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Volumn 124, Issue 5, 2012, Pages 101-109

The implications of tamper-resistant formulations for opioid rotation

Author keywords

Chronic pain; Opioids; Pain management; Substance abuse; Tamper resistance

Indexed keywords

MORPHINE; MORPHINE PLUS NALTREXONE; MORPHINE SULFATE; MORPHINE SULFATE PLUS NALTREXONE; NALTREXONE; OPIATE; OXYCODONE; OXYMORPHONE; UNCLASSIFIED DRUG; MORPHINE, NALTREXONE COMBINATION; NARCOTIC ANALGESIC AGENT;

EID: 84873254674     PISSN: 00325481     EISSN: 19419260     Source Type: Journal    
DOI: 10.3810/pgm.2012.09.2588     Document Type: Article
Times cited : (8)

References (64)
  • 1
    • 84876548272 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, National Center for Health Statistics, press release, Released November 15, 2006. Accessed July 19, 2012
    • Centers for Disease Control and Prevention, National Center for Health Statistics. New report finds pain affects millions of Americans [press release]. http://www.cdc.gov/media/pressrel/r061115.htm?s_cid=mediarel_r061115. Released November 15, 2006. Accessed July 19, 2012.
    • New Report Finds Pain Affects Millions of Americans
  • 2
    • 58949087497 scopus 로고    scopus 로고
    • American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain
    • Chou R, Fanciullo GJ, Fine PG, et al; American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain. 2009;10(2):113-130.
    • (2009) J Pain , vol.10 , Issue.2 , pp. 113-130
    • Chou, R.1    Fanciullo, G.J.2    Fine, P.G.3
  • 3
    • 38949130488 scopus 로고    scopus 로고
    • OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
    • Zhang W, Moskowitz RW, Nuki G, et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage. 2008;16(2):137-162.
    • (2008) Osteoarthritis Cartilage , vol.16 , Issue.2 , pp. 137-162
    • Zhang, W.1    Moskowitz, R.W.2    Nuki, G.3
  • 4
    • 34848925500 scopus 로고    scopus 로고
    • Clinical Efficacy Assessment Subcommittee of the American College of Physicians; American College of Physicians; American Pain Society Low Back Pain Guidelines Panel. Diagnosis and treatment of low back pain: A joint clinical practice guideline from the American College of Physicians and the American Pain Society
    • Chou R, Qaseem A, Snow V, et al; Clinical Efficacy Assessment Subcommittee of the American College of Physicians; American College of Physicians; American Pain Society Low Back Pain Guidelines Panel. Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society. Ann Intern Med. 2007;147(7):478-491.
    • (2007) Ann Intern Med , vol.147 , Issue.7 , pp. 478-491
    • Chou, R.1    Qaseem, A.2    Snow, V.3
  • 5
    • 68249114476 scopus 로고    scopus 로고
    • Pharmacological management of persistent pain in older persons
    • American Geriatrics Society Panel on Pharmacological Management of Persistent Pain in Older Persons
    • American Geriatrics Society Panel on Pharmacological Management of Persistent Pain in Older Persons. Pharmacological management of persistent pain in older persons. J Am Geriatr Soc. 2009;57(8): 1331-1346.
    • (2009) J Am Geriatr Soc , vol.57 , Issue.8 , pp. 1331-1346
  • 6
    • 33744816918 scopus 로고    scopus 로고
    • National Center for Health Statistics. Health, United States, Hyattsville, MD: US Dept of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 2007
    • National Center for Health Statistics. Health, United States, 2007. With Chartbook on Trends in the Health of Americans. Hyattsville, MD: US Dept of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 2007.
    • (2007) With Chartbook On Trends In the Health of Americans
  • 8
    • 0036812566 scopus 로고    scopus 로고
    • Opioid rotation in the treatment of joint pain. A review of 67 cases
    • Grilo RM, Bertin P, Scotto di Fazano C, et al. Opioid rotation in the treatment of joint pain. A review of 67 cases. Joint Bone Spine. 2002; 69(5):491-494.
