메뉴 건너뛰기




Volumn 43, Issue 2, 2013, Pages 116-124

Current therapeutic strategy for multiple myeloma

Author keywords

ASCT; Multiple myeloma; Renal insufficiency; SPM

Indexed keywords

BENCE JONES PROTEIN; BISPHOSPHONIC ACID DERIVATIVE; BORTEZOMIB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DENOSUMAB; DEXAMETHASONE; DOXORUBICIN; GAMMA INTERFERON; GLUCOCORTICOID; INTERLEUKIN 2; LENALIDOMIDE; M PROTEIN; MELPHALAN; PAMIDRONIC ACID; PREDNISOLONE; THALIDOMIDE; UBIQUITIN PROTEIN LIGASE E3; VINCRISTINE; ZOLEDRONIC ACID;

EID: 84873433536     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hys215     Document Type: Article
Times cited : (33)

References (57)
  • 1
    • 37049231954 scopus 로고
    • Myeloma proteins and the clinical response to Melphalan Therapy
    • de Bergsagel DE, Migliore PJ, Griffith KM. Myeloma proteins and the clinical response to Melphalan Therapy. Science 1965;148:376-7.
    • (1965) Science , vol.148 , pp. 376-377
    • de Bergsagel, D.E.1    Migliore, P.J.2    Griffith, K.M.3
  • 2
    • 0014098383 scopus 로고
    • Intermittent high dose prednisone therapy for multiple myeloma
    • Salmon SC, Shadduck RK, Schilling A. Intermittent high dose prednisone therapy for multiple myeloma. Cancer Chemother Rep 1967;51:179-87.
    • (1967) Cancer Chemother Rep , vol.51 , pp. 179-187
    • Salmon, S.C.1    Shadduck, R.K.2    Schilling, A.3
  • 3
    • 0014661330 scopus 로고
    • Treatment for multiple myeloma. Combination chemotherapy with different melphalan dose regimens
    • Alexanian R, Haut A, Khan AU, et al. Treatment for multiple myeloma. Combination chemotherapy with different melphalan dose regimens. JAMA 1969;208:1680-85.
    • (1969) JAMA , vol.208 , pp. 1680-1685
    • Alexanian, R.1    Haut, A.2    Khan, A.U.3
  • 4
    • 0037148921 scopus 로고    scopus 로고
    • A long-term study of prognosis in monoclonal gammopathy of undetermined significance
    • Kyle RA, Therneau TM, Rajkumar SV, et al. A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med 2002;346:564-9.
    • (2002) N Engl J Med , vol.346 , pp. 564-569
    • Kyle, R.A.1    Therneau, T.M.2    Rajkumar, S.V.3
  • 5
    • 41949130070 scopus 로고    scopus 로고
    • Improved survival in multiple myeloma and the impact of novel therapies
    • Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008;111:2516-20.
    • (2008) Blood , vol.111 , pp. 2516-2520
    • Kumar, S.K.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 7
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson PG, Sonneveld P, Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005;352:2487-98.
    • (2005) N Engl J Med , vol.352 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 8
    • 78049488759 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial
    • Harousseau JL, Attal M, Avet-Loiseau H, et al. Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol 2010;28:4621-9.
    • (2010) J Clin Oncol , vol.28 , pp. 4621-4629
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 9
    • 75149147388 scopus 로고    scopus 로고
    • Extended follow-up of a phase 2 trial of bortezomib alone and in combination with dexamethasone for the frontline treatment of multiple myeloma
    • Jagannath S, Durie BG, Wolf JL, et al. Extended follow-up of a phase 2 trial of bortezomib alone and in combination with dexamethasone for the frontline treatment of multiple myeloma. Br J Haematol 2009;146:619-26.
