-
1
-
-
33847279025
-
Pathogenesis and therapy of psoriasis
-
Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007 445 : 866 873.
-
(2007)
Nature
, vol.445
, pp. 866-873
-
-
Lowes, M.A.1
Bowcock, A.M.2
Krueger, J.G.3
-
2
-
-
42149195978
-
EIF4E, the mRNA cap-binding protein: From basic discovery to translational research
-
Sonenberg N. eIF4E, the mRNA cap-binding protein: from basic discovery to translational research. Biochem Cell Biol 2008 86 : 178 183.
-
(2008)
Biochem Cell Biol
, vol.86
, pp. 178-183
-
-
Sonenberg, N.1
-
3
-
-
0030041884
-
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
-
Rousseau D, Kaspar R, Rosenwald I et al. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci USA 1996 93 : 1065 1070.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1065-1070
-
-
Rousseau, D.1
Kaspar, R.2
Rosenwald, I.3
-
4
-
-
33846648989
-
Controlling gene expression through RNA regulons: The role of the eukaryotic translation initiation factor eIF4E
-
Culjkovic B, Topisirovic I, Borden KL. Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E. Cell Cycle 2007 6 : 65 9.
-
(2007)
Cell Cycle
, vol.6
, pp. 65-69
-
-
Culjkovic, B.1
Topisirovic, I.2
Borden, K.L.3
-
5
-
-
2342489456
-
EIF-4E expression and its role in malignancies and metastases
-
De Benedetti A, Graff JR. eIF-4E expression and its role in malignancies and metastases. Oncogene 2004 23 : 3189 3199.
-
(2004)
Oncogene
, vol.23
, pp. 3189-3199
-
-
De Benedetti, A.1
Graff, J.R.2
-
6
-
-
38849180436
-
Targeting the eukaryotic translation initiation factor 4E for cancer therapy
-
Graff JR, Konicek BW, Carter JH et al. Targeting the eukaryotic translation initiation factor 4E for cancer therapy. Cancer Res 2008 68 : 631 634.
-
(2008)
Cancer Res
, vol.68
, pp. 631-634
-
-
Graff, J.R.1
Konicek, B.W.2
Carter, J.H.3
-
7
-
-
33750681957
-
EIF4E is a central node of an RNA regulon that governs cellular proliferation
-
Culjkovic B, Topisirovic I, Skrabanek L et al. eIF4E is a central node of an RNA regulon that governs cellular proliferation. J Cell Biol 2006 175 : 415 426.
-
(2006)
J Cell Biol
, vol.175
, pp. 415-426
-
-
Culjkovic, B.1
Topisirovic, I.2
Skrabanek, L.3
-
8
-
-
2342584183
-
EIF4E - From translation to transformation
-
Mamane Y, Petroulakis E, Rong L et al. eIF4E - from translation to transformation. Oncogene 2004 23 : 3172 3179.
-
(2004)
Oncogene
, vol.23
, pp. 3172-3179
-
-
Mamane, Y.1
Petroulakis, E.2
Rong, L.3
-
9
-
-
0036438924
-
Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?
-
Scheper GC, Proud CG. Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? Eur J Biochem 2002 269 : 5350 5359.
-
(2002)
Eur J Biochem
, vol.269
, pp. 5350-5359
-
-
Scheper, G.C.1
Proud, C.G.2
-
10
-
-
0034668203
-
Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1
-
Pyronnet S. Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1. Biochem Pharmacol 2000 60 : 1237 1243.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1237-1243
-
-
Pyronnet, S.1
-
11
-
-
3242719457
-
Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development
-
Ueda T, Watanabe-Fukunaga R, Fukuyama H et al. Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development. Mol Cell Biol 2004 24 : 6539 6549.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6539-6549
-
-
Ueda, T.1
Watanabe-Fukunaga, R.2
Fukuyama, H.3
-
12
-
-
52049088725
-
The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)
-
Buxade M, Parra-Palau JL, Proud CG. The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases). Front Biosci 2008 13 : 5359 5373.
-
(2008)
Front Biosci
, vol.13
, pp. 5359-5373
-
-
Buxade, M.1
Parra-Palau, J.L.2
Proud, C.G.3
-
13
-
-
13244284850
-
The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin
-
Johansen C, Kragballe K, Westergaard M et al. The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin. Br J Dermatol 2005 152 : 37 42.
-
(2005)
Br J Dermatol
, vol.152
, pp. 37-42
-
-
Johansen, C.1
Kragballe, K.2
Westergaard, M.3
-
14
-
-
9244228003
-
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
-
Topisirovic I, Ruiz-Gutierrez M, Borden KL. Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res 2004 64 : 8639 8642.
-
(2004)
Cancer Res
, vol.64
, pp. 8639-8642
-
-
Topisirovic, I.1
Ruiz-Gutierrez, M.2
Borden, K.L.3
-
15
-
-
41849138637
-
MNK, EIF4E and targeting translation for therapy
-
Silva RL, Wendel HG. MNK, EIF4E and targeting translation for therapy. Cell Cycle 2008 7 : 553 555.
