Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 5, 2013, Pages 1905-1910

  Higgins, Matthew K ^a   Tkachenko, Olga ^b   Brown, Alan ^b   Reed, Jenny ^b   Raper, Jayne ^c   Carrington, Mark ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; HAPTOGLOBIN HEMOGLOBIN RECEPTOR; IMMUNOGLOBULIN; PROTEIN; PROTOZOAL PROTEIN; RECEPTOR; TRYPANOLYTIC FACTOR 1; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ALPHA HELIX; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; GENETIC POLYMORPHISM; INNATE IMMUNITY; LIGAND BINDING; MUTAGENESIS; NONHUMAN; NUTRIENT UPTAKE; PARASITE IMMUNITY; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN STRUCTURE; SMALL ANGLE SCATTERING; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CONGOLENSE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; ENDOCYTOSIS; HOST-PARASITE INTERACTIONS; HUMANS; IMMUNITY, INNATE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SCATTERING, SMALL ANGLE; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PLASMON RESONANCE; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE; TRYPANOSOMA CONGOLENSE; TRYPANOSOMIASIS, AFRICAN; VARIANT SURFACE GLYCOPROTEINS, TRYPANOSOMA; X-RAY DIFFRACTION;

EID: 84873175151     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214943110     Document Type: Article

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