE SCLEROSIS; REAL-TIME POLYMERASE CHAIN REACTION; SPLEEN; TH1 CELLS; TH17 CELLS;

EID: 84873460956     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2012.12.004     Document Type: Article

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