-
(2008)
Cell Cycle
, vol.7
, pp. 553-555
-
-
Silva, R.L.1
Wendel, H.G.2
-
16
-
-
43449106240
-
Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases
-
Kjellerup RB, Kragballe K, Iversen L et al. Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases. Exp Dermatol 2008 17 : 498 504.
-
(2008)
Exp Dermatol
, vol.17
, pp. 498-504
-
-
Kjellerup, R.B.1
Kragballe, K.2
Iversen, L.3
-
17
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 2004 18 : 1926 1945.
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
18
-
-
2942515128
-
Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells
-
Jiang H, Coleman J, Miskimins R et al. Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells. Cancer Cell Int 2003 3 : 2.
-
(2003)
Cancer Cell Int
, vol.3
, pp. 2
-
-
Jiang, H.1
Coleman, J.2
Miskimins, R.3
-
19
-
-
45749141224
-
Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs
-
Rong L, Livingstone M, Sukarieh R et al. Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. RNA 2008 14 : 1318 1327.
-
(2008)
RNA
, vol.14
, pp. 1318-1327
-
-
Rong, L.1
Livingstone, M.2
Sukarieh, R.3
-
20
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras AC, Raught B, Gygi SP et al. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev 2001 15 : 2852 2864.
-
(2001)
Genes Dev
, vol.15
, pp. 2852-2864
-
-
Gingras, A.C.1
Raught, B.2
Gygi, S.P.3
-
21
-
-
0037192868
-
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
-
Herbert TP, Tee AR, Proud CG. The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. J Biol Chem 2002 277 : 11591 11596.
-
(2002)
J Biol Chem
, vol.277
, pp. 11591-11596
-
-
Herbert, T.P.1
Tee, A.R.2
Proud, C.G.3
-
23
-
-
33750068623
-
MTOR, translation initiation and cancer
-
Mamane Y, Petroulakis E, LeBacquer O et al. mTOR, translation initiation and cancer. Oncogene 2006 25 : 6416 6422.
-
(2006)
Oncogene
, vol.25
, pp. 6416-6422
-
-
Mamane, Y.1
Petroulakis, E.2
Lebacquer, O.3
-
24
-
-
31144468296
-
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2
-
Johansen C, Funding AT, Otkjaer K et al. Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. J Immunol 2006 176 : 1431 1438.
-
(2006)
J Immunol
, vol.176
, pp. 1431-1438
-
-
Johansen, C.1
Funding, A.T.2
Otkjaer, K.3
-
25
-
-
0033768476
-
Defect in the regulation of 4E-BP1 and 2, two repressors of translation initiation, in the retinoid acid resistant cell lines, NB4-R1 and NB4-R2
-
Grolleau A, Wietzerbin J, Beretta L. Defect in the regulation of 4E-BP1 and 2, two repressors of translation initiation, in the retinoid acid resistant cell lines, NB4-R1 and NB4-R2. Leukemia 2000 14 : 1909 1914.
-
(2000)
Leukemia
, vol.14
, pp. 1909-1914
-
-
Grolleau, A.1
Wietzerbin, J.2
Beretta, L.3
-
26
-
-
0038143284
-
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1
-
Rolli-Derkinderen M, Machavoine F, Baraban JM et al. ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. J Biol Chem 2003 278 : 18859 18867.
-
(2003)
J Biol Chem
, vol.278
, pp. 18859-18867
-
-
Rolli-Derkinderen, M.1
MacHavoine, F.2
Baraban, J.M.3
-
27
-
-
0035182727
-
Creation of psoriatic plaques: The ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint
-
Nickoloff BJ. Creation of psoriatic plaques: the ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint. J Cutan Pathol 2001 28 : 57 64.
-
(2001)
J Cutan Pathol
, vol.28
, pp. 57-64
-
-
Nickoloff, B.J.1
-
28
-
-
35348954728
-
Translational control: A target for cancer therapy
-
Thumma SC, Kratzke RA. Translational control: a target for cancer therapy. Cancer Lett 2007 258 : 1 8.
-
(2007)
Cancer Lett
, vol.258
, pp. 1-8
-
-
Thumma, S.C.1
Kratzke, R.A.2
-
29
-
-
0027289462
-
Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc
-
Rosenwald IB, Rhoads DB, Callanan LD et al. Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc. Proc Natl Acad Sci USA 1993 90 : 6175 6178.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6175-6178
-
-
Rosenwald, I.B.1
Rhoads, D.B.2
Callanan, L.D.3
-
30
-
-
34250755685
-
Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
-
Mamane Y, Petroulakis E, Martineau Y et al. Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation. PLoS ONE 2007 2 : e242.
