메뉴 건너뛰기




Volumn 29, Issue 2, 2013, Pages 91-99

Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex

Author keywords

Kinetoplastida; MRB1; Protein complexes; RECC; RNA editing; Trypanosome

Indexed keywords

MITOCHONDRIAL RNA; MITOCHONDRIAL RNA BINDING COMPLEX 1; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; URIDINE;

EID: 84872865493     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2012.11.005     Document Type: Review
Times cited : (50)

References (45)
  • 1
    • 0022552305 scopus 로고
    • Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA
    • Benne R., et al. Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA. Cell 1986, 46:819-826.
    • (1986) Cell , vol.46 , pp. 819-826
    • Benne, R.1
  • 2
    • 0025189769 scopus 로고
    • A model for RNA editing in kinetoplastid mitochondria: 'guide' RNA molecules transcribed from maxicircle DNA provide the edited information
    • Blum B., et al. A model for RNA editing in kinetoplastid mitochondria: 'guide' RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 1990, 60:189-198.
    • (1990) Cell , vol.60 , pp. 189-198
    • Blum, B.1
  • 3
    • 0027942565 scopus 로고
    • RNA editing: transfer of genetic information from gRNA to precursor mRNA in vitro
    • Seiwert S.D., Stuart K. RNA editing: transfer of genetic information from gRNA to precursor mRNA in vitro. Science 1994, 266:114-117.
    • (1994) Science , vol.266 , pp. 114-117
    • Seiwert, S.D.1    Stuart, K.2
  • 4
    • 1642580825 scopus 로고    scopus 로고
    • Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing
    • Simpson L., et al. Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA 2004, 10:159-170.
    • (2004) RNA , vol.10 , pp. 159-170
    • Simpson, L.1
  • 5
    • 13244290067 scopus 로고    scopus 로고
    • Complex management: RNA editing in trypanosomes
    • Stuart K.D., et al. Complex management: RNA editing in trypanosomes. Trends Biochem. Sci. 2005, 30:97-105.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 97-105
    • Stuart, K.D.1
  • 6
    • 79961058405 scopus 로고    scopus 로고
    • The remarkable mitochondrion of trypanosomes and related flagellates
    • Springer, W. de Souza (Ed.)
    • LukeŠ J., et al. The remarkable mitochondrion of trypanosomes and related flagellates. Structures and Organelles in Pathogenic Protists 2010, 227-252. Springer. W. de Souza (Ed.).
    • (2010) Structures and Organelles in Pathogenic Protists , pp. 227-252
    • Lukeš, J.1
  • 7
    • 84861474039 scopus 로고    scopus 로고
    • Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens
    • Salavati R., et al. Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens. Int. J. Parasitol. Drugs Drug Res. 2012, 2:36-46.
    • (2012) Int. J. Parasitol. Drugs Drug Res. , vol.2 , pp. 36-46
    • Salavati, R.1
  • 8
    • 42449091992 scopus 로고    scopus 로고
    • TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex
    • Hashimi H., et al. TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA 2008, 14:970-980.
    • (2008) RNA , vol.14 , pp. 970-980
    • Hashimi, H.1
  • 9
    • 41549134681 scopus 로고    scopus 로고
    • Mitochondrial complexes in Trypanosoma brucei: a novel complex and a unique oxidoreductase complex
    • Panigrahi A.K., et al. Mitochondrial complexes in Trypanosoma brucei: a novel complex and a unique oxidoreductase complex. Mol. Cell. Proteomics 2008, 7:534-545.
    • (2008) Mol. Cell. Proteomics , vol.7 , pp. 534-545
    • Panigrahi, A.K.1
  • 10
    • 44649128170 scopus 로고    scopus 로고
    • 3' Adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria
    • Etheridge R.D., et al. 3' Adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria. EMBO J. 2008, 27:1596-1608.
    • (2008) EMBO J. , vol.27 , pp. 1596-1608
    • Etheridge, R.D.1
  • 11
    • 53949111444 scopus 로고    scopus 로고
    • Guide RNA-binding complex from mitochondria of trypanosomatids
    • Weng J., et al. Guide RNA-binding complex from mitochondria of trypanosomatids. Mol. Cell 2008, 32:198-209.
