Monoclonal antibody 4B1 alters the pK(a) of a carboxylic acid at position 325 (Helix X) of the lactose permease of Escherichia coli

Biochemistry

Volumn 35, Issue 31, 1996, Pages 10166-10171

  Frillingos, Stathis ^a   Ronald Kaback, H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE PERMEASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 4B1; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; ARTICLE; CONFORMATIONAL TRANSITION; DNA HELIX; ELECTRICITY; ENZYME BINDING; ENZYME CONFORMATION; ESCHERICHIA COLI; PH; PKA; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ASPARTIC ACID; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; KINETICS; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SYMPORTERS;

COMOCLADIA GLABRA; ESCHERICHIA COLI;

EID: 0029781884     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960995r     Document Type: Article

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