메뉴 건너뛰기




Volumn 87, Issue 3, 2013, Pages 1899-1905

Trimeric glycosylphosphatidylinositol-anchored HCDR3 of broadly neutralizing antibody PG16 Is a potent HIV-1 entry inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED HCDR3; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; NEUTRALIZING ANTIBODY PG16; UNCLASSIFIED DRUG;

EID: 84873033034     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01038-12     Document Type: Article
Times cited : (13)

References (27)
  • 2
    • 77954982131 scopus 로고    scopus 로고
    • Crystal structure of PG16 and chimeric dissection with somatically related PG9: structurefunction analysis of two quaternary-specific antibodies that effectively neutralize HIV-1
    • Pancera M, McLellan JS, Wu X, Zhu J, Changela A, Schmidt SD, Yang Y, Zhou T, Phogat S, Mascola JR, Kwong PD. 2010. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structurefunction analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J. Virol. 84:8098-8110.
    • (2010) J. Virol. , vol.84 , pp. 8098-8110
    • Pancera, M.1    McLellan, J.S.2    Wu, X.3    Zhu, J.4    Changela, A.5    Schmidt, S.D.6    Yang, Y.7    Zhou, T.8    Phogat, S.9    Mascola, J.R.10    Kwong, P.D.11
  • 4
    • 80052284226 scopus 로고    scopus 로고
    • Potent and broad anti-HIV-1 activity exhibited by a glycosyl-phosphatidylinositol-anchored peptide derived from the CDR H3 of broadly neutralizing antibody PG16
    • Liu L, Wen M, Wang W, Wang S, Yang L, Liu Y, Qian M, Zhang L, Shao Y, Kimata JT, Zhou P. 2011. Potent and broad anti-HIV-1 activity exhibited by a glycosyl-phosphatidylinositol-anchored peptide derived from the CDR H3 of broadly neutralizing antibody PG16. J. Virol. 85: 8467-8476.
    • (2011) J. Virol. , vol.85 , pp. 8467-8476
    • Liu, L.1    Wen, M.2    Wang, W.3    Wang, S.4    Yang, L.5    Liu, Y.6    Qian, M.7    Zhang, L.8    Shao, Y.9    Kimata, J.T.10    Zhou, P.11
  • 5
    • 77957198704 scopus 로고    scopus 로고
    • Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16
    • Doores KJ, Burton DR. 2010. Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16. J. Virol. 84:10510 -10521.
    • (2010) J. Virol. , vol.84
    • Doores, K.J.1    Burton, D.R.2
  • 6
    • 0021713655 scopus 로고
    • Inhibition of complement activation on the surface of cells after incorporation of decayaccelerating factor (DAF) into their membranes
    • Medof ME, Kinoshita T, Nussenzweig V. 1984. Inhibition of complement activation on the surface of cells after incorporation of decayaccelerating factor (DAF) into their membranes. J. Exp. Med. 160:1558- 1578.
    • (1984) J. Exp. Med. , vol.160
    • Medof, M.E.1    Kinoshita, T.2    Nussenzweig, V.3
  • 8
    • 0031570687 scopus 로고    scopus 로고
    • Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain
    • Tao Y, Strelkov SV, Mesyanzhinov VV, Rossmann MG. 1997. Structure of bacteriophage T4 fibritin: a segmented coiled coil and the role of the C-terminal domain. Structure 5:789 -798.
    • (1997) Structure , vol.5
    • Tao, Y.1    Strelkov, S.V.2    Mesyanzhinov, V.V.3    Rossmann, M.G.4
  • 9
    • 0024435050 scopus 로고
    • Mutational analysis of the cleavage sequence of the human immunodeficiency virus type 1 envelope glycoprotein precursor gp160
    • Freed EO, Myers DJ, Risser R. 1989. Mutational analysis of the cleavage sequence of the human immunodeficiency virus type 1 envelope glycoprotein precursor gp160. J. Virol. 63:4670-4675.
    • (1989) J. Virol. , vol.63 , pp. 4670-4675
    • Freed, E.O.1    Myers, D.J.2    Risser, R.3
  • 10
    • 1642363339 scopus 로고    scopus 로고
    • Very fast folding and association of a trimerization domain from bacteriophage T4 fibritin
    • Guthe S, Kapinos L, Moglich A, Meier S, Grzesiek S, Kiefhaber T. 2004. Very fast folding and association of a trimerization domain from bacteriophage T4 fibritin. J. Mol. Biol. 337:905-915.
    • (2004) J. Mol. Biol. , vol.337 , pp. 905-915
    • Guthe, S.1    Kapinos, L.2    Moglich, A.3    Meier, S.4    Grzesiek, S.5    Kiefhaber, T.6
  • 11
    • 0036231093 scopus 로고    scopus 로고
    • Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin
    • Yang X, Lee J, Mahony EM, Kwong PD, Wyatt R, Sodroski J. 2002. Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin. J. Virol. 76:4634-4642.
    • (2002) J. Virol. , vol.76 , pp. 4634-4642
    • Yang, X.1    Lee, J.2    Mahony, E.M.3    Kwong, P.D.4    Wyatt, R.5    Sodroski, J.6
  • 12
    • 0034040751 scopus 로고    scopus 로고
    • Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
    • Follenzi A, Ailles LE, Bakovic S, Geuna M, Naldini L. 2000. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat. Genet. 25:217-222.
    • (2000) Nat. Genet. , vol.25 , pp. 217-222
    • Follenzi, A.1    Ailles, L.E.2    Bakovic, S.3    Geuna, M.4    Naldini, L.5
  • 13
    • 0025815375 scopus 로고
    • Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication- competent and -defective viral genomes