    • (2008) Mol. Cell , vol.32 , pp. 198-209
    • Weng, J.1
  • 12
    • 62549093977 scopus 로고    scopus 로고
    • Kinetoplastid guide RNA biogenesis is dependent on subunits of the mitochondrial RNA binding complex 1 and mitochondrial RNA polymerase
    • Hashimi H., et al. Kinetoplastid guide RNA biogenesis is dependent on subunits of the mitochondrial RNA binding complex 1 and mitochondrial RNA polymerase. RNA 2009, 15:588-599.
    • (2009) RNA , vol.15 , pp. 588-599
    • Hashimi, H.1
  • 13
    • 74049139574 scopus 로고    scopus 로고
    • REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA (gRNA) binding
    • Hernandez A., et al. REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA (gRNA) binding. J. Biol. Chem. 2010, 285:1220-1228.
    • (2010) J. Biol. Chem. , vol.285 , pp. 1220-1228
    • Hernandez, A.1
  • 14
    • 79955023503 scopus 로고    scopus 로고
    • MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process
    • Ammerman M.L., et al. MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process. RNA 2011, 17:865-877.
    • (2011) RNA , vol.17 , pp. 865-877
    • Ammerman, M.L.1
  • 15
    • 84866614848 scopus 로고    scopus 로고
    • Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei
    • Kafková L., et al. Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei. RNA 2012, 18:1846-1861.
    • (2012) RNA , vol.18 , pp. 1846-1861
    • Kafková, L.1
  • 16
    • 84863197454 scopus 로고    scopus 로고
    • Architecture of the trypanosome RNA editing accessory complex, MRB1
    • Ammerman M.L., et al. Architecture of the trypanosome RNA editing accessory complex, MRB1. Nucleic Acids Res. 2012, 40:5637-5650.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 5637-5650
    • Ammerman, M.L.1
  • 17
    • 58249121139 scopus 로고    scopus 로고
    • The MRB1 complex functions in kinetoplastid RNA processing
    • Acestor N., et al. The MRB1 complex functions in kinetoplastid RNA processing. RNA 2009, 15:277-286.
    • (2009) RNA , vol.15 , pp. 277-286
    • Acestor, N.1
  • 18
    • 53149112760 scopus 로고    scopus 로고
    • TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages
    • Fisk J.C., et al. TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages. J. Biol. Chem. 2008, 283:23016-23025.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23016-23025
    • Fisk, J.C.1
  • 19
    • 78149314216 scopus 로고    scopus 로고
    • TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites
    • Ammerman M.L., et al. TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites. RNA 2010, 16:2239-2251.
    • (2010) RNA , vol.16 , pp. 2239-2251
    • Ammerman, M.L.1
  • 20
    • 84865551421 scopus 로고    scopus 로고
    • Multifunctional G-rich and RRM-containing domains of TbRGG2 perform separate yet essential functions in trypanosome RNA editing
    • Foda B.M., et al. Multifunctional G-rich and RRM-containing domains of TbRGG2 perform separate yet essential functions in trypanosome RNA editing. Eukaryot. Cell 2012, 11:1119-1131.
    • (2012) Eukaryot. Cell , vol.11 , pp. 1119-1131
    • Foda, B.M.1
  • 21
    • 0033977681 scopus 로고    scopus 로고
    • Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA
    • McManus M.T., et al. Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Mol. Cell. Biol. 2000, 20:883-891.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 883-891
    • McManus, M.T.1
  • 22
    • 0023647931 scopus 로고
    • Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma brucei
    • Feagin J.E., et al. Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma brucei. Cell 1987, 49:337-345.
    • (1987) Cell , vol.49 , pp. 337-345
    • Feagin, J.E.1
  • 23
    • 0026710969 scopus 로고
    • The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing
    • Maslov D.A., Simpson L. The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing. Cell 1992, 70:459-467.
    • (1992) Cell , vol.70 , pp. 459-467
    • Maslov, D.A.1    Simpson, L.2
  • 24
    • 79952758367 scopus 로고    scopus 로고
    • Trypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing
    • Li F., et al. Trypanosome REH1 is an RNA helicase involved with the 3'-5' polarity of multiple gRNA-guided uridine insertion/deletion RNA editing. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:3542-3547.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 3542-3547
    • Li, F.1
  • 25
    • 0037053366 scopus 로고    scopus 로고
    • A trypanosome mitochondrial RNA polymerase is required for transcription and replication
    • Grams J., et al. A trypanosome mitochondrial RNA polymerase is required for transcription and replication. J. Biol. Chem. 2002, 277:16952-16959.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16952-16959
    • Grams, J.1
  • 26
    • 80053183723 scopus 로고    scopus 로고
    • Guide RNA biogenesis involves a novel RNase III family endoribonuclease in Trypanosoma brucei
    • Madina B.R., et al. Guide RNA biogenesis involves a novel RNase III family endoribonuclease in Trypanosoma brucei. RNA 2011, 17:1821-1830.
    • (2011) RNA , vol.17 , pp. 1821-1830
    • Madina, B.R.1
  • 27
    • 0031438786 scopus 로고    scopus 로고
    • Mitochondrial mRNA 3' cleavage/polyadenylation and RNA editing in Trypanosoma brucei are independent events
    • Koslowsky D.J., Yahampath G. Mitochondrial mRNA 3' cleavage/polyadenylation and RNA editing in Trypanosoma brucei are independent events. Mol. Biochem. Parasitol. 1997, 90:81-94.
    • (1997) Mol. Biochem. Parasitol. , vol.90 , pp. 81-94
    • Koslowsky, D.J.1    Yahampath, G.2
  • 28
    • 77749325035 scopus 로고    scopus 로고
    • RET1-catalyzed uridylylation shapes the mitochondrial transcriptome in Trypanosoma brucei
    • Aphasizheva I., Aphasizhev R. RET1-catalyzed uridylylation shapes the mitochondrial transcriptome in Trypanosoma brucei. Mol. Cell. Biol. 2010, 30:1555-1567.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 1555-1567
    • Aphasizheva, I.1    Aphasizhev, R.2
  • 29
    • 0025931764 scopus 로고
    • Modification of Trypanosoma brucei mitochondrial rRNA by posttranscriptional 3' polyuridine tail formation
    • Adler B.K., et al. Modification of Trypanosoma brucei mitochondrial rRNA by posttranscriptional 3' polyuridine tail formation. Mol. Cell. Biol. 1991, 11:5878-5884.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5878-5884
    • Adler, B.K.1
  • 30
    • 0025293741 scopus 로고
    • Guide RNAs in kinetoplastid mitochondria have a nonencoded 3' oligo(U) tail involved in recognition of the preedited region
    • Blum B., Simpson L. Guide RNAs in kinetoplastid mitochondria have a nonencoded 3' oligo(U) tail involved in recognition of the preedited region. Cell 1990, 62:391-397.
    • (1990) Cell , vol.62 , pp. 391-397
    • Blum, B.1    Simpson, L.2
  • 31
    • 17844369437 scopus 로고    scopus 로고
    • UTP-dependent turnover of Trypanosoma brucei mitochondrial mRNA requires UTP polymerization and involves the RET1 TUTase
    • Ryan C.M., Read L.K. UTP-dependent turnover of Trypanosoma brucei mitochondrial mRNA requires UTP polymerization and involves the RET1 TUTase. RNA 2005, 11:763-773.
    • (2005) RNA , vol.11 , pp. 763-773
    • Ryan, C.M.1    Read, L.K.2
  • 32
    • 84861302925 scopus 로고    scopus 로고
    • Additive and transcript-specific effects of KPAP1 and TbRND activities on 3' non-encoded tail characteristics and mRNA stability in Trypanosoma brucei
    • Zimmer S.L., et al. Additive and transcript-specific effects of KPAP1 and TbRND activities on 3' non-encoded tail characteristics and mRNA stability in Trypanosoma brucei. PLoS ONE 2012, 7:e37639.
    • (2012) PLoS ONE , vol.7
    • Zimmer, S.L.1
  • 33
    • 14044264228 scopus 로고    scopus 로고
    • Opposing effects of polyadenylation on the stability of edited and unedited mitochondrial RNAs in Trypanosoma brucei
    • Kao C.Y., Read L.K. Opposing effects of polyadenylation on the stability of edited and unedited mitochondrial RNAs in Trypanosoma brucei. Mol. Cell. Biol. 2005, 25:1634-1644.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1634-1644
