-
1
-
-
34547852667
-
Extended-release opioids for the management of chronic non-malignant pain
-
Sloan P, Babul N. Extended-release opioids for the management of chronic non-malignant pain. Expert Opin Drug Deliv 2006; 3 (4): 489-97
-
(2006)
Expert Opin. Drug. Deliv.
, vol.3
, Issue.4
, pp. 489-497
-
-
Sloan, P.1
Babul, N.2
-
2
-
-
2342418441
-
Use and abuse of opioid analgesics: Potential methods to prevent and deter non-medical consumption of prescription opioids
-
Woolf CJ, Hashmi M. Use and abuse of opioid analgesics: potential methods to prevent and deter non-medical consumption of prescription opioids. Curr Opin Investig Drugs 2004; 5 (1): 61-6
-
(2004)
Curr. Opin. Investig Drugs
, vol.5
, Issue.1
, pp. 61-66
-
-
Woolf, C.J.1
Hashmi, M.2
-
3
-
-
84855977343
-
-
National Institute on Drug Abuse (NIDA) online]. Available from URL: [Accessed Apr 21
-
National Institute on Drug Abuse (NIDA). Prescription medications, NIDA news [online]. Available from URL: http://www.nida.nih.gov/DrugPages/ prescription.html [Accessed 2009 Apr 21]
-
(2009)
Prescription Medications NIDA News
-
-
-
4
-
-
84855919563
-
Results from the 2008 national survey on drug use and health: National findings
-
Substance Abuse and Mental Health Services Administration HHS publication no. (SMA) online 09- 4434. Rockville (MD). Available from URL:Accessed 2009 Oct 2
-
Substance Abuse and Mental Health Services Administration. Results from the 2008 National Survey on Drug Use and Health: national findings [online]. Office of Applied Studies, NSDUH Series H-36, HHS publication no. (SMA) 09-4434. Rockville (MD). Available from URL: http:// oas.samhsa.gov [Accessed 2009 Oct 2]
-
Office of Applied Studies NSDUH Series H-36
-
-
-
5
-
-
68449083154
-
-
Substance Abuse and Mental Health Services Administration. Office of Applied Studies DAWN Series D-30
-
Substance Abuse and Mental Health Services Administration. Drug Abuse Warning Network, 2006: national estimates of drug-related emergency department visits [online]. Office of Applied Studies, DAWN Series D-30, DHHS publication no. (SMA) 08-4339. Rockville (MD). Available from URL: http://dawninfo.samhsa. gov [Accessed 2010 Aug 1]
-
Drug Abuse Warning Network 2006: National Estimates of Drug-related Emergency Department Visits
-
-
-
6
-
-
84855982470
-
Treatment of episode data set TEDS highlights: 2006 national admissions to substance abuse treatment services
-
Substance Abuse and Mental Health Services Administration online DHHS publication no. (SMA) 08- 4313. Rockville (MD). Available from URL: [Accessed 2010 Aug 1
-
Substance Abuse and Mental Health Services Administration. Treatment of episode data set (TEDS) highlights: 2006; national admissions to substance abuse treatment services [online]. Office of Applied Studies, DASIS Series: S-40, DHHS publication no. (SMA) 08-4313. Rockville (MD). Available from URL: http://oas.samhsa.gov [Accessed 2010 Aug 1]
-
Office of Applied Studies DASIS Series: S-40
-
-
-
7
-
-
57449112519
-
Patterns of abuse among unintentional pharmaceutical overdose fatalities
-
Hall AJ, Logan JE, Toblin RL, et al. Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA 2008; 300 (22): 2613-20
-
(2008)
JAMA
, vol.300
, Issue.22
, pp. 2613-2620
-
-
Hall, A.J.1
Logan, J.E.2
Toblin, R.L.3
-
8
-
-
0003658008
-
-
Bethesda (MD): National Institute on Drug Abuse, US Department of Health and Human Services, 2009. NIH publication no. 09-7401
-
Johnston LD, O'Malley PM, Bachman JG, et al. Monitoring the future: national results on adolescent drug use; overview of key findings, 2008. Bethesda (MD): National Institute on Drug Abuse, US Department of Health and Human Services, 2009. NIH publication no. 09-7401
-
(2008)
Monitoring the Future: National Results on Adolescent Drug use; Overview of Key Findings 2008
-
-
Johnston, L.D.1
O'Malley, P.M.2
Bachman, J.G.3
-
9
-
-
33646029117
-
Risk identification, risk assessment, and risk management of abusable drug formulations
-
Wright IV C, Kramer ED, Zalman MA, et al. Risk identification, risk assessment, and risk management of abusable drug formulations. Drug Alcohol Depend 2006; 83 (Suppl. 1): S68-76
-
(2006)
Drug Alcohol. Depend.
