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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 21, 2012, Pages 6770-6772

Cyclic tetrapeptides with thioacetate tails or intramolecular disulfide bridge as potent inhibitors of histone deacetylases

(6) Hoque, Md Ashraful a Arai, Toru a Nishino, Norikazu a Kim, Hyun Jung b Ito, Akihiro c Yoshida, Minoru c

a KYUSHU INSTITUTE OF TECHNOLOGY (Japan)

b BioRunx Co Ltd (South Korea)

c RIKEN (Japan)

Author keywords

Chlamydocin; Cyclic peptide; Disulfide bridge; FK228; HDAC inhibitor

Indexed keywords

ACETIC ACID DERIVATIVE; DISULFIDE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; TETRAPEPTIDE; THIOACETATE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DISULFIDE BOND; DRUG SYNTHESIS; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISULFIDES; HISTONE DEACETYLASE INHIBITORS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; SULFHYDRYL COMPOUNDS;

EID: 84867582251 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.03.004 Document Type: Article

Times cited : (10)

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