메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages 13-22

Herbal hepatotoxicity: A hidden epidemic

Author keywords

Dietary supplement (DS); Hepatotoxicity; Herbal remedies (HRs); Prevention; Slimming aids

Indexed keywords


EID: 84873154377     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-012-0777-x     Document Type: Review
Times cited : (62)

References (80)
  • 2
    • 0035899915 scopus 로고    scopus 로고
    • Herbal medicine today and the roots of modern pathology
    • Goldman P (2001) Herbal medicine today and the roots of modern pathology. Ann Intern Med 135: 594-600.
    • (2001) Ann Intern Med , vol.135 , pp. 594-600
    • Goldman, P.1
  • 3
    • 33947282103 scopus 로고    scopus 로고
    • Herbal medicine in the treatment of liver diseases
    • Stickel F, Schuppan D (2007) Herbal medicine in the treatment of liver diseases. Dig Liver Dis 39: 293-304.
    • (2007) Dig Liver Dis , vol.39 , pp. 293-304
    • Stickel, F.1    Schuppan, D.2
  • 4
    • 42449162940 scopus 로고    scopus 로고
    • European legislation on herbal medicines: a look into the future
    • Calapai G (2008) European legislation on herbal medicines: a look into the future. Drug Saf 31: 428-431.
    • (2008) Drug Saf , vol.31 , pp. 428-431
    • Calapai, G.1
  • 7
    • 70449133964 scopus 로고    scopus 로고
    • Herbal and dietary supplement hepatotoxicity
    • Navarro V (2009) Herbal and dietary supplement hepatotoxicity. Sem Liv Dis 29: 3733-3782.
    • (2009) Sem Liv Dis , vol.29 , pp. 3733-3782
    • Navarro, V.1
  • 9
    • 0027362542 scopus 로고
    • Causality assessment of adverse reactions to drugs-I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries
    • Danan G, Benichou C (1993) Causality assessment of adverse reactions to drugs-I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol 46: 1323-1330.
    • (1993) J Clin Epidemiol , vol.46 , pp. 1323-1330
    • Danan, G.1    Benichou, C.2
  • 10
    • 0030865914 scopus 로고    scopus 로고
    • Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis
    • Maria VA, Victorino RM (1997) Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis. Hepatology 26: 664-669.
    • (1997) Hepatology , vol.26 , pp. 664-669
    • Maria, V.A.1    Victorino, R.M.2
  • 11
    • 10644251758 scopus 로고    scopus 로고
    • Validity study of a new diagnostic scale for drug-induced liver injury in Japan-comparison with two previous scales
    • Watanabe M, Shibuya A (2004) Validity study of a new diagnostic scale for drug-induced liver injury in Japan-comparison with two previous scales. Hepatol Res 30: 148-154.
    • (2004) Hepatol Res , vol.30 , pp. 148-154
    • Watanabe, M.1    Shibuya, A.2
  • 13
    • 0032508952 scopus 로고    scopus 로고
    • Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey
    • Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, van Rompay M et al (1998) Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 280: 1569-1575.
    • (1998) Jama , vol.280 , pp. 1569-1575
    • Eisenberg, D.M.1    Davis, R.B.2    Ettner, S.L.3    Appel, S.4    Wilkey, S.5    van Rompay, M.6
  • 15
    • 77951198234 scopus 로고    scopus 로고
    • National Institute of Statistic, Rome: ISTAT
    • National Institute of Statistic (2007) Le terapie non convenzionali in Italia. ISTAT, Rome.
    • (2007) Le Terapie Non Convenzionali in Italia
  • 16
    • 79954440143 scopus 로고    scopus 로고
    • Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health
    • Vitalone A, Menniti-Ippolito F, Moro PA, Firenzuoli F, Raschetti R et al (2011) Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health. Eur J Clin Pharmacol 67: 215-224.
    • (2011) Eur J Clin Pharmacol , vol.67 , pp. 215-224
    • Vitalone, A.1    Menniti-Ippolito, F.2    Moro, P.A.3    Firenzuoli, F.4    Raschetti, R.5
  • 18
    • 33744493938 scopus 로고    scopus 로고
    • Herbal products: behaviours and beliefs among Italian women
    • Zaffani S, Cuzzolin L, Benoni G (2006) Herbal products: behaviours and beliefs among Italian women. Pharmacoepidemiol Drug Saf 15: 354-359.