    • Li Y, Kappes JC, Conway JA, Price RW, Shaw GM, Hahn BH. 1991.Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication- competent and -defective viral genomes. J. Virol. 65:3973-3985.
    • (1991) J. Virol. , vol.65 , pp. 3973-3985
    • Li, Y.1    Kappes, J.C.2    Conway, J.A.3    Price, R.W.4    Shaw, G.M.5    Hahn, B.H.6
  • 14
    • 77957300589 scopus 로고    scopus 로고
    • GPIanchored single chain Fv-an effective way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike
    • Wen M, Arora R, Wang H, Liu L, Kimata JT, Zhou P. 2010. GPIanchored single chain Fv-an effective way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike. Retrovirology 7:79. doi: 10.1186/1742-4690-7-79.
    • (2010) Retrovirology , vol.7 , pp. 79
    • Wen, M.1    Arora, R.2    Wang, H.3    Liu, L.4    Kimata, J.T.5    Zhou, P.6
  • 15
    • 0028853961 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
    • He J, Choe S, Walker R, Di Marzio P, Morgan DO, Landau NR. 1995. Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity. J. Virol. 69:6705- 6711.
    • (1995) J. Virol. , vol.69
    • He, J.1    Choe, S.2    Walker, R.3    Di Marzio, P.4    Morgan, D.O.5    Landau, N.R.6
  • 17
    • 0030031568 scopus 로고    scopus 로고
    • Distinct but related human immunodeficiency virus type 1 variant populations in genital secretions and blood
    • Overbaugh J, Anderson RJ, Ndinya-Achola JO, Kreiss JK. 1996. Distinct but related human immunodeficiency virus type 1 variant populations in genital secretions and blood. AIDS Res. Hum. Retroviruses 12:107-115.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 107-115
    • Overbaugh, J.1    Anderson, R.J.2    Ndinya-Achola, J.O.3    Kreiss, J.K.4
  • 18
    • 79954589594 scopus 로고    scopus 로고
    • Genetic and neutralization sensitivity of diverse HIV-1 env clones from chronically infected patients in China
    • Shang H, Han X, Shi X, Zuo T, Goldin M, Chen D, Han B, Sun W, Wu H, Wang X, Zhang L. 2011. Genetic and neutralization sensitivity of diverse HIV-1 env clones from chronically infected patients in China. J. Biol. Chem. 286:14531-14541.
    • (2011) J. Biol. Chem. , vol.286 , pp. 14531-14541
    • Shang, H.1    Han, X.2    Shi, X.3    Zuo, T.4    Goldin, M.5    Chen, D.6    Han, B.7    Sun, W.8    Wu, H.9    Wang, X.10    Zhang, L.11
  • 19
    • 0030062864 scopus 로고    scopus 로고
    • Construction and characterization of a stable fulllength macrophage-tropic HIV type 1 molecular clone that directs the production of high titers of progeny virions
    • Theodore TS, Englund G, Buckler-White A, Buckler CE, Martin MA, Peden KW. 1996. Construction and characterization of a stable fulllength macrophage-tropic HIV type 1 molecular clone that directs the production of high titers of progeny virions. AIDS Res. Hum. Retroviruses 12:191-194.
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 191-194
    • Theodore, T.S.1    Englund, G.2    Buckler-White, A.3    Buckler, C.E.4    Martin, M.A.5    Peden, K.W.6
  • 20
    • 8944259913 scopus 로고    scopus 로고
    • Retrovirus packaging cells based on 10A1 murine leukemia virus for production of vectors that use multiple receptors for cell entry
    • Miller AD, Chen F. 1996. Retrovirus packaging cells based on 10A1 murine leukemia virus for production of vectors that use multiple receptors for cell entry. J. Virol. 70:5564 -5571.
    • (1996) J. Virol. , vol.70
    • Miller, A.D.1    Chen, F.2
  • 21
    • 70350574663 scopus 로고    scopus 로고
    • Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase
    • Tsai C, Caillet C, Hu H, Zhou F, Ding H, Zhang G, Zhou B, Wang S, Lu S, Buchy P, Deubel V, Vogel FR, Zhou P. 2009. Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase. Vaccine 27:6777- 6790.
    • (2009) Vaccine , vol.27
    • Tsai, C.1    Caillet, C.2    Hu, H.3    Zhou, F.4    Ding, H.5    Zhang, G.6    Zhou, B.7    Wang, S.8    Lu, S.9    Buchy, P.10    Deubel, V.11    Vogel, F.R.12    Zhou, P.13
  • 22
    • 0032922339 scopus 로고    scopus 로고
    • Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression
    • Kimata JT, Kuller L, Anderson DB, Dailey P, Overbaugh J. 1999. Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression. Nat. Med. 5:535-541.
    • (1999) Nat. Med. , vol.5 , pp. 535-541
    • Kimata, J.T.1    Kuller, L.2    Anderson, D.B.3    Dailey, P.4    Overbaugh, J.5
  • 24
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • Koyanagi Y, Miles S, Mitsuyasu R, Merrill J, Vinters H, Chen I. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.3    Merrill, J.4    Vinters, H.5    Chen, I.6
  • 25
    • 67349164760 scopus 로고    scopus 로고
    • NMR structure of a monomeric intermediate on the evolutionarily optimized assembly pathway of a small trimerization domain
    • Habazettl J, Reiner A, Kiefhaber T. 2009. NMR structure of a monomeric intermediate on the evolutionarily optimized assembly pathway of a small trimerization domain. J. Mol. Biol. 389:103-114.
    • (2009) J. Mol. Biol. , vol.389 , pp. 103-114
    • Habazettl, J.1    Reiner, A.2    Kiefhaber, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.