    • (2002) Joint Bone Spine , vol.69 , Issue.5 , pp. 491-494
    • Grilo, R.M.1    Bertin, P.2    Scotto di Fazano, C.3
  • 9
    • 33746925643 scopus 로고    scopus 로고
    • Opioid switching: A systematic and critical review
    • Mercadante S, Bruera E. Opioid switching: a systematic and critical review. Cancer Treat Rev. 2006;32(4):304-315.
    • (2006) Cancer Treat Rev , vol.32 , Issue.4 , pp. 304-315
    • Mercadante, S.1    Bruera, E.2
  • 10
    • 0342313732 scopus 로고    scopus 로고
    • Opioid substitution to improve the effectiveness of chronic noncancer pain control: A chart review
    • Quang-Cantagrel ND, Wallace MS, Magnuson SK. Opioid substitution to improve the effectiveness of chronic noncancer pain control: a chart review. Anesth Analg. 2000;90(4):933-937.
    • (2000) Anesth Analg , vol.90 , Issue.4 , pp. 933-937
    • Quang-Cantagrel, N.D.1    Wallace, M.S.2    Magnuson, S.K.3
  • 11
    • 69849084738 scopus 로고    scopus 로고
    • Opioid switching and rotation in primary care: Implementation and clinical utility
    • Slatkin NE. Opioid switching and rotation in primary care: implementation and clinical utility. Curr Med Res Opin. 2009;25(9):2133-2150.
    • (2009) Curr Med Res Opin , vol.25 , Issue.9 , pp. 2133-2150
    • Slatkin, N.E.1
  • 12
    • 0032862399 scopus 로고    scopus 로고
    • Opioid rotation in chronic non-malignant pain patients. A retrospective study
    • Thomsen AB, Becker N, Eriksen J. Opioid rotation in chronic non-malignant pain patients. A retrospective study. Acta Anaesthesiol Scand. 1999;43(9):918-923.
    • (1999) Acta Anaesthesiol Scand , vol.43 , Issue.9 , pp. 918-923
    • Thomsen, A.B.1    Becker, N.2    Eriksen, J.3
  • 13
    • 33748918495 scopus 로고    scopus 로고
    • Opioids used in primary care for the management of pain: A pharmacologic, pharmacotherapeutic, and pharmacodynamic overview
    • In: Boswell MV, Cole BE, eds., 7th ed. New York, NY: Taylor and Francis
    • Barkin RL, Iasco AM, Barkin SJ. Opioids used in primary care for the management of pain: a pharmacologic, pharmacotherapeutic, and pharmacodynamic overview. In: Boswell MV, Cole BE, eds. Weiner's Pain Management: A Practical Guide for Clinicians. 7th ed. New York, NY: Taylor and Francis; 2005:789-804.
    • (2005) Weiner's Pain Management: A Practical Guide For Clinicians , pp. 789-804
    • Barkin, R.L.1    Iasco, A.M.2    Barkin, S.J.3
  • 14
    • 33744749555 scopus 로고    scopus 로고
    • Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers
    • Lötsch J, Geisslinger G. Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers. Pharmacog-enomics J. 2006;6(3):200-210.
    • (2006) Pharmacog-enomics J , vol.6 , Issue.3 , pp. 200-210
    • Lötsch, J.1    Geisslinger, G.2
  • 15
    • 18844451788 scopus 로고    scopus 로고
    • Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm
    • Pan L, Xu J, Yu R, Xu MM, Pan YX, Pasternak GW Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm. Neuroscience. 2005;133(1):209-220.
    • (2005) Neuroscience , vol.133 , Issue.1 , pp. 209-220
    • Pan, L.1    Xu, J.2    Yu, R.3    Xu, M.M.4    Pan, Y.X.5    Pasternak, G.W.6
  • 16
    • 0035923593 scopus 로고    scopus 로고
    • Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene
    • Pan YX, Xu J, Mahurter L, Bolan E, Xu M, Pasternak GW. Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene. Proc Natl Acad Sci U S A. 2001;98(24): 14084-14089.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 14084-14089
    • Pan, Y.X.1    Xu, J.2    Mahurter, L.3    Bolan, E.4    Xu, M.5    Pasternak, G.W.6
  • 17
    • 0037459104 scopus 로고    scopus 로고
    • Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X
    • Pan YX, Xu J, Mahurter L, Xu M, Gilbert AK, Pasternak GW. Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X. Biochem Biophys Res Commun. 2003;301(4):1057-1061.
