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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 4, 2013, Pages 1110-1113

Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency

(6) Bollini, Mariela a Gallardo Macias, Ricardo a Spasov, Krasimir A b Tirado Rives, Julian a Anderson, Karen S b Jorgensen, William L a

a YALE UNIVERSITY (United States)

b YALE UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

Anti HIV agents; Computer aided drug design; Free energy calculations; NNRTIs

Indexed keywords

ANTIVIRUS AGENT; BENZYLOXAZOLE DERIVATIVE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENERGY YIELD; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PROCESS OPTIMIZATION;

ANTI-HIV AGENTS; DRUG DESIGN; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MODELS, MOLECULAR; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84872895784 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.11.115 Document Type: Article

Times cited : (18)

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