    • (2009) Br J Haematol , vol.146 , pp. 619-626
    • Jagannath, S.1    Durie, B.G.2    Wolf, J.L.3
  • 10
    • 84865171981 scopus 로고    scopus 로고
    • Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial
    • Sonneveld P, Schmidt-Wolf IG, van der Holt B, et al. Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial. J Clin Oncol 2012;30:2946-55.
    • (2012) J Clin Oncol , vol.30 , pp. 2946-2955
    • Sonneveld, P.1    Schmidt-Wolf, I.G.2    van der Holt, B.3
  • 11
    • 77649092410 scopus 로고    scopus 로고
    • Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma
    • Jakubowiak AJ, Kendall T, Al-Zoubi A, et al. Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma. J Clin Oncol 2009;27:5015-22.
    • (2009) J Clin Oncol , vol.27 , pp. 5015-5022
    • Jakubowiak, A.J.1    Kendall, T.2    Al-Zoubi, A.3
  • 12
    • 67650882695 scopus 로고    scopus 로고
    • Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial
    • Reeder CB, Reece DE, Kukreti V, et al. Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial. Leukemia 2009;23:1337-41.
    • (2009) Leukemia , vol.23 , pp. 1337-1341
    • Reeder, C.B.1    Reece, D.E.2    Kukreti, V.3
  • 13
    • 84860907057 scopus 로고    scopus 로고
    • Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
    • Kumar S, Flinn I, Richardson PG, et al. Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma. Blood 2012;119:4375-82.
    • (2012) Blood , vol.119 , pp. 4375-4382
    • Kumar, S.1    Flinn, I.2    Richardson, P.G.3
  • 14
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva NK, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906-17.
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 15
    • 80051570906 scopus 로고    scopus 로고
    • Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials
    • Fayers PM, Palumbo A, Hulin C, et al. Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials. Blood 2011;118:1239-47.
    • (2011) Blood , vol.118 , pp. 1239-1247
    • Fayers, P.M.1    Palumbo, A.2    Hulin, C.3
  • 16
    • 84873420145 scopus 로고    scopus 로고
    • Continued Overall Survival Benefit after 5 years' Follow-up with Bortezomib-melphalan-prednisone (VMP) Versus melphalan-prednisone (MP) in Patients with Previously Untreated Multiple Myeloma, and no Increased Risk of Second Primary Malignancies: Final Results of the Phase 3 VISTA Trial. 53rd Annual Meeting of the American Society of Hematology Abstract 476
    • San Miguel JF. Continued Overall Survival Benefit after 5 years' Follow-up with Bortezomib-melphalan-prednisone (VMP) Versus melphalan-prednisone (MP) in Patients with Previously Untreated Multiple Myeloma, and no Increased Risk of Second Primary Malignancies: Final Results of the Phase 3 VISTA Trial. 53rd Annual Meeting of the American Society of Hematology 2011. Abstract 476.
    • (2011)
    • San Miguel, J.F.1
  • 17
    • 84891729494 scopus 로고    scopus 로고
    • A phase I/II study of VMP as initial treatment for multiple myeloma in Japan
    • Iida S, Ando K, Suzuki K, et al. A phase I/II study of VMP as initial treatment for multiple myeloma in Japan. Rinsho Ketsueki 2012;53:1122.
    • (2012) Rinsho Ketsueki , vol.53 , pp. 1122
    • Iida, S.1    Ando, K.2    Suzuki, K.3
  • 18
    • 51249083648 scopus 로고    scopus 로고
    • The relationship between quality of response and clinical benefit for patients treated on the bortezomib arm of the international, randomized, phase 3 APEX trial in relapsed multiple myeloma
    • Niesvizky R, Richardson PG, Rajkumar SV, et al. The relationship between quality of response and clinical benefit for patients treated on the bortezomib arm of the international, randomized, phase 3 APEX trial in relapsed multiple myeloma. Br J Haematol 2008;143:46-53.
