The 3-hydroxy-methylglutaryl coenzyme a lyase HCL1 is required for macrophage colonization by human fungal pathogen histoplasma capsulatum

Infection and Immunity

Volumn 81, Issue 2, 2013, Pages 411-420

  Isaac, Dervla T ^a   Coady, Alison ^a   Prooyen, Nancy ^a   Sil, Anita ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY METHYLGLUTARYL COENZYME A LYASE; LYASE; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDURIA; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLUS NIDULANS; CARBON SOURCE; CATABOLISM; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FUNGAL COLONIZATION; GENE FUNCTION; GENOTYPE; HISTOPLASMA CAPSULATUM; HISTOPLASMOSIS; HOST CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; METABOLIC ACIDOSIS; MOUSE; NONHUMAN; PHAGOLYSOSOME; PHAGOSOME; PRIORITY JOURNAL; SURVIVAL TIME; TIME OF DEATH;

ACETYL-COA C-ACETYLTRANSFERASE; AMINO ACID METABOLISM, INBORN ERRORS; AMINO ACID SEQUENCE; ANIMALS; FEMALE; HISTOPLASMA; HISTOPLASMOSIS; HUMANS; HYDROGEN-ION CONCENTRATION; LEUCINE; MACROPHAGES; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; OXO-ACID-LYASES; PHAGOSOMES;

EID: 84873047044     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00833-12     Document Type: Article

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