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Volumn 7, Issue 1, 2013, Pages 13-17

Mepolizumab for severe eosinophilic asthma

Author keywords

asthma; eosinophil; mepolizumab; severe asthma

Indexed keywords

MEPOLIZUMAB; NITRIC OXIDE;

EID: 84873120214     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.12.84     Document Type: Note
Times cited : (19)

References (29)
  • 1
    • 81555216735 scopus 로고    scopus 로고
    • British guidelines on the management of asthma british guidelines on the management of asthma: What's new for 2011?
    • Turner S, Paton J, Higgins B, Douglas G; British Guidelines on the Management of Asthma. British guidelines on the management of asthma: what's new for 2011? Thorax 66(12), 1104-1105 (2011).
    • (2011) Thorax , vol.66 , pp. 1104-1105
    • Turner, S.1    Paton, J.2    Higgins, B.3    Douglas, G.4
  • 2
    • 15844363866 scopus 로고    scopus 로고
    • Severe asthma treatment: Need for characterising patients
    • DOI 10.1016/S0140-6736(05)71087-4, PII S0140673605710874
    • Heaney LG, Robinson DS. Severe asthma treatment: need for characterising patients. Lancet 365(9463), 974-976 (2005). (Pubitemid 41071432)
    • (2005) Lancet , vol.365 , Issue.9463 , pp. 974-976
    • Heaney, L.G.1    Robinson, D.S.2
  • 3
    • 10744224453 scopus 로고    scopus 로고
    • Asthma and Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma
    • Robinson DS, Campbell DA, Durham SR, Pfeffer J, Barnes PJ, Chung KF; Asthma and Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma. Eur. Respir. J. 22(3), 478-483 (2003).
    • (2003) Eur. Respir. J , vol.22 , Issue.3 , pp. 478-483
    • Robinson, D.S.1    Campbell, D.A.2    Durham, S.R.3    Pfeffer, J.4    Barnes, P.J.5    Chung, K.F.6
  • 6
    • 76149146032 scopus 로고    scopus 로고
    • Severe asthma research program. Identification of asthma phenotypes using cluster analysis in the severe asthma research program
    • National Heart, Lung, and Blood Institute'
    • Moore WC, Meyers DA, Wenzel SE et al.; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am. J. Respir. Crit. Care Med. 181(4), 315-323 (2010).
    • (2010) Am. J. Respir. Crit. Care Med , vol.181 , Issue.4 , pp. 315-323
    • Moore, W.C.1    Meyers, D.A.2    Wenzel, S.E.3
  • 7
    • 69249150516 scopus 로고    scopus 로고
    • T-helper type 2-driven inflammation defines major subphenotypes of asthma
    • Woodruff PG, Modrek B, Choy DF et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am. J. Respir. Crit. Care Med. 180(5), 388-395 (2009).
    • (2009) Am. J. Respir. Crit. Care Med , vol.180 , Issue.5 , pp. 388-395
    • Woodruff, P.G.1    Modrek, B.2    Choy, D.F.3
  • 8
    • 78649868199 scopus 로고    scopus 로고
    • The role of the T cell in asthma
    • quiz 1092
    • Robinson DS. The role of the T cell in asthma. J. Allergy Clin. Immunol. 126(6), 1081-1091; quiz 1092 (2010).
    • (2010) J. Allergy Clin. Immunol , vol.126 , Issue.6 , pp. 1081-1091
    • Robinson, D.S.1
  • 10
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Leckie MJ, ten Brinke A, Khan J et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356(9248), 2144-2148 (2000).
    • (2000) Lancet , vol.356 , Issue.9248 , pp. 2144-2148
    • Leckie, M.J.1    Ten Brinke, A.2    Khan, J.3
  • 13
    • 81455155725 scopus 로고    scopus 로고
    • Res-5-0010 Study Group. Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
    • Castro M, Mathur S, Hargreave F et al.; Res-5-0010 Study Group. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am. J. Respir. Crit. Care Med. 184(10), 1125-1132 (2011).
    • (2011) Am. J. Respir. Crit. Care Med , vol.184 , Issue.10 , pp. 1125-1132
    • Castro, M.1    Mathur, S.2    Hargreave, F.3
  • 14
    • 61849086181 scopus 로고    scopus 로고
    • Mepolizumab and exacerbations of refractory eosinophilic asthma
    • Haldar P, Brightling CE, Hargadon B et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N. Engl. J. Med. 360(10), 973-984 (2009).
    • (2009) N. Engl. J. Med , vol.360 , Issue.10 , pp. 973-984
    • Haldar, P.1    Brightling, C.E.2    Hargadon, B.3
  • 15
    • 61849155730 scopus 로고    scopus 로고
    • Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
    • Nair P, Pizzichini MM, Kjarsgaard M et al. Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N. Engl. J. Med. 360(10), 985-993 (2009).
    • (2009) N. Engl. J. Med , vol.360 , Issue.10 , pp. 985-993
    • Nair, P.1    Pizzichini, M.M.2    Kjarsgaard, M.3
  • 16
    • 84872201308 scopus 로고    scopus 로고
    • Mepolizumab treatment for asthma
    • Robinson DS. Mepolizumab treatment for asthma. Expert Opin. Biol. Ther. 13(2), 295-302 (2013).
    • Expert Opin. Biol. Ther , vol.13 , Issue.2 , pp. 295-302
    • Robinson, D.S.1
  • 17
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 380(9842), 651-659 (2012).
    • (2012) Lancet 380 , vol.9842 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3
  • 20
    • 70350312668 scopus 로고    scopus 로고
    • Inflammatory biomarkers in airways ofpatients with severe asthma compared with non-severe asthma
    • Macedo P, Hew M, Torrego A et al. Inflammatory biomarkers in airways ofpatients with severe asthma compared with non-severe asthma. Clin. Exp. Allergy 39(11), 1668-1676 (2009).
    • (2009) Clin. Exp. Allergy , vol.39 , Issue.11 , pp. 1668-1676
    • MacEdo, P.1    Hew, M.2    Torrego, A.3
  • 22
    • 80053084755 scopus 로고    scopus 로고
    • Lebrikizumab treatment in adults with asthma
    • Corren J, Lemanske RF, Hanania NA et al. Lebrikizumab treatment in adults with asthma. N. Engl. J. Med. 365(12), 1088-1098 (2011).
    • (2011) N. Engl. J. Med , vol.365 , Issue.12 , pp. 1088-1098
    • Corren, J.1    Lemanske, R.F.2    Hanania, N.A.3
  • 23
    • 81255157071 scopus 로고    scopus 로고
    • Omalizumab in the treatment of asthma
    • Tan R, Corren J. Omalizumab in the treatment of asthma. Expert Rev. Respir. Med. 5(6), 747-756 (2011).
    • (2011) Expert Rev. Respir. Med , vol.5 , Issue.6 , pp. 747-756
    • Tan, R.1    Corren, J.2
  • 24
    • 74949090750 scopus 로고    scopus 로고
    • AIR2 Trial Study Group. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized, double-blind, sham-controlled clinical trial
    • Castro M, Rubin AS, Laviolette M et al.; AIR2 Trial Study Group. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am. J. Respir. Crit. Care Med. 181(2), 116-124 (2010).
    • (2010) Am. J. Respir. Crit. Care Med , vol.181 , Issue.2 , pp. 116-124
    • Castro, M.1    Rubin, A.S.2    Laviolette, M.3
  • 25
    • 80052829963 scopus 로고    scopus 로고
    • Unbiased Biomarkers For The Prediction Of Respiratory Disease Outcome (U-BIOPRED) Consortium Consensus Generation. Diagnosis And Definition Of Severe Refractory Asthma: An International Consensus Statement From The Innovative Medicine Initiative (IMI)
    • Bel EH, Sousa A, Fleming L et al.; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome (U-BIOPRED) Consortium, Consensus Generation. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax 66(10), 910-917 (2011).
    • (2011) Thorax , vol.66 , Issue.10 , pp. 910-917
    • Bel, E.H.1    Sousa, A.2    Fleming, L.3
  • 26
    • 84864003908 scopus 로고    scopus 로고
    • Clinical management and outcome of refractory asthma in the uk from the british thoracic society difficult asthma registry
    • British Thoracic Society Difficult Asthma Network
    • Sweeney J, Brightling CE, Menzies-Gow A, Niven R, Patterson CC, Heaney LG; British Thoracic Society Difficult Asthma Network. Clinical management and outcome of refractory asthma in the UK from the British Thoracic Society Difficult Asthma Registry. Thorax 67(8), 754-756 (2012).
    • (2012) Thorax , vol.67 , Issue.8 , pp. 754-756
    • Sweeney, J.1    Brightling, C.E.2    Menzies-Gow, A.3    Niven, R.4    Patterson, C.C.5    Heaney, L.G.6
  • 27
    • 77952683218 scopus 로고    scopus 로고
    • Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase i study of subjects with mild asthma
    • Busse WW, Katial R, Gossage D et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase I study of subjects with mild asthma. J. Allergy Clin. Immunol. 125(6), 1237-1244.e2 (2010).
    • (2010) J. Allergy Clin. Immunol , vol.125 , Issue.6 , pp. 1237-1244
    • Busse, W.W.1    Katial, R.2    Gossage, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.