메뉴 건너뛰기




Volumn 22, Issue 2, 2013, Pages 117-125

Emerging role of epigenetics and miRNA in diabetic cardiomyopathy

Author keywords

Cardiomyopathy; Diabetes; Epigenetics

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; ELASTIN; EXPORTIN 5; FATTY ACID; GLUCOSE; HISTONE H2A; HISTONE H2B; HISTONE H3; HISTONE H4; MICRORNA; MICRORNA 1; MICRORNA 133; MICRORNA 29; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN KINASE C; PROTEIN KINASE PIM 1; PROTEIN MCL 1; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RIBONUCLEASE III; RNA POLYMERASE II; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SUPEROXIDE DISMUTASE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

EID: 84873410231     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2012.07.004     Document Type: Review
Times cited : (76)

References (92)
  • 1
    • 0016251063 scopus 로고
    • Role of diabetes in congestive heart failure: The Framingham study
    • W.B. Kannel, M. Hjortland, and W.P. Castelli Role of diabetes in congestive heart failure: the Framingham study Am J Cardiol 34 1974 29 34
    • (1974) Am J Cardiol , vol.34 , pp. 29-34
    • Kannel, W.B.1    Hjortland, M.2    Castelli, W.P.3
  • 3
    • 39749168495 scopus 로고    scopus 로고
    • Tackling heart failure in the twenty-first century
    • J.O. Mudd, and D.A. Kass Tackling heart failure in the twenty-first century Nature 451 2008 919 928
    • (2008) Nature , vol.451 , pp. 919-928
    • Mudd, J.O.1    Kass, D.A.2
  • 4
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Y. Lee, M. Kim, J. Han, K.H. Yeom, S. Lee, and S.H. Baek MicroRNA genes are transcribed by RNA polymerase II EMBO J 23 2004 4051 4060
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6
  • 5
    • 49149127971 scopus 로고    scopus 로고
    • Put your chips on transcriptomics
    • G.W. Dorn, and S.J. Matkovich Put your chips on transcriptomics Circulation 118 2008 216 218
    • (2008) Circulation , vol.118 , pp. 216-218
    • Dorn, G.W.1    Matkovich, S.J.2
  • 7
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • G. Egger, G. Liang, A. Aparicio, and P.A. Jones Epigenetics in human disease and prospects for epigenetic therapy Nature 429 2004 457 463
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 9
    • 0027751663 scopus 로고
    • The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • R.C. Lee, R.L. Feinbaum, and V. Ambros The C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843 854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 10
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • V. Ambros microRNAs: tiny regulators with great potential Cell 107 2001 823 826
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 12
    • 34247364093 scopus 로고    scopus 로고
    • Mechanisms of microRNA-mediated gene regulation in animal cells
    • T.W. Nilsen Mechanisms of microRNA-mediated gene regulation in animal cells Trends Genet 23 2007 243 249
    • (2007) Trends Genet , vol.23 , pp. 243-249
    • Nilsen, T.W.1
  • 13
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: How many mechanisms?