    • (2008) Br J Haematol , vol.143 , pp. 46-53
    • Niesvizky, R.1    Richardson, P.G.2    Rajkumar, S.V.3
  • 19
    • 70350433797 scopus 로고    scopus 로고
    • The role of complete response in multiple myeloma
    • Harousseau JL, Attal M, Avet-Loiseau H. The role of complete response in multiple myeloma. Blood 2009;114:3139-46.
    • (2009) Blood , vol.114 , pp. 3139-3146
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 20
    • 77956259865 scopus 로고    scopus 로고
    • Importance of achieving a complete response in multiple myeloma, and the impact of novel agents
    • Chanan-Khan AA, Giralt S. Importance of achieving a complete response in multiple myeloma, and the impact of novel agents. J Clin Oncol 2010;28:2612-24.
    • (2010) J Clin Oncol , vol.28 , pp. 2612-2624
    • Chanan-Khan, A.A.1    Giralt, S.2
  • 21
    • 79955461011 scopus 로고    scopus 로고
    • Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomized, phase 3, non-inferiority study
    • Moreau P, Pylypenko H, Grosicki S, et al. Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomized, phase 3, non-inferiority study. Lancet Oncol 2011;12:431-40.
    • (2011) Lancet Oncol , vol.12 , pp. 431-440
    • Moreau, P.1    Pylypenko, H.2    Grosicki, S.3
  • 22
    • 57349171505 scopus 로고    scopus 로고
    • Prospective comparison of subcutaneous to intravenous administration of bortezomib in patients with multiple myeloma
    • Moreau P, Coiteux V, Hulin C, et al. Prospective comparison of subcutaneous to intravenous administration of bortezomib in patients with multiple myeloma. Haematologica 2008;93:1908-11.
    • (2008) Haematologica , vol.93 , pp. 1908-1911
    • Moreau, P.1    Coiteux, V.2    Hulin, C.3
  • 23
    • 84857767379 scopus 로고    scopus 로고
    • Cyclophosphamide, thalidomide, and dexamethasone as induction therapy for newly diagnosed multiple myeloma patients destined for autologous stem-cell transplantation: MRC Myeloma IX randomized trial results
    • Morgan GJ, Davies FE, Gregory WM, et al. Cyclophosphamide, thalidomide, and dexamethasone as induction therapy for newly diagnosed multiple myeloma patients destined for autologous stem-cell transplantation: MRC Myeloma IX randomized trial results. Haematologica 2012;97:442-50.
    • (2012) Haematologica , vol.97 , pp. 442-450
    • Morgan, G.J.1    Davies, F.E.2    Gregory, W.M.3
  • 24
    • 80051557449 scopus 로고    scopus 로고
    • Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation
    • Morgan GJ, Davies FE, Gregory WM, et al. Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation. Blood 2011;118:1231-8.
    • (2011) Blood , vol.118 , pp. 1231-1238
    • Morgan, G.J.1    Davies, F.E.2    Gregory, W.M.3
  • 25
    • 84863576232 scopus 로고    scopus 로고
    • Bortezomibthalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy following autologous hematopoietic stem-cell transplantation in patients with newly diagnosed multiple myeloma
    • Cavo M, Pantani L, Petrucci MT, et al. Bortezomibthalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy following autologous hematopoietic stem-cell transplantation in patients with newly diagnosed multiple myeloma. Blood 2012;120:9-19.
    • (2012) Blood , vol.120 , pp. 9-19
    • Cavo, M.1    Pantani, L.2    Petrucci, M.T.3
  • 26
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study
    • Cavo M, Tacchetti P, Patriarca F, et al. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet 2010;376:2075-85.
    • (2010) Lancet , vol.376 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 27
    • 82155178738 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma
    • Moreau P, Avet-Loiseau H, Facon T, et al. Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma. Blood 2011;118:5752-8.
