메뉴 건너뛰기




Volumn 48, Issue 4, 2013, Pages 562-567

Tandem autologous vs autologous plus reduced intensity allogeneic transplantation in the upfront management of multiple myeloma: Meta-analysis of trials with biological assignment

Author keywords

allogeneic transplantation; autologous transplantation; HLA; meta analysis; multiple myeloma

Indexed keywords

BUSULFAN; CARMUSTINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; ETOPOSIDE; FLUDARABINE; MELPHALAN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY;

EID: 84876407057     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2012.173     Document Type: Article
Times cited : (58)

References (37)
  • 1
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, Stoppa AM, Sotto JJ, Fuzibet JG, Rossi JF et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996; 335: 91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3    Sotto, J.J.4    Fuzibet, J.G.5    Rossi, J.F.6
  • 2
    • 0032211193 scopus 로고    scopus 로고
    • High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial
    • Fermand JP, Ravaud P, Chevret S, Divine M, Leblond V, Belanger C et al. High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial. Blood 1998; 92: 3131-3136.
    • (1998) Blood , vol.92 , pp. 3131-3136
    • Fermand, J.P.1    Ravaud, P.2    Chevret, S.3    Divine, M.4    Leblond, V.5    Belanger, C.6
  • 3
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE, Owen RG, Bell SE, Hawkins K et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348: 1875-1883.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3    Owen, R.G.4    Bell, S.E.5    Hawkins, K.6
  • 4
    • 28444494386 scopus 로고    scopus 로고
    • High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: Long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA
    • Blade J, Rosinol L, Sureda A, Ribera JM, Diaz-Mediavilla J, Garcia-Larana J et al. High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA. Blood 2005; 106: 3755-3759.
    • (2005) Blood , vol.106 , pp. 3755-3759
    • Blade, J.1    Rosinol, L.2    Sureda, A.3    Ribera, J.M.4    Diaz-Mediavilla, J.5    Garcia-Larana, J.6
  • 5
    • 33644920953 scopus 로고    scopus 로고
    • Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: Final results of phase III US Intergroup Trial S9321
    • Barlogie B, Kyle RA, Anderson KC, Greipp PR, Lazarus HM, Hurd DD et al. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321. J Clin Oncol 2006; 24: 929-936.
    • (2006) J Clin Oncol , vol.24 , pp. 929-936
    • Barlogie, B.1    Kyle, R.A.2    Anderson, K.C.3    Greipp, P.R.4    Lazarus, H.M.5    Hurd, D.D.6
  • 6
  • 7
    • 34347260711 scopus 로고    scopus 로고
    • Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 clinical study
    • Cavo M, Tosi P, Zamagni E, Cellini C, Tacchetti P, Patriarca F et al. Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 clinical study. J Clin Oncol 2007; 25: 2434-2441.
    • (2007) J Clin Oncol , vol.25 , pp. 2434-2441
    • Cavo, M.1    Tosi, P.2    Zamagni, E.3    Cellini, C.4    Tacchetti, P.5    Patriarca, F.6
  • 9
    • 0033844816 scopus 로고    scopus 로고
    • Donor lymphocyte infusions for relapsed multiple myeloma after allogeneic stem-cell transplantation: Predictive factors for response and long-term outcome
    • Lokhorst HM, Schattenberg A, Cornelissen JJ, van Oers MH, Fibbe W, Russell I et al. Donor lymphocyte infusions for relapsed multiple myeloma after allogeneic stem-cell transplantation: predictive factors for response and long-term outcome. J Clin Oncol 2000; 18: 3031-3037.
    • (2000) J Clin Oncol , vol.18 , pp. 3031-3037
