Insulin resistance in non-diabetic patients of chronic Hepatitis C

Pakistan Journal of Medical Sciences

Volumn 29, Issue 1, 2012, Pages 201-204

  Kiran, Zareen ^a   Zuberi, Bader Faiyaz ^a   Anis, Daniah ^a   Qadeer, Rashid ^a   Hassan, Khalid ^a   Afsar, Salahuddin ^a  

^a DOW UNIVERSITY OF HEALTH SCIENCES   (Pakistan)

Author keywords

Chronic hepatitis c infection; Diabetes mellitus; HOMA IR; Insulin resistance

Indexed keywords

GLUCOSE; INSULIN;

ADULT; AGE DISTRIBUTION; ARTICLE; BODY MASS; CLINICAL ASSESSMENT TOOL; DISEASE ASSOCIATION; FEMALE; GLUCOSE BLOOD LEVEL; HEPATITIS C; HOMEOSTATIC MODEL ASSESSMENT OF INSULIN ESISTANCE; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; OBESITY; PAKISTAN; PREVALENCE; SEX DIFFERENCE;

EID: 84872979944     PISSN: 1682024X     EISSN: None     Source Type: Journal    
DOI: 10.12669/pjms.291.2888     Document Type: Article

References (20)

1. Persico M, Masarone M, La Mura V, Persico E, Moschella F, Svelto M, et al. Clinical expression of insulin resistance in hepatitis C and B virus-related chronic hepatitis: differences and similarities. World J Gastroenterol. 2009;15:462-466.
2. Serfaty L, Capeau J. Hepatitis C, insulin resistance and diabetes: clinical and pathogenic data. Liver Int. 2009;29(Suppl 2):13-25.
3. Machado MV, Cortez-Pinto H. Insulin resistance and steatosis in chronic hepatitis C. Ann Hepatol. 2009;8(Suppl 1):S67-75.
4. Negro F, Clement S. Impact of obesity, steatosis and insulin resistance on progression and response to therapy of hepatitis C. J Viral Hepat. 2009;16:681-688.
5. Delgado-Borrego A, Jordan SH, Negre B, Healey D, Lin W, Kamegaya Y, et al. Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial. Clin Gastroenterol Hepatol. 2010;8:458-462.
6. Deltenre P, Louvet A, Lemoine M, Mourad A, Fartoux L, Moreno C, et al. Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: A meta-analysis. J Hepatol. 2011;55(6):1187-1194.
7. Kawaguchi T, Taniguchi E, Itou M, Sumie S, Yamagishi SI, Sata M. The Pathogenesis, Complications and Therapeutic Strategy for Hepatitis C Virus-associated Insulin Resistance in the Era of Anti-viral Treatment. Rev Recent Clin Trials. 2010;5(3):147-157.
8. Kawaguchi T, Sata M. Importance of hepatitis C virusassociated insulin resistance: therapeutic strategies for insulin sensitization. World J Gastroenterol. 2010;16:1943-1952.
9. Imai K, Takai K, Nishigaki Y, Shimizu S, Naiki T, Hayashi H, et al. Insulin resistance raises the risk for recurrence of stage I hepatocellular carcinoma after curative radiofrequency ablation in hepatitis C virus-positive patients: A prospective, case series study. Hepatol Res. 2010;40:376-382.
10. Vasques AC, Rosado LE, Cassia GR, Geloneze B. Critical analysis on the use of the homeostasis model assessment (HOMA) indexes in the evaluation of the insulin resistance and the pancreatic beta cells functional capacity. Arq Bras Endocrinol Metabol. 2008;52:32-39.
11. Negro F, Alaei M. Hepatitis C virus and type 2 diabetes. World J Gastroenterol. 2009;15:1537-1547.
12. Hung CH, Wang JH, Hu TH, Chen CH, Chang KC, Yen YH, et al. Insulin resistance is associated with hepatocellular carcinoma in chronic hepatitis C infection. World J Gastroenterol. 2010;16:2265-2271.
13. Duseja A, Dhiman RK, Chawla Y, Thumburu KK, Kumar A, Das A, et al. Insulin resistance is common in patients with predominantly genotype 3 chronic hepatitis C. Dig Dis Sci. 2009;54:1778-1782.
14. Khattab M, Eslam M, Sharwae MA, Shatat M, Ali A, Hamdy L. Insulin Resistance Predicts Rapid Virologic Response to Peginterferon/Ribavirin Combination Therapy in Hepatitis C Genotype 4 Patients. Am J Gastroenterol. 2010;105(9):1970-1977.
15. Westin J, Lagging M, Dhillon AP, Norkrans G, Romero AI, Pawlotsky JM, et al. Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection. J Viral Hepat. 2007;14:29-35.
16. White DL, Ratziu V, El-Serag HB. Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis. J Hepatol. 2008;49:831-844.
17. Hui JM, Sud A, Farrell GC, Bandara P, Byth K, Kench JG, et al. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression. Gastroenterology. 2003;125:1695-1704.
18. Kim E. Insulin resistance at the crossroads of metabolic syndrome: systemic analysis using microarrays. Biotechnol J. 2010;5:919-929.
19. Maassen JA, Romijn JA, Heine RJ. Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: a new concept in the pathogenesis of obesity-associated type 2 diabetes mellitus. Diabetologia. 2007;50:2036-2041.
20. Krotkiewski M. Role of muscle morphology in the development of insulin resistance and metabolic syndrome. Presse Med. 1994;23:1393-1399.