메뉴 건너뛰기




Volumn 10, Issue 1, 2013, Pages 68-76

Hematopoietic Stem Cell Therapy for Multiple Sclerosis: Top 10 Lessons Learned

Author keywords

Autoimmunity; Hematopoietic stem cell transplantation; Immune ablation; Multiple sclerosis

Indexed keywords

BUSULFAN; CLADRIBINE; CYCLOPHOSPHAMIDE; FINGOLIMOD; RITUXIMAB; THYMOCYTE ANTIBODY;

EID: 84873141923     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-012-0162-5     Document Type: Review
Times cited : (66)

References (71)
  • 1
    • 77954382272 scopus 로고    scopus 로고
    • Evidence for a two-stage disability progression in Multiple sclerosis
    • Leray E, Yaouanq J, Le Page E, et al. Evidence for a two-stage disability progression in Multiple sclerosis. Brain 2010; 133: 1900-1913.
    • (2010) Brain , vol.133 , pp. 1900-1913
    • Leray, E.1    Yaouanq, J.2    Le Page, E.3
  • 2
    • 84863895902 scopus 로고    scopus 로고
    • Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis
    • Shirani A, Zhao Y, Karim ME, et al. Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis. JAMA 2012; 308: 247-256.
    • (2012) Jama , vol.308 , pp. 247-256
    • Shirani, A.1    Zhao, Y.2    Karim, M.E.3
  • 3
    • 79952839371 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: have available therapies impacted long-term prognosis?
    • Trojano M, Paolicelli D, Tortorella C, et al. Natural history of multiple sclerosis: have available therapies impacted long-term prognosis? Neurol Clin 2011; 29: 309-321.
    • (2011) Neurol Clin , vol.29 , pp. 309-321
    • Trojano, M.1    Paolicelli, D.2    Tortorella, C.3
  • 4
    • 84994634473 scopus 로고    scopus 로고
    • Immunomodulatory therapies delay disease progression in multiple sclerosis
    • doi: 10. 1177/1352458512445941
    • Bergamaschi R, Quaglini S, Tavazzi E, et al. Immunomodulatory therapies delay disease progression in multiple sclerosis. Mult Scler 2012. doi: 10. 1177/1352458512445941.
    • (2012) Mult Scler
    • Bergamaschi, R.1    Quaglini, S.2    Tavazzi, E.3
  • 5
    • 0037153729 scopus 로고    scopus 로고
    • Mitoxantrone in Multiple Sclerosis Study Group (MIMS). Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial
    • Hartung HP, Gonsette R, König N, et al. Mitoxantrone in Multiple Sclerosis Study Group (MIMS). Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial. Lancet 2002; 360: 2018-2025.
    • (2002) Lancet , vol.360 , pp. 2018-2025
    • Hartung, H.P.1    Gonsette, R.2    König, N.3
  • 6
    • 77951828930 scopus 로고    scopus 로고
    • Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Evidence Report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    • Marriott JJ, Miyasaki JM, Gronseth G, O'Connor PW. Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Evidence Report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2010; 74: 1463-1470.
    • (2010) Neurology , vol.74 , pp. 1463-1470
    • Marriott, J.J.1    Miyasaki, J.M.2    Gronseth, G.3    O'Connor, P.W.4
  • 7
    • 0027329005 scopus 로고
    • Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation
    • Karussis DM, Vourka-Karussis U, Lehmann D, et al. Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation. J Clin Invest 1993; 92: 765-772.
    • (1993) J Clin Invest , vol.92 , pp. 765-772
    • Karussis, D.M.1    Vourka-Karussis, U.2    Lehmann, D.3
  • 8
    • 84862184679 scopus 로고    scopus 로고
    • Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation
    • Snowden JA, Saccardi R, Allez M, et al. Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2012; 47: 770-790.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 770-790
    • Snowden, J.A.1    Saccardi, R.2    Allez, M.3
  • 9
    • 84866174558 scopus 로고    scopus 로고
    • Transplantation for autoimmune diseases in north and south america: a report of the Center for International Blood and Marrow Transplant Research
    • Pasquini MC, Voltarelli J, Atkins HL, et al. Transplantation for autoimmune diseases in north and south america: a report of the Center for International Blood and Marrow Transplant Research. Biol Blood Marrow Transplant 2012; 18: 1471-1478.