    • Lokhorst, H.M.1    Schattenberg, A.2    Cornelissen, J.J.3    Van Oers, M.H.4    Fibbe, W.5    Russell, I.6
  • 10
    • 2542448169 scopus 로고    scopus 로고
    • The occurrence of graft-versus-host disease is the major predictive factor for response to donor lymphocyte infusions in multiple myeloma
    • Lokhorst HM, Wu K, Verdonck LF, Laterveer LL, van de Donk NW, van Oers MH et al. The occurrence of graft-versus-host disease is the major predictive factor for response to donor lymphocyte infusions in multiple myeloma. Blood 2004; 103: 4362-4364.
    • (2004) Blood , vol.103 , pp. 4362-4364
    • Lokhorst, H.M.1    Wu, K.2    Verdonck, L.F.3    Laterveer, L.L.4    Van De Donk, N.W.5    Van Oers, M.H.6
  • 11
    • 0026070258 scopus 로고
    • Allogeneic bone marrow transplantation in multiple myeloma. European Group for Bone Marrow Transplantation
    • Gahrton G, Tura S, Ljungman P, Belanger C, Brandt L, Cavo M et al. Allogeneic bone marrow transplantation in multiple myeloma. European Group for Bone Marrow Transplantation. N Engl J Med 1991; 325: 1267-1273.
    • (1991) N Engl J Med , vol.325 , pp. 1267-1273
    • Gahrton, G.1    Tura, S.2    Ljungman, P.3    Belanger, C.4    Brandt, L.5    Cavo, M.6
  • 12
    • 17744364050 scopus 로고    scopus 로고
    • Progress in allogenic bone marrow and peripheral blood stem cell transplantation for multiple myeloma: A comparison between transplants performed 1983-93 and 1994-8 at European Group for Blood and Marrow Transplantation centres
    • Gahrton G, Svensson H, Cavo M, Apperly J, Bacigalupo A, Bjorkstrand B et al. Progress in allogenic bone marrow and peripheral blood stem cell transplantation for multiple myeloma: a comparison between transplants performed 1983-93 and 1994-8 at European Group for Blood and Marrow Transplantation centres. Br J Haematol 2001; 113: 209-216.
    • (2001) Br J Haematol , vol.113 , pp. 209-216
    • Gahrton, G.1    Svensson, H.2    Cavo, M.3    Apperly, J.4    Bacigalupo, A.5    Bjorkstrand, B.6
  • 13
    • 0036682491 scopus 로고    scopus 로고
    • Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma
    • Kroger N, Schwerdtfeger R, Kiehl M, Sayer HG, Renges H, Zabelina T et al. Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma. Blood 2002; 100: 755-760.
    • (2002) Blood , vol.100 , pp. 755-760
    • Kroger, N.1    Schwerdtfeger, R.2    Kiehl, M.3    Sayer, H.G.4    Renges, H.5    Zabelina, T.6
  • 14
    • 0142152420 scopus 로고    scopus 로고
    • Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma
    • Maloney DG, Molina AJ, Sahebi F, Stockerl-Goldstein KE, Sandmaier BM, Bensinger W et al. Allografting with nonmyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma. Blood 2003; 102: 3447-3454.
    • (2003) Blood , vol.102 , pp. 3447-3454
    • Maloney, D.G.1    Molina, A.J.2    Sahebi, F.3    Stockerl-Goldstein, K.E.4    Sandmaier, B.M.5    Bensinger, W.6
  • 15
    • 59349093509 scopus 로고    scopus 로고
    • Reduced-intensity conditioning regimen workshop: Defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research
    • Giralt S, Ballen K, Rizzo D, Bacigalupo A, Horowitz M, Pasquini M et al. Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the center for international blood and marrow transplant research. Biol Blood Marrow Transplant 2009; 15: 367-369.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 367-369
    • Giralt, S.1    Ballen, K.2    Rizzo, D.3    Bacigalupo, A.4    Horowitz, M.5    Pasquini, M.6
  • 16
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 1998; 17: 2815-2834.
    • (1998) Stat Med , vol.17 , pp. 2815-2834
