-
1
-
-
81555216735
-
British guidelines on the management of asthma british guidelines on the management of asthma: What's new for 2011?
-
Turner S, Paton J, Higgins B, Douglas G; British Guidelines on the Management of Asthma. British guidelines on the management of asthma: what's new for 2011? Thorax 66(12), 1104-1105 (2011).
-
(2011)
Thorax
, vol.66
, pp. 1104-1105
-
-
Turner, S.1
Paton, J.2
Higgins, B.3
Douglas, G.4
-
2
-
-
15844363866
-
Severe asthma treatment: Need for characterising patients
-
DOI 10.1016/S0140-6736(05)71087-4, PII S0140673605710874
-
Heaney LG, Robinson DS. Severe asthma treatment: need for characterising patients. Lancet 365(9463), 974-976 (2005). (Pubitemid 41071432)
-
(2005)
Lancet
, vol.365
, Issue.9463
, pp. 974-976
-
-
Heaney, L.G.1
Robinson, D.S.2
-
3
-
-
10744224453
-
Asthma and Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma
-
Robinson DS, Campbell DA, Durham SR, Pfeffer J, Barnes PJ, Chung KF; Asthma and Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma. Eur. Respir. J. 22(3), 478-483 (2003).
-
(2003)
Eur. Respir. J
, vol.22
, Issue.3
, pp. 478-483
-
-
Robinson, D.S.1
Campbell, D.A.2
Durham, S.R.3
Pfeffer, J.4
Barnes, P.J.5
Chung, K.F.6
-
4
-
-
70350458755
-
The prevalence of nonadherence in difficult asthma
-
Gamble J, Stevenson M, McClean E, Heaney LG. The prevalence of nonadherence in difficult asthma. Am. J. Respir. Crit. Care Med. 180(9), 817-822 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med
, vol.180
, Issue.9
, pp. 817-822
-
-
Gamble, J.1
Stevenson, M.2
McClean, E.3
Heaney, L.G.4
-
6
-
-
76149146032
-
Severe asthma research program. Identification of asthma phenotypes using cluster analysis in the severe asthma research program
-
National Heart, Lung, and Blood Institute'
-
Moore WC, Meyers DA, Wenzel SE et al.; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am. J. Respir. Crit. Care Med. 181(4), 315-323 (2010).
-
(2010)
Am. J. Respir. Crit. Care Med
, vol.181
, Issue.4
, pp. 315-323
-
-
Moore, W.C.1
Meyers, D.A.2
Wenzel, S.E.3
-
7
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, Modrek B, Choy DF et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am. J. Respir. Crit. Care Med. 180(5), 388-395 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med
, vol.180
, Issue.5
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
-
8
-
-
78649868199
-
The role of the T cell in asthma
-
quiz 1092
-
Robinson DS. The role of the T cell in asthma. J. Allergy Clin. Immunol. 126(6), 1081-1091; quiz 1092 (2010).
-
(2010)
J. Allergy Clin. Immunol
, vol.126
, Issue.6
, pp. 1081-1091
-
-
Robinson, D.S.1
-
9
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
-
DOI 10.1016/S0140-6736(02)11679-5
-
Green RH, Brightling CE, McKenna S et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 360(9347), 1715-1721 (2002). (Pubitemid 35447900)
-
(2002)
Lancet
, vol.360
, Issue.9347
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
Hargadon, B.4
Parker, D.5
Bradding, P.6
Wardlaw, A.J.7
Pavord, I.D.8
-
10
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie MJ, ten Brinke A, Khan J et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356(9248), 2144-2148 (2000).
-
(2000)
Lancet
, vol.356
, Issue.9248
, pp. 2144-2148
-
-
Leckie, M.J.1
Ten Brinke, A.2
Khan, J.3
-
11
-
-
0037438409
-
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
-
DOI 10.1164/rccm.200208-789OC
-
Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am. J. Respir. Crit. Care Med. 167(2), 199-204 (2003). (Pubitemid 36076080)
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.167
, Issue.2
, pp. 199-204
-
-
Flood-Page, P.T.1
Menzies-Gow, A.N.2
Kay, A.B.3
Robinson, D.S.4
-
12
-
-
36749065556
-
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
-
DOI 10.1164/rccm.200701-085OC
-
Flood-Page P, Swenson C, Faiferman I et al.; International mepolizumab Study Group. A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am. J. Respir. Crit. Care Med. 176(11), 1062-1071 (2007). (Pubitemid 350223751)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.176
, Issue.11
, pp. 1062-1071
-
-
Flood-Page, P.1
Swenson, C.2
Faiferman, I.3
Matthews, J.4
Williams, M.5
Brannick, L.6
Robinson, D.7
Wenzel, S.8
Busse, W.9
Hansel, T.T.10
Barnes, N.C.11
-
13
-
-
81455155725
-
Res-5-0010 Study Group. Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
-
Castro M, Mathur S, Hargreave F et al.; Res-5-0010 Study Group. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am. J. Respir. Crit. Care Med. 184(10), 1125-1132 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med
, vol.184
, Issue.10
, pp. 1125-1132
-
-
Castro, M.1
Mathur, S.2
Hargreave, F.3
-
14
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N. Engl. J. Med. 360(10), 973-984 (2009).
-
(2009)
N. Engl. J. Med
, vol.360
, Issue.10
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
-
15
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N. Engl. J. Med. 360(10), 985-993 (2009).
