A retrospective: Use of Escherichia coli as a vehicle to study phospholipid synthesis and function

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 3, 2013, Pages 471-494

  Dowhan, William ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Cardiolipin; Escherichia coli; Genetics; Membrane protein; Phosphatidylethanolamine; Phosphatidylglycerol

Indexed keywords

CARDIOLIPIN; CYTIDINE; PHOSPHATIDIC ACID; PHOSPHATIDYLSERINE DECARBOXYLASE; PHOSPHATIDYLSERINE SYNTHASE; PHOSPHOLIPID;

BACTERIAL STRAIN; CELL VIABILITY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE SEQUENCE; LIPID COMPOSITION; METABOLIC REGULATION; MOLECULAR GENETICS; NONHUMAN; PHOSPHOLIPID METABOLISM; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RETROSPECTIVE STUDY; REVIEW;

ANIMALS; BACTERIAL PROTEINS; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; MEMBRANE MICRODOMAINS; METABOLIC ENGINEERING; MUTATION; PHOSPHOLIPIDS; SEQUENCE ANALYSIS, DNA; STAINING AND LABELING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; MAMMALIA; PROKARYOTA;

EID: 84873100800     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.08.007     Document Type: Review

References (248)

1. Y. Koga, and H. Morii Biosynthesis of ether-type polar lipids in Archaea and evolutionary considerations Microbiol. Mol. Biol. Rev. 71 2007 97 120
2. A. Chibnall, and H. Channon The ether-soluble substances of cabbage leaf cytoplasm: calcium salts of glyceridephosphoric acids Biochem. J. 21 1927 233 246
3. A. Chibnall, and H. Channon The ether-soluble substances of cabbage leaf cytoplasm: preparation and general characters Biochem. J. 21 1927 225 232
4. P.A. Levene, and C.J. West Lecithin. I: "hydrolecithin" and its bearing on the constitution of cephalin J. Biol. Chem. 33 1918 111 117
5. P.A. Levene, C.J. West, and V. Cephalin Hydrocephalin of the egg yolk J. Biol. Chem. 35 1918 285 290
6. O. Chievitz, and G. Hevesy The first radioindicator study in the life sciences with a man-made radionuclide Nature 136 1935 1106 1107
7. R.G. Sinclair The metabolism of the phospholipids: VIII. The passage of elaidic acid into tissue phospholipids. Evidence of the intermediary role of liver phospholipid in fat metabolism J. Biol. Chem. 111 1935 515 526
8. C. Artom, G. Sarzana, C. Perrier, M. Santangelo, and E. Segre Rate of organification of phosphorus in animal tissue Nature 139 1937 836 837
9. I. Perlman, S. Ruben, and I.L. Chaikoff Radioactive phosphorus as an indicator of phospholipid metabolism. I. The rate of formation and destruction of phospholipids in the fasting rat J. Biol. Chem. 122 1937-38 169 182
10. M.A. Swanson, and C. Artom The lipid composition of the large granules (mitochondria) from rat liver J. Biol. Chem. 187 1950 281 287
11. A. Kornberg, and W.E. Pricer Jr. Enzymatic esterification of α-glycerophosphate by long chain fatty acids J. Biol. Chem. 204 1953 345 357
12. E.P. Kennedy Synthesis of phosphatides in isolated mitochondria J. Biol. Chem. 201 1953 399 412
13. A. Kornberg, and W.E. Pricer Jr. Fed. Proc. 11 1952 242
14. E.P. Kennedy Synthesis of phosphatides in isolated mitochondria. II. Incorporation of choline into lecithin J. Biol. Chem. 209 1954 525 535
15. E.P. Kennedy, and S.B. Weiss The function of cytidine coenzymes in the biosynthesis of phospholipids J. Biol. Chem. 222 1956 193 214
16. E.P. Kennedy Sailing to Byzantium Annu. Rev. Biochem. 61 1992 1 28
17. C.E. Castuma, E. Crooke, and A. Kornberg Fluid membranes with acidic domains activate DnaA, the initiator protein of replication in Escherichia coli J. Biol. Chem. 268 1993 24665 24668
18. K. Sekimizu, and A. Kornberg Cardiolipin activation of DnaA protein, the initiation protein of replication in Escherichia coli J. Biol. Chem. 263 1988 7131 7135
19. M. Rodbell, and D.J. Hanahan Lecithin synthesis in liver J. Biol. Chem. 214 1954 607 618
20. B.W. Agranoff, R.M. Bradley, and R.O. Brady The enzymatic synthesis of inositol phosphatide J. Biol. Chem. 233 1958 1077 1083
21. H. Paulus, and E.P. Kennedy The enzymatic synthesis of inositol monophosphatide J. Biol. Chem. 235 1960 1303 1311
22. M. Colodzin, and E.P. Kennedy Biosynthesis of diphosphoinositide in brain J. Biol. Chem. 240 1965 3771 3780
23. D.R. Voelker, and E.P. Kennedy Cellular and enzymic synthesis of sphingomyelin Biochemistry 21 1982 2753 2759
24. R.M. Bell Mutants of Escherichia coli defective in membrane phospholipid synthesis: macromolecular synthesis in an sn-glycerol 3-phosphate acyltransferase Km mutant J. Bacteriol. 117 1974 1065 1076
25. J. Coleman Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3- phosphate acyltransferase activity J. Biol. Chem. 265 1990 17215 17221
26. J. Yao, and C.O. Rock Phosphatidic Acid Synthesis in Bacteria Biochim. Biophys. Acta 1831 2013 495 502
27. R. Matsumi, H. Atomi, A.J. Driessen, and J. van der Oost Isoprenoid biosynthesis in Archaea-biochemical and evolutionary implications Res. Microbiol. 162 2011 39 52
28. S.A. Henry, S.D. Kohlwein, and G.M. Carman Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae Genetics 190 2012 317 349
29. E.R. Moellering, and C. Benning Galactoglycerolipid metabolism under stress: a time for remodeling Trends Plant Sci. 16 2011 98 107
30. Z. Li, and D.E. Vance Phosphatidylcholine and choline homeostasis J. Lipid Res. 49 2008 1187 1194
31. M. Hermansson, K. Hokynar, and P. Somerharju Mechanisms of glycerophospholipid homeostasis in mammalian cells Prog. Lipid Res. 50 2011 240 257
32. J. Kanfer, and E.P. Kennedy Metabolism and function of bacterial lipids. I. Metabolism of phospholipids in Escherichia coli B J. Biol. Chem. 238 1963 2919 2922