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 1471-1478
    • Pasquini, M.C.1    Voltarelli, J.2    Atkins, H.L.3
  • 10
    • 0031723134 scopus 로고    scopus 로고
    • Stem cell transplantation for severe autoimmune diseases: progress and problems
    • Marmont AM. Stem cell transplantation for severe autoimmune diseases: progress and problems. Haematologica 1998; 83: 733-743.
    • (1998) Haematologica , vol.83 , pp. 733-743
    • Marmont, A.M.1
  • 11
    • 0032781764 scopus 로고    scopus 로고
    • Autologous peripheral blood stem cell transplantation in a patient with multiple sclerosis and concomitant Ph+ acute leukemia
    • Meloni G, Capria S, Salvetti M, et al. Autologous peripheral blood stem cell transplantation in a patient with multiple sclerosis and concomitant Ph+ acute leukemia. Haematologica 1999; 84: 665-667.
    • (1999) Haematologica , vol.84 , pp. 665-667
    • Meloni, G.1    Capria, S.2    Salvetti, M.3
  • 12
    • 0031053084 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis
    • McAllister LD, Beatty PG, Rose J. Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis. Bone Marrow Transplant 1997; 19: 395-397.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 395-397
    • McAllister, L.D.1    Beatty, P.G.2    Rose, J.3
  • 13
    • 0141816715 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Nash RA, Bowen JD, McSweeney PA, et al. High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Blood 2003; 102: 2364-2372.
    • (2003) Blood , vol.102 , pp. 2364-2372
    • Nash, R.A.1    Bowen, J.D.2    McSweeney, P.A.3
  • 14
    • 0141593519 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
    • Burt RK, Cohen BA, Russell E, et al. Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores. Blood 2003; 102: 2373-2378.
    • (2003) Blood , vol.102 , pp. 2373-2378
    • Burt, R.K.1    Cohen, B.A.2    Russell, E.3
  • 15
    • 0347264750 scopus 로고    scopus 로고
    • CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    • Carreras E, Saiz A, Marín P, et al. CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients. Haematologica 2003; 88: 306-314.
    • (2003) Haematologica , vol.88 , pp. 306-314
    • Carreras, E.1    Saiz, A.2    Marín, P.3
  • 16
    • 0034060611 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis
    • Kozák T, Havrdová E, Pit'ha J, et al. High-dose immunosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis. Bone Marrow Transplant 2000; 25: 525-531.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 525-531
    • Kozák, T.1    Havrdová, E.2    Pit'ha, J.3
  • 17
    • 0034093120 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in progressive multiple sclerosis-an interim analysis of efficacy
    • Fassas A, Anagnostopoulos A, Kazis A, et al. Autologous stem cell transplantation in progressive multiple sclerosis-an interim analysis of efficacy. J Clin Immunol 2000; 20: 24-30.
    • (2000) J Clin Immunol , vol.20 , pp. 24-30
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3
  • 18
    • 33846297365 scopus 로고    scopus 로고
    • Autoimmune Diseases Working Party of EBMT. Autologous stem cell transplantation for progressive multiple sclerosis: update of the European Group for Blood and Marrow Transplantation autoimmune diseases working party database
    • Saccardi R, Kozak T, Bocelli-Tyndall C, et al. Autoimmune Diseases Working Party of EBMT. Autologous stem cell transplantation for progressive multiple sclerosis: update of the European Group for Blood and Marrow Transplantation autoimmune diseases working party database. Mult Scler 2006; 12: 814-823.
    • (2006) Mult Scler , vol.12 , pp. 814-823
    • Saccardi, R.1    Kozak, T.2    Bocelli-Tyndall, C.3
  • 19
    • 78650209961 scopus 로고    scopus 로고
    • Hematopoietic SCT for the treatment of multiple sclerosis
    • Atkins H. Hematopoietic SCT for the treatment of multiple sclerosis. Bone Marrow Transplant 2010; 45: 1671-1681.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1671-1681
    • Atkins, H.1
  • 20
    • 49949093283 scopus 로고    scopus 로고
    • Autologous haematopoietic stem-cell transplantation in multiple sclerosis
    • Mancardi G, Saccardi R. Autologous haematopoietic stem-cell transplantation in multiple sclerosis. Lancet Neurol 2008; 7: 626-636.