    • (2003) Biochem Biophys Res Commun , vol.301 , Issue.4 , pp. 1057-1061
    • Pan, Y.X.1    Xu, J.2    Mahurter, L.3    Xu, M.4    Gilbert, A.K.5    Pasternak, G.W.6
  • 18
    • 34249794271 scopus 로고    scopus 로고
    • Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
    • Reyes-Gibby CC, Shete S, Rakvåg T, et al. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain. 2007;130(1-2):25-30.
    • (2007) Pain , vol.130 , Issue.1-2 , pp. 25-30
    • Reyes-Gibby, C.C.1    Shete, S.2    Rakvåg, T.3
  • 19
    • 0032530473 scopus 로고    scopus 로고
    • Age, pain intensity, and opioid dose in patients with advanced cancer
    • Viganó A, Bruera E, Suarez-Almazor ME. Age, pain intensity, and opioid dose in patients with advanced cancer. Cancer. 1998;83(6):1244-1250.
    • (1998) Cancer , vol.83 , Issue.6 , pp. 1244-1250
    • Viganó, A.1    Bruera, E.2    Suarez-Almazor, M.E.3
  • 21
  • 22
    • 34548443321 scopus 로고    scopus 로고
    • The use of opioid analgesia in end-stage renal disease patients managed without dialysis: Recommendations for practice
    • Murtagh FE, Chai MO, Donohoe P, Edmonds PM, Higginson IJ. The use of opioid analgesia in end-stage renal disease patients managed without dialysis: recommendations for practice. J Pain Palliat Care Pharmacother. 2007;21(2):5-16.
    • (2007) J Pain Palliat Care Pharmacother , vol.21 , Issue.2 , pp. 5-16
    • Murtagh, F.E.1    Chai, M.O.2    Donohoe, P.3    Edmonds, P.M.4    Higginson, I.J.5
  • 24
    • 67650736252 scopus 로고    scopus 로고
    • Opioid metabolism
    • Smith HS. Opioid metabolism. Mayo Clin Proc. 2009;84(7):613-624.
    • (2009) Mayo Clin Proc , vol.84 , Issue.7 , pp. 613-624
    • Smith, H.S.1
  • 25
    • 42549113996 scopus 로고    scopus 로고
    • Advisory Committee for Oxycodone Study. Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: An open-label trial
    • Narabayashi M, Saijo Y, Takenoshita S, et al; Advisory Committee for Oxycodone Study. Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: an open-label trial. Jpn J Clin Oncol. 2008;38(4):296-304.
    • (2008) Jpn J Clin Oncol , vol.38 , Issue.4 , pp. 296-304
    • Narabayashi, M.1    Saijo, Y.2    Takenoshita, S.3
  • 26
    • 31044445939 scopus 로고    scopus 로고
    • No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients
    • Riley J, Ross JR, Rutter D, et al. No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients. Support Care Cancer. 2006; 14(1):56-64.
    • (2006) Support Care Cancer , vol.14 , Issue.1 , pp. 56-64
    • Riley, J.1    Ross, J.R.2    Rutter, D.3
  • 27
    • 22544447819 scopus 로고    scopus 로고
    • Japan Pain, Rehabilitation, Palliative Medicine, and Psycho-Oncology (PRPP) Study Group. Opioid rotation from morphine to fentanyl in delirious cancer patients: An open-label trial
    • Morita T, Takigawa C, Onishi H, et al; Japan Pain, Rehabilitation, Palliative Medicine, and Psycho-Oncology (PRPP) Study Group. Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial. J Pain Symptom Manage. 2005;30(1): 96-103.