33. S. Jackowski, and C.O. Rock Transfer of fatty acids from the 1-position of phosphatidylethanolamine to the major outer membrane lipoprotein of Escherichia coli J. Biol. Chem. 261 1986 11328 11333
34. C.O. Rock Turnover of fatty acids in the 1-position of phosphatidylethanolamine in Escherichia coli J. Biol. Chem. 259 1984 6188 6194
35. S. Jackowski, P.D. Jackson, and C.O. Rock Sequence and function of the aas gene in Escherichia coli J. Biol. Chem. 269 1994 2921 2928
36. J. Kanfer, and E.P. Kennedy Metabolism and function of bacterial lipids. II. Biosynthesis of phospholipids in Escherichia Coli J. Biol. Chem. 239 1964 1720 1726
37. J.N. Kanfer, and E.P. Kennedy Synthesis of phosphatidylserine by Escherichia coli J. Biol. Chem. 237 1962 PC270 PC271
38. L.F. Borkenhagen, E.P. Kennedy, and L. Fielding Enzymatic formation and decarboxylation of phosphatidylserine J. Biol. Chem. 236 1961 PC28 PC30
39. G. Hübscher, R.R. Dils, and W.F. Pover Studies on the biosynthesis of phosphatidyl serine Biochim. Biophys. Acta 36 1959 518 528
40. E. Delhaize, D.M. Hebb, K.D. Richards, J.M. Lin, P.R. Ryan, and R.C. Gardner Cloning and expression of a wheat (Triticum aestivum L.) phosphatidylserine synthase cDNA. Overexpression in plants alters the composition of phospholipids J. Biol. Chem. 274 1999 7082 7088
41. J.Y. Kiyasu, R.A. Pieringer, H. Paulus, and E.P. Kennedy The biosynthesis of phosphatidylglycerol J. Biol. Chem. 238 1963 2293 2298
42. Y.Y. Chang, and E.P. Kennedy Phosphatidyl glycerophosphate phosphatase J. Lipid Res. 8 1967 456 462
43. Y.H. Lu, Z. Guan, J. Zhao, and C.R. Raetz Three phosphatidylglycerol- phosphate phosphatases in the inner membrane of Escherichia coli J. Biol. Chem. 286 2011 5506 5518
44. J.R. Carter Jr. Cytidine triphosphate: phosphatidic acid cytidyltransferase in Escherichia coli J. Lipid Res. 9 1968 748 754
45. M.C. Pangborn Isolation and purification of a serologically active phospholipid from beef heart J. Biol. Chem. 142 1942 247 256
46. M.G. Macfarlane Structure of cardiolipin Nature 182 1958 946
47. N.Z. Stanacev, Y.Y. Chang, and E.P. Kennedy Biosynthesis of cardiolipin in Escherichia coli J. Biol. Chem. 242 1967 3018 3019
48. K.Y. Hostetler, H. van den Bosch, and L.L. van Deenen The mechanism of cardiolipin biosynthesis in liver mitochondria Biochim. Biophys. Acta 260 1972 507 513
49. C.B. Hirschberg, and E.P. Kennedy Mechanism of the enzymatic synthesis of cardiolipin in Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 69 1972 648 651
50. B.K. Tan, M. Bogdanov, J. Zhao, W. Dowhan, C.R.H. Raetz, and Z. Guan Discovery of a novel cardiolipin synthase in Escherichia coli utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates Proc. Natl. Acad. Sci. U. S. A. 2012 (in press)
51. K. Okonogi, I. Shibuya, and B. Maruo Isolation of Escherichia coli mutants with temperature sensitive synthesis of phosphatidylethanolamine Seikagaku 43 1971 665 (in Japanese)
52. A. Ohta, K. Okonogi, I. Shibuya, and B. Maruo Isolation of Escherichia coli mutants with temperature-sensitive formation of phosphatidylethanolamine J. Gen. Appl. Microbiol. 20 1974 21 32
53. A. Ohta, and I. Shibuya Membrane phospholipid synthesis and phenotypic correlation of an Escherichia coli pss mutant J. Bacteriol. 132 1977 434 443
54. A. Ohta, I. Shibuya, and B. Maruo Escherichia coli mutants with temperature-sensitive phosphatidylserine synthetase: genetic analysis Agric. Biol. Chem. 39 1975 2443 2445
55. A. Ohta, I. Shibuya, B. Maruo, M. Ishinaga, and M. Kito An extremely labile phosphatidylserine synthetase of an Escherichia coli mutant with the temperature-sensitive formation of phosphatidylethanolamine Biochim. Biophys. Acta 348 1974 449 454
56. R.M. Bell Mutants of Escherichia coli defective in membrane phospholipid synthesis. Properties of wild type and Km defective sn-glycerol-3-phosphate acyltransferase activities J. Biol. Chem. 250 1975 7147 7152
57. C.R. Raetz Isolation of Escherichia coli mutants defective in enzymes of membrane lipid synthesis Proc. Natl. Acad. Sci. U. S. A. 72 1975 2274 2278
58. C.R. Raetz Phosphatidylserine synthetase mutants of Escherichia coli. Genetic mapping and membrane phospholipid composition J. Biol. Chem. 251 1976 3242 3249
59. B.R. Ganong, J.M. Leonard, and C.R. Raetz Phosphatidic acid accumulation in the membranes of Escherichia coli mutants defective in CDP-diglyceride synthetase J. Biol. Chem. 255 1980 1623 1629
60. T. Icho, and C.R. Raetz Multiple genes for membrane-bound phosphatases in Escherichia coli and their action on phospholipid precursors J. Bacteriol. 153 1983 722 730
61. C.R. Raetz, M.M. Wermuth, T.M. McIntyre, J.D. Esko, and D.C. Wing Somatic cell cloning in polyester stacks Proc. Natl. Acad. Sci. U. S. A. 79 1982 3223 3227
62. M.J. Homann, and G.M. Carman Detection of phospholipid biosynthetic enzyme activities in Saccharomyces cerevisiae by colony autoradiography Anal. Biochem. 135 1983 447 452
63. E. Hawrot, and E.P. Kennedy Biogenesis of membrane lipids: mutants of Escherichia coli with temperature-sensitive phosphatidylserine decarboxylase Proc. Natl. Acad. Sci. U. S. A. 72 1975 1112 1116
64. E. Hawrot, and E.P. Kennedy Conditional lethal phosphatidylserine decarboxylase mutants of Escherichia coli. Mapping of the structural gene for phosphatidylserine decarboxylase Mol. Gen. Genet. 148 1976 271 279
65. E. Hawrot, and E.P. Kennedy Phospholipid composition and membrane function in phosphatidylserine decarboxylase mutants of Escherichia coli J. Biol. Chem. 253 1978 8213 8220
66. G. Pluschke, Y. Hirota, and P. Overath Function of phospholipids in Escherichia coli. Characterization of a mutant deficient in cardiolipin synthesis J. Biol. Chem. 253 1978 5048 5055
