Tranilast prevents atrial remodeling and development of atrial fibrillation in a canine model of atrial tachycardia and left ventricular dysfunction

Journal of the American College of Cardiology

Volumn 61, Issue 5, 2013, Pages 582-588

  Nakatani, Yosuke ^a   Nishida, Kunihiro ^a   Sakabe, Masao ^b   Kataoka, Naoya ^a   Sakamoto, Tamotsu ^a   Yamaguchi, Yoshiaki ^a   Iwamoto, Jotaro ^a   Mizumaki, Koichi ^a   Fujiki, Akira ^b   Inoue, Hiroshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b SHIZUOKA RED CROSS HOSPITAL   (Japan)

Author keywords

atrial fibrillation; atrial remodeling; tranilast; transforming growth factor 1

Indexed keywords

PLACEBO; RAC1 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANILAST; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIAL FIBROSIS; ATRIOVENTRICULAR CONDUCTION; CARDIOVASCULAR MALFORMATION; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DRUG ACTIVITY; HEART ATRIUM FIBRILLATION; HEART ATRIUM REMODELING; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE FIBROSIS; HEART PACING; HEART PROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAPID VENTRICULAR RESPONSE; SHAM PROCEDURE; SUPRAVENTRICULAR TACHYCARDIA;

ANIMALS; ATRIAL FIBRILLATION; CARDIAC PACING, ARTIFICIAL; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; DOGS; HEART ATRIA; ORTHO-AMINOBENZOATES; TACHYCARDIA; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84873081746     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.11.014     Document Type: Article

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