Cytotoxicity, oxidative stress and expression of adhesion molecules in human umbilical vein endothelial cells exposed to dust from paints with or without nanoparticles

Nanotoxicology

Volumn 7, Issue 2, 2013, Pages 117-134

  Mikkelsen, Lone ^a   Jensen, Keld A ^b   Koponen, Ismo K ^b   Saber, Anne T ^b   Wallin, Håkan ^a,b   Loft, Steffen ^a   Vogel, Ulla ^b   Møller, Peter ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

Author keywords

Atherosclerosis; Cardiovascular disease; DCF; HUVEC; Nanoparticles

Indexed keywords

ALUMINUM SILICATE; AXILATE; CARBON; CARBON BLACK; CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; NANOMATERIAL; NANOPARTICLE; NANOSILICASOL; PAINT; REACTIVE OXYGEN METABOLITE; SILICON DERIVATIVE; TITANIUM DIOXIDE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL SURFACE; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOTOXICITY; DUST; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; OXIDATIVE STRESS; PARTICLE SIZE; PHOTOCATALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SAND; UMBILICAL VEIN ENDOTHELIAL CELL;

ALUMINUM SILICATES; CELL ADHESION MOLECULES; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DUST; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; METAL NANOPARTICLES; OXIDATIVE STRESS; PAINT; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SOOT; TITANIUM; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84873350649     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.641604     Document Type: Article

References (34)