    • (2011) Blood , vol.118 , pp. 5752-5758
    • Moreau, P.1    Avet-Loiseau, H.2    Facon, T.3
  • 28
    • 78649707335 scopus 로고    scopus 로고
    • Lenalidomide mode of action: linking bench and clinical findings
    • Davies F, Baz R. Lenalidomide mode of action: linking bench and clinical findings. Blood Rev. 2010;(Suppl. 1):S13-9.
    • (2010) Blood Rev , Issue.SUPPL. 1
    • Davies, F.1    Baz, R.2
  • 29
    • 80855156719 scopus 로고    scopus 로고
    • Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
    • Zhu YX, Braggio E, Shi CX, et al. Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide. Blood 2011;118:4771-9.
    • (2011) Blood , vol.118 , pp. 4771-4779
    • Zhu, Y.X.1    Braggio, E.2    Shi, C.X.3
  • 30
    • 84869082150 scopus 로고    scopus 로고
    • Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
    • Lopez-Girona A, Mendy D, Ito T, et al. Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide. Leukemia 2012;26:2326-35.
    • (2012) Leukemia , vol.26 , pp. 2326-2335
    • Lopez-Girona, A.1    Mendy, D.2    Ito, T.3
  • 31
    • 79960220394 scopus 로고    scopus 로고
    • Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response
    • Lopez-Girona A, Heintel D, Zhang LH, et al. Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response. Br J Haematol 2011;154:325-36.
    • (2011) Br J Haematol , vol.154 , pp. 325-336
    • Lopez-Girona, A.1    Heintel, D.2    Zhang, L.H.3
  • 32
    • 36349023319 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma
    • Dimopoulos M, Spencer A, Attal M, et al. Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma. N Engl J Med 2007;357:2123-32.
    • (2007) N Engl J Med , vol.357 , pp. 2123-2132
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 33
    • 36349010285 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med 2007;357:2133-42.
    • (2007) N Engl J Med , vol.357 , pp. 2133-2142
    • Weber, D.M.1    Chen, C.2    Niesvizky, R.3
  • 34
    • 70450230539 scopus 로고    scopus 로고
    • Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma
    • Dimopoulos MA, Chen C, Spencer A, et al. Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma. Leukemia 2009;23:2147-52.
    • (2009) Leukemia , vol.23 , pp. 2147-2152
    • Dimopoulos, M.A.1    Chen, C.2    Spencer, A.3
  • 35
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial
    • Rajkumar SV, Jacobus S, Callander NS, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol 2010;11:29-37.
    • (2010) Lancet Oncol , vol.11 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3
  • 36
    • 69449108135 scopus 로고    scopus 로고
    • The use of bisphosphonates in multiple myeloma: recommendations of an expert panel on behalf of the European Myeloma Network
    • Terpos E, Sezer O, Croucher PI, et al. The use of bisphosphonates in multiple myeloma: recommendations of an expert panel on behalf of the European Myeloma Network. Ann Oncol 2009;20:1303-17.
    • (2009) Ann Oncol , vol.20 , pp. 1303-1317
    • Terpos, E.1    Sezer, O.2    Croucher, P.I.3
  • 37
    • 73449128342 scopus 로고    scopus 로고
    • The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation
    • Guenther A, Gordon S, Tiemann M, et al. The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation. Int J Cancer 2010;126:239-46.
    • (2010) Int J Cancer , vol.126 , pp. 239-246
    • Guenther, A.1    Gordon, S.2    Tiemann, M.3
  • 38
    • 33845912677 scopus 로고    scopus 로고
    • Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease
    • Dunstan C, Felsenberg D, Seibel MJ. Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease. Nat Clin Pract Oncol 2007;4:42-55.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 42-55
    • Dunstan, C.1    Felsenberg, D.2    Seibel, M.J.3
  • 39
  • 40
    • 33751164196 scopus 로고    scopus 로고
    • Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
    • Attal M, Harousseau JL, Leyvraz S, et al. Maintenance therapy with thalidomide improves survival in patients with multiple myeloma. Blood 2006;108:3289-94.