67. W. Dowhan, W.T. Wickner, and E.P. Kennedy Purification and properties of phosphatidylserine decarboxylase from Escherichia coli J. Biol. Chem. 249 1974 3079 3084
68. T.G. Warner, and E.A. Dennis Action of the highly purified, membrane-bound enzyme phosphatidylserine decarboxylase Escherichia coli toward phosphatidylserine in mixed micelles and erythrocyte ghosts in the presence of surfactant J. Biol. Chem. 250 1975 8004 8009
69. G.M. Carman, R.A. Deems, and E.A. Dennis Lipid signaling enzymes and surface dilution kinetics J. Biol. Chem. 270 1995 18711 18714
70. M. Satre, and E.P. Kennedy Identification of bound pyruvate essential for the activity of phosphatidylserine decarboxylase of Escherichia coli J. Biol. Chem. 253 1978 479 483
71. Q.X. Li, and W. Dowhan Structural characterization of Escherichia coli phosphatidylserine decarboxylase J. Biol. Chem. 263 1988 11516 11522
72. W.D. Riley, and E.E. Snell Histidine decarboxylase of Lactobacillus 30a. V. Origin of enzyme-bound pyruvate and separation of nonidentical subunits Biochemistry 9 1970 1485 1491
73. R.J. Tyhach, E. Hawrot, M. Satre, and E.P. Kennedy Increased synthesis of phosphatidylserine decarboxylase in a strain of Escherichia coli bearing a hybrid plasmid. Altered association of enzyme with the membrane J. Biol. Chem. 254 1979 627 633
74. Q.X. Li, and W. Dowhan Studies on the mechanism of formation of the pyruvate prosthetic group of phosphatidylserine decarboxylase from Escherichia coli J. Biol. Chem. 265 1990 4111 4115
75. C.J. Clancey, S.C. Chang, and W. Dowhan Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant J. Biol. Chem. 268 1993 24580 24590
76. P.J. Trotter, J. Pedretti, and D.R. Voelker Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele J. Biol. Chem. 268 1993 21416 21424
77. D.R. Voelker Phosphatidylserine decarboxylase Biochim. Biophys. Acta 1348 1997 236 244
78. K. Matsumoto Phosphatidylserine synthase from bacteria Biochim. Biophys. Acta 1348 1997 214 227
79. M.S. Bae-Lee, and G.M. Carman Phosphatidylserine synthesis in Saccharomyces cerevisiae. Purification and characterization of membrane-associated phosphatidylserine synthase J. Biol. Chem. 259 1984 10857 10862
80. C.R. Raetz, and E.P. Kennedy The association of phosphatidylserine synthetase with ribosomes in extracts of Escherichia coli J. Biol. Chem. 247 1972 2008 2014
81. C.R. Raetz, and E.P. Kennedy Partial purification and properties of phosphatidylserine synthetase from Escherichia coli J. Biol. Chem. 249 1974 5038 5045
82. C.R. Raetz, and E.P. Kennedy Function of cytidine diphosphate-diglyceride and deoxycytidine diphosphate-diglyceride in the biogenesis of membrane lipids in Escherichia coli J. Biol. Chem. 248 1973 1098 1105
83. C.R. Raetz, C.B. Hirschberg, W. Dowhan, W.T. Wickner, and E.P. Kennedy A membrane-bound pyrophosphatase in Escherichia coli catalyzing the hydrolysis of cytidine diphosphate-diglyceride J. Biol. Chem. 247 1972 2245 2247
84. C.R. Raetz, W. Dowhan, and E.P. Kennedy Partial purification and characterization of cytidine 5′-diphosphate-diglyceride hydrolase from membranes of Escherichia coli J. Bacteriol. 125 1976 855 863
85. C.E. Bulawa, J.D. Hermes, and C.R. Raetz Chloroform-soluble nucleotides in Escherichia coli. Role of CDP-diglyceride in the enzymatic cytidylylation of phosphomonoester acceptors J. Biol. Chem. 258 1983 14974 14980
86. C.R. Raetz, G.M. Carman, W. Dowhan, R.T. Jiang, W. Waszkuc, W. Loffredo, and M.D. Tsai Phospholipids chiral at phosphorus. Steric course of the reactions catalyzed by phosphatidylserine synthase from Escherichia coli and yeast Biochemistry 26 1987 4022 4027
87. T.J. Larson, and W. Dowhan Ribosomal-associated phosphatidylserine synthetase from Escherichia coli: purification by substrate-specific elution from phosphocellulose using cytidine 5′-diphospho-1,2-diacyl-sn-glycerol Biochemistry 15 1976 5212 5218
88. L. Clarke, and J. Carbon A colony bank containing synthetic Col El hybrid plasmids representative of the entire E. coli genome Cell 9 1976 91 99
89. C.R. Raetz, T.J. Larson, and W. Dowhan Gene cloning for the isolation of enzymes of membrane lipid synthesis: phosphatidylserine synthase overproduction in Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 74 1977 1412 1416
90. A. Ohta, K. Waggoner, K. Louie, and W. Dowhan Cloning of genes involved in membrane lipid synthesis. Effects of amplification of phosphatidylserine synthase in Escherichia coli J. Biol. Chem. 256 1981 2219 2225
91. K. Louie, and W. Dowhan Investigations on the association of phosphatidylserine synthase with the ribosomal component from Escherichia coli J. Biol. Chem. 255 1980 1124 1127
92. K. Louie, Y.C. Chen, and W. Dowhan Substrate-induced membrane association of phosphatidylserine synthase from Escherichia coli J. Bacteriol. 165 1986 805 812
93. A. DeChavigny, P.N. Heacock, and W. Dowhan Sequence and inactivation of the pss gene of Escherichia coli. Phosphatidylethanolamine may not be essential for cell viability J. Biol. Chem. 266 1991 5323 5332
94. G.M. Carman, and W. Dowhan Phosphatidylserine synthase from Escherichia coli. The role of Triton X-100 in catalysis J. Biol. Chem. 254 1979 8391 8397
95. T.J. Larson, T. Hirabayshi, and W. Dowhan Phosphatidylglycerol biosynthesis in Bacillus licheniformis. Resolution of membrane-bound enzymes by affinity chromatography on cytidinediphospho-sn-1,2-diacylglycerol Sepharose Biochemistry 15 1976 974 979
96. T. Hirabayashi, T.J. Larson, and W. Dowhan Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5′-diphospho-1,2-diacyl-sn- glycerol sepharose Biochemistry 15 1976 5205 5211
