-
1
-
-
13244284850
-
The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin
-
et al.
-
Johansen C, Kragballe K, Westergaard M, et al. The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin. Br J Dermatol 2005; 152: 37-42.
-
(2005)
Br J Dermatol
, vol.152
, pp. 37-42
-
-
Johansen, C.1
Kragballe, K.2
Westergaard, M.3
-
2
-
-
78649668321
-
Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFalpha therapy
-
et al.
-
Johansen C, Vinter H, Soegaard-Madsen L, et al. Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFalpha therapy. Br J Dermatol 2010; 163: 1194-204.
-
(2010)
Br J Dermatol
, vol.163
, pp. 1194-1204
-
-
Johansen, C.1
Vinter, H.2
Soegaard-Madsen, L.3
-
3
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J,. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001; 81: 807-69.
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
4
-
-
0036876857
-
Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis
-
et al.
-
Takahashi H, Ibe M, Nakamura S, et al. Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis. J Dermatol Sci 2002; 30: 94-9.
-
(2002)
J Dermatol Sci
, vol.30
, pp. 94-99
-
-
Takahashi, H.1
Ibe, M.2
Nakamura, S.3
-
5
-
-
36148934536
-
Expression and localization of the activated mitogen-activated protein kinase in lesional psoriatic skin
-
et al.
-
Yu XJ, Li CY, Dai HY, et al. Expression and localization of the activated mitogen-activated protein kinase in lesional psoriatic skin. Exp Mol Pathol 2007; 83: 413-18.
-
(2007)
Exp Mol Pathol
, vol.83
, pp. 413-418
-
-
Yu, X.J.1
Li, C.Y.2
Dai, H.Y.3
-
6
-
-
34248210189
-
Targeting dual-specificity phosphatases: Manipulating MAP kinase signalling and immune responses
-
et al.
-
Jeffrey KL, Camps M, Rommel C, et al. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov 2007; 6: 391-403.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 391-403
-
-
Jeffrey, K.L.1
Camps, M.2
Rommel, C.3
-
7
-
-
33746139320
-
Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines
-
et al.
-
Funding AT, Johansen C, Kragballe K, et al. Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines. J Invest Dermatol 2006; 126: 1784-91.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1784-1791
-
-
Funding, A.T.1
Johansen, C.2
Kragballe, K.3
-
8
-
-
34447534298
-
Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis
-
et al.
-
Funding AT, Johansen C, Kragballe K, et al. Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis. J Invest Dermatol 2007; 127: 2012-19.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2012-2019
-
-
Funding, A.T.1
Johansen, C.2
Kragballe, K.3
-
9
-
-
33751566645
-
DUSP meet immunology: Dual specificity MAPK phosphatases in control of the inflammatory response
-
Lang R, Hammer M, Mages J,. DUSP meet immunology: dual specificity MAPK phosphatases in control of the inflammatory response. J Immunol 2006; 177: 7497-504.
-
(2006)
J Immunol
, vol.177
, pp. 7497-7504
-
-
Lang, R.1
Hammer, M.2
Mages, J.3
-
10
-
-
0026779540
-
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
-
Keyse SM, Emslie EA,. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 1992; 359: 644-7.
-
(1992)
Nature
, vol.359
, pp. 644-647
-
-
Keyse, S.M.1
Emslie, E.A.2
-
11
-
-
34248679869
-
Dual-specificity phosphatase 1: A critical regulator of innate immune responses
-
Abraham SM, Clark AR,. Dual-specificity phosphatase 1: a critical regulator of innate immune responses. Biochem Soc Trans 2006; 34: 1018-23.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 1018-1023
-
-
Abraham, S.M.1
Clark, A.R.2
-
12
-
-
54049141728
-
Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer
-
Boutros T, Chevet E, Metrakos P,. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer. Pharmacol Rev 2008; 60: 261-310.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 261-310
-
-
Boutros, T.1
Chevet, E.2
Metrakos, P.3
-
13
-
-
31144452241
-
Essential role of MAPK phosphatase-1 in the negative control of innate immune responses
-
et al.
-
Salojin KV, Owusu IB, Millerchip KA, et al. Essential role of MAPK phosphatase-1 in the negative control of innate immune responses. J Immunol 2006; 176: 1899-907.
-
(2006)
J Immunol
, vol.176
, pp. 1899-1907
-
-
Salojin, K.V.1
Owusu, I.B.2
Millerchip, K.A.3
-
14
-
-
0029757347
-
Disruption of the erp/mkp-1 gene does not affect mouse development: Normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts
-
et al.
-
Dorfman K, Carrasco D, Gruda M, et al. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. Oncogene 1996; 13: 925-31.