1. Brown DM, Dickson C, Duncan P, Al-Attili F, Stone V. 2010. Interaction between nanoparticles and cytokine proteins: Impact on protein and particle functionality. Nanotechnology 21:215104
2. Carlos TM, Schwartz BR, Kovach NL, Yee E, Rosa M, Osborn L, et al. 1990. Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-Activated cultured human endothelial cells. Blood 76:965-970
3. Elder A, Yang H, Gwiazda R, Teng X, Thurston S He H, Oberdörster G. 2007. Testing nanomaterials of unknown toxicity: An example based on platinum nanoparticles of different shapes. Adv Mater 19: 3124-3129
4. Ema M, Kobayashi N, Naya M, Hanai S, Nakanishi J. 2010. Reproductive and developmental toxicity studies of manufactured nanomaterials. Reprod Toxicol 30:343-352
5. Frikke-Schmidt H, Roursgaard M, Lykkesfeldt J, Loft S, Nøjgaard JK, Møller P 2011.Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells. Tox Lett 203:181-189
6. Gohler D, Stintz M, Hillemann L, Vorbau M. 2010. Characterization of nanoparticle release from surface coatings by the simulation of a sanding process. Ann Occup Hyg 54:615-624
7. Herzog E, Byrne HJ, Davoren M, Casey A, Duschl A, Oostingh GJ. 2009. Dispersion medium modulates oxidative stress response of human lung epithelial cells upon exposure to carbon nanomaterial samples. Toxicol Appl Pharmacol 236:276-281
8. Jacobsen NR, Møller P, Cohn CA, Loft S, Vogel U, Wallin H 2008a. Diesel exhaust particles are mutagenic in FE1-MutaMouse lung epithelial cells. Mutat Res 641:54-57
9. Jacobsen NR, Pojana G, White P, Møller P, Cohn CA, Korsholm KS, et al. 2008b. Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells. Environ Mol Mutagen 49:476-487
10. Koponen IK, Jensen KA, Schneider T 2010. Comparison of dust released from sanding conventional and nanoparticle-Doped wall and wood coatings. J Expo Sci Environ Epidemiol 21:450-463
11. LeBel CP, Ischiropoulos H, Bondy SC. 1992. Evaluation of the probe 2¢,7¢-Dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5:227-231
12. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, et al. 2003 Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect 111: 455-460
13. Li N, Xia T, Nel AE. 2008. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic Biol Med 44:1689-1699
14. Libby P. 2002. Inflammation in atherosclerosis. Nature 420:868-874
15. Li R, Ning Z, Majumdar R, Cui J, Takabe W, Jen N, et al. 2010. Ultrafine particles from diesel vehicle emissions at different driving cycles induce differential vascular pro-inflammatory responses: Implication of chemical components and NF-kappaB signaling. Part Fibre Toxicol 7:6
16. Lopez-Fonseca R, Landa I, Elizundia U, Gutierrez-Ortiz MA, Gonzalez-Velasco Jr. 2006. Thermokinetic modeling of the combustion of carbonaceous particulate matter. Combustion and Flame 144:398-406
17. Lynch I, Salvati A, Dawson KA 2009. What the cell see? Nature Nanotechnol 4: 546-547
18. Møller P, Jacobsen NR, Folkmann JK, Danielsen PH, Mikkelsen L, Hemmingsen JG, et al. 2010. Role of oxidative damage in toxicity of particulates. Free Radic Res 44:1-46
19. Møller P, Loft S. 2010. Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution. Environ Health Perspect 118:1126-1136
20. Møller P, Mikkelsen L, Vesterdal LK, Folkmann JK, Forchhammer L, Roursgaard M, et al. 2011. Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis. Crit Rev Toxicol 41:339-368
21. Montiel-Davalos A, Alfaro-Moreno E, Lopez-Marure R 2007. PM2.5 and PM10 induce the expression of adhesion molecules and the adhesion of monocytic cells to human umbilical vein endothelial cells. Inhal Toxicol 19(SUPPL1): 91-98
22. Napierska D, Thomassen LC, Rabolli V, Lison D, Gonzalez L, Kirsch-Volders M, et al. 2009. Size-Dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small 5:846-853
23. Nurkiewicz TR, Porter DW, Hubbs AF, Stone S, Chen BT, Frazer DG, et al. 2009. Pulmonary nanoparticle exposure disrupts systemic microvascular nitric oxide signaling. Toxicol Sci 110:191-203
24. Nyhlen K, Linden M, Andersson R, Uppugunduri S. 2000. Corticosteroids and interferons inhibit cytokine-induced production of IL-8 by human endothelial cells. Cytokine 12:355-360
25. Oberdörster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, et al. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: Elements of a screening strategy. Part Fibre Toxicol 2:8
26. Saber AT, Jensen KA, Jacobsen NR, Birkedal R, Mikkelsen L, Møller P, et al. 2011a. Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers. Nanotoxicology (DOI: 10.3109/17435390. 2011.587900
27. Saber AT, Koponen IK, Jensen KA, Jacobsen NR, Mikkelsen L, Møller P, et al. 2011b. Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers. Nanotoxicology doi: 10.3109/17435390.2011.620745
28. Schlorf T, Meincke M, Kossel E, Glüer C, Jansen O, Mentlein R. 2011. Biological properties of iron oxide nanoparticles for cellular and molecular magnetic resonance imaging. Int J Mol Sci 12:12-23
29. Seaton A, Soutar A, Crawford V, Elton R, McNerlan S,Cherrie J, Watt M, Agius R, Stout R. 1999. Particulate air pollution and the blood. Thorax 54:1027-1032
30. Silva VM, Corson N, Elder A, Oberdörster G. 2005. The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP). Toxicol Sci 8:983-989
31. Van Tiel ST, Wielopolski PA, Houston GC, Krestin GP, Bernsen MR. 2010. Variations in labeling protocol influence incorporation, distribution and retention of iral oxide nanoparticles into human umbilical vein endothelial cells. Contrast Media Mol Imaging 5:247-257
32. VesterdalLK, Folkmann JK, JacobsenNR, Sheykhzade M,Wallin H, Loft S, Møller,P.2009.Modest vasomotordysfunctioninducedbylowdosesof C60 fullerenes inapolipoproteinE knockoutmicewith different degree of atherosclerosis. Part Fibre Toxicol 6:5
33. Vesterdal LK, Folkmann JK, Jacobsen NR, Sheykhzade M, Wallin H, Loft S, Møller P. 2010. Pulmonary exposure to carbon black nanoparticles and vascular effects. Part Fibre Toxicol 7:33
34. Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V. 2002. Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 184:172-179