    • (2008) Lancet Neurol , vol.7 , pp. 626-636
    • Mancardi, G.1    Saccardi, R.2
  • 21
    • 76549116862 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases
    • Farge D, Labopin M, Tyndall A, et al. Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Haematologica 2010; 95: 284-292.
    • (2010) Haematologica , vol.95 , pp. 284-292
    • Farge, D.1    Labopin, M.2    Tyndall, A.3
  • 22
    • 0034643935 scopus 로고    scopus 로고
    • Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor
    • Openshaw H, Stuve O, Antel JP, et al. Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor. Neurology 2000; 54: 2147-2150.
    • (2000) Neurology , vol.54 , pp. 2147-2150
    • Openshaw, H.1    Stuve, O.2    Antel, J.P.3
  • 23
    • 34247871288 scopus 로고    scopus 로고
    • The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes
    • Aboumrad E, Madec AM, Thivolet C. The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes. Clin Exp Immunol 2007; 148: 432-439.
    • (2007) Clin Exp Immunol , vol.148 , pp. 432-439
    • Aboumrad, E.1    Madec, A.M.2    Thivolet, C.3
  • 24
    • 79960837472 scopus 로고    scopus 로고
    • CXCL12 expression within the CNS contributes to the resistance against experimental autoimmune encephalomyelitis in Albino Oxford rats
    • Miljković D, Stanojević Z, Momcilović M, et al. CXCL12 expression within the CNS contributes to the resistance against experimental autoimmune encephalomyelitis in Albino Oxford rats. Immunobiology 2011; 216: 979-987.
    • (2011) Immunobiology , vol.216 , pp. 979-987
    • Miljković, D.1    Stanojević, Z.2    Momcilović, M.3
  • 25
    • 43549090004 scopus 로고    scopus 로고
    • The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans
    • Zohren F, Toutzaris D, Klärner V, Hartung HP, Kieseier B, Haas R. The monoclonal anti-VLA-4 antibody natalizumab mobilizes CD34+ hematopoietic progenitor cells in humans. Blood 2008; 111: 3893-3895.
    • (2008) Blood , vol.111 , pp. 3893-3895
    • Zohren, F.1    Toutzaris, D.2    Klärner, V.3    Hartung, H.P.4    Kieseier, B.5    Haas, R.6
  • 26
    • 43549101765 scopus 로고    scopus 로고
    • Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab
    • Bonig H, Wundes A, Chang KH, Lucas S, Papayannopoulou T. Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab. Blood 2008; 111: 3439-3441.
    • (2008) Blood , vol.111 , pp. 3439-3441
    • Bonig, H.1    Wundes, A.2    Chang, K.H.3    Lucas, S.4    Papayannopoulou, T.5
  • 27
    • 77957947043 scopus 로고    scopus 로고
    • CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function
    • Jing D, Oelschlaegel U, Ordemann R, et al. CD49d blockade by natalizumab in patients with multiple sclerosis affects steady-state hematopoiesis and mobilizes progenitors with a distinct phenotype and function. Bone Marrow Transplant 2010; 45: 1489-1496.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1489-1496
    • Jing, D.1    Oelschlaegel, U.2    Ordemann, R.3
  • 28
    • 80855156819 scopus 로고    scopus 로고
    • CD49d blockade by natalizumab therapy in patients with multiple sclerosis increases immature B-lymphocytes
    • Lesesve JF, Debouverie M, Decarvalho Bittencourt M, Béné MC. CD49d blockade by natalizumab therapy in patients with multiple sclerosis increases immature B-lymphocytes. Bone Marrow Transplant 2011; 46: 1489-1491.