    • (2006) Pharmacoepidemiol Drug Saf , vol.15 , pp. 354-359
    • Zaffani, S.1    Cuzzolin, L.2    Benoni, G.3
  • 19
    • 0031680756 scopus 로고    scopus 로고
    • Abortifacient effects of lodgepole pine (Pinus contorta) and common juniper (Juniperus communis) on cattle
    • Gardner DR, Panter KE, James LF, Stegelmeier BL (1998) Abortifacient effects of lodgepole pine (Pinus contorta) and common juniper (Juniperus communis) on cattle. Vet Hum Toxicol 40: 260-263.
    • (1998) Vet Hum Toxicol , vol.40 , pp. 260-263
    • Gardner, D.R.1    Panter, K.E.2    James, L.F.3    Stegelmeier, B.L.4
  • 20
    • 77951554533 scopus 로고    scopus 로고
    • Imatinib and Panax ginseng: a potential interaction resulting in liver toxicity
    • Bilgi N, Bell K, Ananthakrishnan AN, Atallah E (2010) Imatinib and Panax ginseng: a potential interaction resulting in liver toxicity. Ann Pharmacother 44: 926-928.
    • (2010) Ann Pharmacother , vol.44 , pp. 926-928
    • Bilgi, N.1    Bell, K.2    Ananthakrishnan, A.N.3    Atallah, E.4
  • 21
    • 38749119778 scopus 로고    scopus 로고
    • Echinacea-induced severe acute hepatitis with features of cholestatic autoimmune hepatitis
    • Kocaman O, Hulagu S, Senturk O (2008) Echinacea-induced severe acute hepatitis with features of cholestatic autoimmune hepatitis. Eur J Intern Med 19: 148.
    • (2008) Eur J Intern Med , vol.19 , pp. 148
    • Kocaman, O.1    Hulagu, S.2    Senturk, O.3
  • 25
    • 79953329974 scopus 로고    scopus 로고
    • Review of liver injury associated with dietary supplements
    • Stickel F, Kessebohm K, Weimann R, Seitz HK (2011) Review of liver injury associated with dietary supplements. Liver Int 31: 595-605.
    • (2011) Liver Int , vol.31 , pp. 595-605
    • Stickel, F.1    Kessebohm, K.2    Weimann, R.3    Seitz, H.K.4
  • 26
    • 31644435641 scopus 로고    scopus 로고
    • Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins
    • Galati G, Lin A, Sultan AM, O'Brien PJ (2006) Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radic Biol Med 40: 570-580.
    • (2006) Free Radic Biol Med , vol.40 , pp. 570-580
    • Galati, G.1    Lin, A.2    Sultan, A.M.3    O'Brien, P.J.4
  • 27
    • 47949091916 scopus 로고    scopus 로고
    • Green tea consumption and liver disease: a systematic review
    • Jin X, Zheng RH, Li YM (2008) Green tea consumption and liver disease: a systematic review. Liver Int 28: 990-996.
    • (2008) Liver Int , vol.28 , pp. 990-996
    • Jin, X.1    Zheng, R.H.2    Li, Y.M.3
  • 28
    • 35348923465 scopus 로고    scopus 로고
    • Tea and cancer prevention: molecular mechanisms and human relevance
    • Yang CS, Lambert JD, Ju J, Lu G, Sang S (2007) Tea and cancer prevention: molecular mechanisms and human relevance. Toxicol Appl Pharmacol 224: 265-273.
    • (2007) Toxicol Appl Pharmacol , vol.224 , pp. 265-273
    • Yang, C.S.1    Lambert, J.D.2    Ju, J.3    Lu, G.4    Sang, S.5
  • 29
    • 0007633983 scopus 로고
    • Veno-occlusive disease of the liver secondary to ingestion of comfrey
    • Weston CFM, Cooper BT, Davies JD, Levine DF (1987) Veno-occlusive disease of the liver secondary to ingestion of comfrey. BMJ 295: 183.
    • (1987) Bmj , vol.295 , pp. 183
    • Weston, C.F.M.1    Cooper, B.T.2    Davies, J.D.3    Levine, D.F.4
  • 30
    • 0034506455 scopus 로고    scopus 로고
    • The efficacy and safety of comfrey
    • Stickel F, Seitz HK (2000) The efficacy and safety of comfrey. Pub Health Nutr 3: 501-508.
