Residue-specific membrane location of peptides and proteins using specifically and extensively deuterated lipids and 13C-2H rotational-echo double-resonance solid-state NMR

Journal of Biomolecular NMR

Volumn 55, Issue 1, 2013, Pages 11-17

  Xie, Li ^a   Ghosh, Ujjayini ^a   Schmick, Scott D ^a   Weliky, David P ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

13C 2H; Deuterated lipid; Membrane location; Peptide; Protein; REDOR; Solid state NMR

Indexed keywords

CARBON 13; H 261; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; VIRUS PROTEIN;

ARTICLE; BETA SHEET; HYDROPHOBICITY; INFLUENZA VIRUS; LIPID ANALYSIS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; ROTATIONAL ECHO DOUBLE RESONANCE SOLID STATE NMR;

AMINO ACIDS; CARBON ISOTOPES; DEUTERIUM; LIPIDS; MEMBRANE PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES;

ORTHOMYXOVIRIDAE;

EID: 84873059119     PISSN: 09252738     EISSN: 15735001     Source Type: Journal    
DOI: 10.1007/s10858-012-9692-8     Document Type: Article

References (29)

1. 16-22, a seven-residue fragment of the Alzheimer's β-Amyloid peptide, and structural characterization by solid state NMR. Biochemistry 39:13748-13759
2. Brugger B, Glass B, Haberkant P, Leibrecht I, Wieland FT, Krasslich HG (2006) The HIV lipidome: a raft with an unusual composition. Proc Natl Acad Sci USA 103:2641-2646
3. 2+. Biophys J 85:2363-2373
4. Cady SD, Schmidt-Rohr K, Wang J, Soto CS, DeGrado WF, Hong M (2010) Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature 463:689-693
5. de Planque MRR, Goormaghtigh E, Greathouse DV, Koeppe RE, Kruijtzer JAW, Liskamp RMJ, de Kruijff B, Killian JA (2001) Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation. Biochemistry 40:5000-5010
6. Doherty T, Waring A, Hong M (2006) Membrane-bound conformation and topology of the antimicrobial peptide tachyplesin I by solid-state NMR. Biochemistry 45:13323-13330
7. Gallagher GJ, Hong M, Thompson LK (2004) Solid-state NMR spin diffusion for measurement of membrane-bound peptide structure: gramicidin A. Biochemistry 43:7899-7906
8. Gullion T (1998) Introduction to rotational-echo, double-resonance NMR. Concept Magn Reson 10:277-289
9. Gullion T (1999) A comparison between REDOR and θ-REDOR for measuring 13C-2D dipolar interactions in solids. J Magn Reson 139:402-407
10. Gullion T, Kishore R, Asakura T (2003) Determining dihedral angles and local structure in silk peptide by 13C-2H REDOR. J Am Chem Soc 125:7510-7511
11. Han X, Tamm LK (2000) A host-guest system to study structure-function relationships of membrane fusion peptides. Proc Natl Acad Sci USA 97:13097-13102
12. Hirsh DJ, Lazaro N, Wright LR, Boggs JM, McIntosh TJ, Schaefer J, Blazyk J (1998) A new monofluorinated phosphatidylcholine forms interdigitated bilayers. Biophys J 75:1858-1868
13. Huster D, Yao XL, Hong M (2002) Membrane protein topology probed by H-1 spin diffusion from lipids using solid-state NMR spectroscopy. J Am Chem Soc 124:874-883
14. Jaroniec CP, Tounge BA, Rienstra CM, Herzfeld J, Griffin RG (1999) Measurement of 13C-13-15 N distances in uniformly 13C labeled biomolecules: j-decoupled REDOR. J Am Chem Soc 121:10237-10238
15. Long HW, Tycko R (1998) Biopolymer conformational distributions from solid-state NMR: alpha-helix and 3(10)-helix contents of a helical peptide. J Am Chem Soc 120:7039-7048
16. McDermott A (2009) Structure and dynamics of membrane proteins by magic angle spinning solid-state NMR. Ann Rev Biophys 38:385-403
17. Pan JH, Lai CB, Scott WRP, Straus SK (2010) Synthetic fusion peptides of tick-borne encephalitis virus as models for membrane fusion. Biochemistry 49:287-296
18. Qiang W, Bodner ML, Weliky DP (2008) Solid-state NMR spectroscopy of human immunodeficiency virus fusion peptides associated with host-cell-like membranes: 2D correlation spectra and distance measurements support a fully extended conformation and models for specific antiparallel strand registries. J Am Chem Soc 130:5459-5471
19. Qiang W, Sun Y, Weliky DP (2009) A strong correlation between fusogenicity and membrane insertion depth of the HIV fusion peptide. Proc Natl Acad Sci USA 106:15314-15319
20. 2H-dephased REDOR. J Am Chem Soc 122:12263-12269
21. 13C labels. J Magn Reson 137:272-275
22. Schmidt A, McKay RA, Schaefer J (1992) Internuclear distance measurement between deuterium (I = 1) and a spin-1/2 nucleus in rotating solids. J Magn Reson 96:644-650
23. Toke O, Maloy WL, Kim SJ, Blazyk J, Schaefer J (2004) Secondary structure and lipid contact of a peptide antibiotic in phospholipid bilayers by REDOR. Biophys J 87:662-674
24. Tristram-Nagle S, Nagle JF (2004) Lipid bilayers: thermodynamics, structure, fluctuations, and interactions. Chem Phys Lipids 127:3-14
25. White JM, Delos SE, Brecher M, Schornberg K (2008) Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. Crit Rev Biochem Mol Biol 43:189-219
26. Yang J, Gabrys CM, Weliky DP (2001) Solid-state nuclear magnetic resonance evidence for an extended beta strand conformation of the membrane-bound HIV-1 fusion peptide. Biochemistry 40:8126-8137
27. Yang J, Parkanzky PD, Bodner ML, Duskin CG, Weliky DP (2002) Application of REDOR subtraction for filtered MAS observation of labeled backbone carbons of membrane-bound fusion peptides. J Magn Reson 159:101-110
28. Zhang HY, Neal S, Wishart DS (2003) RefDB: a database of uniformly referenced protein chemical shifts. J Biomol NMR 25:173-195
29. Zheng Z, Yang R, Bodner ML, Weliky DP (2006) Conformational flexibility and strand arrangements of the membrane-Associated HIV fusion peptide trimer probed by solid-state NMR spectroscopy. Biochemistry 45:12960-12975