97. A. Ohta, K. Waggoner, A. Radominska-Pyrek, and W. Dowhan Cloning of genes involved in membrane lipid synthesis: effects of amplification of phosphatidylglycerophosphate synthase in Escherichia coli J. Bacteriol. 147 1981 552 562
98. M. Nishijima, and C.R. Raetz Membrane lipid biogenesis in Escherichia coli: identification of genetic loci for phosphatidylglycerophosphate synthetase and construction of mutants lacking phosphatidylglycerol J. Biol. Chem. 254 1979 7837 7844
99. A.S. Gopalakrishnan, Y.C. Chen, M. Temkin, and W. Dowhan Structure and expression of the gene locus encoding the phosphatidylglycerophosphate synthase of Escherichia coli J. Biol. Chem. 261 1986 1329 1338
100. A.M. Maxam, and W. Gilbert Sequencing end-labeled DNA with base-specific chemical cleavages Methods Enzymol. 65 1980 499 560
101. M. Usui, H. Sembongi, H. Matsuzaki, K. Matsumoto, and I. Shibuya Primary structures of the wild-type and mutant alleles encoding the phosphatidylglycerophosphate synthase of Escherichia coli J. Bacteriol. 176 1994 3389 3392
102. V.A. Lightner, R.M. Bell, and P. Modrich The DNA sequences encoding plsB and dgk loci of Escherichia coli J. Biol. Chem. 258 1983 10856 10861
103. T. Icho, C.E. Bulawa, and C.R. Raetz Molecular cloning and sequencing of the gene for CDP-diglyceride hydrolase of Escherichia coli J. Biol. Chem. 260 1985 12092 12098
104. C.R. Raetz, C.M. Reynolds, M.S. Trent, and R.E. Bishop Lipid A modification systems in gram-negative bacteria Annu. Rev. Biochem. 76 2007 295 329
105. M. Nishijima, and C.R. Raetz Characterization of two membrane-associated glycolipids from an Escherichia coli mutant deficient in phosphatidylglycerol J. Biol. Chem. 256 1981 10690 10696
106. C.R. Raetz Molecular genetics of membrane phospholipid synthesis Annu. Rev. Genet. 20 1986 253 295
107. W. Dowhan The Raetz pathway for lipid A biosynthesis: Christian Rudolf Hubert Raetz, MD PhD, 1946-2011 J. Lipid Res. 52 2011 1857 1860
108. W.T. Wickner, J. Stubbe, C.B. Hirschberg, T. Garrett, and W. Dowhan Chris Raetz, scientist and enduring friend Proc. Natl. Acad. Sci. U. S. A. 108 2011 17255 17256
109. B.R. Ganong, and C.R. Raetz Massive accumulation of phosphatidic acid in conditionally lethal CDP-diglyceride synthetase mutants and cytidine auxotrophs of Escherichia coli J. Biol. Chem. 257 1982 389 394
110. C.P. Sparrow, and C.R. Raetz Purification and properties of the membrane-bound CDP-diglyceride synthetase from Escherichia coli J. Biol. Chem. 260 1985 12084 12091
111. H. Shen, P.N. Heacock, C.J. Clancey, and W. Dowhan The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth J. Biol. Chem. 271 1996 789 795
112. L. Wu, B. Niemeyer, N. Colley, M. Socolich, and C.S. Zuker Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase Nature 373 1995 216 222
113. R. Weeks, W. Dowhan, H. Shen, N. Balantac, B. Meengs, E. Nudelman, and D.W. Leung Isolation and expression of an isoform of human CDP-diacylglycerol synthase cDNA DNA Cell Biol. 16 1997 281 289
114. T. Icho Membrane-bound phosphatases in Escherichia coli: sequence of the pgpA gene J. Bacteriol. 170 1988 5110 5116
115. T. Icho Membrane-bound phosphatases in Escherichia coli: sequence of the pgpB gene and dual subcellular localization of the pgpB product J. Bacteriol. 170 1988 5117 5124
116. T. Touze, D. Blanot, and D. Mengin-Lecreulx Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase J. Biol. Chem. 283 2008 16573 16583
117. C.R. Funk, L. Zimniak, and W. Dowhan The pgpA and pgpB genes of Escherichia coli are not essential: evidence for a third phosphatidylglycerophosphate phosphatase J. Bacteriol. 174 1992 205 213
118. C. Osman, M. Haag, F.T. Wieland, B. Brügger, and T. Langer A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4 EMBO J. 29 2010 1976 1987
119. J. Zhang, Z. Guan, A.N. Murphy, S.E. Wiley, G.A. Perkins, C.A. Worby, J.L. Engel, P. Heacock, O.K. Nguyen, J.H. Wang, C.R. Raetz, W. Dowhan, and J.E. Dixon Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis Cell Metab. 13 2011 690 700
120. A. Ohta, T. Obara, Y. Asami, and I. Shibuya Molecular cloning of the cls gene responsible for cardiolipin synthesis in Escherichia coli and phenotypic consequences of its amplification J. Bacteriol. 163 1985 506 514
121. S. Hiraoka, K. Nukui, N. Uetake, A. Ohta, and I. Shibuya Amplification and substantial purification of cardiolipin synthase of Escherichia coli J. Biochem. 110 1991 443 449
122. B.R. Quigley, and B.E. Tropp E. coli cardiolipin synthase: function of N-terminal conserved residues Biochim. Biophys. Acta 1788 2009 2107 2113
123. D. Guo, and B.E. Tropp A second Escherichia coli protein with CL synthase activity Biochim. Biophys. Acta 1483 2000 263 274
124. I. Shibuya, S. Yamagoe, C. Miyazaki, H. Matsuzaki, and A. Ohta Biosynthesis of novel acidic phospholipid analogs in Escherichia coli J. Bacteriol. 161 1985 473 477
125. S. Nishijima, Y. Asami, N. Uetake, S. Yamagoe, A. Ohta, and I. Shibuya Disruption of the Escherichia coli cls gene responsible for cardiolipin synthesis J. Bacteriol. 170 1988 775 780
126. A.M. Michaelis, and Z. Gitai Dynamic polar sequestration of excess MurG may regulate enzymatic function J. Bacteriol. 192 2010 4597 4605
127. S. Hiraoka, H. Matsuzaki, and I. Shibuya Active increase in cardiolipin synthesis in the stationary growth phase and its physiological significance in Escherichia coli FEBS Lett. 336 1993 221 224
128. M. Serricchio, and P. Bütikofer An essential bacterial-type cardiolipin synthase mediates cardiolipin formation in a eukaryote Proc. Natl. Acad. Sci. U. S. A. 109 2012 E954 E961
129. I. Shibuya, C. Miyazaki, and A. Ohta Alteration of phospholipid composition by combined defects in phosphatidylserine and cardiolipin synthases and physiological consequences in Escherichia coli J. Bacteriol. 161 1985 1086 1092