    • (2000) Pub Health Nutr , vol.3 , pp. 501-508
    • Stickel, F.1    Seitz, H.K.2
  • 31
    • 0025723960 scopus 로고
    • The use of medicinal herbs by human immunodeficiency virus-infected patients
    • Kassler WJ, Blanc P, Greenblatt R (1991) The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 151: 2281-2288.
    • (1991) Arch Intern Med , vol.151 , pp. 2281-2288
    • Kassler, W.J.1    Blanc, P.2    Greenblatt, R.3
  • 33
    • 0025802729 scopus 로고
    • Nordihydroguaiaretic acid, an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes
    • Agarwal R, Wang ZY, Bik DP, Mukhtar H (1991) Nordihydroguaiaretic acid, an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes. Drug Metab Dispos 19: 620-624.
    • (1991) Drug Metab Dispos , vol.19 , pp. 620-624
    • Agarwal, R.1    Wang, Z.Y.2    Bik, D.P.3    Mukhtar, H.4
  • 34
    • 0001920936 scopus 로고    scopus 로고
    • Valerian for insomnia: a systematic review of randomized clinical trials
    • Stevinson C, Ernst E (2000) Valerian for insomnia: a systematic review of randomized clinical trials. Sleep Med 1: 91-99.
    • (2000) Sleep Med , vol.1 , pp. 91-99
    • Stevinson, C.1    Ernst, E.2
  • 36
    • 54549103229 scopus 로고    scopus 로고
    • A case of valerian-associated hepatotoxicity
    • Cohen DL, Del Toro Y (2008) A case of valerian-associated hepatotoxicity. J Clin Gastroenterol 42: 961-962.
    • (2008) J Clin Gastroenterol , vol.42 , pp. 961-962
    • Cohen, D.L.1    Del Toro, Y.2
  • 38
    • 84873167535 scopus 로고    scopus 로고
    • Severe drug induced acute hepatitis associated with use of St John's wort (Hypericum perforatum) during treatment with pegylated interferon α
    • doi: 10. 1136/bcr. 08. 2008. 0761
    • Piccolo P, Gentile S, Alegiani F, Angelico M (2009) Severe drug induced acute hepatitis associated with use of St John's wort (Hypericum perforatum) during treatment with pegylated interferon α. BMJ Case Rep. doi: 10. 1136/bcr. 08. 2008. 0761.
    • (2009) BMJ Case Rep
    • Piccolo, P.1    Gentile, S.2    Alegiani, F.3    Angelico, M.4
  • 39
    • 42949142612 scopus 로고    scopus 로고
    • Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction?
    • Etogo-Asse F, Boemer F, Sempoux C, Geubel A (2008) Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction? Acta Gastroenterol Belg 71: 36-38.
    • (2008) Acta Gastroenterol Belg , vol.71 , pp. 36-38
    • Etogo-Asse, F.1    Boemer, F.2    Sempoux, C.3    Geubel, A.4
  • 40
    • 0036257022 scopus 로고    scopus 로고
    • Herbal hepatotoxicity
    • Stedman C (2002) Herbal hepatotoxicity. Semin Liver Dis 22: 195-206.
    • (2002) Semin Liver Dis , vol.22 , pp. 195-206
    • Stedman, C.1
  • 44
    • 56349138698 scopus 로고    scopus 로고
    • Kava hepatotoxicity: a clinical survey and critical analysis of 26 suspected cases
    • Teschke R, Schwarzenboeck A, Hennermann KH (2008) Kava hepatotoxicity: a clinical survey and critical analysis of 26 suspected cases. Eur J Gastroenterol Hepatol 20: 1182-1193.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 1182-1193
    • Teschke, R.1    Schwarzenboeck, A.2    Hennermann, K.H.3
  • 46
    • 78349260262 scopus 로고    scopus 로고
    • Kava hepatotoxicity-a clinical review
    • Teschke R (2010) Kava hepatotoxicity-a clinical review. Ann Hepatol 9: 251-265.
    • (2010) Ann Hepatol , vol.9 , pp. 251-265
    • Teschke, R.1
  • 47
    • 78349273977 scopus 로고    scopus 로고
    • Kava hepatotoxicity: pathogenetic aspects and prospective considerations
    • Teschke R (2010) Kava hepatotoxicity: pathogenetic aspects and prospective considerations. Liver Int 30: 1270-1279.
