Exogenous melatonin abolishes mechanicalallodynia but not thermal hyperalgesia in neuropathic pain. The role of the opioid system and benzodiazepine-gabaergic mechanism

Journal of Physiology and Pharmacology

Volumn 63, Issue 6, 2012, Pages 641-647

  Zurowski, D ^a   Nowak, L ^a   Machowska, A ^a   Wordliczek, J ^a   Thor, P J ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Allodynia; GABA receptors; Hyperalgesia; Melatonin; Melatonin receptors; Neuropathic pain; Opioid system

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; FLUMAZENIL; LUZINDOLE; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; NALOXONE; NARCOTIC ANALGESIC AGENT; PICROTOXIN; PRAZOSIN;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; GABAERGIC SYSTEM; HYPERALGESIA; LATENT PERIOD; MALE; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; PROTEIN PROTEIN INTERACTION; RAT; STIMULUS RESPONSE; THERMAL STIMULATION;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; GABA-A RECEPTOR ANTAGONISTS; HOT TEMPERATURE; HYPERALGESIA; MALE; MELATONIN; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; PAIN PERCEPTION; PAIN THRESHOLD; PRESSURE; RATS; RATS, WISTAR; RECEPTORS, GABA-A; RECEPTORS, MELATONIN; RECEPTORS, OPIOID; SCIATIC NEUROPATHY; SCIATICA; TIME FACTORS;

EID: 84873433898     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

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