    • (2011) Bone Marrow Transplant , vol.46 , pp. 1489-1491
    • Lesesve, J.F.1    Debouverie, M.2    Decarvalho Bittencourt, M.3    Béné, M.C.4
  • 29
    • 77953074174 scopus 로고    scopus 로고
    • Immune reconstitution: how it should work, what's broken, and why it matters
    • Gress RE, Emerson SG, Drobyski WR. Immune reconstitution: how it should work, what's broken, and why it matters. Biol Blood Marrow Transplant 2010; 16: S133-S137.
    • (2010) Biol Blood Marrow Transplant , vol.16
    • Gress, R.E.1    Emerson, S.G.2    Drobyski, W.R.3
  • 30
    • 33745627452 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation for progressive multiple sclerosis: report of efficacy and safety at three year of follow up in 21 patients
    • Ni XS, Ouyang J, Zhu WH, Wang C, Chen B. Autologous hematopoietic stem cell transplantation for progressive multiple sclerosis: report of efficacy and safety at three year of follow up in 21 patients. Clin Transplant 2006; 20: 485-489.
    • (2006) Clin Transplant , vol.20 , pp. 485-489
    • Ni, X.S.1    Ouyang, J.2    Zhu, W.H.3    Wang, C.4    Chen, B.5
  • 31
    • 0347264750 scopus 로고    scopus 로고
    • CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    • Carreras E, Saiz A, Marín P, et al. CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients. Haematologica 2003; 88: 306-314.
    • (2003) Haematologica , vol.88 , pp. 306-314
    • Carreras, E.1    Saiz, A.2    Marín, P.3
  • 32
    • 33750345757 scopus 로고    scopus 로고
    • Autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Su L, Xu J, Ji BX, et al. Autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Int J Hematol 2006; 84: 276-281.
    • (2006) Int J Hematol , vol.84 , pp. 276-281
    • Su, L.1    Xu, J.2    Ji, B.X.3
  • 33
    • 12344292442 scopus 로고    scopus 로고
    • Immunoablative therapy as a treatment aggressive multiple sclerosis
    • Atkins H, Freedman M. Immunoablative therapy as a treatment aggressive multiple sclerosis. Neurol Clin 2005; 23: 273-300.
    • (2005) Neurol Clin , vol.23 , pp. 273-300
    • Atkins, H.1    Freedman, M.2
  • 34
    • 33644812283 scopus 로고    scopus 로고
    • Randomised comparison of two B-cell purging protocols for patients with B-cell non-Hodgkin lymphoma: in vivo purging with rituximab versus ex vivo purging with CliniMACS CD34 cell enrichment device
    • van Heeckeren WJ, Vollweiler J, Fu P, et al. Randomised comparison of two B-cell purging protocols for patients with B-cell non-Hodgkin lymphoma: in vivo purging with rituximab versus ex vivo purging with CliniMACS CD34 cell enrichment device. Br J Haematol 2006; 132: 42-55.
    • (2006) Br J Haematol , vol.132 , pp. 42-55
    • van Heeckeren, W.J.1    Vollweiler, J.2    Fu, P.3
  • 35
    • 79960280145 scopus 로고    scopus 로고
    • In-vivo purging of the circulating clonal T-cells with Alemtuzumab prior to autologous peripheral blood hematopoietic cell mobilization and transplantation
    • Shustov A, Cherian S, Shaw A, et al. In-vivo purging of the circulating clonal T-cells with Alemtuzumab prior to autologous peripheral blood hematopoietic cell mobilization and transplantation. Br J Haematol 2011; 154: 415-418.
    • (2011) Br J Haematol , vol.154 , pp. 415-418
    • Shustov, A.1    Cherian, S.2    Shaw, A.3
  • 36
    • 0018842493 scopus 로고
    • Determination of cyclophosphamide in urine, serum and cerebrospinal fluid of multiple sclerosis patients by field desorption mass spectrometry
    • Bahr U, Schulten HR, Hommes OR, Aerts F. Determination of cyclophosphamide in urine, serum and cerebrospinal fluid of multiple sclerosis patients by field desorption mass spectrometry. Clin Chim Acta 1980; 103: 183-192.