130. L.M.G. van Golde, H. Schulman, and E.P. Kennedy Metabolism of membrane phospholipids and its relation to a novel class of oligosaccharides in Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 70 1973 1368 1372
131. E.P. Kennedy, M.K. Rumley, H. Schulman, and L.M. Van Golde Identification of sn-glycero-1-phosphate and phosphoethanolamine residues linked to the membrane-derived Oligosaccharides of Escherichia coli J. Biol. Chem. 251 1976 4208 4213
132. J.E. Schneider, V. Reinhold, M.K. Rumley, and E.P. Kennedy Structural studies of the membrane-derived oligosaccharides of Escherichia coli J. Biol. Chem. 254 1979 10135 10138
133. H. Schulman, and E.P. Kennedy Identification of UDP-glucose as an intermediate in the biosynthesis of the membrane-derived oligosaccharides of Escherichia coli J. Biol. Chem. 252 1977 6299 6303
134. B.J. Jackson, and E.P. Kennedy The biosynthesis of membrane-derived oligosaccharides. A membrane-bound phosphoglycerol transferase J. Biol. Chem. 258 1983 2394 2398
135. C.R. Raetz, and K.F. Newman Diglyceride kinase mutants of Escherichia coli: inner membrane association of 1,2-diglyceride and its relation to synthesis of membrane-derived oligosaccharides J. Bacteriol. 137 1979 860 868
136. K.J. Miller, E.P. Kennedy, and V.N. Reinhold Osmotic adaptation by gram-negative bacteria: possible role for periplasmic oligosaccharides Science 231 1986 48 51
137. A.C. Weissborn, M.K. Rumley, and E.P. Kennedy Isolation and characterization of Escherichia coli mutants blocked in production of membrane-derived oligosaccharides J. Bacteriol. 174 1992 4856 4859
138. S.D. Gupta, W. Dowhan, and H.C. Wu Phosphatidylethanolamine is not essential for the N-acylation of apolipoprotein in Escherichia coli J. Biol. Chem. 266 1991 9983 9986
139. 2 + hypersensitivity of an eptB deletion mutant J. Biol. Chem. 280 2005 21202 21211
140. N. Yamamoto, K. Nakahigashi, T. Nakamichi, M. Yoshino, Y. Takai, Y. Touda, A. Furubayashi, S. Kinjyo, H. Dose, M. Hasegawa, K.A. Datsenko, T. Nakayashiki, M. Tomita, B.L. Wanner, and H. Mori Update on the Keio collection of Escherichia coli single-gene deletion mutants Mol. Syst. Biol. 5 2009 335
141. K.A. Datsenko, and B.L. Wanner One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products Proc. Natl. Acad. Sci. U. S. A. 97 2000 6640 6645
142. P.N. Heacock, and W. Dowhan Construction of a lethal mutation in the synthesis of the major acidic phospholipids of Escherichia coli J. Biol. Chem. 262 1987 13044 13049
143. P.N. Heacock, and W. Dowhan Alteration of the phospholipid composition of Escherichia coli through genetic manipulation J. Biol. Chem. 264 1989 14972 14977
144. P.J. Choi, L. Cai, K. Frieda, and X.S. Xie A stochastic single-molecule event triggers phenotype switching of a bacterial cell Science 322 2008 442 446
145. C. Miyazaki, M. Kuroda, A. Ohta, and I. Shibuya Genetic manipulation of membrane phospholipid composition in Escherichia coli: pgsA mutants defective in phosphatidylglycerol synthesis Proc. Natl. Acad. Sci. U. S. A. 82 1985 7530 7534
146. Y. Asai, Y. Katayose, C. Hikita, A. Ohta, and I. Shibuya Suppression of the lethal effect of acidic-phospholipid deficiency by defective formation of the major outer membrane lipoprotein in Escherichia coli J. Bacteriol. 171 1989 6867 6869
147. H.C. Wu Biosynthesis of lipoproteins F.C. Neidhardt, R. Curtiss III J.L. Ingraham, E.C.C. Lin, K.B. Low, B. Magasanik, W.S. Reznikoff, M. Riley, M. Schaechter, H.E. Umbarger, Escherichia coli and Salmonella: Cellular and Molecular Biology 1996 ASM Press Washington, D.C. 1005 1014
148. M. Suzuki, H. Hara, and K. Matsumoto Envelope disorder of Escherichia coli cells lacking phosphatidylglycerol J. Bacteriol. 184 2002 5418 5425
149. S. Kikuchi, I. Shibuya, and K. Matsumoto Viability of an Escherichia coli pgsA null mutant lacking detectable phosphatidylglycerol and cardiolipin J. Bacteriol. 182 2000 371 376
150. H. Nagahama, Y. Sakamoto, K. Matsumoto, and H. Hara RcsA-dependent and -independent growth defects caused by the activated Rcs phosphorelay system in the Escherichia coli pgsA null mutant J. Gen. Appl. Microbiol. 52 2006 91 98
151. Y. Shiba, Y. Yokoyama, Y. Aono, T. Kiuchi, J. Kusaka, K. Matsumoto, and H. Hara Activation of the Rcs signal transduction system is responsible for the thermosensitive growth defect of an Escherichia coli mutant lacking phosphatidylglycerol and cardiolipin J. Bacteriol. 186 2004 6526 6535
152. Y. Shiba, H. Miyagawa, H. Nagahama, K. Matsumoto, D. Kondo, S. Matsuoka, and H. Hara Exploring the relationship between lipoprotein mislocalization and activation of the Rcs signal transduction system in Escherichia coli Microbiology 158 2012 1238 1248
153. T. de Vrije, R.L. de Swart, W. Dowhan, J. Tommassen, and B. de Kruijff Phosphatidylglycerol is involved in protein translocation across Escherichia coli inner membranes Nature 334 1988 173 175
154. R. Kusters, W. Dowhan, and B. de Kruijff Negatively charged phospholipids restore prePhoE translocation across phosphatidylglycerol-depleted Escherichia coli inner membranes J. Biol. Chem. 266 1991 8659 8662
155. R. Lill, W. Dowhan, and W. Wickner The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins Cell 60 1990 271 280
156. B.Y. Yung, and A. Kornberg Membrane attachment activates DnaA protein, the initiation protein of chromosome replication in Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 85 1988 7202 7205
157. W. Xia, and W. Dowhan In vivo evidence for the involvement of anionic phospholipids in initiation of DNA replication in Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 92 1995 783 787
