-
2
-
-
0025906014
-
Cloning of a factor required for activity of the Ah (dioxin) receptor
-
Hoffman E.C., Reyes H., Chu F.F., Sander F., Conley L.H., Brooks B.A., Hankinson O. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science 1991, 252:954-958.
-
(1991)
Science
, vol.252
, pp. 954-958
-
-
Hoffman, E.C.1
Reyes, H.2
Chu, F.F.3
Sander, F.4
Conley, L.H.5
Brooks, B.A.6
Hankinson, O.7
-
3
-
-
27544434863
-
Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes
-
Fujii Kuriyama Y., Mimura J. Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes. Biochem. Biophys. Res. Commun. 2005, 338:311-317.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 311-317
-
-
Fujii Kuriyama, Y.1
Mimura, J.2
-
4
-
-
0034723264
-
Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest
-
Puga A., Barnes S.J., Dalton T.P., Chang C., Knudsen E.S., Maier M.A. Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem. 2000, 275:2943-2950.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2943-2950
-
-
Puga, A.1
Barnes, S.J.2
Dalton, T.P.3
Chang, C.4
Knudsen, E.S.5
Maier, M.A.6
-
5
-
-
0038100188
-
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
-
Ohtake F., Takeyama K., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., Tohyama C., Krust A., Mimura J., Chambon P., Yanagisawa J., Kato S., Fujii Kuriyama Y. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 2003, 423:545-550.
-
(2003)
Nature
, vol.423
, pp. 545-550
-
-
Ohtake, F.1
Takeyama, K.2
Matsumoto, T.3
Kitagawa, H.4
Yamamoto, Y.5
Nohara, K.6
Tohyama, C.7
Krust, A.8
Mimura, J.9
Chambon, P.10
Yanagisawa, J.11
Kato, S.12
Fujii Kuriyama, Y.13
-
6
-
-
75149130980
-
Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation
-
Hall J.M., Barhoover M.A., Kazmin D., McDonnell D.P., Greenlee W.F., Thomas R.S. Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. Mol. Endocrinol. 2010, 24:359-369.
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 359-369
-
-
Hall, J.M.1
Barhoover, M.A.2
Kazmin, D.3
McDonnell, D.P.4
Greenlee, W.F.5
Thomas, R.S.6
-
7
-
-
84856594204
-
Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells
-
Zhao S., Kanno Y., Nakayama M., Makimura M., Ohara S., Inouye Y. Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells. Cancer Lett. 2012, 317:192-198.
-
(2012)
Cancer Lett.
, vol.317
, pp. 192-198
-
-
Zhao, S.1
Kanno, Y.2
Nakayama, M.3
Makimura, M.4
Ohara, S.5
Inouye, Y.6
-
8
-
-
78149487540
-
Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist
-
Prud'homme G.J., Glinka Y., Toulina A., Ace O., Subramaniam V., Jothy S. Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist. PLoS One 2010, 5:e13831.
-
(2010)
PLoS One
, vol.5
-
-
Prud'homme, G.J.1
Glinka, Y.2
Toulina, A.3
Ace, O.4
Subramaniam, V.5
Jothy, S.6
-
9
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P., Hunter T. Oncogenic kinase signalling. Nature 2001, 411:355-365.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
10
-
-
0034638925
-
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
-
Harari D., Yarden Y. Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 2000, 19:6102-6114.
-
(2000)
Oncogene
, vol.19
, pp. 6102-6114
-
-
Harari, D.1
Yarden, Y.2
-
11
-
-
79959917275
-
HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis
-
Hartman Z.C., Yang X.Y., Glass O., Lei G., Osada T., Dave S.S., Morse M.A., Clay T.M., Lyerly H.K. HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis. Cancer Res. 2011, 71:4380-4391.
-
(2011)
Cancer Res.
, vol.71
, pp. 4380-4391
-
-
Hartman, Z.C.1
Yang, X.Y.2
Glass, O.3
Lei, G.4
Osada, T.5
Dave, S.S.6
Morse, M.A.7
Clay, T.M.8
Lyerly, H.K.9
-
12
-
-
33947414063
-
Significance of interleukin-6 (IL-6) in breast cancer (review)
-
Knupfer H., Preiss R. Significance of interleukin-6 (IL-6) in breast cancer (review). Breast Cancer Res. Treat. 2007, 102:129-135.
-
(2007)
Breast Cancer Res. Treat.