    • Parmar, M.K.1    Torri, V.2    Stewart, L.3
  • 17
    • 80051642093 scopus 로고    scopus 로고
    • Tandem autologous/reduced-intensity conditioning allogeneic stem-cell transplantation versus autologous transplantation in myeloma: Long-term follow-up
    • Bjorkstrand B, Iacobelli S, Hegenbart U, Gruber A, Greinix H, Volin L et al. Tandem autologous/reduced-intensity conditioning allogeneic stem-cell transplantation versus autologous transplantation in myeloma: long-term follow-up. J Clin Oncol 2011; 29: 3016-3022.
    • (2011) J Clin Oncol , vol.29 , pp. 3016-3022
    • Bjorkstrand, B.1    Iacobelli, S.2    Hegenbart, U.3    Gruber, A.4    Greinix, H.5    Volin, L.6
  • 18
    • 41049093347 scopus 로고
    • The combination of estimates from different experiments
    • Cochran WG. The combination of estimates from different experiments. Biometrics 1954; 10: 101-129.
    • (1954) Biometrics , vol.10 , pp. 101-129
    • Cochran, W.G.1
  • 19
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 20
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 25
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009; 339: b2535.
    • (2009) BMJ , vol.339
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 27
    • 79959243080 scopus 로고    scopus 로고
    • Long-term follow-up of a comparison of nonmyeloablative allografting with autografting for newly diagnosed myeloma
    • Giaccone L, Storer B, Patriarca F, Rotta M, Sorasio R, Allione B et al. Long-term follow-up of a comparison of nonmyeloablative allografting with autografting for newly diagnosed myeloma. Blood 2011; 117: 6721-6727.
    • (2011) Blood , vol.117 , pp. 6721-6727
    • Giaccone, L.1    Storer, B.2    Patriarca, F.3    Rotta, M.4    Sorasio, R.5    Allione, B.6
  • 28
    • 78049284531 scopus 로고    scopus 로고
    • Allogeneic stem cell transplant versus tandem high-dose melphalan for front-line treatment of deletion 13q14 myeloma-an interim analysis of the German DSMM v Trial
    • Knop S, Liebisch P, Hebart H, Holler E, Engelhardt M, Bargou RC et al. Allogeneic stem cell transplant versus tandem high-dose melphalan for front-line treatment of deletion 13q14 myeloma-an interim analysis of the German DSMM V Trial. ASH Annu Meet Abstr 2009; 114: 51.
    • (2009) ASH Annu Meet Abstr , vol.114 , pp. 51
    • Knop, S.1    Liebisch, P.2    Hebart, H.3    Holler, E.4    Engelhardt, M.5    Bargou, R.C.6
  • 29
    • 82555179157 scopus 로고    scopus 로고
    • Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): A phase 3 biological assignment trial
    • Krishnan A, Pasquini MC, Logan B, Stadtmauer EA, Vesole DH, Alyea 3rd E et al. Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): a phase 3 biological assignment trial. Lancet Oncol 2011; 12: 1195-1203.
    • (2011) Lancet Oncol , vol.12 , pp. 1195-1203
    • Krishnan, A.1    Pasquini, M.C.2    Logan, B.3    Stadtmauer, E.A.4    Vesole, D.H.5    Alyea Iii., E.6
  • 30
    • 55749099328 scopus 로고    scopus 로고
    • A prospective PETHEMA study of tandem autologous transplantation versus auto-graft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma
    • Rosinol L, Perez-Simon JA, Sureda A, de la Rubia J, de Arriba F, Lahuerta JJ et al. A prospective PETHEMA study of tandem autologous transplantation versus auto-graft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma. Blood 2008; 112: 3591-3593.
    • (2008) Blood , vol.112 , pp. 3591-3593
    • Rosinol, L.1    Perez-Simon, J.A.2    Sureda, A.3    De La Rubia, J.4    De Arriba, F.5    Lahuerta, J.J.6
  • 31
    • 55749090051 scopus 로고    scopus 로고