    • Kao, C.Y.1    Read, L.K.2
  • 34
    • 79953326716 scopus 로고    scopus 로고
    • Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomes
    • Aphasizheva I., et al. Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomes. Mol. Cell 2011, 42:106-117.
    • (2011) Mol. Cell , vol.42 , pp. 106-117
    • Aphasizheva, I.1
  • 35
    • 0035946941 scopus 로고    scopus 로고
    • Comparison of ARM and HEAT protein repeats
    • Andrade M.A., et al. Comparison of ARM and HEAT protein repeats. J. Mol. Biol. 2001, 309:1-18.
    • (2001) J. Mol. Biol. , vol.309 , pp. 1-18
    • Andrade, M.A.1
  • 36
    • 0037276124 scopus 로고    scopus 로고
    • A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components
    • Aphasizhev R., et al. A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components. RNA 2003, 9:62-76.
    • (2003) RNA , vol.9 , pp. 62-76
    • Aphasizhev, R.1
  • 37
    • 11144277396 scopus 로고    scopus 로고
    • The 3'-untranslated region of cytochrome oxidase II mRNA functions in RNA editing of African trypanosomes exclusively as a cis guide RNA
    • Golden D.E., Hajduk S.L. The 3'-untranslated region of cytochrome oxidase II mRNA functions in RNA editing of African trypanosomes exclusively as a cis guide RNA. RNA 2005, 11:29-37.
    • (2005) RNA , vol.11 , pp. 29-37
    • Golden, D.E.1    Hajduk, S.L.2
  • 38
    • 34247506767 scopus 로고    scopus 로고
    • Tandem gene arrays in Trypanosoma brucei: comparative phylogenomic analysis of duplicate sequence variation
    • Jackson A.P. Tandem gene arrays in Trypanosoma brucei: comparative phylogenomic analysis of duplicate sequence variation. BMC Evol. Biol. 2007, 7:54.
    • (2007) BMC Evol. Biol. , vol.7 , pp. 54
    • Jackson, A.P.1
  • 39
    • 79959603061 scopus 로고    scopus 로고
    • How a neutral evolutionary ratchet can build cellular complexity
    • LukeŠ J., et al. How a neutral evolutionary ratchet can build cellular complexity. IUBMB Life 2011, 63:528-537.
    • (2011) IUBMB Life , vol.63 , pp. 528-537
    • Lukeš, J.1
  • 40
    • 47849100472 scopus 로고    scopus 로고
    • Trypanosoma brucei mitochondrial ribosomes: affinity purification and component identification by mass spectrometry
    • Zíková A., et al. Trypanosoma brucei mitochondrial ribosomes: affinity purification and component identification by mass spectrometry. Mol. Cell. Proteomics 2008, 7:1286-1296.
    • (2008) Mol. Cell. Proteomics , vol.7 , pp. 1286-1296
    • Zíková, A.1
  • 41
    • 45349088635 scopus 로고    scopus 로고
    • Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity
    • Ochsenreiter T., et al. Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity. PLoS ONE 2008, 3:e1566.
    • (2008) PLoS ONE , vol.3
    • Ochsenreiter, T.1
  • 42
    • 33646251852 scopus 로고    scopus 로고
    • Is kinetoplastid pan-editing the result of an evolutionary balancing act?
    • Speijer D. Is kinetoplastid pan-editing the result of an evolutionary balancing act?. IUBMB Life 2006, 58:91-96.
    • (2006) IUBMB Life , vol.58 , pp. 91-96
    • Speijer, D.1
  • 43
    • 78149403325 scopus 로고    scopus 로고
    • Cell biology. Irremediable complexity?
    • Gray M.W., et al. Cell biology. Irremediable complexity?. Science 2010, 330:920-921.
    • (2010) Science , vol.330 , pp. 920-921
    • Gray, M.W.1
  • 44
    • 79957595769 scopus 로고    scopus 로고
    • Endonuclease associations with three distinct editosomes in Trypanosoma brucei
    • Carnes J., et al. Endonuclease associations with three distinct editosomes in Trypanosoma brucei. J. Biol. Chem. 2011, 286:19320-19330.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19320-19330
    • Carnes, J.1
  • 45
    • 37549054714 scopus 로고    scopus 로고
    • RNA editing in Trypanosoma brucei requires three different editosomes
    • Carnes J., et al. RNA editing in Trypanosoma brucei requires three different editosomes. Mol. Cell. Biol. 2008, 28:122-130.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 122-130
    • Carnes, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.