    • (1980) Clin Chim Acta , vol.103 , pp. 183-192
    • Bahr, U.1    Schulten, H.R.2    Hommes, O.R.3    Aerts, F.4
  • 37
    • 0024311445 scopus 로고
    • Pharmacokinetic and metabolic studies of high-dose busulphan in adults
    • Hassan M, Oberg G, Ehrsson H, et al. Pharmacokinetic and metabolic studies of high-dose busulphan in adults. Eur J Clin Pharmacol 1989; 36: 525-530.
    • (1989) Eur J Clin Pharmacol , vol.36 , pp. 525-530
    • Hassan, M.1    Oberg, G.2    Ehrsson, H.3
  • 38
    • 12144289198 scopus 로고    scopus 로고
    • Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases
    • Nash RA, Dansey R, Storek J, et al. Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. Biol Blood Marrow Transplant 2003; 9: 583-591.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 583-591
    • Nash, R.A.1    Dansey, R.2    Storek, J.3
  • 39
    • 33745875004 scopus 로고    scopus 로고
    • Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis
    • Chen JT, Collins DL, Atkins HL, et al. Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis. Neurology 2006; 66: 1935-1937.
    • (2006) Neurology , vol.66 , pp. 1935-1937
    • Chen, J.T.1    Collins, D.L.2    Atkins, H.L.3
  • 41
    • 79959278762 scopus 로고    scopus 로고
    • Prospective neurocognitive function over 5 years after allogeneic hematopoietic cell transplantation for cancer survivors compared with matched controls at 5 years
    • Syrjala KL, Artherholt SB, Kurland BF, et al. Prospective neurocognitive function over 5 years after allogeneic hematopoietic cell transplantation for cancer survivors compared with matched controls at 5 years. J Clin Oncol 2011; 29: 2397-2404.
    • (2011) J Clin Oncol , vol.29 , pp. 2397-2404
    • Syrjala, K.L.1    Artherholt, S.B.2    Kurland, B.F.3
  • 42
    • 0034576841 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in multiple sclerosis with busulphan and cyclophosphamide conditioning: report of toxicity and immunological monitoring
    • Openshaw H, Lund BT, Kashyap A, et al. Peripheral blood stem cell transplantation in multiple sclerosis with busulphan and cyclophosphamide conditioning: report of toxicity and immunological monitoring. Biol Blood Marrow Transplant 2000; 6: 563-575.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 563-575
    • Openshaw, H.1    Lund, B.T.2    Kashyap, A.3
  • 43
    • 0032407103 scopus 로고    scopus 로고
    • Value of the pretransplant evaluation in predicting toxic day-100 mortality among blood stem-cell and bone marrow transplant recipients
    • Goldberg SL, Klumpp TR, Magdalinski AJ, Mangan KF. Value of the pretransplant evaluation in predicting toxic day-100 mortality among blood stem-cell and bone marrow transplant recipients. J Clin Oncol 1998; 16: 3796-3802.
    • (1998) J Clin Oncol , vol.16 , pp. 3796-3802
    • Goldberg, S.L.1    Klumpp, T.R.2    Magdalinski, A.J.3    Mangan, K.F.4
  • 44
    • 76749098044 scopus 로고    scopus 로고
    • Neurotoxicity of cancer treatment
    • Chamberlain MC. Neurotoxicity of cancer treatment. Curr Oncol Rep 2010; 12: 60-67.
    • (2010) Curr Oncol Rep , vol.12 , pp. 60-67
    • Chamberlain, M.C.1
  • 45
    • 79951548112 scopus 로고    scopus 로고
    • Autologous hematopoietic cell transplantation for multiple sclerosis: a systematic review
    • Reston JT, Uhl S, Treadwell JR, Nash RA, Schoelles K. Autologous hematopoietic cell transplantation for multiple sclerosis: a systematic review. Mult Scler 2011; 17: 204-213.
    • (2011) Mult Scler , vol.17 , pp. 204-213
    • Reston, J.T.1    Uhl, S.2    Treadwell, J.R.3    Nash, R.A.4    Schoelles, K.5
  • 46
    • 20144364694 scopus 로고    scopus 로고
    • Autologous stem cell transplantation as rescue therapy in malignant forms of multiple sclerosis
    • Mancardi GL, Murialdo A, Rossi P, et al. Autologous stem cell transplantation as rescue therapy in malignant forms of multiple sclerosis. Mult Scler 2005; 11: 367-371.