158. J. Garner, P. Durrer, J. Kitchen, J. Brunner, and E. Crooke Membrane-mediated release of nucleotide from an initiator of chromosomal replication, Escherichia coli DnaA, occurs with insertion of a distinct region of the protein into the lipid bilayer J. Biol. Chem. 273 1998 5167 5173
159. J.L. Kitchen, Z. Li, and E. Crooke Electrostatic interactions during acidic phospholipid reactivation of DnaA protein, the Escherichia coli initiator of chromosomal replication Biochemistry 38 1999 6213 6221
160. Z. Li, J.L. Kitchen, K. Boeneman, P. Anand, and E. Crooke Restoration of growth to acidic phospholipid-deficient cells by DnaA(L366K) is independent of its capacity for nucleotide binding and exchange and requires DnaA J. Biol. Chem. 280 2005 9796 9801
161. E. Mileykovskaya, and W. Dowhan Role of membrane lipids in bacterial division-site selection Curr. Opin. Microbiol. 8 2005 135 142
162. E. Mileykovskaya, I. Fishov, X. Fu, B.D. Corbin, W. Margolin, and W. Dowhan Effects of phospholipid composition on MinD-membrane interactions in vitro and in vivo J. Biol. Chem. 278 2003 22193 22198
163. E. Mileykovskaya, and W. Dowhan Visualization of phospholipid domains in Escherichia coli by using the cardiolipin-specific fluorescent dye 10-N-nonyl acridine orange J. Bacteriol. 182 2000 1172 1175
164. C.M. Koppelman, T. Den Blaauwen, M.C. Duursma, R.M. Heeren, and N. Nanninga Escherichia coli minicell membranes are enriched in cardiolipin J. Bacteriol. 183 2001 6144 6147
165. S. Mazor, T. Regev, E. Mileykovskaya, W. Margolin, W. Dowhan, and I. Fishov Mutual effects of MinD-membrane interaction: I. Changes in the membrane properties induced by MinD binding Biochim. Biophys. Acta 1778 2008 2496 2504
166. S. Mazor, T. Regev, E. Mileykovskaya, W. Margolin, W. Dowhan, and I. Fishov Mutual effects of MinD-membrane interaction: II. Domain structure of the membrane enhances MinD binding Biochim. Biophys. Acta 1778 2008 2505 2511
167. E. Mileykovskaya, A.C. Ryan, X. Mo, C.C. Lin, K.I. Khalaf, W. Dowhan, and T.A. Garrett Phosphatidic acid and N-acylphosphatidylethanolamine form membrane domains in Escherichia coli mutant lacking cardiolipin and phosphatidylglycerol J. Biol. Chem. 284 2009 2990 3000
168. C.R. Raetz, G.D. Kantor, M. Nishijima, and K.F. Newman Cardiolipin accumulation in the inner and outer membranes of Escherichia coli mutants defective in phosphatidylserine synthetase J. Bacteriol. 139 1979 544 551
169. Q.-X. Li, Structure and biosynthesis of a pyruvate-dependent enzyme: phosphatidylserine decarboxylase from Escherichia coli, in: Department of Biochemistry and Molecular Biology, vol. Ph.D., University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences, Houston, TX, 1989, pp. 110.
170. A.G. Rietveld, J.A. Killian, W. Dowhan, and B. de Kruijff Polymorphic regulation of membrane phospholipid composition in Escherichia coli J. Biol. Chem. 268 1993 12427 12433
171. 31P NMR study Biochim. Biophys. Acta 513 1978 31 42
172. 31P NMR and freeze-fracture techniques. Effects of calcium, dibucaine and chlorpromazine Biochim. Biophys. Acta 513 1978 11 20
173. 2 + and temperature Biochim. Biophys. Acta 684 1982 282 286
174. A.G. Rietveld, V.V. Chupin, M.C. Koorengevel, H.L. Wienk, W. Dowhan, and B. de Kruijff Regulation of lipid polymorphism is essential for the viability of phosphatidylethanolamine-deficient Escherichia coli cells J. Biol. Chem. 269 1994 28670 28675
175. C.F. Chang, H. Shuman, and A.P. Somlyo Electron probe analysis, X-ray mapping, and electron energy-loss spectroscopy of calcium, magnesium, and monovalent ions in log-phase and in dividing Escherichia coli B cells J. Bacteriol. 167 1986 935 939
176. P. Gangola, and B.P. Rosen Maintenance of intracellular calcium in Escherichia coli J. Biol. Chem. 262 1987 12570 12574
177. C.R. Raetz, and J. Foulds Envelope composition and antibiotic hypersensitivity of Escherichia coli mutants defective in phosphatidylserine synthetase J. Biol. Chem. 252 1977 5911 5915
178. M. Wikström, J. Xie, M. Bogdanov, E. Mileykovskaya, P. Heacock, Ä. Wieslander, and W. Dowhan Monoglucosyldiacylglycerol, a foreign lipid, can substitute for phosphatidylethanolamine in essential membrane-associated functions in Escherichia coli J. Biol. Chem. 279 2004 10484 10493
179. 2 +-induced phosphoethanolamine transfer to the outer 3-deoxy-D-manno-octulosonic acid moiety of Escherichia coli lipopolysaccharide. A novel membrane enzyme dependent upon phosphatidylethanolamine J. Biol. Chem. 276 2001 1156 1163
180. M. Bogdanov, P.N. Heacock, and W. Dowhan A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition EMBO J. 21 2002 2107 2116
181. D.A. Siegele, and J.C. Hu Gene expression from plasmids containing the araBAD promoter at subsaturating inducer concentrations represents mixed populations Proc. Natl. Acad. Sci. U. S. A. 94 1997 8168 8172
182. R. Bertram, and W. Hillen The application of Tet repressor in prokaryotic gene regulation and expression Microb. Biotechnol. 1 2008 2 16
183. M. Bogdanov, and W. Dowhan Lipid-dependent generation of a dual topology for a membrane protein J. Biol. Chem. 2012 (submitted)
184. M. Bogdanov, J. Xie, P. Heacock, and W. Dowhan To flip or not to flip: lipid-protein charge interactions are a determinant of final membrane protein topology J. Cell Biol. 182 2008 925 935
185. M. Bogdanov, P. Heacock, Z. Guan, and W. Dowhan Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 107 2010 15057 15062
186. W. Xia, and W. Dowhan Phosphatidylinositol cannot substitute for phosphatidylglycerol in supporting cell growth of Escherichia coli J. Bacteriol. 177 1995 2926 2928