    • (2010) Liver Int , vol.30 , pp. 1270-1279
    • Teschke, R.1
  • 48
    • 0030087560 scopus 로고    scopus 로고
    • Pharmacological activities of Chelidonium majus L. (Papaveraceae)
    • Colombo ML, Bosisio E (1996) Pharmacological activities of Chelidonium majus L. (Papaveraceae). Pharmacol Res 33: 127-134.
    • (1996) Pharmacol Res , vol.33 , pp. 127-134
    • Colombo, M.L.1    Bosisio, E.2
  • 49
  • 51
    • 0011463954 scopus 로고    scopus 로고
    • Hepatotoxicity of herbal remedies
    • Larrey D (1997) Hepatotoxicity of herbal remedies. J Hepatol 26: 47-51.
    • (1997) J Hepatol , vol.26 , pp. 47-51
    • Larrey, D.1
  • 52
    • 0031881398 scopus 로고    scopus 로고
    • Toxicity of atractylosides in precicion-cut rat and porcine renal and hepatic tissue slices
    • Obatomi DK, Brant S, Anthony-Pillai V, Bach PH (1998) Toxicity of atractylosides in precicion-cut rat and porcine renal and hepatic tissue slices. Toxicol Appl Pharmacol 148: 35-45.
    • (1998) Toxicol Appl Pharmacol , vol.148 , pp. 35-45
    • Obatomi, D.K.1    Brant, S.2    Anthony-Pillai, V.3    Bach, P.H.4
  • 53
    • 34547912522 scopus 로고    scopus 로고
    • Black cohosh, safety, and public awareness
    • Dunbar K, Solga SF (2007) Black cohosh, safety, and public awareness. Liver Int 27: 1017-1018.
    • (2007) Liver Int , vol.27 , pp. 1017-1018
    • Dunbar, K.1    Solga, S.F.2
  • 54
    • 51449114460 scopus 로고    scopus 로고
    • United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity
    • Mahady GB, Low Dog T, Barrett ML, Chavez ML, Gardiner P, Ko R et al (2008) United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity. Menopause 15: 628-638.
    • (2008) Menopause , vol.15 , pp. 628-638
    • Mahady, G.B.1    Low Dog, T.2    Barrett, M.L.3    Chavez, M.L.4    Gardiner, P.5    Ko, R.6
  • 55
    • 84873175499 scopus 로고    scopus 로고
    • EMEA. Assessment of case reports connected to herbal medicinal products containing Cimicifugae racemosae rhizoma (black cohosh, root). Available at
    • EMEA. Assessment of case reports connected to herbal medicinal products containing Cimicifugae racemosae rhizoma (black cohosh, root). Available at: http://www. emea. europa. eu/pdfs/human/hmpc/.
  • 56
    • 77949379937 scopus 로고    scopus 로고
    • Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a diagnostic causality algorithm. A critical review
    • Teschke R (2010) Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a diagnostic causality algorithm. A critical review. Menopause 17: 426-440.
    • (2010) Menopause , vol.17 , pp. 426-440
    • Teschke, R.1
  • 57
    • 79251569237 scopus 로고    scopus 로고
    • Black cohosh hepatic safety: follow-up of 107 patients consuming a special Cimicifuga racemosa rhizome herbal extract and review of literature
    • doi: 10. 1093/ecam/nen009
    • Firenzuoli F, Gori L, di Sarsina PR (2011) Black cohosh hepatic safety: follow-up of 107 patients consuming a special Cimicifuga racemosa rhizome herbal extract and review of literature. Evid Based Complement Alternat Med. doi: 10. 1093/ecam/nen009.
    • (2011) Evid Based Complement Alternat Med
    • Firenzuoli, F.1    Gori, L.2    di Sarsina, P.R.3
  • 58
    • 84873116824 scopus 로고    scopus 로고
    • US Food and Drug Administration. Warning on Hydroxycut products. Available at
    • US Food and Drug Administration. Warning on Hydroxycut products. Available at http://www. fda. gov.
  • 59
    • 63449092588 scopus 로고    scopus 로고
    • Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements
    • Dara L, Hewett J, Lim JK (2008) Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol 14: 6999-7004.