-
(1996)
Oncogene
, vol.13
, pp. 925-931
-
-
Dorfman, K.1
Carrasco, D.2
Gruda, M.3
-
15
-
-
33847176551
-
MAPK phosphatases - Regulating the immune response
-
Liu Y, Shepherd EG, Nelin LD,. MAPK phosphatases-regulating the immune response. Nat Rev Immunol 2007; 7: 202-12.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 202-212
-
-
Liu, Y.1
Shepherd, E.G.2
Nelin, L.D.3
-
16
-
-
80051944472
-
Attenuation of the acute inflammatory response by dual specificity phosphatase 1 by inhibition of p38 MAP kinase
-
et al.
-
Korhonen R, Turpeinen T, Taimi V, et al. Attenuation of the acute inflammatory response by dual specificity phosphatase 1 by inhibition of p38 MAP kinase. Mol Immunol 2011; 48: 2059-68.
-
(2011)
Mol Immunol
, vol.48
, pp. 2059-2068
-
-
Korhonen, R.1
Turpeinen, T.2
Taimi, V.3
-
17
-
-
50849100743
-
Protecting the stress response, guarding the MKP-1 mRNA
-
Kuwano Y, Gorospe M,. Protecting the stress response, guarding the MKP-1 mRNA. Cell Cycle 2008; 7: 2640-2.
-
(2008)
Cell Cycle
, vol.7
, pp. 2640-2642
-
-
Kuwano, Y.1
Gorospe, M.2
-
18
-
-
33947699785
-
Modulation of mRNA stability as a novel therapeutic approach
-
et al.
-
Eberhardt W, Doller A, Akool el-S, et al. Modulation of mRNA stability as a novel therapeutic approach. Pharmacol Ther 2007; 114: 56-73.
-
(2007)
Pharmacol Ther
, vol.114
, pp. 56-73
-
-
Eberhardt, W.1
Doller, A.2
Akool, E.-S.3
-
19
-
-
31144448042
-
AU-rich elements and associated factors: Are there unifying principles?
-
Barreau C, Paillard L, Osborne HB,. AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res 2005; 33: 7138-50.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 7138-7150
-
-
Barreau, C.1
Paillard, L.2
Osborne, H.B.3
-
20
-
-
47049116117
-
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90
-
et al.
-
Kuwano Y, Kim HH, Abdelmohsen K, et al. MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol 2008; 28: 4562-75.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4562-4575
-
-
Kuwano, Y.1
Kim, H.H.2
Abdelmohsen, K.3
-
21
-
-
36049006140
-
Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells
-
Lin NY, Lin CT, Chang CJ,. Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells. Biochem Biophys Res Commun 2008; 365: 69-74.
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 69-74
-
-
Lin, N.Y.1
Lin, C.T.2
Chang, C.J.3
-
22
-
-
43449106240
-
Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases
-
et al.
-
Kjellerup RB, Kragballe K, Iversen L, et al. Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases. Exp Dermatol 2008; 17: 498-504.
-
(2008)
Exp Dermatol
, vol.17
, pp. 498-504
-
-
Kjellerup, R.B.1
Kragballe, K.2
Iversen, L.3
-
23
-
-
34547890303
-
Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): Possible role for its anti-psoriatic effect
-
et al.
-
Gesser B, Johansen C, Rasmussen MK, et al. Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect. J Invest Dermatol 2007; 127: 2129-37.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2129-2137
-
-
Gesser, B.1
Johansen, C.2
Rasmussen, M.K.3
-
24
-
-
77952677598
-
Adalimumab therapy rapidly inhibits p38 mitogen-activated protein kinase activity in lesional psoriatic skin preceding clinical improvement
-
et al.
-
Soegaard-Madsen L, Johansen C, Iversen L, et al. Adalimumab therapy rapidly inhibits p38 mitogen-activated protein kinase activity in lesional psoriatic skin preceding clinical improvement. Br J Dermatol 2010; 162: 1216-23.
-
(2010)
Br J Dermatol
, vol.162
, pp. 1216-1223
-
-
Soegaard-Madsen, L.1
Johansen, C.2
Iversen, L.3
-
25
-
-
71949086202
-
The expression and phosphorylation of eukaryotic initiation factor 4E are increased in lesional psoriatic skin
-
Kjellerup RB, Iversen L, Kragballe K, Johansen C,. The expression and phosphorylation of eukaryotic initiation factor 4E are increased in lesional psoriatic skin. Br J Dermatol 2009; 161: 1059-66.
-
(2009)
Br J Dermatol
, vol.161
, pp. 1059-1066
-
-
Kjellerup, R.B.1
Iversen, L.2
Kragballe, K.3
Johansen, C.4
-
26
-
-
50049086910
-
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
-
et al.
-
Ananieva O, Darragh J, Johansen C, et al. The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. Nat Immunol 2008; 9: 1028-36.
-
(2008)
Nat Immunol
, vol.9
, pp. 1028-1036
-
-
Ananieva, O.1
Darragh, J.2
Johansen, C.3
-
27
-
-
50049122380
-
The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression
-
et al.
-
Kim C, Sano Y, Todorova K, et al. The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression. Nat Immunol 2008; 9: 1019-27.