187. Y. Oku, K. Kurokawa, N. Ichihashi, and K. Sekimizu Characterization of the Staphylococcus aureus mprF gene, involved in lysinylation of phosphatidylglycerol Microbiology 150 2004 45 51
188. M. Bogdanov, J. Xie, and W. Dowhan Lipid-protein interactions drive membrane protein topogenesis in accordance with the positive inside rule J. Biol. Chem. 284 2009 9637 9641
189. J.R. Carter, C.F. Fox, and E.P. Kennedy Interaction of sugars with the membrane protein component of the lactose transport system of Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 60 1968 725 732
190. C.F. Fox, J.R. Carter, and E.P. Kennedy Genetic control of the membrane protein component of the lactose transport system of Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 57 1967 698 705
191. E.P. Kennedy, C.F. Fox, and J.R. Carter Membrane structure and function J. Gen. Physiol. 49 1966 347 354
192. C.F. Fox, and E.P. Kennedy Specific labeling and partial purification of the M protein, a component of the beta-galactoside transport system of Escherichia coli Proc. Natl. Acad. Sci. U. S. A. 54 1965 891 899
193. M.J. Newman, D.L. Foster, T.H. Wilson, and H.R. Kaback Purification and reconstitution of functional lactose carrier from Escherichia coli J. Biol. Chem. 256 1981 11804 11808
194. M.J. Newman, and T.H. Wilson Solubilization and reconstitution of the lactose transport system from Escherichia coli J. Biol. Chem. 255 1980 10583 10586
195. C.C. Chen, and T.H. Wilson The phospholipid requirement for activity of the lactose carrier of Escherichia coli J. Biol. Chem. 259 1984 10150 10158
196. D. Seto-Young, C.C. Chen, and T.H. Wilson Effect of different phospholipids on the reconstitution of two functions of the lactose carrier of Escherichia coli J. Membr. Biol. 84 1985 259 267
197. W. Dowhan, and M. Bogdanov Lipid-dependent membrane protein topogenesis Annu. Rev. Biochem. 78 2009 515 540
198. M. Bogdanov, and W. Dowhan Phosphatidylethanolamine is required for in vivo function of the membrane-associated lactose permease of Escherichia coli J. Biol. Chem. 270 1995 732 739
199. J. Abramson, I. Smirnova, V. Kasho, G. Verner, H.R. Kaback, and S. Iwata Structure and mechanism of the lactose permease of Escherichia coli Science 301 2003 610 615
200. J. Sun, J. Wu, N. Carrasco, and H.R. Kaback Identification of the epitope for monoclonal antibody 4B1 which uncouples lactose and proton translocation in the lactose permease of Escherichia coli Biochemistry 35 1996 990 998
201. S. Frillingos, and H.R. Kaback Monoclonal antibody 4B1 alters the pKa of a carboxylic acid at position 325 (helix X) of the lactose permease of Escherichia coli Biochemistry 35 1996 10166 10171
202. S. Frillingos, J. Wu, P. Venkatesan, and H.R. Kaback Binding of ligand or monoclonal antibody 4B1 induces discrete structural changes in the lactose permease of Escherichia coli Biochemistry 36 1997 6408 6414
203. M. Bogdanov, J. Sun, H.R. Kaback, and W. Dowhan A phospholipid acts as a chaperone in assembly of a membrane transport protein J. Biol. Chem. 271 1996 11615 11618
204. M. Bogdanov, and W. Dowhan Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease EMBO J. 17 1998 5255 5264
205. M. Bogdanov, and W. Dowhan Lipid-assisted protein folding J. Biol. Chem. 274 1999 36827 36830
206. M. Bogdanov, M. Umeda, and W. Dowhan Phospholipid-assisted refolding of an integral membrane protein. Minimum structural features for phosphatidylethanolamine to act as a molecular chaperone J. Biol. Chem. 274 1999 12339 12345
207. H.R. Kaback, M. Sahin-Toth, and A.B. Weinglass The kamikaze approach to membrane transport Nat. Rev. Mol. Cell Biol. 2 2001 610 620
208. L. Guan, O. Mirza, G. Verner, S. Iwata, and H.R. Kaback Structural determination of wild-type lactose permease Proc. Natl. Acad. Sci. U. S. A. 104 2007 15294 15298
209. M. Bogdanov, P.N. Heacock, and W. Dowhan Study of polytopic membrane protein topological organization as a function of membrane lipid composition Methods Mol. Biol. 619 2010 79 101
210. TM): application to lipid-specific membrane protein topogenesis Methods 36 2005 148 171
211. M. Wikström, A.A. Kelly, A. Georgiev, H.M. Eriksson, M.R. Klement, M. Bogdanov, W. Dowhan, and Ä. Wieslander Lipid-engineered Escherichia coli membranes reveal critical lipid headgroup size for protein function J. Biol. Chem. 284 2009 954 965
212. J. Xie, M. Bogdanov, P. Heacock, and W. Dowhan Phosphatidylethanolamine and monoglucosyldiacylglycerol are interchangeable in supporting topogenesis and function of the polytopic membrane protein lactose permease J. Biol. Chem. 281 2006 19172 19178
213. W. Zhang, M. Bogdanov, J. Pi, A.J. Pittard, and W. Dowhan Reversible topological organization within a polytopic membrane protein is governed by a change in membrane phospholipid composition J. Biol. Chem. 278 2003 50128 50135
214. W. Zhang, H.A. Campbell, S.C. King, and W. Dowhan Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the gamma-aminobutyric acid permease (GabP) of Escherichia coli J. Biol. Chem. 280 2005 26032 26038
215. H. Vitrac, M. Bogdanov, P. Heacock, and W. Dowhan Lipids and topological rules of membrane protein assembly: balance between long and short range lipid-protein interactions J. Biol. Chem. 286 2011 15182 15194
216. I. Nilsson, and G. von Heijne Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids Cell 62 1990 1135 1141
217. X. Wang, M. Bogdanov, and W. Dowhan Topology of polytopic membrane protein subdomains is dictated by membrane phospholipid composition EMBO J. 21 2002 5673 5681
218. S.C. Chang, P.N. Heacock, C.J. Clancey, and W. Dowhan The PEL1 gene (renamed PGS1) encodes the phosphatidylglycero-phosphate synthase of Saccharomyces cerevisiae J. Biol. Chem. 273 1998 9829 9836