    • (2005) Mult Scler , vol.11 , pp. 367-371
    • Mancardi, G.L.1    Murialdo, A.2    Rossi, P.3
  • 47
    • 43149097417 scopus 로고    scopus 로고
    • Autologous stem-cell transplantation in malignant multiple sclerosis: a case with a favorable long-term outcome
    • Kimiskidis V, Sakellari I, Tsimourtou V, et al. Autologous stem-cell transplantation in malignant multiple sclerosis: a case with a favorable long-term outcome. Mult Scler 2008; 14: 278-283.
    • (2008) Mult Scler , vol.14 , pp. 278-283
    • Kimiskidis, V.1    Sakellari, I.2    Tsimourtou, V.3
  • 48
    • 59349089705 scopus 로고    scopus 로고
    • Early highly aggressive MS successfully treated by hematopoietic stem cell transplantation
    • Fagius J, Lundgren J, Oberg G. Early highly aggressive MS successfully treated by hematopoietic stem cell transplantation. Mult Scler 2009; 15: 229-237.
    • (2009) Mult Scler , vol.15 , pp. 229-237
    • Fagius, J.1    Lundgren, J.2    Oberg, G.3
  • 49
    • 60049083956 scopus 로고    scopus 로고
    • Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study
    • Burt RK, Loh Y, Cohen B, et al. Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study. Lancet Neurol 2009; 8: 244-253.
    • (2009) Lancet Neurol , vol.8 , pp. 244-253
    • Burt, R.K.1    Loh, Y.2    Cohen, B.3
  • 50
    • 77953735863 scopus 로고    scopus 로고
    • High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience
    • Krasulová E, Trneny M, Kozák T, et al. High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single centre 10-year experience. Mult Scler 2010; 16: 685-693.
    • (2010) Mult Scler , vol.16 , pp. 685-693
    • Krasulová, E.1    Trneny, M.2    Kozák, T.3
  • 51
    • 84861811380 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-centre experience
    • Mancardi GL, Sormani MP, Di Gioia M, et al. Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-centre experience. Mult Scler 2012; 18: 835-842.
    • (2012) Mult Scler , vol.18 , pp. 835-842
    • Mancardi, G.L.1    Sormani, M.P.2    Di Gioia, M.3
  • 52
    • 79953208669 scopus 로고    scopus 로고
    • Long-term results of stem cell transplantation for MS: a single-center experience
    • Fassas A, Kimiskidis VK, Sakellari I, et al. Long-term results of stem cell transplantation for MS: a single-center experience. Neurology 2011; 76: 1066-1070.
    • (2011) Neurology , vol.76 , pp. 1066-1070
    • Fassas, A.1    Kimiskidis, V.K.2    Sakellari, I.3
  • 53
    • 20144368500 scopus 로고    scopus 로고
    • Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life
    • Saccardi R, Mancardi GL, Solari A, et al. Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life. Blood 2005; 105: 2601-2607.
    • (2005) Blood , vol.105 , pp. 2601-2607
    • Saccardi, R.1    Mancardi, G.L.2    Solari, A.3
  • 54
    • 84863727030 scopus 로고    scopus 로고
    • Autologous hematopoietic cell transplantation following high-dose immunosuppressive therapy for advanced multiple sclerosis: long-term results
    • Bowen JD, Kraft GH, Wundes A, et al. Autologous hematopoietic cell transplantation following high-dose immunosuppressive therapy for advanced multiple sclerosis: long-term results. Bone Marrow Transplant 2012; 47: 946-951.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 946-951
    • Bowen, J.D.1    Kraft, G.H.2    Wundes, A.3
  • 55
    • 77954315037 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for multiple sclerosis: collaboration of the CIBMTR and EBMT to facilitate international clinical studies
    • Pasquini MC, Griffith LM, Arnold DL, et al. Hematopoietic stem cell transplantation for multiple sclerosis: collaboration of the CIBMTR and EBMT to facilitate international clinical studies. Biol Blood Marrow Transplant 2010; 16: 1076-1083.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1076-1083
    • Pasquini, M.C.1    Griffith, L.M.2    Arnold, D.L.3
  • 56
    • 84873113286 scopus 로고    scopus 로고
    • In: Center for International Blood and Marrow Transplant Research. Available at, Accessed August 5, 2012
    • Muraro P. Long-term outcomes after autologous HCT for severe multiple sclerosis. In: Center for International Blood and Marrow Transplant Research. Available at: www. cibmtr. org/Studies/Observational/StudyLists/pages/ObservationalStudy. aspx?OSID=34. Accessed August 5, 2012.