    • (2005) J Pain Symptom Manage , vol.30 , Issue.1 , pp. 96-103
    • Morita, T.1    Takigawa, C.2    Onishi, H.3
  • 28
    • 33846635073 scopus 로고    scopus 로고
    • Efficacy and safety of OPANA ER (oxymorphone extended release) for relief of moderate to severe chronic low back pain in opioid-experienced patients: A 12-week, randomized, double-blind, placebo-controlled study
    • Oxymorphone ER Study Group 1
    • Hale ME, Ahdieh H, Ma T, Rauck R; Oxymorphone ER Study Group 1. Efficacy and safety of OPANA ER (oxymorphone extended release) for relief of moderate to severe chronic low back pain in opioid-experienced patients: a 12-week, randomized, double-blind, placebo-controlled study. J Pain. 2007;8(2):175-184.
    • (2007) J Pain , vol.8 , Issue.2 , pp. 175-184
    • Hale, M.E.1    Ahdieh, H.2    Ma, T.3    Rauck, R.4
  • 30
    • 84954175035 scopus 로고    scopus 로고
    • Silver Spring, MD: US Food and Drug Administration, December 9, 2011
    • Rappaport BA. New Drug Application Approval Letter. Silver Spring, MD: US Food and Drug Administration. http://www.accessdata.fda.gov/drugsatfdadocs/appletter/2011/201655Orig1s000Ltr.pdf. December 9, 2011.
    • New Drug Application Approval Letter
    • Rappaport, B.A.1
  • 31
    • 84863447316 scopus 로고    scopus 로고
    • Strategies to reduce the tampering and subsequent abuse of long-acting opioids: Potential risks and benefits of formulations with physical or pharmacologic deterrents to tampering
    • Stanos SP, Bruckenthal P, Barkin RL. Strategies to reduce the tampering and subsequent abuse of long-acting opioids: potential risks and benefits of formulations with physical or pharmacologic deterrents to tampering. Mayo Clin Proc. 2012;87(7):683-694.
    • (2012) Mayo Clin Proc , vol.87 , Issue.7 , pp. 683-694
    • Stanos, S.P.1    Bruckenthal, P.2    Barkin, R.L.3
  • 32
    • 33745514619 scopus 로고    scopus 로고
    • Psychiatric and pain characteristics of prescription drug abusers entering drug rehabilitation
    • Passik SD, Hays L, Eisner N, Kirsh KL. Psychiatric and pain characteristics of prescription drug abusers entering drug rehabilitation. J Pain Palliat Care Pharmacother. 2006;20(2):5-13.
    • (2006) J Pain Palliat Care Pharmacother , vol.20 , Issue.2 , pp. 5-13
    • Passik, S.D.1    Hays, L.2    Eisner, N.3    Kirsh, K.L.4
  • 33
    • 84863429937 scopus 로고    scopus 로고
    • US Food and Drug Administration; US Department of Health and Human Services, press release, Released April 5, 2010. Accessed July 19, 2012
    • US Food and Drug Administration; US Department of Health and Human Services. FDA approves new formulation for OxyContin [press release]. http://www.fda.gov/NewsEvents/Newsroom/PressAnnounce-ments/ucm207480.htm. Released April 5, 2010. Accessed July 19, 2012.
    • FDA Approves New Formulation For OxyContin
  • 34
  • 35
    • 84876552357 scopus 로고    scopus 로고
    • OxyContin® (oxycodone HCl controlled-release tablets) [package insert]. Stamford, CT: Purdue Pharma L.P.; 2011
    • OxyContin® (oxycodone HCl controlled-release tablets) [package insert]. Stamford, CT: Purdue Pharma L.P.; 2011.
  • 36
    • 80054118887 scopus 로고    scopus 로고
    • Abuse risks and routes of administration of different prescription opioid compounds and formulations
    • Butler SF, Black RA, Cassidy TA, Dailey TM, Budman SH. Abuse risks and routes of administration of different prescription opioid compounds and formulations. Harm Reduct J. 2011;8(1):29.
    • (2011) Harm Reduct J , vol.8 , Issue.1 , pp. 29
    • Butler, S.F.1    Black, R.A.2    Cassidy, T.A.3    Dailey, T.M.4    Budman, S.H.5
  • 37
    • 44949084623 scopus 로고    scopus 로고
    • Abuse-deterrent opioid formulations: Are they a pipe dream?
    • Katz N. Abuse-deterrent opioid formulations: are they a pipe dream? Curr Rheumatol Rep. 2008;10(1):11-18.
