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Volumn 18, Issue 52, 2012, Pages 16828-16835

Squaric acid mediated chemoselective PEGylation of proteins: Reactivity of single-step-activated α-amino poly(ethylene glycol)s

(5) Dingels, Carsten a Wurm, Frederik b,c Wagner, Manfred c Klok, Harm Anton b Frey, Holger a

a JOHANNES GUTENBERG UNIVERSITY (Germany)

b EPFL (Switzerland)

c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH (Germany)

Author keywords

chemoselectivity; kinetics; PEGylation; proteins; squaric acid

Indexed keywords

ALIPHATIC COMPOUNDS; AMIDES; AMINO ACIDS; CHEMICAL ACTIVATION; ENZYME KINETICS; ESTERS; ETHYLENE GLYCOL; MAMMALS; POLYOLS; PROTEINS;

AMINO ACID RESIDUES; BOVINE SERUM ALBUMINS; CHEMO-SELECTIVITY; COVALENT ATTACHMENT; HYDROLYTIC STABILITY; PEGYLATION; SINGLE-STEP ACTIVATION; SQUARIC ACIDS;

POLYETHYLENE GLYCOLS;

EID: 84872969824 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201200182 Document Type: Article

Times cited : (27)

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