    • (2008) World J Gastroenterol , vol.14 , pp. 6999-7004
    • Dara, L.1    Hewett, J.2    Lim, J.K.3
  • 61
    • 65649093745 scopus 로고    scopus 로고
    • Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance
    • Lobb A (2009) Hepatoxicity associated with weight-loss supplements: a case for better post-marketing surveillance. World J Gastroenterol 15: 1786-1787.
    • (2009) World J Gastroenterol , vol.15 , pp. 1786-1787
    • Lobb, A.1
  • 62
    • 0030038305 scopus 로고    scopus 로고
    • Acute hepatitis associated with the use of a chinese herbal product, Ma huang
    • Nadir A, Agrawal S, King P, King PD, Marshall JB (1996) Acute hepatitis associated with the use of a chinese herbal product, Ma huang. Am J Gastoenterol 91: 1436-1438.
    • (1996) Am J Gastoenterol , vol.91 , pp. 1436-1438
    • Nadir, A.1    Agrawal, S.2    King, P.3    King, P.D.4    Marshall, J.B.5
  • 63
    • 0035019355 scopus 로고    scopus 로고
    • Fulminant exacerbation of autoimmune hepatitis after the use of Ma huang
    • Borum ML (2001) Fulminant exacerbation of autoimmune hepatitis after the use of Ma huang. Am J Gastroenterol 96: 1654-1655.
    • (2001) Am J Gastroenterol , vol.96 , pp. 1654-1655
    • Borum, M.L.1
  • 64
    • 17844402272 scopus 로고    scopus 로고
    • Ma huang associated acute liver failure requiring liver transplantation
    • Skoulidis F, Alexander GJ, Davies SE (2005) Ma huang associated acute liver failure requiring liver transplantation. Eur J Gastroenterol Hepatol 17: 581-584.
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , pp. 581-584
    • Skoulidis, F.1    Alexander, G.J.2    Davies, S.E.3
  • 65
    • 0242486852 scopus 로고    scopus 로고
    • The irony of herbal hepatitis. Ma-huang induced hepatotoxicity associated with compound heterozygosity for hereditary hemochromatosis
    • Bajaj J, Knox JF, Komorowski R, Saeian K (2003) The irony of herbal hepatitis. Ma-huang induced hepatotoxicity associated with compound heterozygosity for hereditary hemochromatosis. Dig Dis Sci 48: 1925-1928.
    • (2003) Dig Dis Sci , vol.48 , pp. 1925-1928
    • Bajaj, J.1    Knox, J.F.2    Komorowski, R.3    Saeian, K.4
  • 68
    • 33645685192 scopus 로고    scopus 로고
    • Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid
    • Sanchez W, Maple JT, Burgart LJ, Kamath PS (2006) Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 81: 541-544.
    • (2006) Mayo Clin Proc , vol.81 , pp. 541-544
    • Sanchez, W.1    Maple, J.T.2    Burgart, L.J.3    Kamath, P.S.4
  • 69
    • 1242308775 scopus 로고    scopus 로고
    • Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress
    • Han D, Matsumaru K, Rettori D, Kaplowitz N (2004) Usnic acid-induced necrosis of cultured mouse hepatocytes: inhibition of mitochondrial function and oxidative stress. Biochem Pharmacol 67: 439-451.
    • (2004) Biochem Pharmacol , vol.67 , pp. 439-451
    • Han, D.1    Matsumaru, K.2    Rettori, D.3    Kaplowitz, N.4
  • 70
    • 81255185360 scopus 로고    scopus 로고
    • Two contemporary cases of hepatitis associated with Teucrium chamaedrys L. Decoction use. Case reports and review of literature
    • Gori L, Galluzzi P, Mascherini V, Gallo E, Lapi F et al (2011) Two contemporary cases of hepatitis associated with Teucrium chamaedrys L. Decoction use. Case reports and review of literature. Basic Clin Pharmacol Toxicol 109: 521-526.
    • (2011) Basic Clin Pharmacol Toxicol , vol.109 , pp. 521-526
    • Gori, L.1    Galluzzi, P.2    Mascherini, V.3    Gallo, E.4    Lapi, F.5
  • 72
    • 0029994146 scopus 로고    scopus 로고
    • Hepatotoxicity of the herbal medicine, germander, metabolic activation of its furano diterpenoids by cytochrome P450 3A depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes
    • Lekehal M, Pessayre D, Lereau JM, Moulis C, Fouraste I, Fau D (1996) Hepatotoxicity of the herbal medicine, germander, metabolic activation of its furano diterpenoids by cytochrome P450 3A depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes. Hepatology 24: 212-218.