-
(2008)
Nat Immunol
, vol.9
, pp. 1019-1027
-
-
Kim, C.1
Sano, Y.2
Todorova, K.3
-
28
-
-
2342667386
-
Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins
-
et al.
-
Arthur JS, Fong AL, Dwyer JM, et al. Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. J Neurosci 2004; 24: 4324-32.
-
(2004)
J Neurosci
, vol.24
, pp. 4324-4332
-
-
Arthur, J.S.1
Fong, A.L.2
Dwyer, J.M.3
-
30
-
-
5644230846
-
Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: Up-regulation by interleukin-1beta and glucocorticoids
-
et al.
-
Toh ML, Yang Y, Leech M, et al. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids. Arthritis Rheum 2004; 50: 3118-28.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3118-3128
-
-
Toh, M.L.1
Yang, Y.2
Leech, M.3
-
31
-
-
0032512847
-
Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells
-
et al.
-
Guo YL, Baysal K, Kang B, et al. Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 1998; 273: 4027-34.
-
(1998)
J Biol Chem
, vol.273
, pp. 4027-4034
-
-
Guo, Y.L.1
Baysal, K.2
Kang, B.3
-
32
-
-
0036841288
-
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
-
et al.
-
Lasa M, Abraham SM, Boucheron C, et al. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol Cell Biol 2002; 22: 7802-11.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7802-7811
-
-
Lasa, M.1
Abraham, S.M.2
Boucheron, C.3
-
33
-
-
0032562781
-
Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells
-
Guo YL, Kang B, Williamson JR,. Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 1998; 273: 10362-6.
-
(1998)
J Biol Chem
, vol.273
, pp. 10362-10366
-
-
Guo, Y.L.1
Kang, B.2
Williamson, J.R.3
-
34
-
-
34548587913
-
Dexamethasone suppresses interleukin-1beta-induced human beta-defensin 2 mRNA expression: Involvement of p38 MAPK, JNK, MKP-1, and NF-kappaB transcriptional factor in A549 cells
-
et al.
-
Jang BC, Lim KJ, Suh MH, et al. Dexamethasone suppresses interleukin-1beta-induced human beta-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-kappaB transcriptional factor in A549 cells. FEMS Immunol Med Microbiol 2007; 51: 171-84.
-
(2007)
FEMS Immunol Med Microbiol
, vol.51
, pp. 171-184
-
-
Jang, B.C.1
Lim, K.J.2
Suh, M.H.3
-
35
-
-
58549099652
-
Glucocorticoids enhance Toll-like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokines
-
et al.
-
Shibata M, Katsuyama M, Onodera T, et al. Glucocorticoids enhance Toll-like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokines. J Invest Dermatol 2009; 129: 375-82.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 375-382
-
-
Shibata, M.1
Katsuyama, M.2
Onodera, T.3
-
36
-
-
31144468296
-
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2
-
et al.
-
Johansen C, Funding AT, Otkjaer K, et al. Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. J Immunol 2006; 176: 1431-8.
-
(2006)
J Immunol
, vol.176
, pp. 1431-1438
-
-
Johansen, C.1
Funding, A.T.2
Otkjaer, K.3
-
37
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
et al.
-
Davies SP, Reddy H, Caivano M, et al. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000; 351: 95-105.
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
-
38
-
-
77956200392
-
Cross-talk between the p38{alpha} and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation
-
et al.
-
Staples CJ, Owens DM, Maier JV, et al. Cross-talk between the p38{alpha} and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation. J Biol Chem 2010; 285: 25928-40.
-
(2010)
J Biol Chem
, vol.285
, pp. 25928-25940
-
-
Staples, C.J.1
Owens, D.M.2
Maier, J.V.3
-
39
-
-
78149460397
-
Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids
-
et al.
-
Shipp LE, Lee JV, Yu CY, et al. Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS ONE 2010; 5: e13754.
-
(2010)
PLoS ONE
, vol.5
-
-
Shipp, L.E.1
Lee, J.V.2
Yu, C.Y.3
-
40
-
-
0036829987
-
Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect
-
et al.
-
Xu Q, Konta T, Furusu A, et al. Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect. J Biol Chem 2002; 277: 41693-700.
-
(2002)
J Biol Chem
, vol.277
, pp. 41693-41700
-
-
Xu, Q.1
Konta, T.2
Furusu, A.3
-
41
-
-
51349120613
-
Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes
-
et al.
-
Lu TC, Wang Z, Feng X, et al. Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Mol Cell Biol 2008; 28: 5785-94.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5785-5794
-
-
Lu, T.C.1
Wang, Z.2
Feng, X.3
-
42
-
-
34447547568
-
Current and future management of psoriasis
-
Menter A, Griffiths CE,. Current and future management of psoriasis. Lancet 2007; 370: 272-84.
-
(2007)
Lancet
, vol.370
, pp. 272-284
-
-
Menter, A.1
Griffiths, C.E.2
|