    • R.S. Pillai, S.N. Bhattacharyya, and W. Filipowicz Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 17 2007 118 126
    • (2007) Trends Cell Biol , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 15
    • 77955661276 scopus 로고    scopus 로고
    • MicroRNAs in cardiovascular diseases: Biology and potential clinical applications
    • R. Kartha, and S. Subramanian MicroRNAs in cardiovascular diseases: biology and potential clinical applications J Cardiovasc Transl Res 3 2009 256 270
    • (2009) J Cardiovasc Transl Res , vol.3 , pp. 256-270
    • Kartha, R.1    Subramanian, S.2
  • 17
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
    • H. King, R.E. Aubert, and W.H. Herman Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections Diabetes Care 21 1998 1414 1431
    • (1998) Diabetes Care , vol.21 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 19
    • 4143140134 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications
    • Z.Y. Fang, J.B. Prins, and T.H. Marwick Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications Endocr Rev 25 2004 543 567
    • (2004) Endocr Rev , vol.25 , pp. 543-567
    • Fang, Z.Y.1    Prins, J.B.2    Marwick, T.H.3
  • 20
    • 34249672811 scopus 로고    scopus 로고
    • Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: A shotgun lipidomics study
    • X. Han, J. Yang, K. Yang, Z. Zhao, D.R. Abendschein, and R.W. Gross Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: a shotgun lipidomics study Biochemistry 46 2007 6417 6428
    • (2007) Biochemistry , vol.46 , pp. 6417-6428
    • Han, X.1    Yang, J.2    Yang, K.3    Zhao, Z.4    Abendschein, D.R.5    Gross, R.W.6
  • 23
    • 75749104166 scopus 로고    scopus 로고
    • Left ventricular diastolic function in type 2 diabetes mellitus: Prevalence and association with myocardial and vascular disease
    • M.K. Poulsen, J.E. Henriksen, J. Dahl, A. Johansen, O. Gerke, and W. Vach Left ventricular diastolic function in type 2 diabetes mellitus: prevalence and association with myocardial and vascular disease Circ Cardiovasc Imaging 3 2010 24 31
    • (2010) Circ Cardiovasc Imaging , vol.3 , pp. 24-31
    • Poulsen, M.K.1    Henriksen, J.E.2    Dahl, J.3    Johansen, A.4    Gerke, O.5    Vach, W.6
  • 24
    • 0036271393 scopus 로고    scopus 로고
    • Cardiovascular function in patients with insulin-dependent diabetes mellitus: A study using noninvasive methods
    • S.K. Rajan, and S.M. Gokhale Cardiovascular function in patients with insulin-dependent diabetes mellitus: a study using noninvasive methods Ann N Y Acad Sci 958 2002 425 430
    • (2002) Ann N y Acad Sci , vol.958 , pp. 425-430
    • Rajan, S.K.1    Gokhale, S.M.2
  • 27
    • 0034930587 scopus 로고    scopus 로고
    • Left ventricular mass and systolic function in African diabetic patients: Association with microalbuminuria
    • J.C. Mbanya, E. Sobngwi, D.S. Mbanya, and K.B. Ngu Left ventricular mass and systolic function in African diabetic patients: association with microalbuminuria Diabetes Metab 27 2001 378 382
    • (2001) Diabetes Metab , vol.27 , pp. 378-382
    • Mbanya, J.C.1    Sobngwi, E.2    Mbanya, D.S.3    Ngu, K.B.4
  • 28
    • 0021237665 scopus 로고
    • Exercise-induced left ventricular dysfunction in young men with asymptomatic diabetes mellitus (diabetic cardiomyopathy)
    • A. Vered, A. Battler, P. Segal, D. Liberman, Y. Yerushalmi, and M. Berezin Exercise-induced left ventricular dysfunction in young men with asymptomatic diabetes mellitus (diabetic cardiomyopathy) Am J Cardiol 54 1984 633 637
    • (1984) Am J Cardiol , vol.54 , pp. 633-637
    • Vered, A.1    Battler, A.2    Segal, P.3    Liberman, D.4    Yerushalmi, Y.5    Berezin, M.6
