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Volumn 5, Issue 9, 2003, Pages 491-499

PA2.26 antigen (T1a/podoplanin): A small mucin-like transmembrane glycoprotein associated with cell migration and cancer

Author keywords

Cell migration; Lymphatic endothelium; Metastasis; Mucin; PA226; Podoplanin; T1a

Indexed keywords


EID: 84873437329     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (54)
  • 2
    • 0026737199 scopus 로고
    • Cell membrane-associated mucins and their adhesion-modulating properties
    • Hilkens J, Ligtenberg MJL, Vos HL, et al. Cell membrane-associated mucins and their adhesion-modulating properties. Trends Biochem Sci 1992;17:359-63.
    • (1992) Trends Biochem Sci , vol.17 , pp. 359-363
    • Hilkens, J.1    Ligtenberg, M.J.L.2    Vos, H.L.3
  • 3
    • 0037235146 scopus 로고    scopus 로고
    • Cell signaling through membrane mucins
    • Carraway KL, Ramsauer VP, Haq B, et al. Cell signaling through membrane mucins. BioEssays 2002;25:66-71.
    • (2002) BioEssays , vol.25 , pp. 66-71
    • Carraway, K.L.1    Ramsauer, V.P.2    Haq, B.3
  • 4
    • 0028950808 scopus 로고
    • Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components
    • Wesseling J, van der Valk SW, Vos HL, et al. Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components. J Cell Biol 1995;129:255-65.
    • (1995) J Cell Biol , vol.129 , pp. 255-265
    • Wesseling, J.1    Van Der Valk, S.W.2    Vos, H.L.3
  • 5
    • 0029937975 scopus 로고    scopus 로고
    • A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane associated mucin episialin/MUC1
    • Wesseling J, van der Valk SW, Hilkens J. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane associated mucin episialin/MUC1. Mol Biol Cell 1996;7:565-77.
    • (1996) Mol Biol Cell , vol.7 , pp. 565-577
    • Wesseling, J.1    Van Der Valk, S.W.2    Hilkens, J.3
  • 6
    • 0030999379 scopus 로고    scopus 로고
    • Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucin secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion
    • Zhang K, Baeckstrom D, Brevinge H, et al. Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucin secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion. Tumor Biol 1997;18:175-87.
    • (1997) Tumor Biol , vol.18 , pp. 175-187
    • Zhang, K.1    Baeckstrom, D.2    Brevinge, H.3
  • 7
    • 0029988114 scopus 로고    scopus 로고
    • Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumor cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte to E-selectin-expressing endothelial cells
    • Zhang K, Baeckstrom D, Brevinge H, et al. Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumor cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte to E-selectin-expressing endothelial cells. J Cell Biochem 1996;60:538-49.
    • (1996) J Cell Biochem , vol.60 , pp. 538-549
    • Zhang, K.1    Baeckstrom, D.2    Brevinge, H.3
  • 8
    • 0030958706 scopus 로고    scopus 로고
    • Interaction of the DF3/MUC1 breast carcinoma-associated antigen and b-catenin in cell adhesion
    • Yamamoto M, Bharti A, Ly I, et al. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and b-catenin in cell adhesion. J Biol Chem 1997;272:12492-4.
    • (1997) J Biol Chem , vol.272 , pp. 12492-12494
    • Yamamoto, M.1    Bharti, A.2    Ly, I.3
  • 9
    • 0034715942 scopus 로고    scopus 로고
    • The integration of cell adhesion with gene expression: The role of b-catenin
    • Ben-Ze'ev A, Shtutman M, Zhurinsky J. The integration of cell adhesion with gene expression: The role of b-catenin. Exp Cell Res 2000;261:75-82.
    • (2000) Exp Cell Res , vol.261 , pp. 75-82
    • Ben-Ze'ev, A.1    Shtutman, M.2    Zhurinsky, J.3
  • 10
    • 0031468441 scopus 로고    scopus 로고
    • Reversible disruption of cell-matrix and cell-cell interaction by overexpression of sialomucin complex
    • Komatsu M, Carraway CAC, Fregien NL, et al. Reversible disruption of cell-matrix and cell-cell interaction by overexpression of sialomucin complex. J Biol Chem 1997;272:33245-54.
