Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties

Journal of Molecular and Cellular Cardiology

Volumn 56, Issue 1, 2013, Pages 44-54

  Jeong, Euy Myoung ^a   Monasky, Michelle M ^a   Gu, Lianzhi ^a   Taglieri, Domenico M ^a   Patel, Bindiya G ^a   Liu, Hong ^a   Wang, Qiongying ^a   Greener, Ian ^a   Dudley, Samuel C ^a   Solaro, R John ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Ca2+ sensitivity; Deoxycorticosterone acetate (DOCA) salt mice; Diastolic heart failure; MyBP C; Oxidative stress; S glutathionylation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CELL PROTEIN; DEOXYCORTICOSTERONE ACETATE; MYOFILAMENT PROTEIN; MYOSIN BINDING PROTEIN C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SARCOMERIC PROTEIN; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPLETION; DIASTOLIC DYSFUNCTION; DIET SUPPLEMENTATION; DRUG MECHANISM; ENZYME ACTIVITY; HEART LEFT VENTRICLE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HYPERTENSION; IMMUNOBLOTTING; MOUSE; MUSCLE STRENGTH; MUSCLE TONE; MYOFILAMENT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; S GLUTATHIONYLATION; SARCOMERE LENGTH; TRANSTHORACIC ECHOCARDIOGRAPHY; TREATMENT DURATION;

ADENOSINE TRIPHOSPHATASES; ADMINISTRATION, ORAL; ANIMALS; BIOPTERIN; CARDIOVASCULAR AGENTS; CARRIER PROTEINS; CELLS, CULTURED; DESOXYCORTICOSTERONE; DIASTOLE; DIETARY SUPPLEMENTS; GLUTATHIONE; HEART FAILURE, DIASTOLIC; MICE; MYOFIBRILS; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; STROKE VOLUME;

MUS;

EID: 84873140248     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.12.003     Document Type: Article

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