    • (2006) Blood , vol.108 , pp. 3289-3294
    • Attal, M.1    Harousseau, J.L.2    Leyvraz, S.3
  • 41
    • 64649083365 scopus 로고    scopus 로고
    • Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure
    • Spencer A, Prince HM, Roberts AW, et al. Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure. J Clin Oncol 2009;27:1788-93.
    • (2009) J Clin Oncol , vol.27 , pp. 1788-1793
    • Spencer, A.1    Prince, H.M.2    Roberts, A.W.3
  • 42
    • 84868343119 scopus 로고    scopus 로고
    • Discovery research on the effects of giving continuity to the administration of bortezomib in maintenance therapy to target of relapsed and refractory multiple myeloma
    • Suzuki K. Discovery research on the effects of giving continuity to the administration of bortezomib in maintenance therapy to target of relapsed and refractory multiple myeloma. J New Rem Clin 2012;61:1259-69.
    • (2012) J New Rem Clin , vol.61 , pp. 1259-1269
    • Suzuki, K.1
  • 43
    • 77950644007 scopus 로고    scopus 로고
    • Dexamethasone synergizes with lenalidomide to inhibit multiple myeloma tumor growth, but reduces lenalidomide-induced immunomodulation of T and NK cell function
    • Gandhi AK, Kang J, Capone L, et al. Dexamethasone synergizes with lenalidomide to inhibit multiple myeloma tumor growth, but reduces lenalidomide-induced immunomodulation of T and NK cell function. Curr Cancer Drug Targets 2010;10:155-67.
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 155-167
    • Gandhi, A.K.1    Kang, J.2    Capone, L.3
  • 44
    • 84860709392 scopus 로고    scopus 로고
    • Lenalidomide maintenance after stem-cell transplantation for multiple myeloma
    • Attal M, Lauwers-Cances V, Marit G, et al. Lenalidomide maintenance after stem-cell transplantation for multiple myeloma. N Engl J Med 2012;366:1782-91.
    • (2012) N Engl J Med , vol.366 , pp. 1782-1791
    • Attal, M.1    Lauwers-Cances, V.2    Marit, G.3
  • 45
    • 84860741191 scopus 로고    scopus 로고
    • Lenalidomide after stem-cell transplantation for multiple myeloma
    • McCarthy PL, Owzar K, Hofmeister CC, et al. Lenalidomide after stem-cell transplantation for multiple myeloma. N Engl J Med. 2012;366:1770-81.
    • (2012) N Engl J Med , vol.366 , pp. 1770-1781
    • McCarthy, P.L.1    Owzar, K.2    Hofmeister, C.C.3
  • 46
    • 84860744403 scopus 로고    scopus 로고
    • Continuous lenalidomide treatment for newly diagnosed multiple myeloma
    • Palumbo A, Hajek R, Delforge M, et al. Continuous lenalidomide treatment for newly diagnosed multiple myeloma. N Engl J Med 2012;366:1759-69.
    • (2012) N Engl J Med , vol.366 , pp. 1759-1769
    • Palumbo, A.1    Hajek, R.2    Delforge, M.3
  • 47
    • 84860741220 scopus 로고    scopus 로고
    • Lenalidomide in myeloma-a high-maintenance friend
    • Badros AZ. Lenalidomide in myeloma-a high-maintenance friend. N Engl J Med 2012;366:1836-8.
    • (2012) N Engl J Med , vol.366 , pp. 1836-1838
    • Badros, A.Z.1
  • 48
    • 84858858229 scopus 로고    scopus 로고
    • A review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomide
    • Dimopoulos MA, Richardson PG, Brandenburg N, et al. A review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomide. Blood 2012;119:2764-7.