, vol.83
, Issue.1
-
-
Wright IV, C.1
Kramer, E.D.2
Zalman, M.A.3
-
10
-
-
33846423929
-
Opioid prescriptions soar: Increase in legitimate use as well as abuse
-
Kuehn BM. Opioid prescriptions soar: increase in legitimate use as well as abuse. JAMA 2007; 297 (3): 249-51
-
(2007)
JAMA
, vol.297
, Issue.3
, pp. 249-251
-
-
Kuehn, B.M.1
-
11
-
-
44949084623
-
Abuse-deterrent opioid formulations: Are they a pipe dream
-
Katz N. Abuse-deterrent opioid formulations: are they a pipe dream? Curr Rheumatol Rep 2008; 10 (1): 11-8
-
(2008)
Curr. Rheumatol. Rep.
, vol.10
, Issue.1
, pp. 11-18
-
-
Katz, N.1
-
12
-
-
34648813683
-
Challenges in the development of prescription opioid abuse-deterrent formulations
-
Katz NP, Adams EH, Chilcoat H, et al. Challenges in the development of prescription opioid abuse-deterrent formulations. Clin J Pain 2007; 23 (8): 648-60
-
(2007)
Clin. J. Pain
, vol.23
, Issue.8
, pp. 648-660
-
-
Katz, N.P.1
Adams, E.H.2
Chilcoat, H.3
-
13
-
-
33646068382
-
Research design strategies to evaluate the impact of formulations on abuse liability
-
McColl S, Sellers EM. Research design strategies to evaluate the impact of formulations on abuse liability. Drug Alcohol Depend 2006; 83 (Suppl. 1): S52-62
-
(2006)
Drug. Alcohol. Depend.
, vol.83
, Issue.1
-
-
McColl, S.1
Sellers, E.M.2
-
14
-
-
80052727865
-
-
House of Representatives September 30,to accompany H.R. 2744),109th Congress, 1st Session
-
House of Representatives. Making appropriations for Agriculture, Rural Development, Food and Drug Administration, and related agencies programs for the fiscal year ending September 30, 2006, and for other purposes: conference report (to accompany H.R. 2744), 109-255; 109th Congress, 1st Session, 2005
-
(2005)
Making Appropriations for Agriculture Rural Development Food and Drug Administrationand Related Agencies Programs for the fiscal year ending 2006 and for other purposes: Conference report
, pp. 109-255
-
-
-
16
-
-
0003564810
-
-
National Center for Injury Prevention and Control,USDepartment ofHealth and Human Services (statement of Leonard J Paulozzi, MD, MPH, medical epidemiologist). Trends in unintentional drug overdose deaths before the Senate Judiciary Subcommittee on Crime and Drugs (Mar 12)
-
National Center for Injury Prevention and Control, Centers forDisease Control and Prevention,USDepartment ofHealth and Human Services (statement of Leonard J Paulozzi, MD, MPH, medical epidemiologist). Trends in unintentional drug overdose deaths before the Senate Judiciary Subcommittee on Crime and Drugs (2008 Mar 12)
-
(2008)
Centers forDisease Control and Prevention
-
-
-
17
-
-
0023975281
-
Naltrexone: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence
-
Gonzalez JP, Brogden RN. Naltrexone: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence. Drugs 1988; 35 (3): 192-213
-
(1988)
Drugs
, vol.35
, Issue.3
, pp. 192-213
-
-
Gonzalez, J.P.1
Brogden, R.N.2
-
19
-
-
33845660632
-
-
Frazer (PA): Cephalon Inc.
-
Vivitrol [package insert]. Frazer (PA): Cephalon Inc., 2007
-
(2007)
Vivitrol package insert
-
-
-
20
-
-
77957310939
-
-
Bristol (TN): King Pharmaceuticals Inc., June
-
EMBEDA- [package insert]. Bristol (TN): King Pharmaceuticals Inc., June 2009
-
(2009)
EMBEDA- package insert
-
-
-
21
-
-
70449426117
-
Subjective effects and safety of whole and tampered morphine sulfate and naltrexone hydrochloride ALO-01 extended-release capsules versus morphine solution and placebo in experienced non-dependent opioid users: A randomized double-blind placebo-controlled crossover study
-
Stauffer J, Setnik B, Sokolowska M, et al. Subjective effects and safety of whole and tampered morphine sulfate and naltrexone hydrochloride (ALO-01) extended-release capsules versus morphine solution and placebo in experienced non-dependent opioid users: a randomized, double-blind, placebo-controlled, crossover study. Clin Drug Investig 2009; 29 (12): 777-90
-
(2009)
Clin. Drug Investig
, vol.29
, Issue.12
, pp. 777-790
-
-
Stauffer, J.1
Setnik, B.2
Sokolowska, M.3
-
22
-
-
77954644065
-
Relative oral bioavailability of morphine and naltrexone derived from crushed morphine sulfate and naltrexone hydrochloride extended-release capsules versus intact product and versus naltrexone solution: A single-dose randomized-sequence open-label three-way crossover trial in healthy volunteers
-
Johnson FK, Stark JG, Bieberdorf FA, et al. Relative oral bioavailability of morphine and naltrexone derived from crushed morphine sulfate and naltrexone hydrochloride extended-release capsules versus intact product and versus naltrexone solution: a single-dose, randomized-sequence, open-label, three-way crossover trial in healthy volunteers. Clin Ther 2010; 32 (6): 1149-64
-
(2010)
Clin. Ther.