  • 30
    • 42649097971 scopus 로고    scopus 로고
    • Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetes
    • N. Ozasa, Y. Furukawa, T. Morimoto, E. Tadamura, T. Kita, and T. Kimura Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetes Hypertens Res 31 2008 425 432
    • (2008) Hypertens Res , vol.31 , pp. 425-432
    • Ozasa, N.1    Furukawa, Y.2    Morimoto, T.3    Tadamura, E.4    Kita, T.5    Kimura, T.6
  • 31
    • 36749094626 scopus 로고    scopus 로고
    • Abnormal left ventricular longitudinal functional reserve in patients with diabetes mellitus: Implication for detecting subclinical myocardial dysfunction using exercise tissue Doppler echocardiography
    • J.W. Ha, H.C. Lee, E.S. Kang, C.M. Ahn, J.M. Kim, and J.A. Ahn Abnormal left ventricular longitudinal functional reserve in patients with diabetes mellitus: implication for detecting subclinical myocardial dysfunction using exercise tissue Doppler echocardiography Heart 93 2007 1571 1576
    • (2007) Heart , vol.93 , pp. 1571-1576
    • Ha, J.W.1    Lee, H.C.2    Kang, E.S.3    Ahn, C.M.4    Kim, J.M.5    Ahn, J.A.6
  • 32
    • 10344255610 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Mechanisms, diagnosis and treatment
    • S.A. Hayat, B. Patel, R.S. Khattar, and R.A. Malik Diabetic cardiomyopathy: mechanisms, diagnosis and treatment Clin Sci (Lond) 107 2004 539 557
    • (2004) Clin Sci (Lond) , vol.107 , pp. 539-557
    • Hayat, S.A.1    Patel, B.2    Khattar, R.S.3    Malik, R.A.4
  • 33
    • 0026321248 scopus 로고
    • Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (the Framingham Heart Study)
    • M. Galderisi, K.M. Anderson, P.W. Wilson, and D. Levy Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (the Framingham Heart Study) Am J Cardiol 68 1991 85 89
    • (1991) Am J Cardiol , vol.68 , pp. 85-89
    • Galderisi, M.1    Anderson, K.M.2    Wilson, P.W.3    Levy, D.4
  • 34
    • 84862578121 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Understanding the molecular and cellular basis to progress in diagnosis and treatment
    • I. Falcao-Pires, and A.F. Leite-Moreira Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment Heart Fail Rev 2011
    • (2011) Heart Fail Rev
    • Falcao-Pires, I.1    Leite-Moreira, A.F.2
  • 35
    • 14644425217 scopus 로고    scopus 로고
    • Mitochondrial energy metabolism in heart failure: A question of balance
    • J.M. Huss, and D.P. Kelly Mitochondrial energy metabolism in heart failure: a question of balance J Clin Invest 115 2005 547 555
    • (2005) J Clin Invest , vol.115 , pp. 547-555
    • Huss, J.M.1    Kelly, D.P.2
  • 37
    • 0037417725 scopus 로고    scopus 로고
    • A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
    • B.N. Finck, X. Han, M. Courtois, F. Aimond, J.M. Nerbonne, and A. Kovacs A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content Proc Natl Acad Sci USA 100 2003 1226 1231
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1226-1231
    • Finck, B.N.1    Han, X.2    Courtois, M.3    Aimond, F.4    Nerbonne, J.M.5    Kovacs, A.6
  • 38
    • 34347352169 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy revisited
    • S. Boudina, and E.D. Abel Diabetic cardiomyopathy revisited. Circulation 115 2007 3213 3223
    • (2007) Circulation , vol.115 , pp. 3213-3223
    • Boudina, S.1    Abel, E.D.2
  • 39
    • 0037117651 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms
    • M.E. Young, P. McNulty, and H. Taegtmeyer Adaptation and maladaptation of the heart in diabetes: part II: potential mechanisms Circulation 105 2002 1861 1870
    • (2002) Circulation , vol.105 , pp. 1861-1870
    • Young, M.E.1    McNulty, P.2    Taegtmeyer, H.3
  • 40