    • (1997) J Biol Chem , vol.272 , pp. 33245-33254
    • Komatsu, M.1    Carraway, C.A.C.2    Fregien, N.L.3
  • 11
    • 0037168129 scopus 로고    scopus 로고
    • Muc4/sialomucin complex, the intramembrane ErbB2 ligan, induces specific phosphorylation of ErbB2 and enhances expression of p27 (kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways
    • Jepson S, Komatsu M, Haq B, et al. Muc4/sialomucin complex, the intramembrane ErbB2 ligan, induces specific phosphorylation of ErbB2 and enhances expression of p27 (kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways. Oncogene 2002; 21:7524-32.
    • (2002) Oncogene , vol.21 , pp. 7524-7532
    • Jepson, S.1    Komatsu, M.2    Haq, B.3
  • 12
  • 13
    • 0027754171 scopus 로고
    • Mucins in the mainstream
    • Shimizu Y, Shaw S. Mucins in the mainstream. Nature 1993;366:630-1.
    • (1993) Nature , vol.366 , pp. 630-631
    • Shimizu, Y.1    Shaw, S.2
  • 14
    • 0030812692 scopus 로고    scopus 로고
    • Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis
    • Gandarillas A, Scholl FG, Benito N, et al. Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis. Mol Carcinog 1997;20:10-8.
    • (1997) Mol Carcinog , vol.20 , pp. 10-18
    • Gandarillas, A.1    Scholl, F.G.2    Benito, N.3
  • 15
    • 0033398793 scopus 로고    scopus 로고
    • Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes
    • Scholl FG, Gamallo C, Vilaró S, et al. Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes. J Cell Sci 1999;112: 4601-13.
    • (1999) J Cell Sci , vol.112 , pp. 4601-4613
    • Scholl, F.G.1    Gamallo, C.2    Vilaró, S.3
  • 16
    • 0032559637 scopus 로고    scopus 로고
    • Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2
    • Yonemura S, Hirao M, Doi Y, et al. Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol 1998;140:885-95.
    • (1998) J Cell Biol , vol.140 , pp. 885-895
    • Yonemura, S.1    Hirao, M.2    Doi, Y.3
  • 17
  • 18
    • 0037039315 scopus 로고    scopus 로고
    • Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis
    • Ino Y, Gotoh M, Sakamoto M, et al. Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. Proc Natl Acad Sci USA 2002;99:365-70.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 365-370
    • Ino, Y.1    Gotoh, M.2    Sakamoto, M.3
  • 19
    • 0025519997 scopus 로고
    • Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells
    • Nose K, Saito H, Kuroki T. Isolation of a gene sequence induced later by tumor-promoting 12-O-tetradecanoylphorbol-13-acetate in mouse osteoblastic cells (MC3T3-E1) and expressed constitutively in ras-transformed cells. Cell Growth Differ 1990;1:511-8.
    • (1990) Cell Growth Differ , vol.1 , pp. 511-518
    • Nose, K.1    Saito, H.2    Kuroki, T.3
  • 20
    • 0026722290 scopus 로고
    • Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues
    • Farr AG, Berry ML, Kim A, et al. Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues. J Exp Med 1992;176:1477-82.
    • (1992) J Exp Med , vol.176 , pp. 1477-1482
    • Farr, A.G.1    Berry, M.L.2    Kim, A.3
  • 21
    • 0029881460 scopus 로고    scopus 로고
    • Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes
    • Wetterwald A, Hoffstetter W, Cecchini MG, et al. Characterization and cloning of the E11 antigen, a marker expressed by rat osteoblasts and osteocytes. Bone 1996;18: 25-132.
    • (1996) Bone , vol.18 , pp. 25-132
    • Wetterwald, A.1    Hoffstetter, W.2    Cecchini, M.G.3
  • 22
    • 0028984957 scopus 로고
    • Cloning, characterization, and development expression of a rat lung alveolar type i cell gene in embryonic endodermal and neural derivatives
    • Rishi AK, Joyce-Brady M, Fisher J, et al. Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives. Dev Biol 1995;167:294-306.