, vol.32
, Issue.6
, pp. 1149-1164
-
-
Johnson, F.K.1
Stark, J.G.2
Bieberdorf, F.A.3
-
23
-
-
0020467490
-
Assessment of the abuse liability of buspirone in recreational sedative users
-
Cole JO, Orzack MH, Beake B, et al. Assessment of the abuse liability of buspirone in recreational sedative users. J Clin Psychiatry 1982; 43 (12 Pt 2): 69-75
-
(1982)
J. Clin. Psychiatry
, vol.43
, Issue.12 PART 2
, pp. 69-75
-
-
Cole, J.O.1
Orzack, M.H.2
Beake, B.3
-
24
-
-
34548283471
-
Relationship between therapeutic use and abuse of opioid analgesics in rural suburban and urban locations in the United States
-
Cicero TJ, Surratt H, Inciardi JA, et al. Relationship between therapeutic use and abuse of opioid analgesics in rural, suburban, and urban locations in the United States. Pharmacoepidemiol Drug Saf 2007; 16 (8): 827-40
-
(2007)
Pharmacoepidemiol Drug. Saf.
, vol.16
, Issue.8
, pp. 827-840
-
-
Cicero, T.J.1
Surratt, H.2
Inciardi, J.A.3
-
25
-
-
84855969542
-
-
International Conference on Harmonisation online European Medicines Agency. Available from URL Accessed Aug 1]
-
International Conference on Harmonisation. ICH Topic E 6 (R1) guideline for good clinical practice [online]. European Medicines Agency. Available from URL: . emea.europa.eu/pdfs/human/ich/013595en.pdf [Accessed 2010 Aug 1]
-
(2010)
ICH Topic E 6 R1 guideline for good clinical practice
-
-
-
26
-
-
77951897524
-
-
World Medical Association (WMA). [online]. Available from URL:http://www.wma.net/en/30publications/10policies/b3/index.html [Accessed Jan 5]
-
World Medical Association (WMA). WMA Declaration of Helsinki: ethical principles for medical research involving human subjects [online]. Available from URL: http:// www.wma.net/en/30publications/10policies/b3/index.html [Accessed 2011 Jan 5]
-
(2011)
WMA Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects
-
-
-
27
-
-
0000369784
-
Assessment of the abuse potentiality of morphinelike drugs methods used in man
-
Martin W R, editor. New York (NY): Springer-Verlag
-
Jasinski DR. Assessment of the abuse potentiality of morphinelike drugs (methods used in man). In: Martin W R, editor. Drug Addiction. New York (NY): Springer-Verlag, 1977: 197-258
-
(1977)
Drug Addiction
, pp. 197-258
-
-
Jasinski, D.R.1
-
28
-
-
74549183490
-
Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone
-
Shram MJ, Sathyan G, Khanna S, et al. Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone. J Clin Psychopharmacol 2010; 30 (1): 25-33
-
(2010)
J. Clin. Psychopharmacol.
, vol.30
, Issue.1
, pp. 25-33
-
-
Shram, M.J.1
Sathyan, G.2
Khanna, S.3
-
29
-
-
3042651661
-
The papillary effects of intravenous morphine codeine and tramadol in volunteers
-
Knaggs RD, Crighton IM, Cobby TF, et al. The papillary effects of intravenous morphine, codeine, and tramadol in volunteers. Anesth Analg 2004; 99 (1): 108-12
-
(2004)
Anesth Analg
, vol.99
, Issue.1
, pp. 108-112
-
-
Knaggs, R.D.1
Crighton, I.M.2
Cobby, T.F.3
-
30
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Series B 1995; 57 (1): 289-300
-
(1995)
J. Royal. Stat. Soc. Series B
, vol.57
, Issue.1
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
31
-
-
80051499508
-
-
Natick (MA): Analgesic Solutions
-
Data on file. Natick (MA): Analgesic Solutions, 2011
-
(2011)
Data on File
-
-
-
32
-
-
0032786572
-
Evaluation of the opioid addiction test in an out-patient drug dependency unit
-
Ghodse AH, Greaves JL, Lynch D. Evaluation of the opioid addiction test in an out-patient drug dependency unit. Br J Psychiatry 1999; 175: 158-62
-
(1999)
Br. J. Psychiatry
, vol.175
, pp. 158-162
-
-
Ghodse, A.H.1
Greaves, J.L.2
Lynch, D.3
-
33
-
-
21244448805
-
The effects of tramadol on static and dynamic pupillometry in healthy subjects: The relationship between pharmacodynamics pharmacokinetics and CYP2D6 metaboliser status
-
Fliegert F, Kurth B, Gö hler K. The effects of tramadol on static and dynamic pupillometry in healthy subjects: the relationship between pharmacodynamics, pharmacokinetics and CYP2D6 metaboliser status. Eur J Clin Pharmacol 2005; 61 (4): 257-66
-
(2005)
Eur. J. Clin. Pharmacol.