-
(2009)
N. Engl. J. Med
, vol.360
, Issue.10
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
-
16
-
-
84872201308
-
Mepolizumab treatment for asthma
-
Robinson DS. Mepolizumab treatment for asthma. Expert Opin. Biol. Ther. 13(2), 295-302 (2013).
-
Expert Opin. Biol. Ther
, vol.13
, Issue.2
, pp. 295-302
-
-
Robinson, D.S.1
-
17
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 380(9842), 651-659 (2012).
-
(2012)
Lancet 380
, vol.9842
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
-
18
-
-
85047693849
-
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
-
DOI 10.1172/JCI200317974
-
Flood-Page P, Menzies-Gow A, Phipps S et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J. Clin. Invest. 112(7), 1029-1036 (2003). (Pubitemid 38056318)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.7
, pp. 1029-1036
-
-
Flood-Page, P.1
Menzies-Gow, A.2
Phipps, S.3
Ying, S.4
Wangoo, A.5
Ludwig, M.S.6
Barnes, N.7
Robinson, D.8
Kay, A.B.9
-
19
-
-
33750511120
-
Airway inflammation assessed by invasive and noninvasive means in severe asthma: Eosinophilic and noneosinophilic phenotypes
-
DOI 10.1016/j.jaci.2006.08.003, PII S0091674906017027
-
Lemière C, Ernst P, Olivenstein R et al. Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J. Allergy Clin. Immunol. 118(5), 1033-1039 (2006). (Pubitemid 44666987)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.118
, Issue.5
, pp. 1033-1039
-
-
Lemiere, C.1
Ernst, P.2
Olivenstein, R.3
Yamauchi, Y.4
Govindaraju, K.5
Ludwig, M.S.6
Martin, J.G.7
Hamid, Q.8
-
20
-
-
70350312668
-
Inflammatory biomarkers in airways ofpatients with severe asthma compared with non-severe asthma
-
Macedo P, Hew M, Torrego A et al. Inflammatory biomarkers in airways ofpatients with severe asthma compared with non-severe asthma. Clin. Exp. Allergy 39(11), 1668-1676 (2009).
-
(2009)
Clin. Exp. Allergy
, vol.39
, Issue.11
, pp. 1668-1676
-
-
MacEdo, P.1
Hew, M.2
Torrego, A.3
-
22
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF, Hanania NA et al. Lebrikizumab treatment in adults with asthma. N. Engl. J. Med. 365(12), 1088-1098 (2011).
-
(2011)
N. Engl. J. Med
, vol.365
, Issue.12
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
-
23
-
-
81255157071
-
Omalizumab in the treatment of asthma
-
Tan R, Corren J. Omalizumab in the treatment of asthma. Expert Rev. Respir. Med. 5(6), 747-756 (2011).
-
(2011)
Expert Rev. Respir. Med
, vol.5
, Issue.6
, pp. 747-756
-
-
Tan, R.1
Corren, J.2
-
24
-
-
74949090750
-
AIR2 Trial Study Group. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized, double-blind, sham-controlled clinical trial
-
Castro M, Rubin AS, Laviolette M et al.; AIR2 Trial Study Group. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am. J. Respir. Crit. Care Med. 181(2), 116-124 (2010).
-
(2010)
Am. J. Respir. Crit. Care Med
, vol.181
, Issue.2
, pp. 116-124
-
-
Castro, M.1
Rubin, A.S.2
Laviolette, M.3
-
25
-
-
80052829963
-
-
Unbiased Biomarkers For The Prediction Of Respiratory Disease Outcome (U-BIOPRED) Consortium Consensus Generation. Diagnosis And Definition Of Severe Refractory Asthma: An International Consensus Statement From The Innovative Medicine Initiative (IMI)
-
Bel EH, Sousa A, Fleming L et al.; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome (U-BIOPRED) Consortium, Consensus Generation. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax 66(10), 910-917 (2011).
-
(2011)
Thorax
, vol.66
, Issue.10
, pp. 910-917
-
-
Bel, E.H.1
Sousa, A.2
Fleming, L.3
-
26
-
-
84864003908
-
Clinical management and outcome of refractory asthma in the uk from the british thoracic society difficult asthma registry
-
British Thoracic Society Difficult Asthma Network
-
Sweeney J, Brightling CE, Menzies-Gow A, Niven R, Patterson CC, Heaney LG; British Thoracic Society Difficult Asthma Network. Clinical management and outcome of refractory asthma in the UK from the British Thoracic Society Difficult Asthma Registry. Thorax 67(8), 754-756 (2012).
-
(2012)
Thorax
, vol.67
, Issue.8
, pp. 754-756
-
-
Sweeney, J.1
Brightling, C.E.2
Menzies-Gow, A.3
Niven, R.4
Patterson, C.C.5
Heaney, L.G.6
-
27
-
-
77952683218
-
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase i study of subjects with mild asthma
-
Busse WW, Katial R, Gossage D et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase I study of subjects with mild asthma. J. Allergy Clin. Immunol. 125(6), 1237-1244.e2 (2010).
-
(2010)
J. Allergy Clin. Immunol
, vol.125
, Issue.6
, pp. 1237-1244
-
-
Busse, W.W.1
Katial, R.2
Gossage, D.3
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