Simultaneous determination and pharmacokinetic study of polyphyllin I, polyphyllin II, polyphyllin VI and polyphyllin VII in beagle dog plasma after oral administration of Rhizoma Paridis extracts by LC-MS-MS

Biomedical Chromatography

Volumn 27, Issue 3, 2013, Pages 343-348

  Yin, Xingbin ^a   Qu, Changhai ^a   Li, Zhaoxia ^b   Zhai, Yujing ^c   Cao, Sali ^a   Lin, Longfei ^a   Feng, Lijun ^a   Yan, Lei ^a   Ni, Jian ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c Beijing Jianhua Experimental School China   (China)

Author keywords

Beagle dog plasma; LC MS MS; Pharmacokinetics; Polyphyllin; Saponin

Indexed keywords

ELECTROSPRAY IONIZATION;

BEAGLE DOG; BEAGLE DOG PLASMA; DOG PLASMA; LC-MS-MS; LC.MS/MS; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; POLYPHYLLIN; SAPONIN; SIMULTANEOUS DETERMINATIONS;

PHARMACOKINETICS;

ACETONITRILE; PLANT EXTRACT; POLYPHYLLIN I; POLYPHYLLIN II; POLYPHYLLIN VI; POLYPHYLLIN VII; RHIZOMA PARIDIS EXTRACT; UNCLASSIFIED DRUG; WATER;

ARTICLE; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; REVERSED PHASE LIQUID CHROMATOGRAPHY;

EID: 84873258504     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2797     Document Type: Article

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