, vol.61
, Issue.4
, pp. 257-266
-
-
Fliegert, F.1
Kurth, B.2
Göhler, K.3
-
34
-
-
77957374297
-
Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: Abuse potential and relative potencies
-
Stoops WW, Hatton KW, Lofwall MR, et al. Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: abuse potential and relative potencies. Psychopharmacology (Berl) 2010; 212 (2): 193-203
-
(2010)
Psychopharmacology Berl
, vol.212
, Issue.2
, pp. 193-203
-
-
Stoops, W.W.1
Hatton, K.W.2
Lofwall, M.R.3
-
35
-
-
0037648825
-
Guidelines and methodological reviews concerning drug abuse liability assessment
-
Balster RL, Bigelow GE. Guidelines and methodological reviews concerning drug abuse liability assessment. Drug Alcohol Depend 2003; 70 (3 Suppl.): S13-40
-
(2003)
Drug. Alcohol. Depend.
, vol.70
, Issue.3
-
-
Balster, R.L.1
Bigelow, G.E.2
-
36
-
-
0028231931
-
Opioid physical dependence development: Effects of single versus repeated morphine pretreatments and of subjects' opioid exposure history
-
Azolosa JL, Stitzer ML, Greenwald MK. Opioid physical dependence development: effects of single versus repeated morphine pretreatments and of subjects' opioid exposure history. Psychopharmacology (Berl) 1994; 114 (1): 71-80
-
(1994)
Psychopharmacology Berl
, vol.114
, Issue.1
, pp. 71-80
-
-
Azolosa, J.L.1
Stitzer, M.L.2
Greenwald, M.K.3
-
37
-
-
78649648381
-
-
US Department of Health and Human Services, FDA Rockville (MD): US Department of Health and Human Services,online]. Available from URL: [Accessed 2011Jul 17
-
US Department of Health and Human Services, FDA. Guidance for industry: assessment of abuse potential of drugs. Rockville (MD): US Department of Health and Human Services, 2010 [online]. Available from URL: http://www.fda.gov/cder/ guidance/index.htm [Accessed 2011Jul 17]
-
(2010)
Guidance for Industry: Assessment of Abuse Potential of Drugs
-
-
-
38
-
-
84855921470
-
-
National Advisory Council on Drug Abuse NACDA online]. Available from URL: Accessed Aug 1
-
National Advisory Council on Drug Abuse (NACDA). NACDA guidelines for administration of drugs to human subjects [online]. Available from URL: . gov/funding/hsguide.html [Accessed 2010 Aug 1]
-
(2010)
NACDA Guidelines for Administration of Drugs to Human Subjects
-
-
-
39
-
-
0033822179
-
Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers
-
Dershwitz M, Walsh JL, Morishige RJ, et al. Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers. Anesthesiology 2000; 93 (3): 619-28
-
(2000)
Anesthesiology
, vol.93
, Issue.3
, pp. 619-628
-
-
Dershwitz, M.1
Walsh, J.L.2
Morishige, R.J.3
-
40
-
-
0033991721
-
Illicit cocaine use patterns in intravenous-naive cocaine users following investigational intravenous cocaine administration
-
Kaufman MJ, Levin JM, Kukes TJ, et al. Illicit cocaine use patterns in intravenous-naive cocaine users following investigational intravenous cocaine administration. Drug Alcohol Depend 2000; 58 (1-2): 35-42
-
(2000)
Drug. Alcohol. Depend.
, vol.58
, Issue.1-2
, pp. 35-42
-
-
Kaufman, M.J.1
Levin, J.M.2
Kukes, T.J.3
-
41
-
-
58949087497
-
Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain
-
Chou R, Fanciullo GJ, Fine PG, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain 2009; 10 (2): 113-30
-
(2009)
J. Pain.
, vol.10
, Issue.2
, pp. 113-130
-
-
Chou, R.1
Fanciullo, G.J.2
Fine, P.G.3
|