-
(2007)
PLoS ONE
, vol.2
, pp. 242
-
-
Mamane, Y.1
Petroulakis, E.2
Martineau, Y.3
-
31
-
-
0033387917
-
Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis
-
Bhushan M, McLaughlin B, Weiss JB et al. Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis. Br J Dermatol 1999 141 : 1054 1060.
-
(1999)
Br J Dermatol
, vol.141
, pp. 1054-1060
-
-
Bhushan, M.1
McLaughlin, B.2
Weiss, J.B.3
-
32
-
-
0027980960
-
Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
-
Detmar M, Brown LF, Claffey KP et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994 180 : 1141 1146.
-
(1994)
J Exp Med
, vol.180
, pp. 1141-1146
-
-
Detmar, M.1
Brown, L.F.2
Claffey, K.P.3
-
33
-
-
33750914270
-
Downregulation of the inhibitor of apoptosis protein survivin in keratinocytes and endothelial cells in psoriasis skin following infliximab therapy
-
Markham T, Mathews C, Rogers S et al. Downregulation of the inhibitor of apoptosis protein survivin in keratinocytes and endothelial cells in psoriasis skin following infliximab therapy. Br J Dermatol 2006 155 : 1191 1196.
-
(2006)
Br J Dermatol
, vol.155
, pp. 1191-1196
-
-
Markham, T.1
Mathews, C.2
Rogers, S.3
-
34
-
-
42049085112
-
Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study
-
Abdou AG, Hanout HM. Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study. J Cutan Pathol 2008 35 : 445 451.
-
(2008)
J Cutan Pathol
, vol.35
, pp. 445-451
-
-
Abdou, A.G.1
Hanout, H.M.2
-
35
-
-
0027491842
-
Increased expression of epidermal IL-8 receptor in psoriasis. Down-regulation by FK-506 in vitro
-
Schulz BS, Michel G, Wagner S et al. Increased expression of epidermal IL-8 receptor in psoriasis. Down-regulation by FK-506 in vitro. J Immunol 1993 151 : 4399 4406.
-
(1993)
J Immunol
, vol.151
, pp. 4399-4406
-
-
Schulz, B.S.1
Michel, G.2
Wagner, S.3
-
36
-
-
0025245828
-
Growth factor and proto-oncogene expression in psoriasis
-
Elder LT, Klein SB, Tavakkol A et al. Growth factor and proto-oncogene expression in psoriasis. J Invest Dermatol 1990 95 : S7 9.
-
(1990)
J Invest Dermatol
, vol.95
, pp. 7-9
-
-
Elder, L.T.1
Klein, S.B.2
Tavakkol, A.3
-
37
-
-
0025126905
-
Expression of c-myc protein in skin and synovium in psoriasis and psoriatic arthritis
-
Osterland CK, Wilkinson RD, St Louis EA. Expression of c-myc protein in skin and synovium in psoriasis and psoriatic arthritis. Clin Exp Rheumatol 1990 8 : 145 150.
-
(1990)
Clin Exp Rheumatol
, vol.8
, pp. 145-150
-
-
Osterland, C.K.1
Wilkinson, R.D.2
St Louis, E.A.3
-
39
-
-
0026705268
-
A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus
-
Lejbkowicz F, Goyer C, Darveau A et al. A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus. Proc Natl Acad Sci USA 1992 89 : 9612 9616.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9612-9616
-
-
Lejbkowicz, F.1
Goyer, C.2
Darveau, A.3
-
40
-
-
0035839002
-
Coupled transcription and translation within nuclei of mammalian cells
-
Iborra FJ, Jackson DA, Cook PR. Coupled transcription and translation within nuclei of mammalian cells. Science 2001 293 : 1139 1142.
-
(2001)
Science
, vol.293
, pp. 1139-1142
-
-
Iborra, F.J.1
Jackson, D.A.2
Cook, P.R.3
-
41
-
-
9644274337
-
Suppression of human Mnk1 by small interfering RNA increases the eukaryotic initiation factor 4F activity in HEK293T cells
-
O'Loghlen A, Gonzalez VM, Salinas M et al. Suppression of human Mnk1 by small interfering RNA increases the eukaryotic initiation factor 4F activity in HEK293T cells. FEBS Lett 2004 578 : 31 5.
-
(2004)
FEBS Lett
, vol.578
, pp. 31-5
-
-
O'Loghlen, A.1
Gonzalez, V.M.2
Salinas, M.3
-
43
-
-
33645706120
-
Expression of genes involved in the regulation of p16 in psoriatic involved skin
-
Mark EB, Jonsson M, Asp J et al. Expression of genes involved in the regulation of p16 in psoriatic involved skin. Arch Dermatol Res 2006 297 : 459 467.
-
(2006)
Arch Dermatol Res
, vol.297
, pp. 459-467
-
-
Mark, E.B.1
Jonsson, M.2
Asp, J.3
|