    • 33644629034 scopus 로고    scopus 로고
    • Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62
    • A. Rodriguez, A. Duran, M. Selloum, M.F. Champy, F.J. Diez-Guerra, and J.M. Flores Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62 Cell Metab 3 2006 211 222
    • (2006) Cell Metab , vol.3 , pp. 211-222
    • Rodriguez, A.1    Duran, A.2    Selloum, M.3    Champy, M.F.4    Diez-Guerra, F.J.5    Flores, J.M.6
  • 41
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group N Engl J Med 329 1993 977 986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 42
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group Lancet 352 1998 837 853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 43
    • 1642523851 scopus 로고    scopus 로고
    • Collagen cross-link breakers: A beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension
    • D. Susic, J. Varagic, J. Ahn, and E.D. Frohlich Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension Curr Drug Targets Cardiovasc Haematol Disord 4 2004 97 101
    • (2004) Curr Drug Targets Cardiovasc Haematol Disord , vol.4 , pp. 97-101
    • Susic, D.1    Varagic, J.2    Ahn, J.3    Frohlich, E.D.4
  • 44
    • 0029946123 scopus 로고    scopus 로고
    • Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats
    • G.R. Norton, G. Candy, and A.J. Woodiwiss Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats Circulation 93 1996 1905 1912
    • (1996) Circulation , vol.93 , pp. 1905-1912
    • Norton, G.R.1    Candy, G.2    Woodiwiss, A.J.3
  • 45
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • A. Goldin, J.A. Beckman, A.M. Schmidt, and M.A. Creager Advanced glycation end products: sparking the development of diabetic vascular injury Circulation 114 2006 597 605
    • (2006) Circulation , vol.114 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 46
    • 0036773352 scopus 로고    scopus 로고
    • Advanced glycation endproduct-induced calcium handling impairment in mouse cardiac myocytes
    • R. Petrova, Y. Yamamoto, K. Muraki, H. Yonekura, S. Sakurai, and T. Watanabe Advanced glycation endproduct-induced calcium handling impairment in mouse cardiac myocytes J Mol Cell Cardiol 34 2002 1425 1431
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1425-1431
    • Petrova, R.1    Yamamoto, Y.2    Muraki, K.3    Yonekura, H.4    Sakurai, S.5    Watanabe, T.6
  • 47
    • 0344548127 scopus 로고    scopus 로고
    • Selective effects of oxygen free radicals on excitation-contraction coupling in ventricular muscle. Implications for the mechanism of stunned myocardium
    • W.D. Gao, Y. Liu, and E. Marban Selective effects of oxygen free radicals on excitation-contraction coupling in ventricular muscle. Implications for the mechanism of stunned myocardium Circulation 94 1996 2597 2604
    • (1996) Circulation , vol.94 , pp. 2597-2604
    • Gao, W.D.1    Liu, Y.2    Marban, E.3
  • 48
    • 77953440109 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy, causes and effects
    • S. Boudina, and E.D. Abel Diabetic cardiomyopathy, causes and effects Rev Endocr Metab Disord 11 2010 31 39
    • (2010) Rev Endocr Metab Disord , vol.11 , pp. 31-39
    • Boudina, S.1    Abel, E.D.2
  • 49
    • 33749513188 scopus 로고    scopus 로고
    • Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy
    • L. Cai, Y. Wang, G. Zhou, T. Chen, Y. Song, and X. Li Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy J Am Coll Cardiol 48 2006 1688 1697
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1688-1697
    • Cai, L.1    Wang, Y.2    Zhou, G.3    Chen, T.4    Song, Y.5    Li, X.6
  • 50
    • 33644766038 scopus 로고    scopus 로고
    • Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