    • (2008) Curr Rheumatol Rep , vol.10 , Issue.1 , pp. 11-18
    • Katz, N.1
  • 38
    • 84867769666 scopus 로고    scopus 로고
    • Effects of reformulated OxyContin® among patients assessed for substance abuse treatment in the NAVIP-PRO sentinal surveillance network
    • Black R, Coplan P, Cassidy T, et al. Effects of reformulated OxyContin® among patients assessed for substance abuse treatment in the NAVIP-PRO sentinal surveillance network. J Pain. 2012;13(4 suppl):S58.
    • (2012) J Pain , vol.13 , Issue.SUPPL 4
    • Black, R.1    Coplan, P.2    Cassidy, T.3
  • 39
    • 84863677170 scopus 로고    scopus 로고
    • Effect of abuse-deterrent formulation of OxyContin
    • Cicero TJ, Ellis MS, Surratt HL. Effect of abuse-deterrent formulation of OxyContin. N Engl J Med. 2012;367(2):187-189.
    • (2012) N Engl J Med , vol.367 , Issue.2 , pp. 187-189
    • Cicero, T.J.1    Ellis, M.S.2    Surratt, H.L.3
  • 40
    • 84864253851 scopus 로고    scopus 로고
    • Opioid extended-release tablets with improved tamper-resistant properties
    • Bartholomaeus J, Arkenau-Mari E, Galia E. Opioid extended-release tablets with improved tamper-resistant properties. Expert Opin Drug Deliv. 2012;9(8):879-891.
    • (2012) Expert Opin Drug Deliv , vol.9 , Issue.8 , pp. 879-891
    • Bartholomaeus, J.1    Arkenau-Mari, E.2    Galia, E.3
  • 41
    • 84867881321 scopus 로고    scopus 로고
    • Assessment of a formulation designed to be crush-resistant in prescription opioid abusers
    • published online ahead of print June 20
    • Vosburg SK, Jones JD, Manubay JM, Ashworth JB, Benedek IH, Comer SD. Assessment of a formulation designed to be crush-resistant in prescription opioid abusers [published online ahead of print June 20, 2012]. Drug Alcohol Depend.
    • (2012) Drug Alcohol Depend
    • Vosburg, S.K.1    Jones, J.D.2    Manubay, J.M.3    Ashworth, J.B.4    Benedek, I.H.5    Comer, S.D.6
  • 42
    • 84859152253 scopus 로고    scopus 로고
    • Bioequivalence of oxymor-phone extended release and crush-resistant oxymorphone extended release
    • Benedek IH, Jobes J, Xiang Q, Fiske WD. Bioequivalence of oxymor-phone extended release and crush-resistant oxymorphone extended release. Drug Des Devel Ther. 2011;5:455-463.
    • (2011) Drug Des Devel Ther , vol.5 , pp. 455-463
    • Benedek, I.H.1    Jobes, J.2    Xiang, Q.3    Fiske, W.D.4
  • 43
    • 77949917186 scopus 로고    scopus 로고
    • ALO-01 (morphine sulfate and naltrexone hydrochloride) extended-release capsules in the treatment of chronic pain of osteoarthritis of the hip or knee: Pharmacokinetics, efficacy, and safety
    • Katz N, Sun S, Johnson F, Stauffer J. ALO-01 (morphine sulfate and naltrexone hydrochloride) extended-release capsules in the treatment of chronic pain of osteoarthritis of the hip or knee: pharmacokinetics, efficacy, and safety. J Pain. 2010;11(4):303-311.
    • (2010) J Pain , vol.11 , Issue.4 , pp. 303-311
    • Katz, N.1    Sun, S.2    Johnson, F.3    Stauffer, J.4
  • 44
    • 77954644065 scopus 로고    scopus 로고
    • Relative oral bioavailability of morphine and naltrexone derived from crushed morphine sulfate and naltrexone hydrochloride extended-release capsules versus intact product and versus naltrexone solution: A single-dose, randomized-sequence, open-label, three-way crossover trial in healthy volunteers
    • Johnson FK, Stark JG, Bieberdorf FA, Stauffer J. Relative oral bioavailability of morphine and naltrexone derived from crushed morphine sulfate and naltrexone hydrochloride extended-release capsules versus intact product and versus naltrexone solution: a single-dose, randomized-sequence, open-label, three-way crossover trial in healthy volunteers. Clin Ther. 2010;32(6): 1149-1164.