    • Long-term follow-up results of IFM99-03 and IFM99-04 trials comparing nonmyeloablative allotransplantation with autologous transplantation in high-risk de novo multiple myeloma
    • Moreau P, Garban F, Attal M, Michallet M, Marit G, Hulin C et al. Long-term follow-up results of IFM99-03 and IFM99-04 trials comparing nonmyeloablative allotransplantation with autologous transplantation in high-risk de novo multiple myeloma. Blood 2008; 112: 3914-3915.
    • (2008) Blood , vol.112 , pp. 3914-3915
    • Moreau, P.1    Garban, F.2    Attal, M.3    Michallet, M.4    Marit, G.5    Hulin, C.6
  • 32
    • 30144439125 scopus 로고    scopus 로고
    • Tandem autologous stem cell transplantation in high-risk de novo multiple myeloma: Final results of the prospective and randomized IFM 99-04 protocol
    • Moreau P, Hullin C, Garban F, Yakoub-Agha I, Benboubker L, Attal M et al. Tandem autologous stem cell transplantation in high-risk de novo multiple myeloma: final results of the prospective and randomized IFM 99-04 protocol. Blood 2006; 107: 397-403.
    • (2006) Blood , vol.107 , pp. 397-403
    • Moreau, P.1    Hullin, C.2    Garban, F.3    Yakoub-Agha, I.4    Benboubker, L.5    Attal, M.6
  • 33
    • 33646401089 scopus 로고    scopus 로고
    • Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma
    • Garban F, Attal M, Michallet M, Hulin C, Bourhis JH, Yakoub-Agha I et al. Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma. Blood 2006; 107: 3474-3480.
    • (2006) Blood , vol.107 , pp. 3474-3480
    • Garban, F.1    Attal, M.2    Michallet, M.3    Hulin, C.4    Bourhis, J.H.5    Yakoub-Agha, I.6
  • 34
    • 70350433797 scopus 로고    scopus 로고
    • The role of complete response in multiple myeloma
    • Harousseau JL, Attal M, Avet-Loiseau H. The role of complete response in multiple myeloma. Blood 2009; 114: 3139-3146.
    • (2009) Blood , vol.114 , pp. 3139-3146
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 35
    • 84863520725 scopus 로고    scopus 로고
    • Donor versus no donor comparison of newly diagnosed myeloma patients included in the HOVON 50 multiple myeloma study
    • Lokhorst HM, van der Holt B, Cornelissen JJ, Kersten MJ, van Oers M, Raymakers R et al. Donor versus no donor comparison of newly diagnosed myeloma patients included in the HOVON 50 multiple myeloma study. Blood 2012; 119: 6219-6225.
    • (2012) Blood , vol.119 , pp. 6219-6225
    • Lokhorst, H.M.1    Van Der Holt, B.2    Cornelissen, J.J.3    Kersten, M.J.4    Van Oers, M.5    Raymakers, R.6
  • 36
    • 27144441760 scopus 로고    scopus 로고
    • Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and-17p13 in myeloma patients treated with high-dose therapy
    • Gertz MA, Lacy MQ, Dispenzieri A, Greipp PR, Litzow MR, Henderson KJ et al. Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and-17p13 in myeloma patients treated with high-dose therapy. Blood 2005; 106: 2837-2840.
    • (2005) Blood , vol.106 , pp. 2837-2840
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3    Greipp, P.R.4    Litzow, M.R.5    Henderson, K.J.6
  • 37
    • 77950607507 scopus 로고    scopus 로고
    • Stem cell transplantation in multiple myeloma: Impact of response failure with thalidomide or lenalidomide induction
    • quiz 2560
    • Gertz MA, Kumar S, Lacy MQ, Dispenzieri A, Dingli D, Hayman SR et al. Stem cell transplantation in multiple myeloma: impact of response failure with thalidomide or lenalidomide induction. Blood 2010; 115: 2348-2353; quiz 2560.
    • (2010) Blood , vol.115 , pp. 2348-2353
    • Gertz, M.A.1    Kumar, S.2    Lacy, M.Q.3    Dispenzieri, A.4    Dingli, D.5    Hayman, S.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.