    • (1995) Dev Biol , vol.167 , pp. 294-306
    • Rishi, A.K.1    Joyce-Brady, M.2    Fisher, J.3
  • 23
    • 0032438031 scopus 로고    scopus 로고
    • Purification and analysis of RT140, a type i alveolar epithelial cell apical membrane protein
    • Gonzalez RF, Dobbs LG. Purification and analysis of RT140, a type I alveolar epithelial cell apical membrane protein. Biochim Biophys Acta 1998;1429:208-16.
    • (1998) Biochim Biophys Acta , vol.1429 , pp. 208-216
    • Gonzalez, R.F.1    Dobbs, L.G.2
  • 24
    • 0030796363 scopus 로고    scopus 로고
    • Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis
    • Breiteneder-Geleff S, Matsui, K, Soleiman A, et al. Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. Am J Pathol 1997;151:1141-52.
    • (1997) Am J Pathol , vol.151 , pp. 1141-1152
    • Breiteneder-Geleff, S.1    Matsui, K.2    Soleiman, A.3
  • 25
    • 0029076138 scopus 로고
    • Identification of a 40-kda cell surface sialoglycoprotein with the characteristics of a major influenza C virus receptor in a Madin-Darby canine kidney cell line
    • Zimmer G, Klenk H-D, Herrler G. Identification of a 40-kda cell surface sialoglycoprotein with the characteristics of a major influenza C virus receptor in a Madin-Darby canine kidney cell line. J Biol Chem 1995;270: 17815-22.
    • (1995) J Biol Chem , vol.270 , pp. 17815-17822
    • Zimmer, G.1    Klenk, H.-D.2    Herrler, G.3
  • 26
    • 0033565967 scopus 로고    scopus 로고
    • Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium
    • Zimmer G, Oefner F, von Messling V, et al. Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium. Biochem J 1999;341:277-84.
    • (1999) Biochem J , vol.341 , pp. 277-284
    • Zimmer, G.1    Oefner, F.2    Von Messling, V.3
  • 27
    • 0032109676 scopus 로고    scopus 로고
    • Evidence against a role of mouse, rat, and two cloned human T1a isoforms as a water channel or a regulator of aquoporin-type water channels
    • Ma T, Yang B, Matthay MA, et al. Evidence against a role of mouse, rat, and two cloned human T1a isoforms as a water channel or a regulator of aquoporin-type water channels. Am J Respir Cell Mol Biol 1998;19: 143-9.
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 143-149
    • Ma, T.1    Yang, B.2    Matthay, M.A.3
  • 28
    • 0035903330 scopus 로고    scopus 로고
    • Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages
    • Kriehuber E, Breiteneder-Geleff S, Groeger M, et al. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med 2001;194: 797-808.
    • (2001) J Exp Med , vol.194 , pp. 797-808
    • Kriehuber, E.1    Breiteneder-Geleff, S.2    Groeger, M.3
  • 29
    • 0030160454 scopus 로고    scopus 로고
    • T1a protein is developmentally regulated and expressed by alveolar type i cells, chroid plexus, and ciliary epithelia of adult rats
    • Williams MC, Cao YX, Hinds A, et al. T1a protein is developmentally regulated and expressed by alveolar type I cells, chroid plexus, and ciliary epithelia of adult rats. Am J Respir Cell Mol Biol 1996;14:577-85.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 577-585
    • Williams, M.C.1    Cao, Y.X.2    Hinds, A.3
  • 31
    • 0037376154 scopus 로고    scopus 로고
    • T1a, a lung type i cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth
    • Ramirez MI, Millien G, Hinds A, et al. T1a, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth. Dev Biol 2003;256:61-72.
    • (2003) Dev Biol , vol.256 , pp. 61-72
    • Ramirez, M.I.1    Millien, G.2    Hinds, A.3
  • 32
    • 0041312675 scopus 로고    scopus 로고
    • T1a/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema
    • Schacht V, Ramírez MI, Hong Y-K, et al. T1a/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J 2003;22:3546-56.