219. S.C. Chang, P.N. Heacock, E. Mileykovskaya, D.R. Voelker, and W. Dowhan Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae J. Biol. Chem. 273 1998 14933 14941
220. M. Zhang, E. Mileykovskaya, and W. Dowhan Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane J. Biol. Chem. 277 2002 43553 43556
221. M. Zhang, E. Mileykovskaya, and W. Dowhan Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria J. Biol. Chem. 280 2005 29403 29408
222. E.I. Mileykovskaya, and W. Dowhan Alterations in the electron transfer chain in mutant strains of Escherichia coli lacking phosphatidylethanolamine J. Biol. Chem. 268 1993 24824 24831
223. E. Mileykovskaya, and W. Dowhan The Cpx two-component signal transduction pathway is activated in Escherichia coli mutant strains lacking phosphatidylethanolamine J. Bacteriol. 179 1997 1029 1034
224. E. Mileykovskaya, Q. Sun, W. Margolin, and W. Dowhan Localization and function of early cell division proteins in filamentous Escherichia coli cells lacking phosphatidylethanolamine J. Bacteriol. 180 1998 4252 4257
225. K. Iwamoto, S. Kobayashi, R. Fukuda, M. Umeda, T. Kobayashi, and A. Ohta Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity Genes Cells 9 2004 891 903
226. K. Emoto, and M. Umeda An essential role for a membrane lipid in cytokinesis. Regulation of contractile ring disassembly by redistribution of phosphatidylethanolamine J. Cell Biol. 149 2000 1215 1224
227. W. Shi, M. Bogdanov, W. Dowhan, and D.R. Zusman The pss and psd genes are required for motility and chemotaxis in Escherichia coli J. Bacteriol. 175 1993 7711 7714
228. M. Kates, J.Y. Syz, D. Gosser, and T.H. Haines pH-dissociation characteristics of cardiolipin and its 2′-deoxy analogue Lipids 28 1993 877 882
229. 2 revealed by single particle cryo-electron microscopy J. Biol. Chem. 287 2012 23095 23103
230. H. Palsdottir, and C. Hunte Lipids in membrane protein structures Biochim. Biophys. Acta 1666 2004 2 18
231. K. Shinzawa-Itoh, H. Aoyama, K. Muramoto, H. Terada, T. Kurauchi, Y. Tadehara, A. Yamasaki, T. Sugimura, S. Kurono, K. Tsujimoto, T. Mizushima, E. Yamashita, T. Tsukihara, and S. Yoshikawa Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase EMBO J. 26 2007 1713 1725
232. H. Schägger, and K. Pfeiffer Supercomplexes in the respiratory chains of yeast and mammalian mitochondria EMBO J. 19 2000 1777 1783
233. R.A. Stuart Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria J. Biol. Chem. 40 2008 411 417
234. I. Wittig, and H. Schägger Supramolecular organization of ATP synthase and respiratory chain in mitochondrial membranes Biochim. Biophys. Acta 1787 2009 672 680
235. K. Kawasaki, O. Kuge, S.C. Chang, P.N. Heacock, M. Rho, K. Suzuki, M. Nishijima, and W. Dowhan Isolation of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylglycerophosphate (PGP) synthase, expression of which corrects the mitochondrial abnormalities of a PGP synthase-defective mutant of CHO-K1 cells J. Biol. Chem. 274 1999 1828 1834
236. E. Mileykovskaya, and W. Dowhan Cardiolipin membrane domains in prokaryotes and eukaryotes Biochim. Biophys. Acta 1788 2009 2084 2091
237. E. Mileykovskaya, W. Dowhan, R.L. Birke, D. Zheng, L. Lutterodt, and T.H. Haines Cardiolipin binds nonyl acridine orange by aggregating the dye at exposed hydrophobic domains on bilayer surfaces FEBS Lett. 507 2001 187 190
238. K.C. Huang, R. Mukhopadhyay, and N.S. Wingreen A curvature-mediated mechanism for localization of lipids to bacterial poles PLoS Comput. Biol. 2 2006 e151
239. R. Mukhopadhyay, K.C. Huang, and N.S. Wingreen Lipid localization in bacterial cells through curvature-mediated microphase separation Biophys. J. 95 2008 1034 1049
240. K. Matsumoto, J. Kusaka, A. Nishibori, and H. Hara Lipid domains in bacterial membranes Mol. Microbiol. 61 2006 1110 1117
241. W.O. Wilkison, J.P. Walsh, J.M. Corless, and R.M. Bell Crystalline arrays of the Escherichia coli sn-glycerol-3-phosphate acyltransferase, an integral membrane protein J. Biol. Chem. 261 1986 9951 9958
242. T.M. McIntyre, B.K. Chamberlain, R.E. Webster, and R.M. Bell Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effects of cessation and reinitiation of phospholipid synthesis on macromolecular synthesis and phospholipid turnover J. Biol. Chem. 252 1977 4487 4493
243. D. Clark, V. Lightner, R. Edgar, P. Modrich, J.E. Cronan Jr., and R.M. Bell Regulation of phospholipid biosynthesis in Escherichia coli. Cloning of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase J. Biol. Chem. 255 1980 714 717
244. S.K. Saha, S. Nishijima, H. Matsuzaki, I. Shibuya, and K. Matsumoto A regulatory mechanism for the balanced synthesis of membrane phospholipid species in Escherichia coli Biosci. Biotechnol. Biochem. 60 1996 111 116
245. K. Linde, G. Gröbner, and L. Rilfors Lipid dependence and activity control of phosphatidylserine synthase from Escherichia coli FEBS Lett. 575 2004 77 80
246. L. Rilfors, A. Niemi, S. Haraldsson, K. Edwards, A.S. Andersson, and W. Dowhan Reconstituted phosphatidylserine synthase from Escherichia coli is activated by anionic phospholipids and micelle-forming amphiphiles Biochim. Biophys. Acta 1438 1999 281 294
247. B.J. Jackson, J.M. Gennity, and E.P. Kennedy Regulation of the balanced synthesis of membrane phospholipids. Experimental test of models for regulation in Escherichia coli J. Biol. Chem. 261 1986 13464 13468
248. G.M. Conover, F. Martinez-Morales, M.I. Heidtman, Z.Q. Luo, M. Tang, C. Chen, O. Geiger, and R.R. Isberg Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants Cell. Microbiol. 10 2008 514 528