Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models

BMC Bioinformatics

Volumn 14, Issue 1, 2013, Pages

  Cotten, Cameron ^a,b   Reed, Jennifer L ^a,b  

^a University of Wisconsin Madison   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Central metabolism; Constraint based; FBA; Kinetics; Metabolic engineering

Indexed keywords

BIOMASS YIELD; CENTRAL METABOLISMS; CONCENTRATION DATA; CONFIDENCE INTERVAL; CONSTRAINT-BASED; CONSTRAINT-BASED MODELING; CONSTRAINT-BASED MODELS; ENZYME CONCENTRATIONS; EXPERIMENTAL CONDITIONS; EXPERIMENTAL MEASUREMENTS; FBA; FLUX LIMITS; GIBBS FREE ENERGY CHANGES; IN-VIVO; INTEGRATED ANALYSIS; KINETIC CONSTRAINTS; KINETIC MODELS; KINETIC RATE LAW; MASS BALANCE; MECHANISTIC ANALYSIS; METABOLIC MODELS; METABOLITE CONCENTRATIONS; NEW PARAMETERS; PARAMETER VALUES; STANDARD DEVIATION; THERMODYNAMIC CONSTRAINTS; TRAINING DATASET; TRAINING SETS; TRANSCRIPTIONAL REGULATION;

ENZYME KINETICS; ENZYMES; ESCHERICHIA COLI; FORECASTING; KINETIC THEORY; METABOLIC ENGINEERING; METABOLISM; METABOLITES; PARAMETER ESTIMATION; PHYSIOLOGY;

KINETIC PARAMETERS;

ESCHERICHIA COLI;

ARTICLE; BIOLOGICAL MODEL; BIOMASS; ESCHERICHIA COLI; KINETICS; METABOLISM; METABOLOMICS; METHODOLOGY; PROTEOMICS; THERMODYNAMICS;

BIOMASS; ESCHERICHIA COLI; KINETICS; METABOLOMICS; MODELS, BIOLOGICAL; PROTEOMICS; THERMODYNAMICS;

EID: 84873053978     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-14-32     Document Type: Article

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