CD9 is a novel marker for plasma cell precursors in human germinal centers

Biochemical and Biophysical Research Communications

Volumn 431, Issue 1, 2013, Pages 41-46

  Yoon, Sun Ok ^a   Zhang, Xin ^a   Lee, In Yong ^a   Spencer, Nakia ^a   Vo, Phuong ^a   Choi, Yong Sung ^a  

^a OCHSNER CLINIC FOUNDATION   (United States)

Author keywords

B cells; CD9; Differentiation; Germinal center; Plasma cells

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD9 ANTIGEN; PROTEIN BCL 6; TRANSCRIPTION FACTOR PAX5;

ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; GERMINAL CENTER; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TONSIL CELL;

ANTIGENS, CD9; B-LYMPHOCYTE SUBSETS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; GERMINAL CENTER; HUMANS; PALATINE TONSIL; PLASMA CELLS;

EID: 84873085350     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.12.102     Document Type: Article

References (22)

1. Wright M.D., Moseley G.W., van Spriel A.B. Tetraspanin microdomains in immune cell signalling and malignant disease. Tissue Antigens 2004, 64:533-542.
2. Hemler M.E. Tetraspanin functions and associated microdomains. Nat. Rev. Mol. Cell Biol. 2005, 6:801-811.
3. Maecker H.T., Todd S.C., Levy S. The tetraspanin superfamily: molecular facilitators. Faseb J. 1997, 11:428-442.
4. Boucheix C., Rubinstein E. Tetraspanins. Cell. Mol. Life Sci. 2001, 58:1189-1205.
5. Zoller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat. Rev. Cancer 2009, 9:40-55.
6. Sincock P.M., Mayrhofer G., Ashman L.K. Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin. J. Histochem. Cytochem. 1997, 45:515-525.
7. Kersey J.H., LeBien T.W., Abramson C.S., Newman R., Sutherland R., Greaves M. P-24: a human leukemia-associated and lymphohemopoietic progenitor cell surface structure identified with monoclonal antibody. J. Exp. Med. 1981, 153:726-731.
8. Won W.J., Kearney J.F. CD9 is a unique marker for marginal zone B cells, B1 cells, and plasma cells in mice. J. Immunol. 2002, 168:5605-5611.
9. Ha S.A., Tsuji M., Suzuki K., Meek B., Yasuda N., Kaisho T., Fagarasan S. Regulation of B1 cell migration by signals through Toll-like receptors. J. Exp. Med. 2006, 203:2541-2550.
10. Ko E.M., Lee I.Y., Cheon I.S., Kim J., Choi J.S., Hwang J.Y., Cho J.S., Lee D.H., Kang D., Kim S.H., Choe J. Monoclonal antibody to CD9 inhibits platelet-induced human endothelial cell proliferation. Mol. Cells 2006, 22:70-77.
11. Choe J., Kim H.S., Zhang X., Armitage R.J., Choi Y.S. Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-Ig down-regulates Fas expression of CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis. J. Immunol. 1996, 157:1006-1016.
12. Kim H.-S., Zhang X., Choi Y.S. Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes. J. Immunol. 1994, 153:2951-2961.
13. Yoon S.O., Zhang X., Berner P., Choi Y.S. IL-21 and IL-10 have redundant roles but differential capacities at different stages of Plasma Cell generation from human Germinal Center B cells. J. Leukoc. Biol. 2009, 86:1311-1318.
14. Diehl S.A., Schmidlin H., Nagasawa M., van Haren S.D., Kwakkenbos M.J., Yasuda E., Beaumont T., Scheeren F.A., Spits H. STAT3-mediated up-regulation of BLIMP1 is coordinated with BCL6 down-regulation to control human plasma cell differentiation. J. Immunol. 2008, 180:4805-4815.
15. Scheeren F.A., Naspetti M., Diehl S., Schotte R., Nagasawa M., Wijnands E., Gimeno R., Vyth-Dreese F.A., Blom B., Spits H. STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression. Nat. Immunol. 2005, 6:303-313.
16. Pascual V., Liu Y.-J., Magalski A., de Bouteiller O., Banchereau J., Capra J.D. Analysis of somatic mutation in five B cell subsets of human tonsil. J. Exp. Med. 1994, 180:329-339.
17. Calame K.L., Lin K.I., Tunyaplin C. Regulatory mechanisms that determine the development and function of plasma cells. Annu. Rev. Immunol. 2003, 21:205-230.
18. Turner C.A., Mack D.H., Davis M.M. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell 1994, 77:297-306.
19. Shaffer A.L., Yu X., He Y., Boldrick J., Chan E.P., Staudt L.M. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 2000, 13:199-212.
20. Nera K.P., Kohonen P., Narvi E., Peippo A., Mustonen L., Terho P., Koskela K., Buerstedde J.M., Lassila O. Loss of Pax5 promotes plasma cell differentiation. Immunity 2006, 24:283-293.
21. Angelin-Duclos C., Cattoretti G., Lin K.I., Calame K. Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J. Immunol. 2000, 165:5462-5471.
22. Choe J., Choi Y.S. Interleukin-10 interrupts memory B cell expansion in the germinal center by inducing differentiation into plasma. Eur. J. Immunol. 1998, 28:508-515.