    • X. Shen, S. Zheng, N.S. Metreveli, and P.N. Epstein Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy Diabetes 55 2006 798 805
    • (2006) Diabetes , vol.55 , pp. 798-805
    • Shen, X.1    Zheng, S.2    Metreveli, N.S.3    Epstein, P.N.4
  • 51
    • 67651156448 scopus 로고    scopus 로고
    • Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets
    • V. Jaquet, L. Scapozza, R.A. Clark, K.H. Krause, and J.D. Lambeth Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets Antioxid Redox Signal 11 2009 2535 2552
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2535-2552
    • Jaquet, V.1    Scapozza, L.2    Clark, R.A.3    Krause, K.H.4    Lambeth, J.D.5
  • 52
    • 0027981889 scopus 로고
    • Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia
    • P. Xia, T. Inoguchi, T.S. Kern, R.L. Engerman, P.J. Oates, and G.L. King Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia Diabetes 43 1994 1122 1129
    • (1994) Diabetes , vol.43 , pp. 1122-1129
    • Xia, P.1    Inoguchi, T.2    Kern, T.S.3    Engerman, R.L.4    Oates, P.J.5    King, G.L.6
  • 53
    • 1642388834 scopus 로고    scopus 로고
    • PKC-alpha regulates cardiac contractility and propensity toward heart failure
    • J.C. Braz, K. Gregory, A. Pathak, W. Zhao, B. Sahin, and R. Klevitsky PKC-alpha regulates cardiac contractility and propensity toward heart failure Nat Med 10 2004 248 254
    • (2004) Nat Med , vol.10 , pp. 248-254
    • Braz, J.C.1    Gregory, K.2    Pathak, A.3    Zhao, W.4    Sahin, B.5    Klevitsky, R.6
  • 54
    • 0030589152 scopus 로고    scopus 로고
    • Initiation of acute phase response and synthesis of cytokines
    • A. Koj Initiation of acute phase response and synthesis of cytokines Biochim Biophys Acta 1317 1996 84 94
    • (1996) Biochim Biophys Acta , vol.1317 , pp. 84-94
    • Koj, A.1
  • 55
    • 0028110232 scopus 로고
    • Preservation of left ventricular function and coronary flow by angiotensin I-converting enzyme inhibition in the hypertensive-diabetic Dahl rat
    • M.B. Given, R.F. Lowe, C.R. Gelvin, G.E. Sander, and T.D. Giles Preservation of left ventricular function and coronary flow by angiotensin I-converting enzyme inhibition in the hypertensive-diabetic Dahl rat Am J Hypertens 7 1994 919 925
    • (1994) Am J Hypertens , vol.7 , pp. 919-925
    • Given, M.B.1    Lowe, R.F.2    Gelvin, C.R.3    Sander, G.E.4    Giles, T.D.5
  • 56
    • 10044268430 scopus 로고    scopus 로고
    • Altered cardiac calcium handling in diabetes
    • D.D. Belke, and W.H. Dillmann Altered cardiac calcium handling in diabetes Curr Hypertens Rep 6 2004 424 429
    • (2004) Curr Hypertens Rep , vol.6 , pp. 424-429
    • Belke, D.D.1    Dillmann, W.H.2
  • 57
    • 0030610027 scopus 로고    scopus 로고
    • Regulation of intracellular Ca2+ in the heart during diabetes
    • G.N. Pierce, and J.C. Russell Regulation of intracellular Ca2+ in the heart during diabetes Cardiovasc Res 34 1997 41 47
    • (1997) Cardiovasc Res , vol.34 , pp. 41-47
    • Pierce, G.N.1    Russell, J.C.2
  • 58
    • 20344392202 scopus 로고    scopus 로고
    • Epigenetics - An epicenter of gene regulation: Histones and histone-modifying enzymes
    • M. Biel, V. Wascholowski, and A. Giannis Epigenetics - an epicenter of gene regulation: histones and histone-modifying enzymes Angew Chem Int Ed Engl 44 2005 3186 3216
    • (2005) Angew Chem Int Ed Engl , vol.44 , pp. 3186-3216
    • Biel, M.1    Wascholowski, V.2    Giannis, A.3
  • 59
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • A. El-Osta, D. Brasacchio, D. Yao, A. Pocai, P.L. Jones, and R.G. Roeder Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia J Exp Med 205 2008 2409 2417
    • (2008) J Exp Med , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6