    • Long-term outcomes after autologous HCT for severe multiple sclerosis
    • Muraro, P.1
  • 57
    • 84861802589 scopus 로고    scopus 로고
    • A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper
    • Saccardi R, Freedman MS, Sormani MP, et al. A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper. Mult Scler 2012; 18: 825-834.
    • (2012) Mult Scler , vol.18 , pp. 825-834
    • Saccardi, R.1    Freedman, M.S.2    Sormani, M.P.3
  • 58
    • 84867405187 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation with reduced intensity conditioning in multiple sclerosis
    • Shevchenko JL, Kuznetsov AN, Ionova TI, et al. Autologous haematopoietic stem cell transplantation with reduced intensity conditioning in multiple sclerosis. Exp Hematol 2012; 40: 892-898.
    • (2012) Exp Hematol , vol.40 , pp. 892-898
    • Shevchenko, J.L.1    Kuznetsov, A.N.2    Ionova, T.I.3
  • 59
    • 84863984951 scopus 로고    scopus 로고
    • Long-term efficacy of autologous haematopoietic stem cell transplantation in multiple sclerosis at a single institution in China
    • Chen B, Zhou M, Ouyang J, et al. Long-term efficacy of autologous haematopoietic stem cell transplantation in multiple sclerosis at a single institution in China. Neurol Sci 2012; 33: 881-886.
    • (2012) Neurol Sci , vol.33 , pp. 881-886
    • Chen, B.1    Zhou, M.2    Ouyang, J.3
  • 60
    • 81255129068 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy: an unexpected complication of modern therapeutic monoclonal antibody therapies
    • Tavazzi E, Ferrante P, Khalili K. Progressive multifocal leukoencephalopathy: an unexpected complication of modern therapeutic monoclonal antibody therapies. Clin Microbiol Infect 2011; 17: 1776-1780.
    • (2011) Clin Microbiol Infect , vol.17 , pp. 1776-1780
    • Tavazzi, E.1    Ferrante, P.2    Khalili, K.3
  • 61
    • 84861022041 scopus 로고    scopus 로고
    • Risk of natalizumab-associated progressive multifocal leukoencephalopathy
    • Bloomgren G, Richman S, Hotermans C, et al. Risk of natalizumab-associated progressive multifocal leukoencephalopathy. N Engl J Med 2012; 366: 1870-1880.
    • (2012) N Engl J Med , vol.366 , pp. 1870-1880
    • Bloomgren, G.1    Richman, S.2    Hotermans, C.3
  • 62
    • 80051637474 scopus 로고    scopus 로고
    • Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party
    • Daikeler T, Labopin M, Di Gioia M, et al. Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party. Blood 2011; 118: 1693-1698.
    • (2011) Blood , vol.118 , pp. 1693-1698
    • Daikeler, T.1    Labopin, M.2    Di Gioia, M.3
  • 63
    • 33947271519 scopus 로고    scopus 로고
    • Development of a secondary autoimmune disorder after hematopoietic stem cell transplantation for autoimmune diseases: role of conditioning regimen used
    • Loh Y, Oyama Y, Statkute L, et al. Development of a secondary autoimmune disorder after hematopoietic stem cell transplantation for autoimmune diseases: role of conditioning regimen used. Blood 2007; 109: 2643-2548.
    • (2007) Blood , vol.109 , pp. 2548-2643
    • Loh, Y.1    Oyama, Y.2    Statkute, L.3
  • 64
    • 83455210452 scopus 로고    scopus 로고
    • A distinctive form of immune thrombocytopenia in a phase 2 study of alemtuzumab for the treatment of relapsing-remitting multiple sclerosis
    • Cuker A, Coles AJ, Sullivan H, et al. A distinctive form of immune thrombocytopenia in a phase 2 study of alemtuzumab for the treatment of relapsing-remitting multiple sclerosis. Blood 2011; 118: 6299-6305.
