A comparative protease stability study of synthetic macrocyclic peptides that mimic two endocrine hormones

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 4, 2013, Pages 989-995

  Ferrie, John J ^a   Gruskos, Jessica J ^a   Goldwaser, Ari L ^a   Decker, Megan E ^a   Guarracino, Danielle A ^a  

^a The College of New Jersey   (United States)

Author keywords

Cyclic peptides; Drug design; Head to tail cyclization; Peptide pharmaceuticals; Protease stability

Indexed keywords

CHYMOTRYPSIN A; GLUTATHIONE; OT MIMIC1; OXYTOCIN; PEPSIN A; PEPTIDOMIMETIC AGENT; PRONASE; UNCLASSIFIED DRUG; VASOPRESSIN; VP MIMIC1; VP MIMIC2;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DEGRADATION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY;

ARGININE VASOPRESSIN; BIOMIMETIC MATERIALS; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; ENZYME STABILITY; HUMANS; MACROCYCLIC COMPOUNDS; MODELS, MOLECULAR; OXYTOCIN; PEPTIDE HYDROLASES; PEPTIDES, CYCLIC;

EID: 84872895206     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.12.041     Document Type: Article

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