  • 60
    • 65549170303 scopus 로고    scopus 로고
    • Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
    • D. Brasacchio, J. Okabe, C. Tikellis, A. Balcerczyk, P. George, and E.K. Baker Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail Diabetes 58 2009 1229 1236
    • (2009) Diabetes , vol.58 , pp. 1229-1236
    • Brasacchio, D.1    Okabe, J.2    Tikellis, C.3    Balcerczyk, A.4    George, P.5    Baker, E.K.6
  • 61
    • 58149345088 scopus 로고    scopus 로고
    • Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: An epigenetic study in diabetes
    • F. Miao, D.D. Smith, L. Zhang, A. Min, W. Feng, and R. Natarajan Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes Diabetes 57 2008 3189 3198
    • (2008) Diabetes , vol.57 , pp. 3189-3198
    • Miao, F.1    Smith, D.D.2    Zhang, L.3    Min, A.4    Feng, W.5    Natarajan, R.6
  • 62
    • 77749264372 scopus 로고    scopus 로고
    • Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes
    • A.B. Gaikwad, S.G. Sayyed, J. Lichtnekert, K. Tikoo, and H.J. Anders Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes Am J Pathol 176 2010 1079 1083
    • (2010) Am J Pathol , vol.176 , pp. 1079-1083
    • Gaikwad, A.B.1    Sayyed, S.G.2    Lichtnekert, J.3    Tikoo, K.4    Anders, H.J.5
  • 63
    • 4544358659 scopus 로고    scopus 로고
    • Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
    • S. Chang, T.A. McKinsey, C.L. Zhang, J.A. Richardson, J.A. Hill, and E.N. Olson Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development Mol Cell Biol 24 2004 8467 8476
    • (2004) Mol Cell Biol , vol.24 , pp. 8467-8476
    • Chang, S.1    McKinsey, T.A.2    Zhang, C.L.3    Richardson, J.A.4    Hill, J.A.5    Olson, E.N.6
  • 64
    • 0142186685 scopus 로고    scopus 로고
    • HATs off to Hop: Recruitment of a class i histone deacetylase incriminates a novel transcriptional pathway that opposes cardiac hypertrophy
    • Y. Hamamori, and M.D. Schneider HATs off to Hop: recruitment of a class I histone deacetylase incriminates a novel transcriptional pathway that opposes cardiac hypertrophy J Clin Invest 112 2003 824 826
    • (2003) J Clin Invest , vol.112 , pp. 824-826
    • Hamamori, Y.1    Schneider, M.D.2
  • 65
    • 67449127083 scopus 로고    scopus 로고
    • Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: Mechanisms and potential clinical implications
    • D.S. Schrump Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications Clin Cancer Res 15 2009 3947 3957
    • (2009) Clin Cancer Res , vol.15 , pp. 3947-3957
    • Schrump, D.S.1
  • 66
    • 85028516803 scopus 로고    scopus 로고
    • High glucose leads to increased inflammatory gene expression via epigenetic histone H3 lysine 9 methylation in cardiomyocyte
    • X.Y. Yu, Y.J. Geng, Q.X. Lin, H.S. Xia, Z.X. Shan, and M. Yang High glucose leads to increased inflammatory gene expression via epigenetic histone H3 lysine 9 methylation in cardiomyocyte Circulation 2010 122
    • (2010) Circulation , pp. 122
    • Yu, X.Y.1    Geng, Y.J.2    Lin, Q.X.3    Xia, H.S.4    Shan, Z.X.5    Yang, M.6
  • 67
    • 77649197044 scopus 로고    scopus 로고
    • Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure
    • M. Movassagh, M.K. Choy, M. Goddard, M.R. Bennett, T.A. Down, and R.S. Foo Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure PLoS One 5 2010 e8564
    • (2010) PLoS One , vol.5 , pp. 8564
    • Movassagh, M.1    Choy, M.K.2    Goddard, M.3    Bennett, M.R.4    Down, T.A.5    Foo, R.S.6
  • 68
    • 74049128799 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes
    • Y.H. Kao, Y.C. Chen, C.C. Cheng, T.I. Lee, Y.J. Chen, and S.A. Chen Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes Crit Care Med 38 2010 217 222