, vol.102
, pp. 129-135
-
-
Knupfer, H.1
Preiss, R.2
-
13
-
-
74549170027
-
Dependence on the microtubule network and 90-kDa heat shock protein of phenobarbital-induced nuclear translocation of the rat constitutive androstane receptor
-
Kanno Y., Miyama Y., Ando M., Inouye Y. Dependence on the microtubule network and 90-kDa heat shock protein of phenobarbital-induced nuclear translocation of the rat constitutive androstane receptor. Mol. Pharm. 2010, 77:311-316.
-
(2010)
Mol. Pharm.
, vol.77
, pp. 311-316
-
-
Kanno, Y.1
Miyama, Y.2
Ando, M.3
Inouye, Y.4
-
14
-
-
36849039660
-
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
-
Sansone P., Storci G., Tavolari S., Guarnieri T., Giovannini C., Taffurelli M., Ceccarelli C., Santini D., Paterini P., Bonafe M., Chieco P., Marcu K.B. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J. Clin. Invest. 2007, 117:3988-4002.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3988-4002
-
-
Sansone, P.1
Storci, G.2
Tavolari, S.3
Guarnieri, T.4
Giovannini, C.5
Taffurelli, M.6
Ceccarelli, C.7
Santini, D.8
Paterini, P.9
Bonafe, M.10
Chieco, P.11
Marcu, K.B.12
-
15
-
-
76649113726
-
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
-
Ginestier C., Liu S., Diebel M.E., Korkaya H., Luo M., Brown M., Wicinski J., Cabaud O., Charafe-Jauffret E., Birnbaum D., Guan J.L., Dontu G., Wicha M.S. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J. Clin. Invest. 2010, 120:485-497.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 485-497
-
-
Ginestier, C.1
Liu, S.2
Diebel, M.E.3
Korkaya, H.4
Luo, M.5
Brown, M.6
Wicinski, J.7
Cabaud, O.8
Charafe-Jauffret, E.9
Birnbaum, D.10
Guan, J.L.11
Dontu, G.12
Wicha, M.S.13
-
16
-
-
80053531658
-
Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots
-
Korkaya H., Liu S., Wicha M.S. Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots. Clin. Cancer Res. 2011, 17:6125-6129.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6125-6129
-
-
Korkaya, H.1
Liu, S.2
Wicha, M.S.3
-
17
-
-
43449118697
-
Constitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissue
-
Yang X., Solomon S., Fraser L.R., Trombino A.F., Liu D., Sonenshein G.E., et al. Constitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissue. J. Cell Biochem. 2008, 104:402-417.
-
(2008)
J. Cell Biochem.
, vol.104
, pp. 402-417
-
-
Yang, X.1
Solomon, S.2
Fraser, L.R.3
Trombino, A.F.4
Liu, D.5
Sonenshein, G.E.6
-
18
-
-
1842418966
-
Cell density regulates intracellular localization of aryl hydrocarbon receptor
-
Ikuta T., Kobayashi Y., Kawajiri K. Cell density regulates intracellular localization of aryl hydrocarbon receptor. J. Biol. Chem. 2004, 279:19209-19216.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19209-19216
-
-
Ikuta, T.1
Kobayashi, Y.2
Kawajiri, K.3
-
19
-
-
21544468008
-
Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways
-
Oesch-Bartlomowicz B., Huelster A., Wiss O., Antoniou-Lipfert P., Dietrich C., Arand M., Weiss C., Bockamp E., Oesch F. Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways. Proc. Natl. Acad. Sci. USA 2005, 102:9218-9223.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9218-9223
-
-
Oesch-Bartlomowicz, B.1
Huelster, A.2
Wiss, O.3
Antoniou-Lipfert, P.4
Dietrich, C.5
Arand, M.6
Weiss, C.7
Bockamp, E.8
Oesch, F.9
-
20
-
-
79551688725
-
Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling
-
DiNatale B.C., Murray I.A., Schroeder J.C., Flaveny C.A., Lahoti T.S., Laurenzana E.M., Omiecinski C.J., Perdew G.H. Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicol. Sci. 2010, 115:89-97.
-
(2010)
Toxicol. Sci.
, vol.115
, pp. 89-97
-
-
DiNatale, B.C.1
Murray, I.A.2
Schroeder, J.C.3
Flaveny, C.A.4
Lahoti, T.S.5
Laurenzana, E.M.6
Omiecinski, C.J.7
Perdew, G.H.8
-
21
-
-
77955284187
-
Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling
-
DiNatale B.C., Schroeder J.C., Francey L.J., Kusnadi A., Perdew G.H. Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling. J. Biol. Chem. 2010, 285:24388-24397.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 24388-24397
-
-
DiNatale, B.C.1
Schroeder, J.C.2
Francey, L.J.3
Kusnadi, A.4
Perdew, G.H.5
-
22
-
-
84861369598
-
Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer
-
Chen P.H., Chang H., Chang J.T., Lin P. Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer. Oncogene 2012, 31:2555-2565.