    • (2011) Blood , vol.118 , pp. 6299-6305
    • Cuker, A.1    Coles, A.J.2    Sullivan, H.3
  • 65
    • 77954863353 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation for secondary progressive multiple sclerosis: an exploratory cost-effectiveness analysis
    • Tappenden P, Saccardi R, Confavreux C, et al. Autologous haematopoietic stem cell transplantation for secondary progressive multiple sclerosis: an exploratory cost-effectiveness analysis. Bone Marrow Transplant 2010; 45: 1014-1021.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1014-1021
    • Tappenden, P.1    Saccardi, R.2    Confavreux, C.3
  • 66
    • 80052767484 scopus 로고    scopus 로고
    • Cost-effectiveness of natalizumab versus fingolimod for the treatment of relapsing multiple sclerosis
    • O'Day K, Meyer K, Miller RM, Agarwal S, Franklin M. Cost-effectiveness of natalizumab versus fingolimod for the treatment of relapsing multiple sclerosis. J Med Econ 2011; 14: 617-627.
    • (2011) J Med Econ , vol.14 , pp. 617-627
    • O'Day, K.1    Meyer, K.2    Miller, R.M.3    Agarwal, S.4    Franklin, M.5
  • 67
    • 70349878541 scopus 로고    scopus 로고
    • Comparing the cost-effectiveness of disease-modifying drugs for the first-line treatment of relapsing-remitting multiple sclerosis
    • Goldberg LD, Edwards NC, Fincher C, Doan QV, Al-Sabbagh A, Meletiche DM. Comparing the cost-effectiveness of disease-modifying drugs for the first-line treatment of relapsing-remitting multiple sclerosis. J Manag Care Pharm 2009; 15: 543-555.
    • (2009) J Manag Care Pharm , vol.15 , pp. 543-555
    • Goldberg, L.D.1    Edwards, N.C.2    Fincher, C.3    Doan, Q.V.4    Al-Sabbagh, A.5    Meletiche, D.M.6
  • 68
    • 84869830323 scopus 로고    scopus 로고
    • Cost-effectiveness of fingolimod versus interferon beta-1a for relapsing remitting multiple sclerosis in the United States
    • Lee S, Baxter DC, Limone B, Roberts MS, Coleman CI. Cost-effectiveness of fingolimod versus interferon beta-1a for relapsing remitting multiple sclerosis in the United States. J Med Econ 2012; 15: 1088-1096.
    • (2012) J Med Econ , vol.15 , pp. 1088-1096
    • Lee, S.1    Baxter, D.C.2    Limone, B.3    Roberts, M.S.4    Coleman, C.I.5
  • 69
    • 79959385154 scopus 로고    scopus 로고
    • Cost-effectiveness of disease-modifying therapy for multiple sclerosis: a population-based study
    • Noyes K, Bajorska A, Chappel A, et al. Cost-effectiveness of disease-modifying therapy for multiple sclerosis: a population-based study. Neurology 2011; 77: 355-363.
    • (2011) Neurology , vol.77 , pp. 355-363
    • Noyes, K.1    Bajorska, A.2    Chappel, A.3
  • 70
    • 78650838800 scopus 로고    scopus 로고
    • A preliminary result of treatment of neuromyelitis optica with autologous peripheral hematopoietic stem cell transplantation
    • Peng F, Qiu W, Li J, et al. A preliminary result of treatment of neuromyelitis optica with autologous peripheral hematopoietic stem cell transplantation. Neurologist 2010; 16: 375-378.
    • (2010) Neurologist , vol.16 , pp. 375-378
    • Peng, F.1    Qiu, W.2    Li, J.3
  • 71
    • 79951683336 scopus 로고    scopus 로고
    • Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population
    • Xu J, Ji BX, Su L, et al. Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population. Ann Hematol 2011; 90: 343-348.
    • (2011) Ann Hematol , vol.90 , pp. 343-348
    • Xu, J.1    Ji, B.X.2    Su, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.