    • (1996) Hepatology , vol.24 , pp. 212-218
    • Lekehal, M.1    Pessayre, D.2    Lereau, J.M.3    Moulis, C.4    Fouraste, I.5    Fau, D.6
  • 73
    • 34548212844 scopus 로고    scopus 로고
    • Association between consumption of Herbalifes nutritional supplements and acute hepatotoxicity
    • Elinav E, Pinsker G, Safadi R, Pappo O, Bromberg M, Anis E et al (2007) Association between consumption of Herbalifes nutritional supplements and acute hepatotoxicity. J Hepatol 47: 514-520.
    • (2007) J Hepatol , vol.47 , pp. 514-520
    • Elinav, E.1    Pinsker, G.2    Safadi, R.3    Pappo, O.4    Bromberg, M.5    Anis, E.6
  • 74
    • 34548286038 scopus 로고    scopus 로고
    • Herbal does not mean innocuous: 10 cases of severe hepatotoxicity associated with dietary supplements from Herbalifes products
    • Schoepfer AM, Engel A, Fattinger K, Marbet UA, Criblez D, Reichen J et al (2007) Herbal does not mean innocuous: 10 cases of severe hepatotoxicity associated with dietary supplements from Herbalifes products. J Hepatol 47: 521-526.
    • (2007) J Hepatol , vol.47 , pp. 521-526
    • Schoepfer, A.M.1    Engel, A.2    Fattinger, K.3    Marbet, U.A.4    Criblez, D.5    Reichen, J.6
  • 75
    • 33847706131 scopus 로고    scopus 로고
    • Hepatotoxicity associated with the consumption of herbal slimming products
    • Duque JM, Ferreiro J, Salgueiro E, Manso G (2007) Hepatotoxicity associated with the consumption of herbal slimming products. Med Clin (Barc) 128: 238-239.
    • (2007) Med Clin (Barc) , vol.128 , pp. 238-239
    • Duque, J.M.1    Ferreiro, J.2    Salgueiro, E.3    Manso, G.4
  • 77
    • 56949108345 scopus 로고    scopus 로고
    • Severe hepatotoxicity following ingestion of Herbalifes nutritional supplements contaminated with Bacillus subtilis
    • Stickel F, Droz S, Patsenker E, Bögli-Stuber K, Aebi B, Leib SL (2009) Severe hepatotoxicity following ingestion of Herbalifes nutritional supplements contaminated with Bacillus subtilis. J Hepatol 50: 111-117.
    • (2009) J Hepatol , vol.50 , pp. 111-117
    • Stickel, F.1    Droz, S.2    Patsenker, E.3    Bögli-Stuber, K.4    Aebi, B.5    Leib, S.L.6
  • 78
    • 77950287576 scopus 로고    scopus 로고
    • Hepatotoxicity associated with the use of Herbalife
    • Johannsson M, Ormarsdottir S, Olafsson S (2010) Hepatotoxicity associated with the use of Herbalife. Laeknabladid 96: 167-172.
    • (2010) Laeknabladid , vol.96 , pp. 167-172
    • Johannsson, M.1    Ormarsdottir, S.2    Olafsson, S.3
  • 79
    • 79952705842 scopus 로고    scopus 로고
    • Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum
    • Lin G, Wang JY, Li N, Gao H, Ji Y, Zhang F et al (2010) Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol 54: 666-673.
    • (2010) J Hepatol , vol.54 , pp. 666-673
    • Lin, G.1    Wang, J.Y.2    Li, N.3    Gao, H.4    Ji, Y.5    Zhang, F.6
  • 80
    • 79952699970 scopus 로고    scopus 로고
    • Herbal medicine hepatotoxicity: a new step with development of specific biomarkers
    • Larrey D, Faure S (2011) Herbal medicine hepatotoxicity: a new step with development of specific biomarkers. J Hepatol 54: 599-601.
    • (2011) J Hepatol , vol.54 , pp. 599-601
    • Larrey, D.1    Faure, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.