    • (2010) Crit Care Med , vol.38 , pp. 217-222
    • Kao, Y.H.1    Chen, Y.C.2    Cheng, C.C.3    Lee, T.I.4    Chen, Y.J.5    Chen, S.A.6
  • 70
    • 0031801448 scopus 로고    scopus 로고
    • The cyclin kinase inhibitor p21WAF1, CIP1 is increased in experimental diabetic nephropathy: Potential role in glomerular hypertrophy
    • C.J. Kuan, M. al-Douahji, and S.J. Shankland The cyclin kinase inhibitor p21WAF1, CIP1 is increased in experimental diabetic nephropathy: potential role in glomerular hypertrophy J Am Soc Nephrol 9 1998 986 993
    • (1998) J Am Soc Nephrol , vol.9 , pp. 986-993
    • Kuan, C.J.1    Al-Douahji, M.2    Shankland, S.J.3
  • 71
    • 0032840013 scopus 로고    scopus 로고
    • Oxidative stress induces p21 expression in pancreatic islet cells: Possible implication in beta-cell dysfunction
    • H. Kaneto, Y. Kajimoto, Y. Fujitani, T. Matsuoka, K. Sakamoto, and M. Matsuhisa Oxidative stress induces p21 expression in pancreatic islet cells: possible implication in beta-cell dysfunction Diabetologia 42 1999 1093 1097
    • (1999) Diabetologia , vol.42 , pp. 1093-1097
    • Kaneto, H.1    Kajimoto, Y.2    Fujitani, Y.3    Matsuoka, T.4    Sakamoto, K.5    Matsuhisa, M.6
  • 72
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • R.W. Carthew, and E.J. Sontheimer Origins and mechanisms of miRNAs and siRNAs Cell 136 2009 642 655
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 74
    • 33846945735 scopus 로고    scopus 로고
    • Processing of intronic microRNAs
    • Y.K. Kim, and V.N. Kim Processing of intronic microRNAs EMBO J 26 2007 775 783
    • (2007) EMBO J , vol.26 , pp. 775-783
    • Kim, Y.K.1    Kim, V.N.2
  • 76
    • 70849093653 scopus 로고    scopus 로고
    • A high-resolution structure of the pre-microRNA nuclear export machinery
    • C. Okada, E. Yamashita, S.J. Lee, S. Shibata, J. Katahira, and A. Nakagawa A high-resolution structure of the pre-microRNA nuclear export machinery Science 326 2009 1275 1279
    • (2009) Science , vol.326 , pp. 1275-1279
    • Okada, C.1    Yamashita, E.2    Lee, S.J.3    Shibata, S.4    Katahira, J.5    Nakagawa, A.6
  • 78
    • 55249123349 scopus 로고    scopus 로고
    • Cardiac dissonance without conductors: How dicer depletion provokes chaos in the heart
    • T. Thum Cardiac dissonance without conductors: how dicer depletion provokes chaos in the heart Circulation 118 2008 1524 1527
    • (2008) Circulation , vol.118 , pp. 1524-1527
    • Thum, T.1
  • 79
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • V.N. Kim MicroRNA biogenesis: coordinated cropping and dicing Nat Rev Mol Cell Biol 6 2005 376 385
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 80
    • 34447318648 scopus 로고    scopus 로고
    • MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy?
    • Y. Cheng, R. Ji, J. Yue, J. Yang, X. Liu, and H. Chen MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol 170 2007 1831 1840
    • (2007) Am J Pathol , vol.170 , pp. 1831-1840
    • Cheng, Y.1    Ji, R.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6
  • 81
    • 25844443758 scopus 로고    scopus 로고
    • Not miR-ly muscular: MicroRNAs and muscle development
    • J. Brennecke, A. Stark, and S.M. Cohen Not miR-ly muscular: microRNAs and muscle development Genes Dev 19 2005 2261 2264
    • (2005) Genes Dev , vol.19 , pp. 2261-2264
    • Brennecke, J.1    Stark, A.2    Cohen, S.M.3
  • 82
    • 79957497037 scopus 로고    scopus 로고
    • Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling
    • Katare R, Caporali A, Zentilin L, Avolio E, Sala-Newby G, Oikawa A, et al. Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling. Circ Res;108:1238-1251.
