Decreased microRNA-30a levels are associated with enhanced ABL1 and BCR-ABL1 expression in chronic myeloid leukemia

Leukemia Research

Volumn 37, Issue 3, 2013, Pages 349-356

  Liu, Yue ^a   Song, Yanbin ^a   Ma, Wenli ^a   Zheng, Wenling ^a   Yin, Hong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

BCR ABL1; Cell cycle; Cell proliferation; Chronic myeloid leukemia (CML); MiR 30a; Tumor suppressor

Indexed keywords

ABELSON KINASE; ABELSON KINASE 1; BCR ABL PROTEIN; BCR ABL1 PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 30A; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMOGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; UPREGULATION;

CASE-CONTROL STUDIES; CELLS, CULTURED; DOWN-REGULATION; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, ABL; GENES, TUMOR SUPPRESSOR; HUMANS; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICRORNAS; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84872982288     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.12.003     Document Type: Article

References (26)

1. Chitwood D.H., Timmermans M.C. Small RNAs are on the move. Nature 2010, 467:415-419.
2. Lujambio A., Lowe S.W. The microcosmos of cancer. Nature 2012, 482:347-355.
3. Yendamuri S., Calin G.A. The role of microRNA in human leukemia: a review. Leukemia 2009, 23:1257-1263.
4. Quintas-Cardama A., Cortes J. Molecular biology of bcr-abl1-positive chronic myeloid leukemia. Blood 2009, 113:1619-1630.
5. Ren R. Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 2005, 5:172-183.
6. Van Etten R.A. Oncogenic signaling: new insights and controversies from chronic myeloid leukemia. J Exp Med 2007, 204:461-465.
7. Bueno M.J., Perez de Castro I., Gomez de Cedron M., Santos J., Calin G.A., Cigudosa J.C., et al. Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell 2008, 13:496-506.
8. Iraci N., Valli E., Gherardi S., Soverini S., Kalebic T., Baccarani M., et al. Suppression of BCR-ABL expression in CML by a panel of miRNAs (abstract). Blood 2009, 114:351.
9. Lopotova T., Zackova M., Klamova H., Moravcova J. MicroRNA-451 in chronic myeloid leukemia: miR-451-BCR-ABL regulatory loop?. Leuk Res 2011, 35:974-977.
10. Thomas M., Lieberman J., Lal A. Desperately seeking microRNA targets. Nat Struct Mol Biol 2010, 17:1169-1174.
11. Yu Y., Yang L., Zhao M., Zhu S., Kang R., Vernon P., et al. Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells. Leukemia 2012, 26:1752-1760.
12. Lewis B.P., Burge C.B., Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20.
13. Lall S., Grun D., Krek A., Chen K., Wang Y.L., Dewey C.N., et al. A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol 2006, 16:460-471.
14. Frka K., Facchinello N., Del Vecchio C., Carpi A., Curtarello M., Venerando R., et al. Lentiviral-mediated RNAi in vivo silencing of Col6a1, a gene with complex tissue specific expression pattern. J Biotechnol 2009, 141:8-17.
15. Ballabeni A., Park I.H., Zhao R., Wang W., Lerou P.H., Daley G.Q., et al. Cell cycle adaptations of embryonic stem cells. Proc Natl Acad Sci U S A 2011, 108:19252-19257.
16. Harlow E., Lane D. Antibodies: A Laboratory Manual. Cold Spring Harbor 1988, Cold Spring Harbor Press, NY.
17. Yang Y., Li X., Yang Q., Wang X., Zhou Y., Jiang T., et al. The role of microRNA in human lung squamous cell carcinoma. Cancer Genet Cytogenet 2010, 200:127-133.
18. Meng X.Z., Zheng T.S., Chen X., Wang J.B., Zhang W.H., Pan S.H., et al. microRNA expression alteration after arsenic trioxide treatment in HepG-2 cells. J Gastroenterol Hepatol 2011, 26:186-193.
19. Harvey S.J., Jarad G., Cunningham J., Goldberg S., Schermer B., Harfe B.D., et al. Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol 2008, 19:2150-2158.
20. Patnaik S.K., Kannisto E., Yendamuri S. Overexpression of microRNA miR-30a or miR-191 in A549 lung cancer or BEAS-2B normal lung cell lines does not alter phenotype. PLoS ONE 2010, 5:e9219.
21. Baffa R., Fassan M., Volinia S., O'Hara B., Liu C.G., Palazzo J.P., et al. MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol 2009, 219:214-221.
22. Zaragosi L.E., Wdziekonski B., Brigand K.L., Villageois P., Mari B., Waldmann R., et al. Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol 2011, 12:R64.
23. Kumarswamy R., Mudduluru G., Ceppi P., Muppala S., Kozlowski M., Niklinski J., et al. MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer. Int J Cancer 2012, 130:2044-2053.
24. Zhu H., Wu H., Liu X., Li B., Chen Y., Ren X., et al. Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy 2009, 5:816-823.
25. Baraniskin A., Birkenkamp-Demtroder K., Maghnouj A., Zollner H., Munding J., Klein-Scory S., et al. MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. Carcinogenesis 2012, 33:732-739.
26. Martinez I., Cazalla D., Almstead L.L., Steitz J.A., DiMaio D. miR-29 and miR-30 regulate B-Myb expression during cellular senescence. Proc Natl Acad Sci U S A 2011, 108:522-527.