    • (2003) EMBO J , vol.22 , pp. 3546-3556
    • Schacht, V.1    Ramírez, M.I.2    Hong, Y.-K.3
  • 33
    • 0033578853 scopus 로고    scopus 로고
    • Prox1 function is required for the development of the murine lymphatic system
    • Wigle JT, Oliver G. Prox1 function is required for the development of the murine lymphatic system. Cell 1999;98:769-78.
    • (1999) Cell , vol.98 , pp. 769-778
    • Wigle, J.T.1    Oliver, G.2
  • 35
    • 18544386859 scopus 로고    scopus 로고
    • Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
    • Petrova TV, Mäkinen T, Mäkelä T, et al. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J 2002;17:4593-9.
    • (2002) EMBO J , vol.17 , pp. 4593-4599
    • Petrova, T.V.1    Mäkinen, T.2    Mäkelä, T.3
  • 36
    • 0037007216 scopus 로고    scopus 로고
    • An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
    • Wigle JT, Harvey N, Detmar M, et al. An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype. EMBO J 2002;21:1505-13.
    • (2002) EMBO J , vol.21 , pp. 1505-1513
    • Wigle, J.T.1    Harvey, N.2    Detmar, M.3
  • 37
    • 0036840138 scopus 로고    scopus 로고
    • Prox1 is a master control gene in the program specifying lymphatic endothelial fate
    • Hong Y-K, Harvey N, Noh Y-H, et al. Prox1 is a master control gene in the program specifying lymphatic endothelial fate. Dev Dyn 2002;225:351-7.
    • (2002) Dev Dyn , vol.225 , pp. 351-357
    • Hong, Y.-K.1    Harvey, N.2    Noh, Y.-H.3
  • 38
    • 0035887043 scopus 로고    scopus 로고
    • Lymphatic function, lymphangiogenesis, and cancer metastasis
    • Swartz MA, Skobe M. Lymphatic function, lymphangiogenesis, and cancer metastasis. Microsc Res Techniq 2001;55: 92-9.
    • (2001) Microsc Res Techniq , vol.55 , pp. 92-99
    • Swartz, M.A.1    Skobe, M.2
  • 39
    • 0035903290 scopus 로고    scopus 로고
    • Lymphatic vessels as targets of tumor therapy?
    • Karpanen T, Alitalo K. Lymphatic vessels as targets of tumor therapy? J Exp Med 2001;194: F37-42.
    • (2001) J Exp Med , vol.194
    • Karpanen, T.1    Alitalo, K.2
  • 41
    • 0034899437 scopus 로고    scopus 로고
    • Lymphangiogenesis and tumor metastasis: Mith or reality?
    • Pepper MS. Lymphangiogenesis and tumor metastasis: Mith or reality? Clin Cancer Res 2001;7: 462-8.
    • (2001) Clin Cancer Res , vol.7 , pp. 462-468
    • Pepper, M.S.1
  • 42
    • 0035886701 scopus 로고    scopus 로고
    • Markers of the lymphatic endothelium: In search of the holy grail?
    • Sleeman JP, Krishnan J, Kirkin V, et al. Markers of the lymphatic endothelium: In search of the holy grail? Microsc Res Techniq 2001;55: 61-9.
    • (2001) Microsc Res Techniq , vol.55 , pp. 61-69
    • Sleeman, J.P.1    Krishnan, J.2    Kirkin, V.3
  • 43
    • 0033786117 scopus 로고    scopus 로고
    • Lymphatic microvessel density in epithelial ovarian cancer: Its impact on prognosis
    • Birner P, Shindl M, Obermair A, et al. Lymphatic microvessel density in epithelial ovarian cancer: its impact on prognosis. Anticancer Res 2000;20:2981-5.
    • (2000) Anticancer Res , vol.20 , pp. 2981-2985
    • Birner, P.1    Shindl, M.2    Obermair, A.3
  • 44
    • 84873454475 scopus 로고    scopus 로고
    • Prognostic significance of intratumoral lymphangiogenesis in squamous cell carcinoma of the oral cavity: A study of the early stages [in press]
    • Muñoz-Guerra MF, Marazuela EG, Martín-Villar E, et al. Prognostic significance of intratumoral lymphangiogenesis in squamous cell carcinoma of the oral cavity: A study of the early stages [in press]. Cance.r.