    • Circ Res , vol.108 , pp. 1238-1251
    • Katare, R.1    Caporali, A.2    Zentilin, L.3    Avolio, E.4    Sala-Newby, G.5    Oikawa, A.6
  • 83
    • 34250378330 scopus 로고    scopus 로고
    • MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts
    • J. Xiao, X. Luo, H. Lin, Y. Zhang, Y. Lu, and N. Wang MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts J Biol Chem 282 2007 12363 12367
    • (2007) J Biol Chem , vol.282 , pp. 12363-12367
    • Xiao, J.1    Luo, X.2    Lin, H.3    Zhang, Y.4    Lu, Y.5    Wang, N.6
  • 84
    • 59849128881 scopus 로고    scopus 로고
    • MiR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling
    • 176p following 178
    • Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, et al. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res 2009;104:170-178, 176p following 178.
    • (2009) Circ Res , vol.104 , pp. 170-178
    • Duisters, R.F.1    Tijsen, A.J.2    Schroen, B.3    Leenders, J.J.4    Lentink, V.5    Van Der Made, I.6
  • 85
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • M. Fabbri, R. Garzon, A. Cimmino, Z. Liu, N. Zanesi, and E. Callegari MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B Proc Natl Acad Sci USA 104 2007 15805 15810
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15805-15810
    • Fabbri, M.1    Garzon, R.2    Cimmino, A.3    Liu, Z.4    Zanesi, N.5    Callegari, E.6
  • 86
    • 34548687035 scopus 로고    scopus 로고
    • Mir-29 regulates Mcl-1 protein expression and apoptosis
    • J.L. Mott, S. Kobayashi, S.F. Bronk, and G.J. Gores mir-29 regulates Mcl-1 protein expression and apoptosis Oncogene 26 2007 6133 6140
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 87
    • 24944496184 scopus 로고    scopus 로고
    • Role of histone and transcription factor acetylation in diabetes pathogenesis
    • S.G. Gray, and P. De Meyts Role of histone and transcription factor acetylation in diabetes pathogenesis Diabetes Metab Res Rev 21 2005 416 433
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 416-433
    • Gray, S.G.1    De Meyts, P.2
  • 88
    • 31744432337 scopus 로고    scopus 로고
    • The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
    • J.F. Chen, E.M. Mandel, J.M. Thomson, Q. Wu, T.E. Callis, and S.M. Hammond The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation Nat Genet 38 2006 228 233
    • (2006) Nat Genet , vol.38 , pp. 228-233
    • Chen, J.F.1    Mandel, E.M.2    Thomson, J.M.3    Wu, Q.4    Callis, T.E.5    Hammond, S.M.6
  • 89
    • 7044285911 scopus 로고    scopus 로고
    • Probing microRNAs with microarrays: Tissue specificity and functional inference
    • T. Babak, W. Zhang, Q. Morris, B.J. Blencowe, and T.R. Hughes Probing microRNAs with microarrays: tissue specificity and functional inference RNA 10 2004 1813 1819
    • (2004) RNA , vol.10 , pp. 1813-1819
    • Babak, T.1    Zhang, W.2    Morris, Q.3    Blencowe, B.J.4    Hughes, T.R.5
  • 91
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Y. Zhao, E. Samal, and D. Srivastava Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis Nature 436 2005 214 220
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 92
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Y. Saito, G. Liang, G. Egger, J.M. Friedman, J.C. Chuang, and G.A. Coetzee Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells Cancer Cell 9 2006 435 443
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.