    • (2010) Clin Ther , vol.32 , Issue.6 , pp. 1149-1164
    • Johnson, F.K.1    Stark, J.G.2    Bieberdorf, F.A.3    Stauffer, J.4
  • 45
    • 70449426117 scopus 로고    scopus 로고
    • Subjective effects and safety of whole and tampered morphine sulfate and naltrexone hydrochloride (ALO-01) extended-release capsules versus morphine solution and placebo in experienced non-dependent opioid users: A randomized, double-blind, placebo-controlled, crossover study
    • Stauffer J, Setnik B, Sokolowska M, Romach M, Johnson F, Sellers E. Subjective effects and safety of whole and tampered morphine sulfate and naltrexone hydrochloride (ALO-01) extended-release capsules versus morphine solution and placebo in experienced non-dependent opioid users: a randomized, double-blind, placebo-controlled, crossover study. Clin Drug Investig. 2009;29(12): 777-790.
    • (2009) Clin Drug Investig , vol.29 , Issue.12 , pp. 777-790
    • Stauffer, J.1    Setnik, B.2    Sokolowska, M.3    Romach, M.4    Johnson, F.5    Sellers, E.6
  • 46
    • 79960879545 scopus 로고    scopus 로고
    • Impact of intravenous naltrexone on intravenous morphine-induced high, drug liking, and euphoric effects in experienced, nondependent male opioid users
    • Webster LR, Johnson FK, Stauffer J, Setnik B, Ciric S. Impact of intravenous naltrexone on intravenous morphine-induced high, drug liking, and euphoric effects in experienced, nondependent male opioid users. Drugs R D. 2011;11(3):259-275.
    • (2011) Drugs R D , vol.11 , Issue.3 , pp. 259-275
    • Webster, L.R.1    Johnson, F.K.2    Stauffer, J.3    Setnik, B.4    Ciric, S.5
  • 47
    • 77956640307 scopus 로고    scopus 로고
    • Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain
    • Katz N, Hale M, Morris D, Stauffer J. Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain. Postgrad Med. 2010;122(4):112-128.
    • (2010) Postgrad Med , vol.122 , Issue.4 , pp. 112-128
    • Katz, N.1    Hale, M.2    Morris, D.3    Stauffer, J.4
  • 48
    • 78349272369 scopus 로고    scopus 로고
    • Long-term safety and efficacy of morphine sulfate and naltrexone hydrochloride extended release capsules, a novel formulation containing morphine and sequestered naltrexone, in patients with chronic, moderate to severe pain
    • Webster LR, Brewer R, Wang C, et al. Long-term safety and efficacy of morphine sulfate and naltrexone hydrochloride extended release capsules, a novel formulation containing morphine and sequestered naltrexone, in patients with chronic, moderate to severe pain. J Pain Symptom Manage. 2010;40(5):734-746.
    • (2010) J Pain Symptom Manage , vol.40 , Issue.5 , pp. 734-746
    • Webster, L.R.1    Brewer, R.2    Wang, C.3
  • 49
    • 76549093421 scopus 로고    scopus 로고
    • Severe opioid withdrawal due to misuse of new combined morphine and naltrexone product (Embeda)
    • Jang DH, Rohe JC, Hoffman RS, Nelson LS. Severe opioid withdrawal due to misuse of new combined morphine and naltrexone product (Embeda). Ann Emerg Med. 2010;55(3):303-304.
    • (2010) Ann Emerg Med , vol.55 , Issue.3 , pp. 303-304
    • Jang, D.H.1    Rohe, J.C.2    Hoffman, R.S.3    Nelson, L.S.4
  • 50
    • 77957313928 scopus 로고    scopus 로고
    • Acute opioid withdrawal precipitated by ingestion of crushed Embeda (morphine extended release with sequestered naltrexone): Case report and the focused review of the literature
    • Ruan X, Chen T, Gudin J, Couch JP, Chiravuri S. Acute opioid withdrawal precipitated by ingestion of crushed Embeda (morphine extended release with sequestered naltrexone): case report and the focused review of the literature. J Opioid Manag. 2010;6(4):300-303.