-
(2012)
Oncogene
, vol.31
, pp. 2555-2565
-
-
Chen, P.H.1
Chang, H.2
Chang, J.T.3
Lin, P.4
-
23
-
-
36849010739
-
RelB, a new partner of aryl hydrocarbon receptor-mediated transcription
-
Vogel C.F., Sciullo E., Li W., Wong P., Lazennec G., Matsumura F. RelB, a new partner of aryl hydrocarbon receptor-mediated transcription. Mol. Endocrinol. 2007, 21:2941-2955.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2941-2955
-
-
Vogel, C.F.1
Sciullo, E.2
Li, W.3
Wong, P.4
Lazennec, G.5
Matsumura, F.6
-
24
-
-
79959819008
-
Interaction of aryl hydrocarbon receptor and NF-kappaB subunit RelB in breast cancer is associated with interleukin-8 overexpression
-
Vogel C.F., Li W., Wu D., Miller J.K., Sweeney C., Lazennec G., Fujisawa Y., Matsumura F. Interaction of aryl hydrocarbon receptor and NF-kappaB subunit RelB in breast cancer is associated with interleukin-8 overexpression. Arch. Biochem. Biophys. 2011, 512:78-86.
-
(2011)
Arch. Biochem. Biophys.
, vol.512
, pp. 78-86
-
-
Vogel, C.F.1
Li, W.2
Wu, D.3
Miller, J.K.4
Sweeney, C.5
Lazennec, G.6
Fujisawa, Y.7
Matsumura, F.8
-
25
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
26
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., Wicha M.S. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes. Dev. 2003, 17:1253-1270.
-
(2003)
Genes. Dev.
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
27
-
-
55749106963
-
Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
-
Grimshaw M.J., Cooper L., Papazisis K., Coleman J.A., Bohnenkamp H.R., Chiapero Stanke L., Taylor Papadimitriou J., Burchell J.M. Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells. Breast Cancer Res. 2008, 10:R52.
-
(2008)
Breast Cancer Res.
, vol.10
-
-
Grimshaw, M.J.1
Cooper, L.2
Papazisis, K.3
Coleman, J.A.4
Bohnenkamp, H.R.5
Chiapero Stanke, L.6
Taylor Papadimitriou, J.7
Burchell, J.M.8
-
28
-
-
84865401715
-
Activation of an IL6 inflammatory loop mediates Trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population
-
Korkaya H., Kim G.I., Davis A., Malik F., Henry N.L., Ithimakin S., Quraishi A.A., Tawakkol N., D'Angelo R., Paulson A.K., Chung S., Luther T., Paholak H.J., Liu S., Hassan K.A., Zen Q., Clouthier S.G., Wicha M.S. Activation of an IL6 inflammatory loop mediates Trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population. Mol. Cell 2012, 47:570-584.
-
(2012)
Mol. Cell
, vol.47
, pp. 570-584
-
-
Korkaya, H.1
Kim, G.I.2
Davis, A.3
Malik, F.4
Henry, N.L.5
Ithimakin, S.6
Quraishi, A.A.7
Tawakkol, N.8
D'Angelo, R.9
Paulson, A.K.10
Chung, S.11
Luther, T.12
Paholak, H.J.13
Liu, S.14
Hassan, K.A.15
Zen, Q.16
Clouthier, S.G.17
Wicha, M.S.18
-
29
-
-
54049096261
-
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
-
Korkaya H., Paulson A., Iovino F., Wicha M.S. HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 2008, 27:6120-6130.
-
(2008)
Oncogene
, vol.27
, pp. 6120-6130
-
-
Korkaya, H.1
Paulson, A.2
Iovino, F.3
Wicha, M.S.4
-
30
-
-
77649270350
-
Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling
-
Nakanishi T., Chumsri S., Khakpour N., Brodie A.H., Leyland-Jones B., Hamburger A.W., Ross D.D., Burger A.M. Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling. Br. J. Cancer 2010, 102:815-826.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 815-826
-
-
Nakanishi, T.1
Chumsri, S.2
Khakpour, N.3
Brodie, A.H.4
Leyland-Jones, B.5
Hamburger, A.W.6
Ross, D.D.7
Burger, A.M.8
|