    • Cancer
    • Muñoz-Guerra, M.F.1    Marazuela, E.G.2    Martín-Villar, E.3
  • 45
    • 0037430034 scopus 로고    scopus 로고
    • Prognostic significance of dysadherin expression in advanced colorectal carcinoma
    • Aoki S, Shimamura T, Shibata T, et al. Prognostic significance of dysadherin expression in advanced colorectal carcinoma. Br J Cancer 2003;88:726-32.
    • (2003) Br J Cancer , vol.88 , pp. 726-732
    • Aoki, S.1    Shimamura, T.2    Shibata, T.3
  • 46
    • 0037441643 scopus 로고    scopus 로고
    • Dysadherin overexpression in pancreatic ductal adenocarcinoma reflects tumor aggressiveness
    • Shimamura T, Sakamoto N, Ino Y, et al. Dysadherin overexpression in pancreatic ductal adenocarcinoma reflects tumor aggressiveness. Relationship to E-cadherin expression. J Clin Oncol 2003;21:659-67.
    • (2003) Relationship to E-cadherin Expression. J Clin Oncol , vol.21 , pp. 659-667
    • Shimamura, T.1    Sakamoto, N.2    Ino, Y.3
  • 48
    • 0030846295 scopus 로고    scopus 로고
    • Direct interaction of the Rho GDP dissociation inhibitor with ezrin/ radixin/moesin initiates the activation of the Rho small G protein
    • Takahashi K, Sasaki T, Mammoto A, et al. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/ radixin/moesin initiates the activation of the Rho small G protein. J Biol Chem 1997;272:23371-5.
    • (1997) J Biol Chem , vol.272 , pp. 23371-23375
    • Takahashi, K.1    Sasaki, T.2    Mammoto, A.3
  • 49
    • 0027183643 scopus 로고
    • Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells
    • Berryman M, Franck Z, Bretscher A. Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells. J Cell Sci 1993;105:1025-43.
    • (1993) J Cell Sci , vol.105 , pp. 1025-1043
    • Berryman, M.1    Franck, Z.2    Bretscher, A.3
  • 50
    • 0028206028 scopus 로고
    • Radixin is a component of hepatocyte microvilli in situ
    • Amieva MR, Wigenbus KK, Furthmayr H. Radixin is a component of hepatocyte microvilli in situ. Exp Cell Res 1994;210:140-4.
    • (1994) Exp Cell Res , vol.210 , pp. 140-144
    • Amieva, M.R.1    Wigenbus, K.K.2    Furthmayr, H.3
  • 51
    • 0033747368 scopus 로고    scopus 로고
    • Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression
    • Scholl FG, Gamallo C, Quintanilla M. Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression. Lab Invest 2000;80:1749-59.
    • (2000) Lab Invest , vol.80 , pp. 1749-1759
    • Scholl, F.G.1    Gamallo, C.2    Quintanilla, M.3
  • 53
    • 0035991930 scopus 로고    scopus 로고
    • Cloning and expression of the mouse glomerular podoplanin homologue gp38p
    • Boucherot K, Schreiber R, Pavenstadt H, et al. Cloning and expression of the mouse glomerular podoplanin homologue gp38p. Nephrol Dial Transplant 2002;17:978-84.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 978-984
    • Boucherot, K.1    Schreiber, R.2    Pavenstadt, H.3
  • 54
    • 0034659690 scopus 로고    scopus 로고
    • Molecular cloning and characterization of antigens expressed on rat tumor vascular endothelial cells
    • Taniguchi K, Harada N, Ohizumi I, et al. Molecular cloning and characterization of antigens expressed on rat tumor vascular endothelial cells. Int J Cancer 2000;86: 799-805.
    • (2000) Int J Cancer , vol.86 , pp. 799-805
    • Taniguchi, K.1    Harada, N.2    Ohizumi, I.3


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