    • (2010) J Opioid Manag , vol.6 , Issue.4 , pp. 300-303
    • Ruan, X.1    Chen, T.2    Gudin, J.3    Couch, J.P.4    Chiravuri, S.5
  • 51
    • 84876551549 scopus 로고    scopus 로고
    • www.AboutLawsuits.com, Saiontz and Kirk, PA, Published March 16, 2011. Accessed July 19, 2012
    • www.AboutLawsuits.com. Embeda recall issued due to ongoing manufacturing problems. Saiontz and Kirk, PA. http://www.aboutlaw-suits.com/embeda-recall-manufacturing-problems-16891/. Published March 16, Accessed July 19, 2012.
    • (2011) Embeda Recall Issued Due to Ongoing Manufacturing Problems
  • 52
    • 84876527705 scopus 로고    scopus 로고
    • [package insert]. Bristol, TN: King Pharmaceuticals, Inc
    • OXECTA® (oxycodone HCl, USP) [package insert]. Bristol, TN: King Pharmaceuticals, Inc.; 2011.
    • (2011) OXECTA® (oxycodone HCl, USP)
  • 53
    • 33644505488 scopus 로고    scopus 로고
    • Development and validation of an Opioid Attractiveness Scale: A novel measure of the attractiveness of opioid products to potential abusers
    • Butler SF, Benoit C, Budman SH, et al. Development and validation of an Opioid Attractiveness Scale: a novel measure of the attractiveness of opioid products to potential abusers. Harm Reduct J. 2006;3:5.
    • (2006) Harm Reduct J , vol.3 , pp. 5
    • Butler, S.F.1    Benoit, C.2    Budman, S.H.3
  • 54
    • 74049118066 scopus 로고    scopus 로고
    • Estimating attractiveness for abuse of a not-yet-marketed "abuse-deterrent" prescription opioid formulation
    • Butler SF, Black R, Grimes Serrano JM, Folensbee L, Chang A, Katz N. Estimating attractiveness for abuse of a not-yet-marketed "abuse-deterrent" prescription opioid formulation. Pain Med. 2010;11(1):81-91.
    • (2010) Pain Med , vol.11 , Issue.1 , pp. 81-91
    • Butler, S.F.1    Black, R.2    Grimes Serrano, J.M.3    Folensbee, L.4    Chang, A.5    Katz, N.6
  • 56
    • 33749252978 scopus 로고    scopus 로고
    • Geneva, Switzerland: The World Health Organization
    • WHO Model List of Essential Medicines. Vol 17. Geneva, Switzerland: The World Health Organization; 2011.
    • (2011) WHO Model List of Essential Medicines , vol.17
  • 58
    • 33847303944 scopus 로고    scopus 로고
    • International Association for Hospice and Palliative Care list of essential medicines for palliative care
    • De Lima L. International Association for Hospice and Palliative Care list of essential medicines for palliative care. Ann Oncol. 2007;18(2):395-399.
    • (2007) Ann Oncol , vol.18 , Issue.2 , pp. 395-399
    • de Lima, L.1
  • 59
    • 84876525168 scopus 로고    scopus 로고
    • [package insert]. Chadds Ford, PA: Endo Pharmaceuticals Inc
    • OPANA® ER (oxymorphone hydrochloride) [package insert]. Chadds Ford, PA: Endo Pharmaceuticals Inc.; 2012.
    • (2012) OPANA® ER (oxymorphone hydrochloride)
  • 63
    • 84862564230 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of the abuse potential of different formulations of oral oxycodone
    • Webster LR, Bath B, Medve RA, Marmon T, Stoddard GJ. Randomized, double-blind, placebo-controlled study of the abuse potential of different formulations of oral oxycodone. Pain Med. 2012;13(6):790-801.
    • (2012) Pain Med , vol.13 , Issue.6 , pp. 790-801
    • Webster, L.R.1    Bath, B.2    Medve, R.A.3    Marmon, T.4    Stoddard, G.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.