    • (2012) Blood , vol.119 , pp. 2764-2767
    • Dimopoulos, M.A.1    Richardson, P.G.2    Brandenburg, N.3
  • 49
    • 84876407057 scopus 로고    scopus 로고
    • Tandem autologous vs autologous plus reduced intensity allogeneic transplantation in the upfront management of multiple myeloma: meta-analysis of trials with biological assignment
    • doi:10.1038/ bmt.2012.173
    • Armeson KE, Hill EG, Costa LJ. Tandem autologous vs autologous plus reduced intensity allogeneic transplantation in the upfront management of multiple myeloma: meta-analysis of trials with biological assignment. Bone Marrow Transplant 2012; doi:10.1038/ bmt.2012.173.
    • (2012) Bone Marrow Transplant
    • Armeson, K.E.1    Hill, E.G.2    Costa, L.J.3
  • 50
    • 84860749854 scopus 로고    scopus 로고
    • Effective response with bortezomib retreatment in relapsed multiple myeloma-a multicentre retrospective survey in Switzerland
    • Taverna C, Voegeli J, Trojan A, et al. Effective response with bortezomib retreatment in relapsed multiple myeloma-a multicentre retrospective survey in Switzerland. Swiss Med Wkly 2012;142:w13562.
    • (2012) Swiss Med Wkly , vol.142
    • Taverna, C.1    Voegeli, J.2    Trojan, A.3
  • 53
    • 84891731241 scopus 로고    scopus 로고
    • Therapy-related myelodysplastic syndrome/acute myeloid leukemia in patients with multiple myeloma
    • Abe Y, Miyazaki K, Suzuki K, et al. Therapy-related myelodysplastic syndrome/acute myeloid leukemia in patients with multiple myeloma. Rinsho Ketsueki 2012;52:1264.
    • (2012) Rinsho Ketsueki , vol.52 , pp. 1264
    • Abe, Y.1    Miyazaki, K.2    Suzuki, K.3
  • 54
    • 0032575885 scopus 로고    scopus 로고
    • Renal failure in multiple myeloma: presenting features and predictors of outcome in 94 patients from a single institution
    • Blade J, Fernández-Llama P, Bosch F, et al. Renal failure in multiple myeloma: presenting features and predictors of outcome in 94 patients from a single institution. Arch Intern Med 1998;158:1889-93.
    • (1998) Arch Intern Med , vol.158 , pp. 1889-1893
    • Blade, J.1    Fernández-Llama, P.2    Bosch, F.3
  • 55
    • 77955985354 scopus 로고    scopus 로고
    • Reversibility of renal failure in newly diagnosed patients with multiple myeloma and the role of novel agents
    • Roussou M, Kastritis E, Christoulas D, et al. Reversibility of renal failure in newly diagnosed patients with multiple myeloma and the role of novel agents. Leuk Res 2010;34:1395-7.
    • (2010) Leuk Res , vol.34 , pp. 1395-1397
    • Roussou, M.1    Kastritis, E.2    Christoulas, D.3
  • 56
    • 80055066620 scopus 로고    scopus 로고
    • Personalized therapy in MM according to patient age and vulnerability: a report of the European Myeloma Network (EMN)
    • Palumbo A, Bringhen S, Ludwig H, et al. Personalized therapy in MM according to patient age and vulnerability: a report of the European Myeloma Network (EMN). Blood 2011;118:4519-29.
    • (2011) Blood , vol.118 , pp. 4519-4529
    • Palumbo, A.1    Bringhen, S.2    Ludwig, H.3
  • 57
    • 67650032911 scopus 로고    scopus 로고
    • Clinical and immunological evaluation of zoledronate-activated V9 T-cell-based immunotherapy for patients with multiple myeloma
    • Abe Y, Muto M, Nieda M, et al. Clinical and immunological evaluation of zoledronate-activated V9 T-cell-based immunotherapy for patients with multiple myeloma. Exp Hematol 2009;37:956-968.
    • (2009) Exp Hematol , vol.37 , pp. 956-968
    • Abe, Y.1    Muto, M.2    Nieda, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.